Conservation of cofitness between BWI76_RS04665 and BWI76_RS11840 in Klebsiella michiganensis M5al

98 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS04665 3-isopropylmalate dehydratase small subunit 1.0 BWI76_RS11840 tryptophan synthase subunit alpha 0.93 18
Enterobacter sp. TBS_079 0.93 MPMX20_00766 3-isopropylmalate dehydratase small subunit 1 0.86 MPMX20_02514 Tryptophan synthase alpha chain 0.92 15
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF167 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.84 GFF2726 Tryptophan synthase alpha chain (EC 4.2.1.20) low > 78
Enterobacter asburiae PDN3 0.92 EX28DRAFT_3667 3-isopropylmalate dehydratase, small subunit 0.86 EX28DRAFT_0932 tryptophan synthase, alpha chain (EC 4.2.1.20) low > 76
Escherichia coli ECOR27 0.88 NOLOHH_03075 leuD 3-isopropylmalate dehydratase small subunit 0.85 NOLOHH_20335 trpA tryptophan synthase subunit alpha 0.86 41
Escherichia coli ECRC62 0.88 BNILDI_08535 leuD 3-isopropylmalate dehydratase small subunit 0.85 BNILDI_18480 trpA tryptophan synthase subunit alpha 0.88 60
Escherichia coli BL21 0.88 ECD_00073 3-isopropylmalate dehydratase small subunit 0.85 ECD_01234 tryptophan synthase, alpha subunit low > 61
Escherichia coli BW25113 0.88 b0071 leuD isopropylmalate isomerase small subunit (NCBI) 0.85 b1260 trpA tryptophan synthase subunit alpha (NCBI) 0.91 34
Escherichia coli HS(pFamp)R (ATCC 700891) 0.88 OHPLBJKB_03586 3-isopropylmalate dehydratase small subunit 0.85 OHPLBJKB_02423 Tryptophan synthase alpha chain low > 73
Escherichia coli ECOR38 0.88 HEPCGN_08710 leuD 3-isopropylmalate dehydratase small subunit 0.84 HEPCGN_25515 trpA tryptophan synthase subunit alpha 0.84 64
Escherichia fergusonii Becca 0.88 EFB2_03974 3-isopropylmalate dehydratase small subunit 0.84 EFB2_02666 Tryptophan synthase alpha chain low > 86
Escherichia coli Nissle 1917 0.88 ECOLIN_RS00385 3-isopropylmalate dehydratase small subunit 0.85 ECOLIN_RS07595 tryptophan synthase subunit alpha
Escherichia coli ECRC101 0.87 MCAODC_01245 leuD 3-isopropylmalate dehydratase small subunit 0.85 MCAODC_15590 trpA tryptophan synthase subunit alpha 0.84 49
Escherichia coli ECRC102 0.87 NIAGMN_08580 leuD 3-isopropylmalate dehydratase small subunit 0.85 NIAGMN_26845 trpA tryptophan synthase subunit alpha
Escherichia coli ECRC98 0.87 JDDGAC_14325 leuD 3-isopropylmalate dehydratase small subunit 0.85 JDDGAC_05220 trpA tryptophan synthase subunit alpha 0.79 51
Escherichia coli ECRC99 0.87 KEDOAH_17425 leuD 3-isopropylmalate dehydratase small subunit 0.85 KEDOAH_26075 trpA tryptophan synthase subunit alpha
Escherichia coli ECRC100 0.87 OKFHMN_10730 leuD 3-isopropylmalate dehydratase small subunit 0.85 OKFHMN_02675 trpA tryptophan synthase subunit alpha low > 80
Rahnella sp. WP5 0.84 EX31_RS03695 3-isopropylmalate dehydratase small subunit 0.72 EX31_RS09980 tryptophan synthase subunit alpha 0.95 27
Serratia liquefaciens MT49 0.84 IAI46_03340 3-isopropylmalate dehydratase small subunit 0.78 IAI46_14045 tryptophan synthase subunit alpha low > 86
