Conservation of cofitness between BWI76_RS04675 and BWI76_RS11845 in Klebsiella michiganensis M5al

98 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04675 3-isopropylmalate dehydrogenase 1.0 BWI76_RS11845 tryptophan synthase subunit beta 0.90 17
Enterobacter asburiae PDN3 0.95 EX28DRAFT_3669 3-isopropylmalate dehydrogenase 0.97 EX28DRAFT_0933 tryptophan synthase, beta subunit 0.58 69
Enterobacter sp. TBS_079 0.95 MPMX20_00768 3-isopropylmalate dehydrogenase 0.97 MPMX20_02513 Tryptophan synthase beta chain 0.94 9
Escherichia coli Nissle 1917 0.93 ECOLIN_RS00395 3-isopropylmalate dehydrogenase 0.95 ECOLIN_RS07600 tryptophan synthase subunit beta 0.86 23
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.95 GFF2725 Tryptophan synthase beta chain (EC 4.2.1.20) low > 78
Escherichia coli ECRC99 0.93 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase 0.95 KEDOAH_26080 trpB tryptophan synthase subunit beta
Escherichia coli ECRC102 0.93 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase 0.95 NIAGMN_26840 trpB tryptophan synthase subunit beta
Escherichia coli ECOR38 0.93 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase 0.95 HEPCGN_25520 trpB tryptophan synthase subunit beta 0.89 59
Escherichia fergusonii Becca 0.93 EFB2_03972 3-isopropylmalate dehydrogenase 0.95 EFB2_02665 Tryptophan synthase beta chain low > 86
Escherichia coli ECRC98 0.93 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase 0.95 JDDGAC_05215 trpB tryptophan synthase subunit beta 0.93 26
Escherichia coli ECRC101 0.93 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase 0.95 MCAODC_15595 trpB tryptophan synthase subunit beta 0.86 47
Escherichia coli ECRC100 0.93 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase 0.95 OKFHMN_02670 trpB tryptophan synthase subunit beta 0.86 73
Escherichia coli HS(pFamp)R (ATCC 700891) 0.93 OHPLBJKB_03584 3-isopropylmalate dehydrogenase 0.95 OHPLBJKB_02422 Tryptophan synthase beta chain low > 73
Escherichia coli BL21 0.93 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.95 ECD_01235 tryptophan synthase, beta subunit 0.76 50
Escherichia coli ECRC62 0.93 BNILDI_08545 leuA 2-isopropylmalate synthase 0.95 BNILDI_18475 trpB tryptophan synthase subunit beta 0.91 62
Escherichia coli ECOR27 0.93 NOLOHH_03065 leuA 2-isopropylmalate synthase 0.95 NOLOHH_20330 trpB tryptophan synthase subunit beta 0.92 37
Escherichia coli BW25113 0.93 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.95 b1261 trpB tryptophan synthase subunit beta (NCBI) 0.91 37
Dickeya dianthicola 67-19 0.89 HGI48_RS18060 3-isopropylmalate dehydrogenase 0.92 HGI48_RS10465 tryptophan synthase subunit beta low > 71
Dickeya dadantii 3937 0.89 DDA3937_RS18120 3-isopropylmalate dehydrogenase 0.92 DDA3937_RS10465 tryptophan synthase subunit beta low > 74
Dickeya dianthicola ME23 0.89 DZA65_RS19205 3-isopropylmalate dehydrogenase 0.92 DZA65_RS10945 tryptophan synthase subunit beta low > 75
Pectobacterium carotovorum WPP14 0.88 HER17_RS03080 3-isopropylmalate dehydrogenase 0.92 HER17_RS10935 tryptophan synthase subunit beta 0.96 26
Serratia liquefaciens MT49 0.87 IAI46_03350 3-isopropylmalate dehydrogenase 0.93 IAI46_14040 tryptophan synthase subunit beta 0.54 49
Rahnella sp. WP5 0.86 EX31_RS03685 3-isopropylmalate dehydrogenase 0.91 EX31_RS09975 tryptophan synthase subunit beta 0.98 14
Erwinia tracheiphila SCR3 0.82 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase 0.94 LU632_RS12770 trpB tryptophan synthase subunit beta low > 74
Pantoea sp. MT58 0.82 IAI47_16005 3-isopropylmalate dehydrogenase 0.91 IAI47_09170 tryptophan synthase subunit beta 0.95 26
