| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Klebsiella michiganensis M5al | 1.0 | BWI76_RS00805 | | 5,10-methylenetetrahydrofolate reductase | 1.0 | BWI76_RS00975 | | dihydroxy-acid dehydratase | 0.89 | 16 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.96 | GFF2329 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.96 | GFF2901 | | Dihydroxy-acid dehydratase (EC 4.2.1.9) | low | > 78 |
| Enterobacter asburiae PDN3 | 0.95 | EX28DRAFT_4413 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.97 | EX28DRAFT_4443 | | dihydroxy-acid dehydratase | 0.54 | 53 |
| Enterobacter sp. TBS_079 | 0.95 | MPMX20_04529 | | 5,10-methylenetetrahydrofolate reductase | 0.96 | MPMX20_04499 | | Dihydroxy-acid dehydratase | 0.75 | 5 |
| Escherichia coli BL21 | 0.95 | ECD_03827 | | 5,10-methylenetetrahydrofolate reductase | 0.96 | ECD_03649 | | dihydroxyacid dehydratase | 0.96 | 7 |
| Escherichia coli BW25113 | 0.95 | b3941 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI) | 0.96 | b3771 | ilvD | dihydroxy-acid dehydratase (NCBI) | 0.98 | 1 |
| Escherichia coli ECOR27 | 0.95 | NOLOHH_05810 | metF | methylenetetrahydrofolate reductase | 0.96 | NOLOHH_06775 | ilvD | dihydroxy-acid dehydratase | 0.94 | 34 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.95 | OHPLBJKB_04109 | | 5,10-methylenetetrahydrofolate reductase | 0.96 | OHPLBJKB_04282 | | Dihydroxy-acid dehydratase | low | > 73 |
| Escherichia coli ECRC62 | 0.95 | BNILDI_05725 | metF | methylenetetrahydrofolate reductase | 0.96 | BNILDI_04750 | ilvD | dihydroxy-acid dehydratase | 0.95 | 55 |
| Escherichia coli ECRC99 | 0.95 | KEDOAH_14495 | metF | methylenetetrahydrofolate reductase | 0.96 | KEDOAH_13510 | ilvD | dihydroxy-acid dehydratase | — | — |
| Escherichia coli ECRC98 | 0.95 | JDDGAC_17290 | metF | methylenetetrahydrofolate reductase | 0.96 | JDDGAC_18260 | ilvD | dihydroxy-acid dehydratase | 0.99 | 8 |
| Escherichia coli ECOR38 | 0.95 | HEPCGN_12310 | metF | methylenetetrahydrofolate reductase | 0.96 | HEPCGN_13350 | ilvD | dihydroxy-acid dehydratase | 0.97 | 10 |
| Escherichia coli ECRC100 | 0.95 | OKFHMN_13665 | metF | methylenetetrahydrofolate reductase | 0.96 | OKFHMN_14640 | ilvD | dihydroxy-acid dehydratase | 0.99 | 8 |
| Escherichia coli ECRC101 | 0.95 | MCAODC_04165 | metF | methylenetetrahydrofolate reductase | 0.96 | MCAODC_05145 | ilvD | dihydroxy-acid dehydratase | 0.97 | 9 |
| Escherichia coli ECRC102 | 0.95 | NIAGMN_11420 | metF | methylenetetrahydrofolate reductase | 0.96 | NIAGMN_12395 | ilvD | dihydroxy-acid dehydratase | — | — |
| Escherichia fergusonii Becca | 0.94 | EFB2_04672 | | 5,10-methylenetetrahydrofolate reductase | 0.96 | EFB2_04865 | | Dihydroxy-acid dehydratase | low | > 86 |
| Escherichia coli Nissle 1917 | 0.94 | ECOLIN_RS22760 | | methylenetetrahydrofolate reductase | 0.96 | ECOLIN_RS21665 | | dihydroxy-acid dehydratase | 0.98 | 3 |
| Pantoea sp. MT58 | 0.92 | IAI47_00890 | | methylenetetrahydrofolate reductase | 0.88 | IAI47_01035 | | dihydroxy-acid dehydratase | 0.49 | 36 |
| Serratia liquefaciens MT49 | 0.92 | IAI46_24530 | | methylenetetrahydrofolate reductase | 0.90 | IAI46_24345 | | dihydroxy-acid dehydratase | 0.77 | 18 |
| Dickeya dadantii 3937 | 0.91 | DDA3937_RS00960 | | methylenetetrahydrofolate reductase | 0.90 | DDA3937_RS20155 | | dihydroxy-acid dehydratase | low | > 74 |