Pectobacterium carotovorum WPP14 0.84 HER17_RS03070 3-isopropylmalate dehydratase small subunit 0.79 HER17_RS10940 tryptophan synthase subunit alpha 0.97 13
Dickeya dianthicola ME23 0.84 DZA65_RS19215 3-isopropylmalate dehydratase small subunit 0.77 DZA65_RS10940 tryptophan synthase subunit alpha low > 75
Dickeya dadantii 3937 0.84 DDA3937_RS18130 3-isopropylmalate dehydratase small subunit 0.77 DDA3937_RS10460 tryptophan synthase subunit alpha low > 74
Dickeya dianthicola 67-19 0.83 HGI48_RS18070 3-isopropylmalate dehydratase small subunit 0.77 HGI48_RS10460 tryptophan synthase subunit alpha low > 71
Pantoea sp. MT58 0.83 IAI47_16015 3-isopropylmalate dehydratase small subunit 0.74 IAI47_09165 tryptophan synthase subunit alpha 0.93 29
Erwinia tracheiphila SCR3 0.74 LU632_RS02865 leuD 3-isopropylmalate dehydratase small subunit 0.72 LU632_RS12775 trpA tryptophan synthase subunit alpha low > 74
Vibrio cholerae E7946 ATCC 55056 0.73 CSW01_12610 3-isopropylmalate dehydratase small subunit 0.62 CSW01_05925 tryptophan synthase subunit alpha 0.74 6
Shewanella loihica PV-4 0.63 Shew_3469 isopropylmalate isomerase small subunit (RefSeq) 0.62 Shew_2256 trpA tryptophan synthase subunit alpha (RefSeq) 0.93 37
Pseudomonas stutzeri RCH2 0.63 Psest_2590 3-isopropylmalate dehydratase, small subunit 0.29 Psest_0062 tryptophan synthase, alpha subunit 0.65 34
Pseudomonas sp. S08-1 0.62 OH686_04475 3-isopropylmalate dehydratase small subunit 0.28 OH686_12430 tryptophan synthase, alpha subunit 0.72 22
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3947 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.28 PfGW456L13_565 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.86 39
Pseudomonas fluorescens FW300-N1B4 0.62 Pf1N1B4_14 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.27 Pf1N1B4_1830 Tryptophan synthase alpha chain (EC 4.2.1.20)
Pseudomonas sp. RS175 0.62 PFR28_02823 3-isopropylmalate dehydratase small subunit 1 0.27 PFR28_04716 Tryptophan synthase alpha chain
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_20625 3-isopropylmalate dehydratase 0.28 AO353_10705 tryptophan synthase subunit alpha 0.80 35
Alteromonas macleodii MIT1002 0.62 MIT1002_00946 3-isopropylmalate dehydratase small subunit 1 0.54 MIT1002_01425 Tryptophan synthase alpha chain
Pseudomonas putida KT2440 0.62 PP_1986 3-isopropylmalate dehydratase small subunit 0.30 PP_0082 tryptophan synthase alpha chain 0.83 13
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_64 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.28 Pf6N2E2_4047 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.87 16
Pseudomonas fluorescens SBW25 0.61 PFLU_RS20575 3-isopropylmalate dehydratase small subunit 0.29 PFLU_RS00175 tryptophan synthase subunit alpha 0.61 11
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS20575 3-isopropylmalate dehydratase small subunit 0.29 PFLU_RS00175 tryptophan synthase subunit alpha 0.78 17
Pseudomonas fluorescens FW300-N2C3 0.61 AO356_21405 3-isopropylmalate dehydratase 0.28 AO356_10910 tryptophan synthase subunit alpha 0.92 16
Xanthomonas campestris pv. campestris strain 8004 0.61 Xcc-8004.1050.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.25 Xcc-8004.1967.1 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.89 8
