Conservation of cofitness between CSW01_12725 and CSW01_03985 in Vibrio cholerae E7946 ATCC 55056

109 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12725 aspartate carbamoyltransferase 1.0 CSW01_03985 GMP synthase (glutamine-hydrolyzing) 0.69 15
Escherichia coli ECOR27 0.76 NOLOHH_04125 pyrB aspartate carbamoyltransferase 0.84 NOLOHH_13415 guaA glutamine-hydrolyzing GMP synthase low > 76
Klebsiella pneumoniae MKP103 0.76 KDGMDA_11465 aspartate carbamoyltransferase 0.84 KDGMDA_28155 glutamine-hydrolyzing GMP synthase
Klebsiella michiganensis M5al 0.76 BWI76_RS02995 aspartate carbamoyltransferase 0.84 BWI76_RS21025 GMP synthase (glutamine-hydrolyzing)
Serratia liquefaciens MT49 0.76 IAI46_02275 aspartate carbamoyltransferase 0.84 IAI46_19205 glutamine-hydrolyzing GMP synthase
Escherichia coli HS(pFamp)R (ATCC 700891) 0.75 OHPLBJKB_03789 Aspartate carbamoyltransferase catalytic subunit 0.84 OHPLBJKB_01202 GMP synthase [glutamine-hydrolyzing]
Escherichia coli BW25113 0.75 b4245 pyrB aspartate carbamoyltransferase catalytic subunit (NCBI) 0.84 b2507 guaA bifunctional GMP synthase/glutamine amidotransferase protein (NCBI)
Escherichia coli ECOR38 0.75 HEPCGN_10060 pyrB aspartate carbamoyltransferase 0.84 HEPCGN_20905 guaA glutamine-hydrolyzing GMP synthase low > 88
Escherichia coli ECRC100 0.75 OKFHMN_11865 pyrB aspartate carbamoyltransferase 0.84 OKFHMN_21765 guaA glutamine-hydrolyzing GMP synthase
Escherichia coli ECRC101 0.75 MCAODC_02370 pyrB aspartate carbamoyltransferase 0.84 MCAODC_12295 guaA glutamine-hydrolyzing GMP synthase low > 87
Escherichia coli ECRC102 0.75 NIAGMN_09715 pyrB aspartate carbamoyltransferase 0.84 NIAGMN_19535 guaA glutamine-hydrolyzing GMP synthase low > 80
Escherichia fergusonii Becca 0.75 EFB2_04288 Aspartate carbamoyltransferase catalytic subunit 0.84 EFB2_01386 GMP synthase [glutamine-hydrolyzing]
Escherichia coli ECRC99 0.75 KEDOAH_16290 pyrB aspartate carbamoyltransferase 0.84 KEDOAH_06455 guaA glutamine-hydrolyzing GMP synthase
Escherichia coli ECRC62 0.75 BNILDI_07385 pyrB aspartate carbamoyltransferase 0.83 BNILDI_12215 guaA glutamine-hydrolyzing GMP synthase 0.91 19
Escherichia coli Nissle 1917 0.75 ECOLIN_RS24625 aspartate carbamoyltransferase 0.84 ECOLIN_RS14235 glutamine-hydrolyzing GMP synthase
Escherichia coli ECRC98 0.75 JDDGAC_15505 pyrB aspartate carbamoyltransferase 0.84 JDDGAC_25440 guaA glutamine-hydrolyzing GMP synthase low > 87
Escherichia coli BL21 0.75 ECD_04113 aspartate carbamoyltransferase, catalytic subunit 0.84 ECD_02399 GMP synthetase (glutamine aminotransferase) low > 61
Dickeya dianthicola ME23 0.75 DZA65_RS01970 aspartate carbamoyltransferase 0.84 DZA65_RS16605 glutamine-hydrolyzing GMP synthase
Erwinia amylovora T8 0.75 OLJFJH_07330 aspartate carbamoyltransferase 0.83 OLJFJH_10505 glutamine-hydrolyzing GMP synthase
Dickeya dianthicola 67-19 0.75 HGI48_RS01900 aspartate carbamoyltransferase 0.85 HGI48_RS15530 glutamine-hydrolyzing GMP synthase low > 71
Dickeya dadantii 3937 0.75 DDA3937_RS01925 aspartate carbamoyltransferase 0.85 DDA3937_RS15415 glutamine-hydrolyzing GMP synthase
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.75 GFF930 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.83 GFF2161 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2)
