Conservation of cofitness between b0071 and b3770 in Escherichia coli BW25113

97 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0071 leuD isopropylmalate isomerase small subunit (NCBI) 1.0 b3770 ilvE branched-chain amino acid aminotransferase (NCBI) 0.97 6
Escherichia coli ECRC62 1.00 BNILDI_08535 leuD 3-isopropylmalate dehydratase small subunit 1.00 BNILDI_04745 ilvE branched-chain-amino-acid transaminase
Escherichia coli BL21 1.00 ECD_00073 3-isopropylmalate dehydratase small subunit 1.00 ECD_03648 branched-chain amino acid aminotransferase 0.42 6
Escherichia coli ECOR27 1.00 NOLOHH_03075 leuD 3-isopropylmalate dehydratase small subunit 1.00 NOLOHH_06780 ilvE branched-chain-amino-acid transaminase low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03586 3-isopropylmalate dehydratase small subunit 1.00 OHPLBJKB_04283 Branched-chain-amino-acid aminotransferase low > 73
Escherichia coli ECRC101 0.99 MCAODC_01245 leuD 3-isopropylmalate dehydratase small subunit 1.00 MCAODC_05150 ilvE branched-chain-amino-acid transaminase
Escherichia coli ECRC98 0.99 JDDGAC_14325 leuD 3-isopropylmalate dehydratase small subunit 1.00 JDDGAC_18265 ilvE branched-chain-amino-acid transaminase
Escherichia coli ECRC101 0.99 OKFHMN_10730 leuD 3-isopropylmalate dehydratase small subunit 1.00 OKFHMN_14645 ilvE branched-chain-amino-acid transaminase
Escherichia coli ECRC99 0.99 KEDOAH_17425 leuD 3-isopropylmalate dehydratase small subunit 1.00 KEDOAH_13505 ilvE branched-chain-amino-acid transaminase
Escherichia coli ECRC102 0.99 NIAGMN_08580 leuD 3-isopropylmalate dehydratase small subunit 1.00 NIAGMN_12400 ilvE branched-chain-amino-acid transaminase
Escherichia coli Nissle 1917 0.99 ECOLIN_RS00385 3-isopropylmalate dehydratase small subunit 1.00 ECOLIN_RS21660 branched-chain-amino-acid transaminase low > 52
Escherichia coli ECOR38 0.99 HEPCGN_08710 leuD 3-isopropylmalate dehydratase small subunit 1.00 HEPCGN_13355 ilvE branched-chain-amino-acid transaminase low > 85
Escherichia fergusonii Becca 0.99 EFB2_03974 3-isopropylmalate dehydratase small subunit 1.00 EFB2_04866 Branched-chain-amino-acid aminotransferase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF167 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.98 GFF2902 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 78
Enterobacter sp. TBS_079 0.90 MPMX20_00766 3-isopropylmalate dehydratase small subunit 1 0.99 MPMX20_04500 Branched-chain-amino-acid aminotransferase low > 85
Enterobacter asburiae PDN3 0.89 EX28DRAFT_3667 3-isopropylmalate dehydratase, small subunit 0.98 EX28DRAFT_4442 branched-chain amino acid aminotransferase, group I 0.85 7
Klebsiella michiganensis M5al 0.89 BWI76_RS04665 3-isopropylmalate dehydratase small subunit 0.97 BWI76_RS00970 branched chain amino acid aminotransferase 0.54 87
Rahnella sp. WP5 0.84 EX31_RS03695 3-isopropylmalate dehydratase small subunit 0.90 EX31_RS15000 branched-chain amino acid transaminase 0.89 64
Dickeya dadantii 3937 0.83 DDA3937_RS18130 3-isopropylmalate dehydratase small subunit 0.91 DDA3937_RS20160 branched-chain-amino-acid transaminase 0.68 43
Dickeya dianthicola ME23 0.83 DZA65_RS19215 3-isopropylmalate dehydratase small subunit 0.91 DZA65_RS21340 branched-chain amino acid transaminase 0.86 10
Dickeya dianthicola 67-19 0.82 HGI48_RS18070 3-isopropylmalate dehydratase small subunit 0.90 HGI48_RS20300 branched-chain-amino-acid transaminase low > 71
Pectobacterium carotovorum WPP14 0.82 HER17_RS03070 3-isopropylmalate dehydratase small subunit 0.90 HER17_RS01070 branched-chain amino acid transaminase low > 75
Serratia liquefaciens MT49 0.81 IAI46_03340 3-isopropylmalate dehydratase small subunit 0.92 IAI46_24350 branched-chain-amino-acid transaminase low > 86
Pantoea sp. MT58 0.79 IAI47_16015 3-isopropylmalate dehydratase small subunit 0.91 IAI47_01030 branched-chain amino acid transaminase 0.96 8
Erwinia tracheiphila SCR3 0.72 LU632_RS02865 leuD 3-isopropylmalate dehydratase small subunit 0.90 LU632_RS24405 branched-chain amino acid transaminase 0.92 4