Vibrio cholerae E7946 ATCC 55056 0.77 CSW01_12600 3-isopropylmalate dehydrogenase 0.83 CSW01_05930 tryptophan synthase subunit beta low > 62
Shewanella loihica PV-4 0.68 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.81 Shew_2255 tryptophan synthase subunit beta (RefSeq) 0.93 40
Shewanella sp. ANA-3 0.68 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.81 Shewana3_1516 tryptophan synthase subunit beta (RefSeq) 0.93 23
Shewanella oneidensis MR-1 0.68 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.81 SO3023 trpB tryptophan synthase, beta subunit (NCBI ptt file) 0.92 49
Shewanella amazonensis SB2B 0.68 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) 0.80 Sama_2133 tryptophan synthase subunit beta (RefSeq) 0.89 54
Alteromonas macleodii MIT1002 0.63 MIT1002_00948 3-isopropylmalate dehydrogenase 0.72 MIT1002_01426 Tryptophan synthase beta chain
Desulfovibrio vulgaris Miyazaki F 0.53 DvMF_1794 3-isopropylmalate dehydrogenase (RefSeq) 0.55 DvMF_1741 tryptophan synthase subunit beta (RefSeq) 0.88 25
Desulfovibrio vulgaris Hildenborough JW710 0.52 DVU2985 leuB 3-isopropylmalate dehydrogenase (TIGR) 0.55 DVU0085 trpB-1 tryptophan synthase, beta subunit (TIGR) low > 55
Pseudomonas fluorescens SBW25 0.52 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.54 PFLU_RS00180 tryptophan synthase subunit beta 0.70 13
Pseudomonas fluorescens SBW25-INTG 0.52 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.54 PFLU_RS00180 tryptophan synthase subunit beta 0.84 13
Pseudomonas fluorescens FW300-N1B4 0.52 Pf1N1B4_12 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.54 Pf1N1B4_1831 Tryptophan synthase beta chain (EC 4.2.1.20) 0.90 10
Pseudomonas putida KT2440 0.52 PP_1988 3-isopropylmalate dehydrogenase 0.54 PP_0083 tryptophan synthase beta chain 0.84 25
Pseudomonas fluorescens FW300-N2E3 0.52 AO353_20635 3-isopropylmalate dehydrogenase 0.54 AO353_10710 tryptophan synthase subunit beta 0.89 22
Pseudomonas simiae WCS417 0.51 PS417_18585 3-isopropylmalate dehydrogenase 0.54 PS417_00185 tryptophan synthase subunit beta 0.80 30
Pseudomonas stutzeri RCH2 0.51 Psest_2589 3-isopropylmalate dehydrogenase 0.53 Psest_0063 tryptophan synthase, beta subunit 0.67 37
Marinobacter adhaerens HP15 0.51 HP15_1832 3-isopropylmalate dehydrogenase 0.54 HP15_1827 tryptophan synthase, beta subunit
Pseudomonas fluorescens FW300-N2E2 0.51 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.53 Pf6N2E2_4048 Tryptophan synthase beta chain (EC 4.2.1.20) 0.93 10
Pseudomonas fluorescens FW300-N2C3 0.51 AO356_21415 3-isopropylmalate dehydrogenase 0.53 AO356_10915 tryptophan synthase subunit beta 0.92 20
Dechlorosoma suillum PS 0.51 Dsui_3198 3-isopropylmalate dehydrogenase 0.53 Dsui_3192 tryptophan synthase, beta subunit
Pseudomonas fluorescens GW456-L13 0.51 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.53 PfGW456L13_566 Tryptophan synthase beta chain (EC 4.2.1.20) 0.85 40
Pseudomonas sp. RS175 0.50 PFR28_02821 3-isopropylmalate dehydrogenase 0.54 PFR28_04715 Tryptophan synthase beta chain
Acinetobacter radioresistens SK82 0.50 MPMX26_00348 3-isopropylmalate dehydrogenase 0.51 MPMX26_02617 Tryptophan synthase beta chain 0.94 10
Pseudomonas syringae pv. syringae B728a ΔmexB 0.50 Psyr_1985 3-isopropylmalate dehydrogenase 0.53 Psyr_0034 tryptophan synthase, beta chain low > 86
Pseudomonas syringae pv. syringae B728a 0.50 Psyr_1985 3-isopropylmalate dehydrogenase 0.53 Psyr_0034 tryptophan synthase, beta chain low > 86