| Rahnella sp. WP5 | 0.91 | EX31_RS14205 | | methylenetetrahydrofolate reductase | 0.87 | EX31_RS15005 | | dihydroxy-acid dehydratase | 0.94 | 4 |
| Pectobacterium carotovorum WPP14 | 0.90 | HER17_RS00950 | | methylenetetrahydrofolate reductase | 0.91 | HER17_RS01075 | | dihydroxy-acid dehydratase | low | > 75 |
| Dickeya dianthicola 67-19 | 0.90 | HGI48_RS20415 | | methylenetetrahydrofolate reductase | 0.89 | HGI48_RS20295 | | dihydroxy-acid dehydratase | 0.51 | 24 |
| Dickeya dianthicola ME23 | 0.90 | DZA65_RS21460 | | methylenetetrahydrofolate reductase | 0.90 | DZA65_RS21335 | | dihydroxy-acid dehydratase | 0.79 | 3 |
| Erwinia tracheiphila SCR3 | 0.87 | LU632_RS19630 | metF | methylenetetrahydrofolate reductase | 0.86 | LU632_RS24400 | ilvD | dihydroxy-acid dehydratase | low | > 74 |
| Vibrio cholerae E7946 ATCC 55056 | 0.78 | CSW01_13560 | | methylenetetrahydrofolate reductase | 0.85 | CSW01_00140 | | dihydroxy-acid dehydratase | low | > 62 |
| Shewanella oneidensis MR-1 | 0.76 | SO4054 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | 0.79 | SO4345 | ilvD | dihydroxy-acid dehydratase (NCBI ptt file) | 0.98 | 3 |
| Shewanella amazonensis SB2B | 0.76 | Sama_3169 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.78 | Sama_3279 | | dihydroxy-acid dehydratase (RefSeq) | 0.99 | 2 |
| Shewanella sp. ANA-3 | 0.76 | Shewana3_3612 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.80 | Shewana3_0358 | | dihydroxy-acid dehydratase (RefSeq) | 0.98 | 2 |
| Shewanella loihica PV-4 | 0.75 | Shew_0522 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.78 | Shew_0292 | | dihydroxy-acid dehydratase (RefSeq) | 0.98 | 18 |
| Alteromonas macleodii MIT1002 | 0.70 | MIT1002_03670 | | 5,10-methylenetetrahydrofolate reductase | 0.78 | MIT1002_04041 | | Dihydroxy-acid dehydratase | low | > 70 |
| Azospirillum brasilense Sp245 | 0.55 | AZOBR_RS09540 | | 5 10-methylenetetrahydrofolate reductase | 0.74 | AZOBR_RS15015 | | dihydroxy-acid dehydratase | low | > 97 |
| Magnetospirillum magneticum AMB-1 | 0.55 | AMB_RS02230 | | methylenetetrahydrofolate reductase | 0.72 | AMB_RS12770 | | dihydroxy-acid dehydratase | — | — |
| Azospirillum sp. SherDot2 | 0.55 | MPMX19_00635 | | 5,10-methylenetetrahydrofolate reductase | 0.73 | MPMX19_05356 | | Dihydroxy-acid dehydratase | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.54 | Ga0059261_0992 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.28 | Ga0059261_4216 | | Dihydroxyacid dehydratase/phosphogluconate dehydratase | 0.63 | 52 |
| Bosea sp. OAE506 | 0.52 | ABIE41_RS12475 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.29 | ABIE41_RS15690 | | dihydroxy-acid dehydratase | — | — |
| Rhodospirillum rubrum S1H | 0.52 | Rru_A1530 | | 5,10-methylenetetrahydrofolate reductase (NCBI) | 0.71 | Rru_A1786 | | Dihydroxy-acid dehydratase (NCBI) | 0.96 | 5 |
| Caulobacter crescentus NA1000 Δfur | 0.48 | CCNA_02224 | | methylenetetrahydrofolate reductase | 0.72 | CCNA_03139 | | dihydroxy-acid dehydratase | low | > 67 |
| Caulobacter crescentus NA1000 | 0.48 | CCNA_02224 | | methylenetetrahydrofolate reductase | 0.72 | CCNA_03139 | | dihydroxy-acid dehydratase | 0.97 | 5 |
| Rhodopseudomonas palustris CGA009 | 0.46 | TX73_019175 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.74 | TX73_007515 | | dihydroxy-acid dehydratase | — | — |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.46 | A4249_RS07925 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.24 | A4249_RS10030 | | dihydroxy-acid dehydratase | 1.00 | 2 |