Pseudomonas syringae pv. syringae B728a ΔmexB 0.61 Psyr_1984 3-isopropylmalate dehydratase, small subunit 0.29 Psyr_0033 tryptophan synthase, alpha chain low > 86
Pseudomonas syringae pv. syringae B728a 0.61 Psyr_1984 3-isopropylmalate dehydratase, small subunit 0.29 Psyr_0033 tryptophan synthase, alpha chain 0.65 49
Pseudomonas simiae WCS417 0.61 PS417_18595 3-isopropylmalate dehydratase 0.29 PS417_00180 tryptophan synthase subunit alpha 0.60 44
Shewanella amazonensis SB2B 0.60 Sama_0338 leuD isopropylmalate isomerase small subunit (RefSeq) 0.57 Sama_2134 trpA tryptophan synthase subunit alpha (RefSeq) 0.89 52
Variovorax sp. SCN45 0.60 GFF3889 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.26 GFF3882 Tryptophan synthase alpha chain (EC 4.2.1.20)
Shewanella oneidensis MR-1 0.60 SO4233 leuD 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) 0.62 SO3024 trpA tryptophan synthase, alpha subunit (NCBI ptt file) 0.91 50
Ralstonia sp. UNC404CL21Col 0.60 ABZR87_RS14535 3-isopropylmalate dehydratase small subunit 0.28 ABZR87_RS14490 tryptophan synthase subunit alpha 0.90 3
Cupriavidus basilensis FW507-4G11 0.59 RR42_RS14390 3-isopropylmalate dehydratase 0.29 RR42_RS14350 tryptophan synthase alpha chain
Ralstonia solanacearum PSI07 0.59 RPSI07_RS14700 3-isopropylmalate dehydratase small subunit 0.29 RPSI07_RS14740 tryptophan synthase subunit alpha
Ralstonia solanacearum GMI1000 0.59 RS_RS09995 3-isopropylmalate dehydratase small subunit 0.29 RS_RS09955 tryptophan synthase subunit alpha
Shewanella sp. ANA-3 0.59 Shewana3_3758 leuD isopropylmalate isomerase small subunit (RefSeq) 0.61 Shewana3_1515 trpA tryptophan synthase subunit alpha (RefSeq) 0.91 39
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_06073 3-isopropylmalate dehydratase, small subunit 0.27 H281DRAFT_06065 tryptophan synthase, alpha chain low > 103
Kangiella aquimarina DSM 16071 0.59 B158DRAFT_1320 3-isopropylmalate dehydratase, small subunit 0.48 B158DRAFT_2430 tryptophan synthase, alpha chain (EC 4.2.1.20) low > 40
Paraburkholderia sabiae LMG 24235 0.58 QEN71_RS17615 3-isopropylmalate dehydratase small subunit 0.28 QEN71_RS17655 tryptophan synthase subunit alpha 0.71 49
Variovorax sp. OAS795 0.58 ABID97_RS08460 3-isopropylmalate dehydratase small subunit 0.25 ABID97_RS08425 tryptophan synthase subunit alpha
Hydrogenophaga sp. GW460-11-11-14-LB1 0.58 GFF3361 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.27 GFF3354 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.92 3
Ralstonia solanacearum UW163 0.58 UW163_RS11110 3-isopropylmalate dehydratase small subunit 0.29 UW163_RS11150 tryptophan synthase subunit alpha
Ralstonia solanacearum IBSBF1503 0.58 RALBFv3_RS02615 3-isopropylmalate dehydratase small subunit 0.29 RALBFv3_RS02575 tryptophan synthase subunit alpha
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS33905 3-isopropylmalate dehydratase small subunit 0.27 BPHYT_RS33865 tryptophan synthase alpha chain 0.70 23
