| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Desulfovibrio vulgaris Miyazaki F | 1.0 | DvMF_0450 | | 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) (from data) | 1.0 | DvMF_1792 | | 3-isopropylmalate dehydratase large subunit (RefSeq) | 0.70 | 9 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.74 | DVU1609 | dapB | dihydrodipicolinate reductase (TIGR) | 0.87 | DVU2982 | leuC | 3-isopropylmalate dehydratase / (R)-citramalate isomerase, large subunit LeuC (EC 4.2.1.33; EC 4.2.1.35) (from data) | 0.78 | 3 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.39 | GFF2617 | | 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) | 0.24 | GFF3363 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Variovorax sp. SCN45 | 0.39 | GFF7298 | | 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) | 0.36 | GFF1671 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Acidovorax sp. GW101-3H11 | 0.39 | Ac3H11_686 | | 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) | 0.23 | Ac3H11_1525 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Marinobacter adhaerens HP15 | 0.39 | HP15_3079 | | dihydrodipicolinate reductase | 0.23 | HP15_2599 | | isopropylmalate isomerase large subunit | — | — |
| Ralstonia solanacearum GMI1000 | 0.38 | RS_RS13735 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.22 | RS_RS10000 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.38 | PfGW456L13_5101 | | 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) | 0.29 | PfGW456L13_3592 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.38 | Psyr_4193 | | dihydrodipicolinate reductase | 0.24 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.38 | Psyr_4193 | | dihydrodipicolinate reductase | 0.24 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Shewanella amazonensis SB2B | 0.38 | Sama_2505 | | dihydrodipicolinate reductase (RefSeq) | 0.24 | Sama_0337 | | isopropylmalate isomerase large subunit (RefSeq) | — | — |
| Vibrio cholerae E7946 ATCC 55056 | 0.38 | CSW01_12115 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.22 | CSW01_12605 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas sp. RS175 | 0.38 | PFR28_00075 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.29 | PFR28_01510 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.38 | Pf6N2E2_3366 | | 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) | 0.23 | Pf6N2E2_63 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Pseudomonas stutzeri RCH2 | 0.38 | Psest_0966 | | dihydrodipicolinate reductase | 0.23 | Psest_2591 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Shewanella sp. ANA-3 | 0.38 | Shewana3_0966 | | dihydrodipicolinate reductase (RefSeq) | 0.24 | Shewana3_3759 | | isopropylmalate isomerase large subunit (RefSeq) | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.38 | AO356_07490 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.23 | AO356_21400 | | isopropylmalate isomerase | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.38 | Pf1N1B4_1174 | | 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) | 0.23 | Pf1N1B4_15 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Pseudomonas simiae WCS417 | 0.38 | PS417_24050 | | dihydrodipicolinate reductase | 0.27 | PS417_09410 | | isopropylmalate isomerase | — | — |
| Variovorax sp. OAS795 | 0.38 | ABID97_RS04515 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.26 | ABID97_RS29025 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas fluorescens SBW25 | 0.38 | PFLU_RS25890 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.28 | PFLU_RS10065 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.38 | PFLU_RS25890 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.28 | PFLU_RS10065 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Ralstonia sp. UNC404CL21Col | 0.38 | ABZR87_RS01415 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.27 | ABZR87_RS10345 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.38 | RALBFv3_RS05845 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.22 | RALBFv3_RS02620 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Shewanella oneidensis MR-1 | 0.38 | SO_1140 | dapB | dihydrodipicolinate reductase (RefSeq) | 0.24 | SO4234 | leuC | 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) | — | — |
| Ralstonia solanacearum UW163 | 0.38 | UW163_RS07780 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.22 | UW163_RS11105 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas putida KT2440 | 0.37 | PP_4725 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | PP_1985 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.37 | H281DRAFT_06318 | | dihydrodipicolinate reductase | 0.22 | H281DRAFT_02541 | | 3-isopropylmalate dehydratase, large subunit (EC 4.2.1.33) | — | — |
| Paraburkholderia graminis OAS925 | 0.37 | ABIE53_003529 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | ABIE53_000977 | | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit | — | — |
| Pseudomonas sp. S08-1 | 0.37 | OH686_17070 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.22 | OH686_04480 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Ralstonia solanacearum PSI07 | 0.37 | RPSI07_RS11455 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.23 | RPSI07_RS14695 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Shewanella loihica PV-4 | 0.37 | Shew_2840 | | dihydrodipicolinate reductase (RefSeq) | 0.25 | Shew_3470 | | isopropylmalate isomerase large subunit (RefSeq) | — | — |