Pantoea agglomerans CFBP13505 P0401 0.75 PagCFBP13505_RS08955 aspartate carbamoyltransferase 0.84 PagCFBP13505_RS15000 glutamine-hydrolyzing GMP synthase
Erwinia tracheiphila HP pepo 2.2 0.74 IJEDHG_14060 pyrB aspartate carbamoyltransferase 0.82 IJEDHG_02720 guaA glutamine-hydrolyzing GMP synthase
Enterobacter asburiae PDN3 0.74 EX28DRAFT_3446 aspartate carbamoyltransferase (EC 2.1.3.2) 0.84 EX28DRAFT_0140 GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit/GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit
Erwinia tracheiphila SCR3 0.74 LU632_RS20950 pyrB aspartate carbamoyltransferase 0.82 LU632_RS17750 guaA glutamine-hydrolyzing GMP synthase
Pantoea sp. MT58 0.74 IAI47_16860 aspartate carbamoyltransferase 0.84 IAI47_05110 glutamine-hydrolyzing GMP synthase
Enterobacter sp. TBS_079 0.74 MPMX20_00544 Aspartate carbamoyltransferase catalytic subunit 0.84 MPMX20_03381 GMP synthase [glutamine-hydrolyzing]
Rahnella sp. WP5 0.74 EX31_RS12785 aspartate carbamoyltransferase 0.84 EX31_RS20445 glutamine-hydrolyzing GMP synthase
Pectobacterium carotovorum WPP14 0.73 HER17_RS19510 aspartate carbamoyltransferase 0.83 HER17_RS06160 glutamine-hydrolyzing GMP synthase
Bacteroides stercoris CC31F 0.51 HMPREF1181_RS14990 aspartate carbamoyltransferase 0.51 HMPREF1181_RS06130 glutamine-hydrolyzing GMP synthase 0.84 50
Parabacteroides merdae CL09T00C40 0.51 HMPREF1078_RS01350 aspartate carbamoyltransferase 0.51 HMPREF1078_RS10120 glutamine-hydrolyzing GMP synthase
Bacteroides thetaiotaomicron VPI-5482 0.50 BT0742 aspartate carbamoyltransferase catalytic chain (NCBI ptt file) 0.51 BT4265 GMP synthase (glutamine-hydrolyzing) (NCBI ptt file)
Bacteroides ovatus ATCC 8483 0.50 BACOVA_02450 aspartate carbamoyltransferase 0.51 BACOVA_05099 GMP synthase (glutamine-hydrolyzing) domain protein
Phocaeicola dorei CL03T12C01 0.50 ABI39_RS17400 aspartate carbamoyltransferase 0.50 ABI39_RS17985 glutamine-hydrolyzing GMP synthase
Phocaeicola vulgatus CL09T03C04 0.50 HMPREF1058_RS03820 aspartate carbamoyltransferase 0.50 HMPREF1058_RS06040 glutamine-hydrolyzing GMP synthase
Bifidobacterium breve UCC2003 0.42 BBR_RS15425 aspartate carbamoyltransferase 0.48 BBR_RS14405 glutamine-hydrolyzing GMP synthase
Kangiella aquimarina DSM 16071 0.34 B158DRAFT_0021 aspartate carbamoyltransferase (EC 2.1.3.2) 0.78 B158DRAFT_1159 GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit/GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit
Shewanella sp. ANA-3 0.34 Shewana3_3070 aspartate carbamoyltransferase (RefSeq) 0.82 Shewana3_1236 guaA GMP synthase (RefSeq) 0.83 64
Shewanella oneidensis MR-1 0.34 SO1301 pyrB aspartate carbamoyltransferase (NCBI ptt file) 0.83 SO3292 guaA GMP synthase (NCBI ptt file) 0.77 63
Shewanella loihica PV-4 0.33 Shew_1013 aspartate carbamoyltransferase (RefSeq) 0.83 Shew_1298 guaA bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) low > 60
Alteromonas macleodii MIT1002 0.33 MIT1002_00423 Aspartate carbamoyltransferase catalytic chain 0.82 MIT1002_02778 GMP synthase [glutamine-hydrolyzing]
Shewanella amazonensis SB2B 0.33 Sama_0840 aspartate carbamoyltransferase (RefSeq) 0.82 Sama_2358 guaA GMP synthase (RefSeq)
Xanthomonas campestris pv. campestris strain 8004 0.25 Xcc-8004.1722.1 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.72 Xcc-8004.2393.1 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2)