Vibrio cholerae E7946 ATCC 55056 0.72 CSW01_12610 3-isopropylmalate dehydratase small subunit 0.75 CSW01_00145 branched-chain-amino-acid transaminase low > 62
Pseudomonas fluorescens FW300-N2E3 0.64 AO353_20625 3-isopropylmalate dehydratase 0.20 AO353_26655 branched-chain amino acid aminotransferase low > 101
Pseudomonas fluorescens GW456-L13 0.64 PfGW456L13_3947 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.27 PfGW456L13_4923 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 87
Pseudomonas sp. RS175 0.64 PFR28_02823 3-isopropylmalate dehydratase small subunit 1 0.21 PFR28_02449 putative branched-chain-amino-acid aminotransferase low > 88
Pseudomonas fluorescens SBW25 0.63 PFLU_RS20575 3-isopropylmalate dehydratase small subunit 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase low > 109
Pseudomonas fluorescens FW300-N2E2 0.63 Pf6N2E2_64 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.21 Pf6N2E2_477 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 103
Pseudomonas fluorescens SBW25-INTG 0.63 PFLU_RS20575 3-isopropylmalate dehydratase small subunit 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase low > 109
Pseudomonas fluorescens FW300-N1B4 0.63 Pf1N1B4_14 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.22 Pf1N1B4_4476 Branched-chain amino acid aminotransferase (EC 2.6.1.42)
Pseudomonas putida KT2440 0.63 PP_1986 3-isopropylmalate dehydratase small subunit 0.19 PP_3511 Branched-chain-amino-acid aminotransferase 0.84 9
Pseudomonas sp. S08-1 0.63 OH686_04475 3-isopropylmalate dehydratase small subunit 0.46 OH686_09695 branched-chain amino acid aminotransferase low > 80
Pseudomonas simiae WCS417 0.62 PS417_18595 3-isopropylmalate dehydratase 0.21 PS417_17565 branched-chain amino acid aminotransferase 0.39 86
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_21405 3-isopropylmalate dehydratase 0.21 AO356_22970 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 104
Pseudomonas stutzeri RCH2 0.62 Psest_2590 3-isopropylmalate dehydratase, small subunit 0.46 Psest_0450 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 67
Shewanella loihica PV-4 0.62 Shew_3469 isopropylmalate isomerase small subunit (RefSeq) 0.68 Shew_0291 branched-chain amino acid aminotransferase (RefSeq) 0.93 32
Xanthomonas campestris pv. campestris strain 8004 0.61 Xcc-8004.1050.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.19 Xcc-8004.4199.1 Branched-chain amino acid aminotransferase (EC 2.6.1.42) 0.70 50
Alteromonas macleodii MIT1002 0.60 MIT1002_00946 3-isopropylmalate dehydratase small subunit 1 0.17 MIT1002_00377 Branched-chain-amino-acid aminotransferase 2 0.96 23
Pseudomonas syringae pv. syringae B728a ΔmexB 0.60 Psyr_1984 3-isopropylmalate dehydratase, small subunit 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme low > 86
Pseudomonas syringae pv. syringae B728a 0.60 Psyr_1984 3-isopropylmalate dehydratase, small subunit 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme 0.67 44
Ralstonia solanacearum PSI07 0.59 RPSI07_RS14700 3-isopropylmalate dehydratase small subunit 0.45 RPSI07_RS21175 branched-chain amino acid transaminase
Shewanella sp. ANA-3 0.59 Shewana3_3758 leuD isopropylmalate isomerase small subunit (RefSeq) 0.19 Shewana3_3830 branched-chain amino acid aminotransferase (RefSeq) 0.86 66
Variovorax sp. SCN45 0.59 GFF3889 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.44 GFF5079 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.58 GFF3361 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.46 GFF1835 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 90
Shewanella oneidensis MR-1 0.58 SO4233 leuD 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) 0.19 SO0340 ilvE branched-chain amino acid aminotransferase (NCBI ptt file) 0.86 68
Paraburkholderia bryophila 376MFSha3.1 0.58 H281DRAFT_06073 3-isopropylmalate dehydratase, small subunit 0.43 H281DRAFT_04193 branched chain amino acid aminotransferase apoenzyme low > 103