Acidovorax sp. GW101-3H11 0.50 Ac3H11_1528 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.52 Ac3H11_1534 Tryptophan synthase beta chain (EC 4.2.1.20) 0.88 20
Pseudomonas sp. S08-1 0.50 OH686_04470 3-isopropylmalate dehydrogenase 0.53 OH686_12425 tryptophan synthase, beta subunit 0.77 26
Kangiella aquimarina DSM 16071 0.50 B158DRAFT_1322 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.61 B158DRAFT_2429 tryptophan synthase, beta subunit low > 40
Castellaniella sp019104865 MT123 0.49 ABCV34_RS04280 3-isopropylmalate dehydrogenase 0.51 ABCV34_RS08435 tryptophan synthase subunit beta
Variovorax sp. OAS795 0.49 ABID97_RS08455 3-isopropylmalate dehydrogenase 0.52 ABID97_RS08430 tryptophan synthase subunit beta
Variovorax sp. SCN45 0.49 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.53 GFF3883 Tryptophan synthase beta chain (EC 4.2.1.20)
Paraburkholderia bryophila 376MFSha3.1 0.49 H281DRAFT_06072 3-isopropylmalate dehydrogenase 0.54 H281DRAFT_06067 tryptophan synthase, beta chain 0.67 12
Burkholderia phytofirmans PsJN 0.49 BPHYT_RS33900 3-isopropylmalate dehydrogenase 0.54 BPHYT_RS33875 tryptophan synthase subunit alpha 0.93 11
Paraburkholderia graminis OAS925 0.48 ABIE53_004804 3-isopropylmalate dehydrogenase 0.54 ABIE53_004809 tryptophan synthase beta chain
Hydrogenophaga sp. GW460-11-11-14-LB1 0.48 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.52 GFF3355 Tryptophan synthase beta chain (EC 4.2.1.20) 0.80 20
Herbaspirillum seropedicae SmR1 0.48 HSERO_RS16500 3-isopropylmalate dehydrogenase 0.49 HSERO_RS16475 tryptophan synthase subunit alpha 0.71 45
Paraburkholderia sabiae LMG 24235 0.48 QEN71_RS17620 3-isopropylmalate dehydrogenase 0.54 QEN71_RS17645 tryptophan synthase subunit beta 0.63 56
Xanthomonas campestris pv. campestris strain 8004 0.48 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.52 Xcc-8004.1964.1 Tryptophan synthase beta chain (EC 4.2.1.20) 0.98 1
Phaeobacter inhibens DSM 17395 0.48 PGA1_c29830 3-isopropylmalate dehydrogenase LeuB 0.55 PGA1_c04870 tryptophan synthase beta chain
Ralstonia solanacearum GMI1000 0.48 RS_RS09990 3-isopropylmalate dehydrogenase 0.54 RS_RS09965 tryptophan synthase subunit beta 0.53 15
Ralstonia solanacearum PSI07 0.48 RPSI07_RS14705 3-isopropylmalate dehydrogenase 0.53 RPSI07_RS14730 tryptophan synthase subunit beta 0.66 14
Ralstonia solanacearum UW163 0.48 UW163_RS11115 3-isopropylmalate dehydrogenase 0.54 UW163_RS11140 tryptophan synthase subunit beta
Ralstonia sp. UNC404CL21Col 0.48 ABZR87_RS14530 3-isopropylmalate dehydrogenase 0.54 ABZR87_RS14500 tryptophan synthase subunit beta 0.93 5
Ralstonia solanacearum IBSBF1503 0.48 RALBFv3_RS02610 3-isopropylmalate dehydrogenase 0.54 RALBFv3_RS02585 tryptophan synthase subunit beta
Cupriavidus basilensis FW507-4G11 0.47 RR42_RS14385 3-isopropylmalate dehydrogenase 0.54 RR42_RS14360 tryptophan synthase subunit alpha 0.61 37
Sphingomonas koreensis DSMZ 15582 0.47 Ga0059261_3190 3-isopropylmalate dehydrogenase 0.55 Ga0059261_0238 tryptophan synthase, beta subunit
Synechococcus elongatus PCC 7942 0.46 Synpcc7942_1505 leuB 3-isopropylmalate dehydrogenase 0.56 Synpcc7942_2143 trpB tryptophan synthase subunit beta
Dinoroseobacter shibae DFL-12 0.45 Dshi_0081 3-isopropylmalate dehydrogenase (RefSeq) 0.53 Dshi_1031 tryptophan synthase, beta subunit (RefSeq)
Azospirillum sp. SherDot2 0.45 MPMX19_00607 3-isopropylmalate dehydrogenase 0.53 MPMX19_02736 Tryptophan synthase beta chain 0.87 13
Azospirillum brasilense Sp245 0.45 AZOBR_RS14130 3-isopropylmalate dehydrogenase 0.53 AZOBR_RS00525 tryptophan synthase subunit beta 0.80 18