Pseudomonas sp. RS175 0.25 PFR28_04237 Aspartate carbamoyltransferase 0.71 PFR28_00311 GMP synthase [glutamine-hydrolyzing]
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_08135 aspartate carbamoyltransferase catalytic subunit 0.71 AO353_15955 GMP synthase
Pseudomonas sp. DMC3 0.25 GFF204 Aspartate carbamoyltransferase 0.72 GFF4326 GMP synthase [glutamine-hydrolyzing]
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_1016 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.72 PfGW456L13_4817 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2)
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_2347 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.72 Pf1N1B4_839 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2)
Pseudomonas fluorescens FW300-N2C3 0.25 AO356_13450 aspartate carbamoyltransferase catalytic subunit 0.72 AO356_06520 GMP synthase
Pseudomonas fluorescens FW300-N2E2 0.25 Pf6N2E2_4606 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.72 Pf6N2E2_3164 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2)
Pseudomonas stutzeri RCH2 0.24 Psest_0291 aspartate carbamoyltransferase 0.72 Psest_1287 GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit/GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit
Pseudomonas simiae WCS417 0.24 PS417_26700 aspartate carbamoyltransferase catalytic subunit 0.72 PS417_23070 GMP synthase
Lysobacter sp. OAE881 0.24 ABIE51_RS16015 aspartate carbamoyltransferase catalytic subunit 0.73 ABIE51_RS09480 glutamine-hydrolyzing GMP synthase
Pseudomonas orientalis W4I3 0.24 QF045_RS01100 aspartate carbamoyltransferase catalytic subunit 0.72 QF045_RS25295 glutamine-hydrolyzing GMP synthase
Pseudomonas sp. SVBP6 0.24 COO64_RS13575 aspartate carbamoyltransferase catalytic subunit 0.72 COO64_RS04665 guaA glutamine-hydrolyzing GMP synthase
Pseudomonas lactucae CFBP13502 0.24 GEMAOFIL_05477 Aspartate carbamoyltransferase 0.72 GEMAOFIL_04767 GMP synthase [glutamine-hydrolyzing]
Cellulophaga baltica 18 0.24 M666_RS11460 aspartate carbamoyltransferase catalytic subunit 0.52 M666_RS10365 glutamine-hydrolyzing GMP synthase 0.37 66
Marinobacter adhaerens HP15 0.24 HP15_3507 aspartate carbamoyltransferase 0.73 HP15_2050 bifunctional GMP synthase/glutamine amidotransferase protein
Pedobacter sp. GW460-11-11-14-LB5 0.24 CA265_RS14660 aspartate carbamoyltransferase 0.55 CA265_RS15025 GMP synthase (glutamine-hydrolyzing)
Pseudomonas fluorescens SBW25 0.24 PFLU_RS28345 aspartate carbamoyltransferase 0.72 PFLU_RS24730 glutamine-hydrolyzing GMP synthase
Pseudomonas sp. BP01 0.24 JOY50_RS09700 aspartate carbamoyltransferase catalytic subunit 0.72 JOY50_RS11505 guaA glutamine-hydrolyzing GMP synthase
Pseudomonas putida KT2440 0.24 PP_4998 Aspartate carbamoyltransferase 0.72 PP_1032 glutamine-hydrolyzing GMP synthase
Pseudomonas fluorescens SBW25-INTG 0.24 PFLU_RS28345 aspartate carbamoyltransferase 0.72 PFLU_RS24730 glutamine-hydrolyzing GMP synthase
Dyella japonica UNC79MFTsu3.2 0.24 ABZR86_RS10390 aspartate carbamoyltransferase catalytic subunit 0.71 ABZR86_RS05405 glutamine-hydrolyzing GMP synthase
Pseudomonas syringae pv. syringae B728a ΔmexB 0.23 Psyr_0482 aspartate carbamoyltransferase 0.72 Psyr_1262 GMP synthase (glutamine-hydrolyzing)
Rhodanobacter denitrificans FW104-10B01 0.23 LRK54_RS04220 aspartate carbamoyltransferase catalytic subunit 0.70 LRK54_RS00110 glutamine-hydrolyzing GMP synthase
