Conservation of cofitness between Shewana3_1236 and Shewana3_3612 in Shewanella sp. ANA-3

99 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Shewanella sp. ANA-3 1.0 Shewana3_1236 guaA GMP synthase (RefSeq) 1.0 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.86 14
Shewanella oneidensis MR-1 0.99 SO3292 guaA GMP synthase (NCBI ptt file) 1.00 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.74 61
Shewanella loihica PV-4 0.94 Shew_1298 guaA bifunctional GMP synthase/glutamine amidotransferase protein (RefSeq) 0.93 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) low > 60
Shewanella amazonensis SB2B 0.93 Sama_2358 guaA GMP synthase (RefSeq) 0.92 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq)
Enterobacter asburiae PDN3 0.86 EX28DRAFT_0140 GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit/GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit 0.75 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form
Enterobacter sp. TBS_079 0.86 MPMX20_03381 GMP synthase [glutamine-hydrolyzing] 0.75 MPMX20_04529 5,10-methylenetetrahydrofolate reductase
Pantoea sp. MT58 0.85 IAI47_05110 glutamine-hydrolyzing GMP synthase 0.74 IAI47_00890 methylenetetrahydrofolate reductase
Klebsiella michiganensis M5al 0.85 BWI76_RS21025 GMP synthase (glutamine-hydrolyzing) 0.76 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase
Serratia liquefaciens MT49 0.85 IAI46_19205 glutamine-hydrolyzing GMP synthase 0.75 IAI46_24530 methylenetetrahydrofolate reductase
Dickeya dadantii 3937 0.85 DDA3937_RS15415 glutamine-hydrolyzing GMP synthase 0.76 DDA3937_RS00960 methylenetetrahydrofolate reductase
Dickeya dianthicola 67-19 0.85 HGI48_RS15530 glutamine-hydrolyzing GMP synthase 0.75 HGI48_RS20415 methylenetetrahydrofolate reductase low > 71
Pectobacterium carotovorum WPP14 0.85 HER17_RS06160 glutamine-hydrolyzing GMP synthase 0.74 HER17_RS00950 methylenetetrahydrofolate reductase
Escherichia fergusonii Becca 0.84 EFB2_01386 GMP synthase [glutamine-hydrolyzing] 0.75 EFB2_04672 5,10-methylenetetrahydrofolate reductase
Escherichia coli ECRC98 0.84 JDDGAC_25440 guaA glutamine-hydrolyzing GMP synthase 0.75 JDDGAC_17290 metF methylenetetrahydrofolate reductase
Escherichia coli Nissle 1917 0.84 ECOLIN_RS14235 glutamine-hydrolyzing GMP synthase 0.75 ECOLIN_RS22760 methylenetetrahydrofolate reductase
Escherichia coli BW25113 0.84 b2507 guaA bifunctional GMP synthase/glutamine amidotransferase protein (NCBI) 0.75 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI)
Escherichia coli HS(pFamp)R (ATCC 700891) 0.84 OHPLBJKB_01202 GMP synthase [glutamine-hydrolyzing] 0.75 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.84 GFF2161 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) 0.76 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Escherichia coli BL21 0.84 ECD_02399 GMP synthetase (glutamine aminotransferase) 0.75 ECD_03827 5,10-methylenetetrahydrofolate reductase low > 60
Rahnella sp. WP5 0.84 EX31_RS20445 glutamine-hydrolyzing GMP synthase 0.75 EX31_RS14205 methylenetetrahydrofolate reductase