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS33905 3-isopropylmalate dehydratase small subunit 0.43 BPHYT_RS16285 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 109
Ralstonia solanacearum GMI1000 0.58 RS_RS09995 3-isopropylmalate dehydratase small subunit 0.45 RS_RS02840 branched-chain amino acid transaminase
Herbaspirillum seropedicae SmR1 0.58 HSERO_RS16505 3-isopropylmalate dehydratase small subunit 0.44 HSERO_RS03330 branched-chain amino acid aminotransferase low > 78
Shewanella amazonensis SB2B 0.58 Sama_0338 leuD isopropylmalate isomerase small subunit (RefSeq) 0.19 Sama_3299 branched-chain amino acid aminotransferase (RefSeq) low > 62
Ralstonia sp. UNC404CL21Col 0.58 ABZR87_RS14535 3-isopropylmalate dehydratase small subunit 0.25 ABZR87_RS18540 branched-chain amino acid aminotransferase low > 80
Paraburkholderia sabiae LMG 24235 0.58 QEN71_RS17615 3-isopropylmalate dehydratase small subunit 0.44 QEN71_RS02410 branched-chain amino acid transaminase low > 153
Kangiella aquimarina DSM 16071 0.57 B158DRAFT_1320 3-isopropylmalate dehydratase, small subunit 0.20 B158DRAFT_0078 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase low > 40
Paraburkholderia graminis OAS925 0.57 ABIE53_004803 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit 0.43 ABIE53_003432 branched-chain amino acid aminotransferase low > 113
Ralstonia solanacearum UW163 0.57 UW163_RS11110 3-isopropylmalate dehydratase small subunit 0.46 UW163_RS01455 branched-chain amino acid transaminase
Cupriavidus basilensis FW507-4G11 0.57 RR42_RS14390 3-isopropylmalate dehydratase 0.20 RR42_RS25890 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 128
Ralstonia solanacearum IBSBF1503 0.57 RALBFv3_RS02615 3-isopropylmalate dehydratase small subunit 0.46 RALBFv3_RS12155 branched-chain amino acid transaminase low > 76
Variovorax sp. OAS795 0.57 ABID97_RS08460 3-isopropylmalate dehydratase small subunit 0.44 ABID97_RS03790 branched-chain amino acid transaminase
Acidovorax sp. GW101-3H11 0.56 Ac3H11_1527 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.46 Ac3H11_3369 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 79
Acinetobacter radioresistens SK82 0.55 MPMX26_00346 3-isopropylmalate dehydratase small subunit 1 0.40 MPMX26_00445 Branched-chain-amino-acid aminotransferase 0.98 5
Dechlorosoma suillum PS 0.55 Dsui_3199 3-isopropylmalate dehydratase, small subunit 0.47 Dsui_2030 branched-chain amino acid aminotransferase, group I
Castellaniella sp019104865 MT123 0.54 ABCV34_RS04285 3-isopropylmalate dehydratase small subunit 0.45 ABCV34_RS07930 branched-chain amino acid transaminase low > 48
Marinobacter adhaerens HP15 0.54 HP15_1833 isopropylmalate isomerase small subunit 0.43 HP15_436 branched-chain-amino-acid aminotransferase
Dinoroseobacter shibae DFL-12 0.50 Dshi_0083 3-isopropylmalate dehydratase, small subunit (RefSeq) 0.26 Dshi_3301 branched-chain amino acid aminotransferase (RefSeq)
Rhodopseudomonas palustris CGA009 0.50 TX73_001215 3-isopropylmalate dehydratase small subunit 0.18 TX73_022650 branched-chain amino acid aminotransferase
Azospirillum sp. SherDot2 0.50 MPMX19_00606 3-isopropylmalate dehydratase small subunit 1 0.18 MPMX19_02406 Branched-chain-amino-acid aminotransferase low > 112
Sinorhizobium meliloti 1021 0.49 SMc03795 isopropylmalate isomerase small subunit 0.21 SMc02896 branched-chain amino acid aminotransferase low > 103
Agrobacterium fabrum C58 0.49 Atu2790 3-isopropylmalate dehydratase, small subunit 0.18 Atu0871 branched-chain-amino-acid aminotransferase low > 89
Magnetospirillum magneticum AMB-1 0.48 AMB_RS20565 3-isopropylmalate dehydratase small subunit 0.31 AMB_RS02850 branched-chain amino acid aminotransferase
Rhodospirillum rubrum S1H 0.48 Rru_A1190 3-isopropylmalate dehydratase small subunit region (NCBI) 0.32 Rru_A2223 Branched-chain amino acid aminotransferase I (NCBI) low > 58
Phaeobacter inhibens DSM 17395 0.48 PGA1_c29790 3-isopropylmalate dehydratase small subunit 0.29 PGA1_c34110 branched-chain-amino-acid aminotransferase IlvE 0.76 37