Rhodanobacter denitrificans MT42 0.23 LRK55_RS03990 aspartate carbamoyltransferase catalytic subunit 0.70 LRK55_RS18105 glutamine-hydrolyzing GMP synthase
Pseudomonas syringae pv. syringae B728a 0.23 Psyr_0482 aspartate carbamoyltransferase 0.72 Psyr_1262 GMP synthase (glutamine-hydrolyzing)
Acinetobacter radioresistens SK82 0.23 MPMX26_01099 Aspartate carbamoyltransferase 0.67 MPMX26_00074 GMP synthase [glutamine-hydrolyzing]
Fusobacterium nucleatum SB010 0.23 HUW76_08765 aspartate carbamoyltransferase catalytic subunit 0.58 HUW76_08155 glutamine-hydrolyzing GMP synthase
Mucilaginibacter yixingensis YX-36 DSM 26809 0.23 ABZR88_RS03460 aspartate carbamoyltransferase catalytic subunit 0.54 ABZR88_RS06455 glutamine-hydrolyzing GMP synthase
Dinoroseobacter shibae DFL-12 0.23 Dshi_3091 aspartate carbamoyltransferase (RefSeq) 0.51 Dshi_1587 GMP synthase, large subunit (RefSeq)
Cupriavidus basilensis FW507-4G11 0.23 RR42_RS15860 aspartate carbamoyltransferase catalytic subunit 0.63 RR42_RS11740 GMP synthase
Magnetospirillum magneticum AMB-1 0.23 AMB_RS18300 aspartate carbamoyltransferase 0.56 AMB_RS03760 glutamine-hydrolyzing GMP synthase
Pseudomonas sp. S08-1 0.23 OH686_10940 aspartate carbamoyltransferase 0.72 OH686_17595 GMP synthase [glutamine-hydrolyzing], amidotransferase subunit / GMP synthase [glutamine-hydrolyzing], ATP pyrophosphatase subunit
Rhodanobacter sp000427505 FW510-R12 0.23 LRK53_RS05705 aspartate carbamoyltransferase catalytic subunit 0.69 LRK53_RS11155 glutamine-hydrolyzing GMP synthase
Pseudomonas aeruginosa PUPa3 0.23 DQ20_RS37310 aspartate carbamoyltransferase catalytic subunit 0.72 DQ20_RS43020 guaA;go_function=GMP glutamine-hydrolyzing GMP synthase
Acinetobacter baumannii LAC-4 0.23 RR41_RS10085 aspartate carbamoyltransferase catalytic subunit 0.68 RR41_RS18260 glutamine-hydrolyzing GMP synthase
Methylophilus sp. DMC18 0.23 GFF868 Aspartate carbamoyltransferase 0.64 GFF1137 GMP synthase [glutamine-hydrolyzing]
Pseudomonas segetis P6 0.23 MPMX49_00620 Aspartate carbamoyltransferase 0.71 MPMX49_01541 GMP synthase [glutamine-hydrolyzing]
Echinicola vietnamensis KMM 6221, DSM 17526 0.23 Echvi_4661 aspartate carbamoyltransferase 0.52 Echvi_0152 GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit/GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit
Pseudomonas aeruginosa MRSN321 0.23 DY961_RS21990 aspartate carbamoyltransferase catalytic subunit 0.72 DY961_RS14080 guaA;go_function=GMP glutamine-hydrolyzing GMP synthase
Pseudomonas aeruginosa PA14 0.23 IKLFDK_23410 aspartate carbamoyltransferase catalytic subunit 0.72 IKLFDK_19410 glutamine-hydrolyzing GMP synthase
Dechlorosoma suillum PS 0.23 Dsui_0596 aspartate carbamoyltransferase 0.66 Dsui_2670 GMP synthase (glutamine-hydrolyzing)
Ralstonia solanacearum UW163 0.22 UW163_RS00940 aspartate carbamoyltransferase catalytic subunit 0.64 UW163_RS13855 glutamine-hydrolyzing GMP synthase
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS08625 aspartate carbamoyltransferase catalytic subunit 0.64 ABZR87_RS11975 glutamine-hydrolyzing GMP synthase
Ralstonia solanacearum IBSBF1503 0.22 RALBFv3_RS12625 aspartate carbamoyltransferase catalytic subunit 0.64 RALBFv3_RS00525 glutamine-hydrolyzing GMP synthase
Phaeobacter inhibens DSM 17395 0.22 PGA1_c03060 aspartate carbamoyltransferase PyrB 0.52 PGA1_c14610 GMP synthase