Escherichia coli ECRC102 0.84 NIAGMN_19535 guaA glutamine-hydrolyzing GMP synthase 0.75 NIAGMN_11420 metF methylenetetrahydrofolate reductase
Escherichia coli ECOR38 0.84 HEPCGN_20905 guaA glutamine-hydrolyzing GMP synthase 0.75 HEPCGN_12310 metF methylenetetrahydrofolate reductase low > 85
Escherichia coli ECRC101 0.84 OKFHMN_21765 guaA glutamine-hydrolyzing GMP synthase 0.75 OKFHMN_13665 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC101 0.84 MCAODC_12295 guaA glutamine-hydrolyzing GMP synthase 0.75 MCAODC_04165 metF methylenetetrahydrofolate reductase
Escherichia coli ECRC99 0.84 KEDOAH_06455 guaA glutamine-hydrolyzing GMP synthase 0.75 KEDOAH_14495 metF methylenetetrahydrofolate reductase
Escherichia coli ECOR27 0.84 NOLOHH_13415 guaA glutamine-hydrolyzing GMP synthase 0.75 NOLOHH_05810 metF methylenetetrahydrofolate reductase
Dickeya dianthicola ME23 0.84 DZA65_RS16605 glutamine-hydrolyzing GMP synthase 0.74 DZA65_RS21460 methylenetetrahydrofolate reductase
Escherichia coli ECRC62 0.84 BNILDI_12215 guaA glutamine-hydrolyzing GMP synthase 0.75 BNILDI_05725 metF methylenetetrahydrofolate reductase
Alteromonas macleodii MIT1002 0.83 MIT1002_02778 GMP synthase [glutamine-hydrolyzing] 0.67 MIT1002_03670 5,10-methylenetetrahydrofolate reductase
Erwinia tracheiphila SCR3 0.82 LU632_RS17750 guaA glutamine-hydrolyzing GMP synthase 0.74 LU632_RS19630 metF methylenetetrahydrofolate reductase
Vibrio cholerae E7946 ATCC 55056 0.81 CSW01_03985 GMP synthase (glutamine-hydrolyzing) 0.73 CSW01_13560 methylenetetrahydrofolate reductase low > 62
Kangiella aquimarina DSM 16071 0.76 B158DRAFT_1159 GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit/GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit 0.61 B158DRAFT_2461 5,10-methylenetetrahydrofolate reductase (NAD(P)) (EC 1.5.1.20)
Pseudomonas stutzeri RCH2 0.72 Psest_1287 GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit/GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit 0.35 Psest_0313 5,10-methylenetetrahydrofolate reductase, prokaryotic form
Marinobacter adhaerens HP15 0.72 HP15_2050 bifunctional GMP synthase/glutamine amidotransferase protein 0.36 HP15_2917 5,10-methylenetetrahydrofolate reductase-like protein
Pseudomonas fluorescens GW456-L13 0.72 PfGW456L13_4817 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) 0.36 PfGW456L13_1050 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Pseudomonas fluorescens SBW25-INTG 0.72 PFLU_RS24730 glutamine-hydrolyzing GMP synthase 0.36 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H]
Pseudomonas simiae WCS417 0.72 PS417_23070 GMP synthase 0.36 PS417_26510 5,10-methylenetetrahydrofolate reductase
Pseudomonas fluorescens SBW25 0.72 PFLU_RS24730 glutamine-hydrolyzing GMP synthase 0.36 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H]
Pseudomonas fluorescens FW300-N2E2 0.71 Pf6N2E2_3164 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) 0.36 Pf6N2E2_4638 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Pseudomonas fluorescens FW300-N2C3 0.71 AO356_06520 GMP synthase 0.36 AO356_13605 5,10-methylenetetrahydrofolate reductase