| Rhizobium sp. OAE497 | 0.41 | ABIE40_RS11950 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.75 | ABIE40_RS08005 | | dihydroxy-acid dehydratase | 0.86 | 72 |
| Paraburkholderia sabiae LMG 24235 | 0.41 | QEN71_RS28715 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.73 | QEN71_RS21095 | | dihydroxy-acid dehydratase | low | > 153 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.40 | H281DRAFT_05801 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) | 0.74 | H281DRAFT_05312 | | dihydroxyacid dehydratase | low | > 103 |
| Paraburkholderia graminis OAS925 | 0.40 | ABIE53_000061 | | methylenetetrahydrofolate reductase (NADPH) | 0.73 | ABIE53_006513 | | dihydroxy-acid dehydratase | low | > 113 |
| Phaeobacter inhibens DSM 17395 | 0.40 | PGA1_c11700 | | 5,10-methylenetetrahydrofolate reductase MetF | 0.70 | PGA1_c29490 | | dihydroxy-acid dehydratase LivD | 0.91 | 5 |
| Cupriavidus basilensis FW507-4G11 | 0.39 | RR42_RS01385 | | 5,10-methylenetetrahydrofolate reductase | 0.29 | RR42_RS16210 | | dihydroxy-acid dehydratase | — | — |
| Burkholderia phytofirmans PsJN | 0.39 | BPHYT_RS18705 | | 5,10-methylenetetrahydrofolate reductase | 0.73 | BPHYT_RS10100 | | dihydroxy-acid dehydratase | 0.49 | 35 |
| Agrobacterium fabrum C58 | 0.39 | Atu2123 | | methylenetetrahydrofolate reductase | 0.73 | Atu1918 | | dihydroxy-acid dehydratase | — | — |
| Dechlorosoma suillum PS | 0.39 | Dsui_0640 | | 5,10-methylenetetrahydrofolate reductase | 0.73 | Dsui_1122 | | dihydroxy-acid dehydratase | — | — |
| Ralstonia solanacearum GMI1000 | 0.38 | RS_RS00460 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.28 | RS_RS12105 | | dihydroxy-acid dehydratase | — | — |
| Ralstonia solanacearum PSI07 | 0.38 | RPSI07_RS23495 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.29 | RPSI07_RS12840 | | dihydroxy-acid dehydratase | — | — |
| Ralstonia sp. UNC404CL21Col | 0.38 | ABZR87_RS04865 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.74 | ABZR87_RS00240 | | dihydroxy-acid dehydratase | low | > 80 |
| Ralstonia solanacearum UW163 | 0.38 | UW163_RS03705 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.28 | UW163_RS09135 | | dihydroxy-acid dehydratase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.38 | RALBFv3_RS09875 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.28 | RALBFv3_RS04535 | | dihydroxy-acid dehydratase | — | — |
| Pseudomonas sp. RS175 | 0.38 | PFR28_04202 | | 5,10-methylenetetrahydrofolate reductase | 0.75 | PFR28_04278 | | Dihydroxy-acid dehydratase | 0.77 | 7 |
| Pseudomonas sp. S08-1 | 0.37 | OH686_10820 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.74 | OH686_14100 | | dihydroxy-acid dehydratase | 0.78 | 13 |
| Pseudomonas simiae WCS417 | 0.37 | PS417_26510 | | 5,10-methylenetetrahydrofolate reductase | 0.75 | PS417_26890 | | dihydroxy-acid dehydratase | 0.47 | 7 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.37 | Xcc-8004.4336.1 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.71 | Xcc-8004.451.1 | | Dihydroxy-acid dehydratase (EC 4.2.1.9) | low | > 74 |
| Dinoroseobacter shibae DFL-12 | 0.37 | Dshi_2080 | | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.30 | Dshi_0129 | | dihydroxy-acid dehydratase (RefSeq) | — | — |