Ralstonia solanacearum PSI07 0.22 RPSI07_RS20635 aspartate carbamoyltransferase catalytic subunit 0.63 RPSI07_RS16965 glutamine-hydrolyzing GMP synthase
Azospirillum brasilense Sp245 0.22 AZOBR_RS20575 aspartate carbamoyltransferase 0.57 AZOBR_RS16060 GMP synthase
Ralstonia solanacearum GMI1000 0.22 RS_RS03410 aspartate carbamoyltransferase 0.63 RS_RS07180 glutamine-hydrolyzing GMP synthase
Rhodanobacter sp. FW510-T8 0.22 OKGIIK_11095 pyrB aspartate carbamoyltransferase catalytic subunit 0.70 OKGIIK_07090 guaA glutamine-hydrolyzing GMP synthase
Herbaspirillum seropedicae SmR1 0.22 HSERO_RS02330 aspartate carbamoyltransferase 0.66 HSERO_RS11020 GMP synthase
Azospirillum sp. SherDot2 0.22 MPMX19_01054 Aspartate carbamoyltransferase 0.58 MPMX19_00831 GMP synthase [glutamine-hydrolyzing]
Rhodospirillum rubrum S1H 0.22 Rru_A3190 Aspartate carbamoyltransferase (NCBI) 0.57 Rru_A0355 Glutamine amidotransferase class-I (NCBI)
Pontibacter actiniarum KMM 6156, DSM 19842 0.22 CA264_20465 aspartate carbamoyltransferase 0.53 CA264_08025 GMP synthase (glutamine-hydrolyzing) low > 74
Synechococcus elongatus PCC 7942 0.21 Synpcc7942_0670 pyrB aspartate carbamoyltransferase catalytic subunit 0.52 Synpcc7942_0189 guaA bifunctional GMP synthase/glutamine amidotransferase protein
Hydrogenophaga sp. GW460-11-11-14-LB1 0.21 GFF651 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.62 GFF4357 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2)
Sphingobium sp. HT1-2 0.21 GFF1872 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.54 GFF739 GMP synthase [glutamine-hydrolyzing], amidotransferase subunit (EC 6.3.5.2) / GMP synthase [glutamine-hydrolyzing], ATP pyrophosphatase subunit (EC 6.3.5.2)
Mycobacterium tuberculosis H37Rv 0.21 Rv1380 Probable aspartate carbamoyltransferase PyrB (ATCase) (aspartate transcarbamylase) 0.46 Rv3396c Probable GMP synthase [glutamine-hydrolyzing] GuaA (glutamine amidotransferase) (GMP synthetase)
Acidovorax sp. GW101-3H11 0.21 Ac3H11_3978 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.60 Ac3H11_2854 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2)
Sinorhizobium meliloti 1021 0.21 SMc01360 aspartate carbamoyltransferase catalytic subunit 0.55 SMc00394 GMP synthase
Synechocystis sp000284455 PCC 6803 0.21 SGL_RS10555 aspartate carbamoyltransferase 0.52 SGL_RS13520 glutamine-hydrolyzing GMP synthase
Bosea sp. OAE506 0.20 ABIE41_RS17230 aspartate carbamoyltransferase catalytic subunit 0.55 ABIE41_RS15990 glutamine-hydrolyzing GMP synthase
Agrobacterium fabrum C58 0.20 Atu1308 aspartate carbamoyl transferase catalytic subunit 0.53 Atu0281 GMP synthase
Desulfovibrio vulgaris Hildenborough JW710 0.20 DVU2901 pyrB aspartate carbamoyltransferase (TIGR) 0.54 DVU1043 guaA GMP synthase (TIGR)
Xanthobacter sp. DMC5 0.19 GFF929 Aspartate carbamoyltransferase 0.55 GFF4609 GMP synthase [glutamine-hydrolyzing]
Rhodopseudomonas palustris CGA009 0.19 TX73_016120 aspartate carbamoyltransferase catalytic subunit 0.54 TX73_011370 glutamine-hydrolyzing GMP synthase
Desulfovibrio vulgaris Miyazaki F 0.19 DvMF_1425 pyrB aspartate carbamoyltransferase catalytic subunit (RefSeq) 0.54 DvMF_3125 guaA GMP synthase (RefSeq)

Not shown: 2 genomes with orthologs for CSW01_12725 only; 12 genomes with orthologs for CSW01_03985 only