Herbaspirillum seropedicae SmR1 0.57 HSERO_RS16505 3-isopropylmalate dehydratase small subunit 0.28 HSERO_RS16470 tryptophan synthase subunit alpha 0.66 46
Paraburkholderia graminis OAS925 0.57 ABIE53_004803 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit 0.28 ABIE53_004811 tryptophan synthase alpha chain 0.62 33
Acidovorax sp. GW101-3H11 0.57 Ac3H11_1527 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.26 Ac3H11_1535 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.88 17
Dechlorosoma suillum PS 0.56 Dsui_3199 3-isopropylmalate dehydratase, small subunit 0.33 Dsui_3191 tryptophan synthase, alpha subunit
Marinobacter adhaerens HP15 0.55 HP15_1833 isopropylmalate isomerase small subunit 0.30 HP15_1826 tryptophan synthase, alpha subunit
Castellaniella sp019104865 MT123 0.55 ABCV34_RS04285 3-isopropylmalate dehydratase small subunit 0.26 ABCV34_RS08430 tryptophan synthase subunit alpha
Acinetobacter radioresistens SK82 0.55 MPMX26_00346 3-isopropylmalate dehydratase small subunit 1 0.27 MPMX26_02611 Tryptophan synthase alpha chain
Azospirillum sp. SherDot2 0.51 MPMX19_00606 3-isopropylmalate dehydratase small subunit 1 0.27 MPMX19_02737 Tryptophan synthase alpha chain 0.70 49
Magnetospirillum magneticum AMB-1 0.51 AMB_RS20565 3-isopropylmalate dehydratase small subunit 0.29 AMB_RS20300 tryptophan synthase subunit alpha
Rhodopseudomonas palustris CGA009 0.51 TX73_001215 3-isopropylmalate dehydratase small subunit 0.27 TX73_000365 tryptophan synthase subunit alpha
Dinoroseobacter shibae DFL-12 0.51 Dshi_0083 3-isopropylmalate dehydratase, small subunit (RefSeq) 0.28 Dshi_0952 tryptophan synthase, alpha subunit (RefSeq)
Rhodospirillum rubrum S1H 0.50 Rru_A1190 3-isopropylmalate dehydratase small subunit region (NCBI) 0.23 Rru_A3428 Tryptophan synthase (NCBI) 0.70 23
Azospirillum brasilense Sp245 0.50 AZOBR_RS14135 isopropylmalate isomerase 0.27 AZOBR_RS00520 tryptophan synthase subunit alpha 0.82 19
Agrobacterium fabrum C58 0.49 Atu2790 3-isopropylmalate dehydratase, small subunit 0.23 Atu0019 tryptophan synthase alpha subunit
Phaeobacter inhibens DSM 17395 0.49 PGA1_c29790 3-isopropylmalate dehydratase small subunit 0.29 PGA1_c04930 tryptophan synthase alpha chain
Sinorhizobium meliloti 1021 0.49 SMc03795 isopropylmalate isomerase small subunit 0.25 SMc02765 tryptophan synthase subunit alpha 0.71 79
Rhizobium sp. OAE497 0.48 ABIE40_RS19040 3-isopropylmalate dehydratase small subunit 0.24 ABIE40_RS19340 tryptophan synthase subunit alpha
Bosea sp. OAE506 0.47 ABIE41_RS11640 3-isopropylmalate dehydratase small subunit 0.23 ABIE41_RS03930 tryptophan synthase subunit alpha
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS07370 3-isopropylmalate dehydratase small subunit 0.28 LRK54_RS01680 tryptophan synthase, alpha subunit (EC 4.2.1.20) (from data) 0.29 29
Rhodanobacter denitrificans MT42 0.45 LRK55_RS07100 3-isopropylmalate dehydratase small subunit 0.28 LRK55_RS01460 tryptophan synthase subunit alpha low > 63
Mucilaginibacter yixingensis YX-36 DSM 26809 0.45 ABZR88_RS11600 3-isopropylmalate dehydratase small subunit 0.24 ABZR88_RS10660 tryptophan synthase subunit alpha