| Sinorhizobium meliloti 1021 | 0.37 | SMc01843 | | 5,10-methylenetetrahydrofolate reductase | 0.74 | SMc04045 | | dihydroxy-acid dehydratase | 0.98 | 8 |
| Marinobacter adhaerens HP15 | 0.37 | HP15_2917 | | 5,10-methylenetetrahydrofolate reductase-like protein | 0.70 | HP15_595 | | dihydroxy-acid dehydratase | low | > 73 |
| Pseudomonas fluorescens SBW25 | 0.37 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.74 | PFLU_RS28535 | | dihydroxy-acid dehydratase | 0.78 | 5 |
| Pseudomonas fluorescens SBW25-INTG | 0.37 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.74 | PFLU_RS28535 | | dihydroxy-acid dehydratase | 0.78 | 7 |
| Pseudomonas fluorescens FW300-N1B4 | 0.37 | Pf1N1B4_2384 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.75 | Pf1N1B4_2303 | | Dihydroxy-acid dehydratase (EC 4.2.1.9) | 0.91 | 2 |
| Pseudomonas fluorescens FW300-N2E2 | 0.37 | Pf6N2E2_4638 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.74 | Pf6N2E2_4564 | | Dihydroxy-acid dehydratase (EC 4.2.1.9) | 0.73 | 10 |
| Rhodanobacter denitrificans MT42 | 0.37 | LRK55_RS11765 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.25 | LRK55_RS09960 | | dihydroxy-acid dehydratase | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.37 | LRK54_RS12030 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.25 | LRK54_RS10320 | | dihydroxy-acid dehydratase | 0.64 | 33 |
| Pseudomonas fluorescens FW300-N2C3 | 0.36 | AO356_13605 | | 5,10-methylenetetrahydrofolate reductase | 0.74 | AO356_13250 | | dihydroxy-acid dehydratase | 0.96 | 6 |
| Pseudomonas fluorescens FW300-N2E3 | 0.36 | AO353_08015 | | 5,10-methylenetetrahydrofolate reductase | 0.74 | AO353_08345 | | dihydroxy-acid dehydratase | 0.88 | 4 |
| Rhodanobacter sp. FW510-T8 | 0.36 | OKGIIK_11830 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.27 | OKGIIK_13600 | ilvD | dihydroxy-acid dehydratase | low | > 52 |
| Herbaspirillum seropedicae SmR1 | 0.36 | HSERO_RS21425 | | 5,10-methylenetetrahydrofolate reductase | 0.73 | HSERO_RS02650 | | dihydroxy-acid dehydratase | low | > 78 |
| Pseudomonas putida KT2440 | 0.36 | PP_4977 | | 5,10-methylenetetrahydrofolate reductase | 0.73 | PP_5128 | | Dihydroxy-acid dehydratase | 0.48 | 35 |
| Pseudomonas fluorescens GW456-L13 | 0.36 | PfGW456L13_1050 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.74 | PfGW456L13_973 | | Dihydroxy-acid dehydratase (EC 4.2.1.9) | 0.90 | 17 |
| Pseudomonas stutzeri RCH2 | 0.36 | Psest_0313 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.74 | Psest_0234 | | dihydroxy-acid dehydratase | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.36 | ABZR86_RS11570 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.28 | ABZR86_RS15945 | | dihydroxy-acid dehydratase | 0.94 | 32 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.36 | Psyr_0459 | | 5,10-methylenetetrahydrofolate reductase | 0.74 | Psyr_0469 | | dihydroxyacid dehydratase | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.36 | Psyr_0459 | | 5,10-methylenetetrahydrofolate reductase | 0.74 | Psyr_0469 | | dihydroxyacid dehydratase | 0.68 | 5 |
| Lysobacter sp. OAE881 | 0.35 | ABIE51_RS16490 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.27 | ABIE51_RS17540 | | dihydroxy-acid dehydratase | 0.97 | 17 |