Magnetospirillum magneticum AMB-1 0.44 AMB_RS20570 3-isopropylmalate dehydrogenase 0.53 AMB_RS20295 tryptophan synthase subunit beta
Agrobacterium fabrum C58 0.44 Atu2791 3-isopropylmalate dehydrogenase 0.52 Atu0018 tryptophan synthase beta subunit
Pontibacter actiniarum KMM 6156, DSM 19842 0.44 CA264_09445 3-isopropylmalate dehydrogenase 0.51 CA264_05080 tryptophan synthase subunit beta low > 74
Rhizobium sp. OAE497 0.43 ABIE40_RS19050 3-isopropylmalate dehydrogenase 0.53 ABIE40_RS19335 tryptophan synthase subunit beta
Sinorhizobium meliloti 1021 0.43 SMc04405 3-isopropylmalate dehydrogenase 0.54 SMc02766 tryptophan synthase subunit beta 0.71 85
Phocaeicola vulgatus CL09T03C04 0.43 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase 0.47 HMPREF1058_RS07170 tryptophan synthase subunit beta 0.84 5
Phocaeicola dorei CL03T12C01 0.43 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.47 ABI39_RS21045 tryptophan synthase subunit beta 0.73 52
Echinicola vietnamensis KMM 6221, DSM 17526 0.43 Echvi_2062 3-isopropylmalate dehydrogenase 0.48 Echvi_2510 tryptophan synthase, beta subunit
Pedobacter sp. GW460-11-11-14-LB5 0.43 CA265_RS15850 3-isopropylmalate dehydrogenase 0.50 CA265_RS05020 tryptophan synthase subunit beta
Rhodopseudomonas palustris CGA009 0.43 TX73_001175 3-isopropylmalate dehydrogenase 0.52 TX73_000360 tryptophan synthase subunit beta
Bosea sp. OAE506 0.42 ABIE41_RS11860 3-isopropylmalate dehydrogenase 0.53 ABIE41_RS04270 tryptophan synthase subunit beta
Rhodospirillum rubrum S1H 0.42 Rru_A1191 3-isopropylmalate dehydrogenase (NCBI) 0.55 Rru_A3427 Tryptophan synthase, beta chain (NCBI) 0.86 22
Mucilaginibacter yixingensis YX-36 DSM 26809 0.42 ABZR88_RS11605 3-isopropylmalate dehydrogenase 0.51 ABZR88_RS10665 tryptophan synthase subunit beta
Bacteroides thetaiotaomicron VPI-5482 0.42 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.48 BT0533 tryptophan synthase beta chain (NCBI ptt file) 0.77 49
Bacteroides ovatus ATCC 8483 0.42 BACOVA_04600 3-isopropylmalate dehydrogenase 0.47 BACOVA_03779 tryptophan synthase, beta subunit 0.94 32
Parabacteroides merdae CL09T00C40 0.42 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase 0.48 HMPREF1078_RS00150 tryptophan synthase subunit beta 0.92 42
Lysobacter sp. OAE881 0.41 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.53 ABIE51_RS08260 tryptophan synthase subunit beta low > 62
Caulobacter crescentus NA1000 Δfur 0.41 CCNA_00193 3-isopropylmalate dehydrogenase 0.52 CCNA_03658 tryptophan synthase beta chain low > 67
Caulobacter crescentus NA1000 0.41 CCNA_00193 3-isopropylmalate dehydrogenase 0.52 CCNA_03658 tryptophan synthase beta chain 0.88 51
Bacteroides stercoris CC31F 0.41 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase 0.48 HMPREF1181_RS15320 tryptophan synthase subunit beta 0.84 46
Brevundimonas sp. GW460-12-10-14-LB2 0.40 A4249_RS09995 3-isopropylmalate dehydrogenase 0.52 A4249_RS11330 tryptophan synthase subunit beta
Rhodanobacter denitrificans MT42 0.40 LRK55_RS09965 3-isopropylmalate dehydrogenase 0.53 LRK55_RS01465 tryptophan synthase subunit beta low > 63
Rhodanobacter denitrificans FW104-10B01 0.39 LRK54_RS10325 3-isopropylmalate dehydrogenase 0.53 LRK54_RS01685 tryptophan synthase subunit beta low > 59
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase 0.53 OKGIIK_04845 trpB tryptophan synthase subunit beta low > 52
Dyella japonica UNC79MFTsu3.2 0.38 ABZR86_RS15950 3-isopropylmalate dehydrogenase 0.54 ABZR86_RS08000 tryptophan synthase subunit beta 0.91 53

Not shown: 0 genomes with orthologs for BWI76_RS04675 only; 3 genomes with orthologs for BWI76_RS11845 only