Pseudomonas fluorescens FW300-N1B4 0.71 Pf1N1B4_839 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) 0.36 Pf1N1B4_2384 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Pseudomonas fluorescens FW300-N2E3 0.71 AO353_15955 GMP synthase 0.36 AO353_08015 5,10-methylenetetrahydrofolate reductase
Lysobacter sp. OAE881 0.71 ABIE51_RS09480 glutamine-hydrolyzing GMP synthase 0.33 ABIE51_RS16490 methylenetetrahydrofolate reductase [NAD(P)H]
Pseudomonas sp. RS175 0.71 PFR28_00311 GMP synthase [glutamine-hydrolyzing] 0.36 PFR28_04202 5,10-methylenetetrahydrofolate reductase
Pseudomonas syringae pv. syringae B728a 0.71 Psyr_1262 GMP synthase (glutamine-hydrolyzing) 0.35 Psyr_0459 5,10-methylenetetrahydrofolate reductase
Pseudomonas syringae pv. syringae B728a ΔmexB 0.71 Psyr_1262 GMP synthase (glutamine-hydrolyzing) 0.35 Psyr_0459 5,10-methylenetetrahydrofolate reductase
Pseudomonas putida KT2440 0.71 PP_1032 glutamine-hydrolyzing GMP synthase 0.36 PP_4977 5,10-methylenetetrahydrofolate reductase
Xanthomonas campestris pv. campestris strain 8004 0.71 Xcc-8004.2393.1 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) 0.34 Xcc-8004.4336.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Pseudomonas sp. S08-1 0.70 OH686_17595 GMP synthase [glutamine-hydrolyzing], amidotransferase subunit / GMP synthase [glutamine-hydrolyzing], ATP pyrophosphatase subunit 0.35 OH686_10820 methylenetetrahydrofolate reductase [NAD(P)H]
Dyella japonica UNC79MFTsu3.2 0.69 ABZR86_RS05405 glutamine-hydrolyzing GMP synthase 0.35 ABZR86_RS11570 methylenetetrahydrofolate reductase [NAD(P)H]
Rhodanobacter denitrificans MT42 0.68 LRK55_RS18105 glutamine-hydrolyzing GMP synthase 0.34 LRK55_RS11765 methylenetetrahydrofolate reductase [NAD(P)H] low > 63
Rhodanobacter denitrificans FW104-10B01 0.67 LRK54_RS00110 glutamine-hydrolyzing GMP synthase 0.34 LRK54_RS12030 methylenetetrahydrofolate reductase [NAD(P)H]
Rhodanobacter sp. FW510-T8 0.67 OKGIIK_07090 guaA glutamine-hydrolyzing GMP synthase 0.34 OKGIIK_11830 metF methylenetetrahydrofolate reductase [NAD(P)H]
Acinetobacter radioresistens SK82 0.66 MPMX26_00074 GMP synthase [glutamine-hydrolyzing] 0.31 MPMX26_01002 5,10-methylenetetrahydrofolate reductase
Herbaspirillum seropedicae SmR1 0.66 HSERO_RS11020 GMP synthase 0.31 HSERO_RS21425 5,10-methylenetetrahydrofolate reductase
Paraburkholderia sabiae LMG 24235 0.66 QEN71_RS06550 glutamine-hydrolyzing GMP synthase 0.36 QEN71_RS28715 methylenetetrahydrofolate reductase [NAD(P)H]
Burkholderia phytofirmans PsJN 0.64 BPHYT_RS12010 GMP synthase [glutamine-hydrolyzing] 0.34 BPHYT_RS18705 5,10-methylenetetrahydrofolate reductase
Paraburkholderia bryophila 376MFSha3.1 0.64 H281DRAFT_00637 GMP synthase (glutamine-hydrolyzing) 0.35 H281DRAFT_05801 5,10-methylenetetrahydrofolate reductase (NAD(P))
Paraburkholderia graminis OAS925 0.64 ABIE53_002476 GMP synthase (glutamine-hydrolyzing) 0.35 ABIE53_000061 methylenetetrahydrofolate reductase (NADPH)
Dechlorosoma suillum PS 0.63 Dsui_2670 GMP synthase (glutamine-hydrolyzing) 0.34 Dsui_0640 5,10-methylenetetrahydrofolate reductase
Ralstonia solanacearum IBSBF1503 0.63 RALBFv3_RS00525 glutamine-hydrolyzing GMP synthase 0.35 RALBFv3_RS09875 methylenetetrahydrofolate reductase [NAD(P)H]