| Herbaspirillum seropedicae SmR1 | 0.37 | HSERO_RS03030 | | dihydrodipicolinate reductase | 0.24 | HSERO_RS16515 | | isopropylmalate isomerase | — | — |
| Phaeobacter inhibens DSM 17395 | 0.37 | PGA1_c32920 | | dihydrodipicolinate reductase DapB | 0.25 | PGA1_c29780 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.37 | AO353_05640 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.23 | AO353_20620 | | isopropylmalate isomerase | — | — |
| Burkholderia phytofirmans PsJN | 0.36 | BPHYT_RS16800 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.27 | BPHYT_RS13520 | | isopropylmalate isomerase | — | — |
| Dinoroseobacter shibae DFL-12 | 0.36 | Dshi_3040 | | Dihydrodipicolinate reductase (RefSeq) | 0.27 | Dshi_0695 | | 3-isopropylmalate dehydratase, large subunit (RefSeq) | — | — |
| Rhodopseudomonas palustris CGA009 | 0.36 | TX73_001760 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.27 | TX73_001245 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.35 | QEN71_RS26970 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.22 | QEN71_RS17605 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Castellaniella sp019104865 MT123 | 0.35 | ABCV34_RS07485 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | ABCV34_RS04290 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Dechlorosoma suillum PS | 0.35 | Dsui_3066 | | dihydrodipicolinate reductase | 0.23 | Dsui_3201 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Rahnella sp. WP5 | 0.34 | EX31_RS03840 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.28 | EX31_RS18840 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Pectobacterium carotovorum WPP14 | 0.34 | HER17_RS02890 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.25 | HER17_RS03075 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Acinetobacter radioresistens SK82 | 0.34 | MPMX26_03006 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.21 | MPMX26_00345 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Rhizobium sp. OAE497 | 0.34 | ABIE40_RS00585 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.25 | ABIE40_RS18380 | | 3-isopropylmalate dehydratase large subunit | 0.74 | 19 |
| Methanococcus maripaludis S2 | 0.33 | MMP_RS04790 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.46 | MMP_RS05930 | | 3-isopropylmalate dehydratase large subunit | 0.64 | 11 |
| Dickeya dadantii 3937 | 0.33 | DDA3937_RS18315 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | DDA3937_RS18125 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.33 | GFF216 | | 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) | 0.26 | GFF4223 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Methanococcus maripaludis JJ | 0.33 | MMJJ_RS00345 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.46 | MMJJ_RS08425 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Enterobacter asburiae PDN3 | 0.33 | EX28DRAFT_3636 | | dihydrodipicolinate reductase (EC 1.3.1.26) | 0.25 | EX28DRAFT_3668 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Magnetospirillum magneticum AMB-1 | 0.33 | AMB_RS22745 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.25 | AMB_RS20560 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Kangiella aquimarina DSM 16071 | 0.33 | B158DRAFT_0614 | | dihydrodipicolinate reductase (EC 1.3.1.26) | 0.24 | B158DRAFT_1319 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Dickeya dianthicola 67-19 | 0.33 | HGI48_RS18250 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | HGI48_RS18065 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Dickeya dianthicola ME23 | 0.33 | DZA65_RS19390 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | DZA65_RS19210 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Enterobacter sp. TBS_079 | 0.32 | MPMX20_00738 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.26 | MPMX20_03499 | | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Azospirillum brasilense Sp245 | 0.32 | AZOBR_RS01580 | | dihydrodipicolinate reductase | 0.26 | AZOBR_RS27815 | | isopropylmalate isomerase | — | — |
| Rhodospirillum rubrum S1H | 0.32 | Rru_A0154 | | Dihydrodipicolinate reductase (NCBI) | 0.26 | Rru_A1189 | | 3-isopropylmalate dehydratase large subunit region (NCBI) | — | — |
| Serratia liquefaciens MT49 | 0.32 | IAI46_03185 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | IAI46_03345 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.32 | RR42_RS17550 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.33 | RR42_RS21085 | | 3-isopropylmalate dehydratase | — | — |
| Pantoea sp. MT58 | 0.32 | IAI47_16125 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.23 | IAI47_16010 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Erwinia tracheiphila SCR3 | 0.32 | LU632_RS02760 | dapB | 4-hydroxy-tetrahydrodipicolinate reductase | 0.23 | LU632_RS02870 | leuC | 3-isopropylmalate dehydratase large subunit | — | — |