Rhizobium sp. OAE497 0.48 ABIE40_RS19040 3-isopropylmalate dehydratase small subunit 0.19 ABIE40_RS22240 branched-chain amino acid aminotransferase low > 107
Azospirillum brasilense Sp245 0.47 AZOBR_RS14135 isopropylmalate isomerase 0.31 AZOBR_RS16425 branched-chain amino acid aminotransferase low > 97
Bosea sp. OAE506 0.46 ABIE41_RS11640 3-isopropylmalate dehydratase small subunit 0.28 ABIE41_RS11405 branched-chain amino acid aminotransferase
Rhodanobacter denitrificans MT42 0.46 LRK55_RS07100 3-isopropylmalate dehydratase small subunit 0.56 LRK55_RS11755 branched-chain amino acid transaminase low > 63
Rhodanobacter denitrificans FW104-10B01 0.46 LRK54_RS07370 3-isopropylmalate dehydratase small subunit 0.56 LRK54_RS12020 branched-chain amino acid transaminase low > 59
Pedobacter sp. GW460-11-11-14-LB5 0.43 CA265_RS15840 3-isopropylmalate dehydratase small subunit 0.29 CA265_RS15785 branched-chain-amino-acid transaminase low > 88
Pontibacter actiniarum KMM 6156, DSM 19842 0.43 CA264_09440 3-isopropylmalate dehydratase small subunit 0.32 CA264_06940 branched-chain amino acid aminotransferase low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS11600 3-isopropylmalate dehydratase small subunit 0.16 ABZR88_RS22095 branched-chain amino acid aminotransferase
Bacteroides stercoris CC31F 0.43 HMPREF1181_RS14140 3-isopropylmalate dehydratase small subunit 0.19 HMPREF1181_RS06865 branched-chain amino acid aminotransferase low > 56
Caulobacter crescentus NA1000 Δfur 0.42 CCNA_00195 3-isopropylmalate dehydratase small subunit 0.31 CCNA_03024 branched-chain amino acid aminotransferase low > 67
Caulobacter crescentus NA1000 0.42 CCNA_00195 3-isopropylmalate dehydratase small subunit 0.31 CCNA_03024 branched-chain amino acid aminotransferase low > 66
Bifidobacterium breve UCC2003 0.42 BBR_RS19625 3-isopropylmalate dehydratase small subunit 0.17 BBR_RS15210 branched-chain amino acid aminotransferase low > 34
Phocaeicola dorei CL03T12C01 0.41 ABI39_RS10205 3-isopropylmalate dehydratase small subunit 0.18 ABI39_RS01415 branched-chain amino acid aminotransferase 0.61 70
Phocaeicola vulgatus CL09T03C04 0.40 HMPREF1058_RS14555 3-isopropylmalate dehydratase small subunit 0.18 HMPREF1058_RS02220 branched-chain amino acid aminotransferase low > 67
Parabacteroides merdae CL09T00C40 0.40 HMPREF1078_RS16655 3-isopropylmalate dehydratase small subunit 0.19 HMPREF1078_RS07855 branched-chain amino acid aminotransferase low > 61
Dyella japonica UNC79MFTsu3.2 0.40 ABZR86_RS15955 3-isopropylmalate dehydratase small subunit 0.56 ABZR86_RS15965 branched-chain amino acid transaminase 0.91 32
Bacteroides ovatus ATCC 8483 0.39 BACOVA_04602 3-isopropylmalate dehydratase, small subunit 0.30 BACOVA_03679 branched-chain-amino-acid transaminase low > 94
Lysobacter sp. OAE881 0.39 ABIE51_RS17580 3-isopropylmalate dehydratase small subunit 0.55 ABIE51_RS16505 branched-chain amino acid transaminase low > 62
Echinicola vietnamensis KMM 6221, DSM 17526 0.38 Echvi_2060 3-isopropylmalate dehydratase, small subunit 0.18 Echvi_2202 branched-chain amino acid aminotransferase, group II
Bacteroides thetaiotaomicron VPI-5482 0.38 BT1859 3-isopropylmalate dehydratase small subunit (NCBI ptt file) 0.19 BT3892 branched-chain amino acid aminotransferase (NCBI ptt file)
Sphingomonas koreensis DSMZ 15582 0.38 Ga0059261_4225 3-isopropylmalate dehydratase, small subunit 0.23 Ga0059261_3811 branched-chain amino acid aminotransferase, group II 0.97 10
Mycobacterium tuberculosis H37Rv 0.37 Rv2987c Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) 0.19 Rv2210c Branched-chain amino acid transaminase IlvE
Brevundimonas sp. GW460-12-10-14-LB2 0.37 A4249_RS10000 3-isopropylmalate dehydratase small subunit 0.27 A4249_RS09820 branched-chain amino acid aminotransferase
Synechococcus elongatus PCC 7942 0.28 Synpcc7942_2548 leuD isopropylmalate isomerase small subunit 0.29 Synpcc7942_1029 ilvE branched-chain amino acid aminotransferase

Not shown: 0 genomes with orthologs for b0071 only; 5 genomes with orthologs for b3770 only