Ralstonia solanacearum UW163 0.63 UW163_RS13855 glutamine-hydrolyzing GMP synthase 0.35 UW163_RS03705 methylenetetrahydrofolate reductase [NAD(P)H]
Ralstonia sp. UNC404CL21Col 0.62 ABZR87_RS11975 glutamine-hydrolyzing GMP synthase 0.36 ABZR87_RS04865 methylenetetrahydrofolate reductase [NAD(P)H]
Ralstonia solanacearum PSI07 0.62 RPSI07_RS16965 glutamine-hydrolyzing GMP synthase 0.36 RPSI07_RS23495 methylenetetrahydrofolate reductase [NAD(P)H]
Ralstonia solanacearum GMI1000 0.62 RS_RS07180 glutamine-hydrolyzing GMP synthase 0.35 RS_RS00460 methylenetetrahydrofolate reductase [NAD(P)H]
Cupriavidus basilensis FW507-4G11 0.61 RR42_RS11740 GMP synthase 0.37 RR42_RS01385 5,10-methylenetetrahydrofolate reductase
Castellaniella sp019104865 MT123 0.61 ABCV34_RS04890 glutamine-hydrolyzing GMP synthase 0.32 ABCV34_RS13550 methylenetetrahydrofolate reductase [NAD(P)H]
Hydrogenophaga sp. GW460-11-11-14-LB1 0.61 GFF4357 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) 0.33 GFF1692 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Variovorax sp. SCN45 0.59 GFF206 GMP synthase [glutamine-hydrolyzing], amidotransferase subunit (EC 6.3.5.2) / GMP synthase [glutamine-hydrolyzing], ATP pyrophosphatase subunit (EC 6.3.5.2) 0.31 GFF2055 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Acidovorax sp. GW101-3H11 0.59 Ac3H11_2854 GMP synthase [glutamine-hydrolyzing] (EC 6.3.5.2) 0.32 Ac3H11_3045 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Variovorax sp. OAS795 0.58 ABID97_RS16400 glutamine-hydrolyzing GMP synthase 0.31 ABID97_RS25015 methylenetetrahydrofolate reductase [NAD(P)H]
Azospirillum brasilense Sp245 0.57 AZOBR_RS16060 GMP synthase 0.54 AZOBR_RS09540 5 10-methylenetetrahydrofolate reductase
Azospirillum sp. SherDot2 0.56 MPMX19_00831 GMP synthase [glutamine-hydrolyzing] 0.53 MPMX19_00635 5,10-methylenetetrahydrofolate reductase
Fusobacterium nucleatum SB010 0.55 HUW76_08155 glutamine-hydrolyzing GMP synthase 0.23 HUW76_02285 methylenetetrahydrofolate reductase [NAD(P)H]
Brevundimonas sp. GW460-12-10-14-LB2 0.55 A4249_RS03045 glutamine-hydrolyzing GMP synthase 0.46 A4249_RS07925 methylenetetrahydrofolate reductase [NAD(P)H]
Rhodospirillum rubrum S1H 0.55 Rru_A0355 Glutamine amidotransferase class-I (NCBI) 0.51 Rru_A1530 5,10-methylenetetrahydrofolate reductase (NCBI)
Bosea sp. OAE506 0.55 ABIE41_RS15990 glutamine-hydrolyzing GMP synthase 0.50 ABIE41_RS12475 methylenetetrahydrofolate reductase [NAD(P)H]
Magnetospirillum magneticum AMB-1 0.54 AMB_RS03760 glutamine-hydrolyzing GMP synthase 0.53 AMB_RS02230 methylenetetrahydrofolate reductase
Sinorhizobium meliloti 1021 0.53 SMc00394 GMP synthase 0.35 SMc01843 5,10-methylenetetrahydrofolate reductase
Rhodopseudomonas palustris CGA009 0.53 TX73_011370 glutamine-hydrolyzing GMP synthase 0.46 TX73_019175 methylenetetrahydrofolate reductase [NAD(P)H]
Rhizobium sp. OAE497 0.53 ABIE40_RS01255 glutamine-hydrolyzing GMP synthase 0.41 ABIE40_RS11950 methylenetetrahydrofolate reductase [NAD(P)H]