| Klebsiella michiganensis M5al | 0.32 | BWI76_RS04460 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | BWI76_RS04670 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Escherichia coli ECOR27 | 0.31 | NOLOHH_03285 | dapB | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | NOLOHH_03070 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli BW25113 | 0.31 | b0031 | dapB | dihydrodipicolinate reductase (NCBI) | 0.24 | b0072 | leuC | isopropylmalate isomerase large subunit (NCBI) | — | — |
| Escherichia coli ECRC62 | 0.31 | BNILDI_08315 | dapB | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | BNILDI_08540 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli Nissle 1917 | 0.31 | ECOLIN_RS00160 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | ECOLIN_RS00390 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Escherichia fergusonii Becca | 0.31 | EFB2_04014 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | EFB2_03973 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Escherichia coli ECOR38 | 0.31 | HEPCGN_08940 | dapB | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | HEPCGN_08705 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli BL21 | 0.31 | ECD_00035 | | dihydrodipicolinate reductase | 0.24 | ECD_00074 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.31 | OHPLBJKB_03626 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | OHPLBJKB_03585 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Escherichia coli ECRC102 | 0.31 | NIAGMN_08805 | dapB | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | NIAGMN_08575 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC98 | 0.31 | JDDGAC_14550 | dapB | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | JDDGAC_14320 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC99 | 0.31 | KEDOAH_17200 | dapB | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | KEDOAH_17430 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC100 | 0.31 | OKFHMN_10955 | dapB | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | OKFHMN_10725 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC101 | 0.31 | MCAODC_01470 | dapB | 4-hydroxy-tetrahydrodipicolinate reductase | 0.24 | MCAODC_01240 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Sinorhizobium meliloti 1021 | 0.31 | SMc02837 | | dihydrodipicolinate reductase | 0.26 | SMc03823 | | isopropylmalate isomerase large subunit | — | — |
| Agrobacterium fabrum C58 | 0.30 | Atu0183 | | dihydrodipicolinate reductase | 0.26 | Atu2709 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Azospirillum sp. SherDot2 | 0.30 | MPMX19_05514 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.26 | MPMX19_01998 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.29 | CCNA_03664 | | dihydrodipicolinate reductase | 0.23 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Caulobacter crescentus NA1000 | 0.29 | CCNA_03664 | | dihydrodipicolinate reductase | 0.23 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Rhodanobacter denitrificans MT42 | 0.29 | LRK55_RS17840 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.28 | LRK55_RS09975 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Bosea sp. OAE506 | 0.28 | ABIE41_RS00235 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.25 | ABIE41_RS11660 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.28 | ABZR86_RS05640 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.29 | ABZR86_RS15960 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.28 | LRK54_RS17985 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.28 | LRK54_RS10335 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.27 | Ga0059261_2545 | | dihydrodipicolinate reductase (EC 1.3.1.26) | 0.23 | Ga0059261_4223 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.27 | A4249_RS13645 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.26 | A4249_RS10005 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Rhodanobacter sp. FW510-T8 | 0.27 | OKGIIK_07315 | dapB | 4-hydroxy-tetrahydrodipicolinate reductase | 0.28 | OKGIIK_13585 | leuC | 3-isopropylmalate dehydratase large subunit | — | — |
| Synechococcus elongatus PCC 7942 | 0.20 | Synpcc7942_2136 | dapB | dihydrodipicolinate reductase | 0.23 | Synpcc7942_1898 | leuC | isopropylmalate isomerase large subunit | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.20 | Xcc-8004.2915.1 | | 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) | 0.23 | Xcc-8004.1049.1 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | — | — |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.20 | Echvi_2395 | | 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) (from data) | 0.25 | Echvi_2059 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Parabacteroides merdae CL09T00C40 | 0.18 | HMPREF1078_RS05545 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.23 | HMPREF1078_RS16660 | | 3-isopropylmalate dehydratase large subunit | low | > 61 |
| Mycobacterium tuberculosis H37Rv | 0.17 | Rv2773c | | Dihydrodipicolinate reductase DapB (DHPR) | 0.29 | Rv2988c | | Probable 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) | — | — |
| Bifidobacterium breve UCC2003 | 0.15 | BBR_RS12990 | | 4-hydroxy-tetrahydrodipicolinate reductase | 0.25 | BBR_RS19630 | | 3-isopropylmalate dehydratase large subunit | low | > 34 |