| Castellaniella sp019104865 MT123 | 0.35 | ABCV34_RS13550 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.73 | ABCV34_RS14810 | | dihydroxy-acid dehydratase | low | > 48 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.34 | GFF1692 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.64 | GFF2098 | | Dihydroxy-acid dehydratase (EC 4.2.1.9) | — | — |
| Acidovorax sp. GW101-3H11 | 0.34 | Ac3H11_3045 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.73 | Ac3H11_955 | | Dihydroxy-acid dehydratase (EC 4.2.1.9) | 0.80 | 35 |
| Variovorax sp. OAS795 | 0.33 | ABID97_RS25015 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.31 | ABID97_RS17500 | | dihydroxy-acid dehydratase | — | — |
| Variovorax sp. SCN45 | 0.32 | GFF2055 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.31 | GFF471 | | Dihydroxy-acid dehydratase (EC 4.2.1.9) | — | — |
| Acinetobacter radioresistens SK82 | 0.32 | MPMX26_01002 | | 5,10-methylenetetrahydrofolate reductase | 0.29 | MPMX26_03019 | | Dihydroxy-acid dehydratase | low | > 36 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.28 | DVU0997 | metF | 5,10-methylenetetrahydrofolate reductase (TIGR) | 0.39 | DVU3373 | ilvD | dihydroxy-acid dehydratase (TIGR) | 0.86 | 11 |
| Desulfovibrio vulgaris Miyazaki F | 0.27 | DvMF_3034 | | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.38 | DvMF_2034 | | dihydroxy-acid dehydratase (RefSeq) | — | — |
| Bifidobacterium breve UCC2003 | 0.23 | BBR_RS15410 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.56 | BBR_RS17635 | | dihydroxy-acid dehydratase | low | > 34 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.22 | ABZR88_RS20935 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.27 | ABZR88_RS11575 | | dihydroxy-acid dehydratase | low | > 71 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.21 | Echvi_3637 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.28 | Echvi_2055 | | dihydroxy-acid dehydratase | 0.95 | 2 |
| Parabacteroides merdae CL09T00C40 | 0.21 | HMPREF1078_RS07860 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.65 | HMPREF1078_RS16695 | | dihydroxy-acid dehydratase | low | > 61 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.21 | CA265_RS23445 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.26 | CA265_RS15795 | | dihydroxy-acid dehydratase | 0.95 | 14 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.20 | BT3821 | | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | 0.63 | BT2078 | | dihydroxy-acid dehydratase (NCBI ptt file) | low | > 81 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.20 | CA264_16780 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.27 | CA264_06935 | | dihydroxy-acid dehydratase | low | > 74 |
| Phocaeicola dorei CL03T12C01 | 0.19 | ABI39_RS15570 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.64 | ABI39_RS12715 | | dihydroxy-acid dehydratase | low | > 72 |
| Phocaeicola vulgatus CL09T03C04 | 0.19 | HMPREF1058_RS01490 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.64 | HMPREF1058_RS16815 | | dihydroxy-acid dehydratase | low | > 67 |
| Bacteroides stercoris CC31F | 0.18 | HMPREF1181_RS00120 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.64 | HMPREF1181_RS08335 | | dihydroxy-acid dehydratase | low | > 56 |
| Bacteroides ovatus ATCC 8483 | 0.16 | BACOVA_03666 | | methylenetetrahydrofolate reductase (NAD(P)H) | 0.62 | BACOVA_03302 | | dihydroxy-acid dehydratase | low | > 94 |
Not shown: 2 genomes with orthologs for BWI76_RS00805 only; 4 genomes with orthologs for BWI76_RS00975 only