Pedobacter sp. GW460-11-11-14-LB5 0.44 CA265_RS15840 3-isopropylmalate dehydratase small subunit 0.25 CA265_RS05025 tryptophan synthase, alpha subunit (EC 4.2.1.20) (from data)
Pontibacter actiniarum KMM 6156, DSM 19842 0.43 CA264_09440 3-isopropylmalate dehydratase small subunit 0.26 CA264_05085 tryptophan synthase subunit alpha 0.33 62
Bifidobacterium breve UCC2003 0.43 BBR_RS19625 3-isopropylmalate dehydratase small subunit 0.24 BBR_RS15810 tryptophan synthase subunit alpha low > 34
Bacteroides stercoris CC31F 0.43 HMPREF1181_RS14140 3-isopropylmalate dehydratase small subunit 0.23 HMPREF1181_RS15350 tryptophan synthase subunit alpha 0.78 46
Phocaeicola dorei CL03T12C01 0.42 ABI39_RS10205 3-isopropylmalate dehydratase small subunit 0.23 ABI39_RS21075 tryptophan synthase subunit alpha 0.70 51
Caulobacter crescentus NA1000 0.42 CCNA_00195 3-isopropylmalate dehydratase small subunit 0.28 CCNA_03657 tryptophan synthase alpha chain 0.90 37
Lysobacter sp. OAE881 0.42 ABIE51_RS17580 3-isopropylmalate dehydratase small subunit 0.30 ABIE51_RS08265 tryptophan synthase subunit alpha 0.80 62
Caulobacter crescentus NA1000 Δfur 0.42 CCNA_00195 3-isopropylmalate dehydratase small subunit 0.28 CCNA_03657 tryptophan synthase alpha chain low > 67
Phocaeicola vulgatus CL09T03C04 0.42 HMPREF1058_RS14555 3-isopropylmalate dehydratase small subunit 0.24 HMPREF1058_RS07200 tryptophan synthase subunit alpha 0.83 12
Parabacteroides merdae CL09T00C40 0.42 HMPREF1078_RS16655 3-isopropylmalate dehydratase small subunit 0.24 HMPREF1078_RS00120 tryptophan synthase subunit alpha 0.87 21
Rhodanobacter sp. FW510-T8 0.40 OKGIIK_13590 leuD 3-isopropylmalate dehydratase small subunit 0.27 OKGIIK_04850 trpA tryptophan synthase subunit alpha low > 52
Dyella japonica UNC79MFTsu3.2 0.40 ABZR86_RS15955 3-isopropylmalate dehydratase small subunit 0.28 ABZR86_RS07995 tryptophan synthase subunit alpha low > 74
Brevundimonas sp. GW460-12-10-14-LB2 0.40 A4249_RS10000 3-isopropylmalate dehydratase small subunit 0.27 A4249_RS11320 tryptophan synthase subunit alpha
Bacteroides ovatus ATCC 8483 0.39 BACOVA_04602 3-isopropylmalate dehydratase, small subunit 0.24 BACOVA_03785 tryptophan synthase, alpha subunit 0.92 31
Bacteroides thetaiotaomicron VPI-5482 0.39 BT1859 3-isopropylmalate dehydratase small subunit (NCBI ptt file) 0.24 BT0527 tryptophan synthase alpha chain (NCBI ptt file) 0.86 16
Mycobacterium tuberculosis H37Rv 0.39 Rv2987c Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) 0.17 Rv1613 Probable tryptophan synthase, alpha subunit TrpA
Echinicola vietnamensis KMM 6221, DSM 17526 0.38 Echvi_2060 3-isopropylmalate dehydratase, small subunit 0.23 Echvi_2511 tryptophan synthase, alpha subunit
Sphingomonas koreensis DSMZ 15582 0.37 Ga0059261_4225 3-isopropylmalate dehydratase, small subunit 0.28 Ga0059261_0239 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.87 54
Synechococcus elongatus PCC 7942 0.27 Synpcc7942_2548 leuD isopropylmalate isomerase small subunit 0.27 Synpcc7942_0411 trpA tryptophan synthase subunit alpha

Not shown: 0 genomes with orthologs for BWI76_RS04665 only; 4 genomes with orthologs for BWI76_RS11840 only