Sphingomonas koreensis DSMZ 15582 0.53 Ga0059261_0317 GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit/GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit 0.53 Ga0059261_0992 5,10-methylenetetrahydrofolate reductase, prokaryotic form
Agrobacterium fabrum C58 0.53 Atu0281 GMP synthase 0.39 Atu2123 methylenetetrahydrofolate reductase
Caulobacter crescentus NA1000 Δfur 0.53 CCNA_01692 GMP synthase GuaA 0.48 CCNA_02224 methylenetetrahydrofolate reductase low > 67
Caulobacter crescentus NA1000 0.53 CCNA_01692 GMP synthase GuaA 0.48 CCNA_02224 methylenetetrahydrofolate reductase
Phaeobacter inhibens DSM 17395 0.53 PGA1_c14610 GMP synthase 0.38 PGA1_c11700 5,10-methylenetetrahydrofolate reductase MetF
Mucilaginibacter yixingensis YX-36 DSM 26809 0.52 ABZR88_RS06455 glutamine-hydrolyzing GMP synthase 0.19 ABZR88_RS20935 methylenetetrahydrofolate reductase [NAD(P)H]
Desulfovibrio vulgaris Miyazaki F 0.52 DvMF_3125 guaA GMP synthase (RefSeq) 0.26 DvMF_3034 5,10-methylenetetrahydrofolate reductase (RefSeq)
Desulfovibrio vulgaris Hildenborough JW710 0.52 DVU1043 guaA GMP synthase (TIGR) 0.27 DVU0997 metF 5,10-methylenetetrahydrofolate reductase (TIGR)
Pedobacter sp. GW460-11-11-14-LB5 0.51 CA265_RS15025 GMP synthase (glutamine-hydrolyzing) 0.20 CA265_RS23445 methylenetetrahydrofolate reductase [NAD(P)H]
Dinoroseobacter shibae DFL-12 0.50 Dshi_1587 GMP synthase, large subunit (RefSeq) 0.38 Dshi_2080 5,10-methylenetetrahydrofolate reductase (RefSeq)
Bacteroides ovatus ATCC 8483 0.50 BACOVA_05099 GMP synthase (glutamine-hydrolyzing) domain protein 0.16 BACOVA_03666 methylenetetrahydrofolate reductase (NAD(P)H) low > 94
Echinicola vietnamensis KMM 6221, DSM 17526 0.50 Echvi_0152 GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit/GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit 0.19 Echvi_3637 5,10-methylenetetrahydrofolate reductase, prokaryotic form
Bacteroides thetaiotaomicron VPI-5482 0.49 BT4265 GMP synthase (glutamine-hydrolyzing) (NCBI ptt file) 0.19 BT3821 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.64 5
Bacteroides stercoris CC31F 0.49 HMPREF1181_RS06130 glutamine-hydrolyzing GMP synthase 0.17 HMPREF1181_RS00120 methylenetetrahydrofolate reductase [NAD(P)H] low > 56
Pontibacter actiniarum KMM 6156, DSM 19842 0.49 CA264_08025 GMP synthase (glutamine-hydrolyzing) 0.20 CA264_16780 methylenetetrahydrofolate reductase [NAD(P)H] low > 74
Parabacteroides merdae CL09T00C40 0.49 HMPREF1078_RS10120 glutamine-hydrolyzing GMP synthase 0.18 HMPREF1078_RS07860 methylenetetrahydrofolate reductase [NAD(P)H] low > 61
Phocaeicola vulgatus CL09T03C04 0.49 HMPREF1058_RS06040 glutamine-hydrolyzing GMP synthase 0.17 HMPREF1058_RS13650 methylenetetrahydrofolate reductase [NAD(P)H] low > 67
Phocaeicola dorei CL03T12C01 0.48 ABI39_RS17985 glutamine-hydrolyzing GMP synthase 0.17 ABI39_RS09240 methylenetetrahydrofolate reductase [NAD(P)H] low > 72
Bifidobacterium breve UCC2003 0.45 BBR_RS14405 glutamine-hydrolyzing GMP synthase 0.23 BBR_RS15410 methylenetetrahydrofolate reductase [NAD(P)H]

Not shown: 2 genomes with orthologs for Shewana3_1236 only; 0 genomes with orthologs for Shewana3_3612 only