| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BW25113 | 1.0 | b3650 | spoT | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) | 1.0 | b2025 | hisF | imidazole glycerol phosphate synthase subunit HisF (NCBI) | 0.73 | 5 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_00051 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.99 | OHPLBJKB_01675 | | Imidazole glycerol phosphate synthase subunit HisF | low | > 73 |
| Escherichia coli Nissle 1917 | 1.00 | ECOLIN_RS20790 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 1.00 | ECOLIN_RS11970 | | imidazole glycerol phosphate synthase subunit HisF | low | > 52 |
| Escherichia fergusonii Becca | 1.00 | EFB2_00138 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 1.00 | EFB2_01831 | | Imidazole glycerol phosphate synthase subunit HisF | low | > 86 |
| Escherichia coli ECRC101 | 1.00 | MCAODC_06065 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 1.00 | MCAODC_20450 | hisF | Imidazole glycerol phosphate synthase subunit HisF | — | — |
| Escherichia coli ECOR27 | 1.00 | NOLOHH_07435 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.99 | NOLOHH_15805 | hisF | Imidazole glycerol phosphate synthase subunit HisF | — | — |
| Escherichia coli BL21 | 1.00 | ECD_03507 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.99 | ECD_01927 | | imidazole glycerol phosphate synthase, catalytic subunit with HisH | — | — |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_13315 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 1.00 | NIAGMN_22435 | hisF | Imidazole glycerol phosphate synthase subunit HisF | — | — |
| Escherichia coli ECRC101 | 1.00 | OKFHMN_15555 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 1.00 | OKFHMN_24490 | hisF | Imidazole glycerol phosphate synthase subunit HisF | — | — |
| Escherichia coli ECRC62 | 1.00 | BNILDI_04080 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 1.00 | BNILDI_14715 | hisF | Imidazole glycerol phosphate synthase subunit HisF | — | — |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_12590 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 1.00 | KEDOAH_03660 | hisF | Imidazole glycerol phosphate synthase subunit HisF | — | — |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_19180 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 1.00 | JDDGAC_28600 | hisF | Imidazole glycerol phosphate synthase subunit HisF | — | — |
| Escherichia coli ECOR38 | 1.00 | HEPCGN_14375 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.99 | HEPCGN_03195 | hisF | Imidazole glycerol phosphate synthase subunit HisF | low | > 85 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.98 | GFF357 | | 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 | 0.95 | GFF3907 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | low | > 78 |
| Enterobacter asburiae PDN3 | 0.97 | EX28DRAFT_3899 | | (p)ppGpp synthetase, RelA/SpoT family | 0.96 | EX28DRAFT_0534 | | imidazoleglycerol phosphate synthase, cyclase subunit | low | > 76 |
| Enterobacter sp. TBS_079 | 0.97 | MPMX20_00086 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.97 | MPMX20_03007 | | Imidazole glycerol phosphate synthase subunit HisF | 0.42 | 34 |
| Klebsiella michiganensis M5al | 0.96 | BWI76_RS27430 | | (p)ppGpp synthetase | 0.96 | BWI76_RS18950 | | imidazole glycerol phosphate synthase cyclase subunit | low | > 92 |
| Pantoea sp. MT58 | 0.93 | IAI47_00510 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.90 | IAI47_07065 | | imidazole glycerol phosphate synthase subunit HisF | low | > 76 |
| Serratia liquefaciens MT49 | 0.92 | IAI46_24895 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.95 | IAI46_08185 | | imidazole glycerol phosphate synthase subunit HisF | low | > 86 |
| Erwinia tracheiphila SCR3 | 0.92 | LU632_RS22200 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.93 | LU632_RS08920 | hisF | imidazole glycerol phosphate synthase subunit HisF | low | > 74 |
| Rahnella sp. WP5 | 0.91 | EX31_RS15810 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.91 | EX31_RS11465 | | imidazole glycerol phosphate synthase subunit HisF | low | > 89 |
| Dickeya dianthicola ME23 | 0.91 | DZA65_RS22150 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.92 | DZA65_RS10030 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Dickeya dianthicola 67-19 | 0.91 | HGI48_RS21180 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.92 | HGI48_RS09720 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Pectobacterium carotovorum WPP14 | 0.91 | HER17_RS21385 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.91 | HER17_RS12255 | | imidazole glycerol phosphate synthase subunit HisF | low | > 75 |
| Dickeya dadantii 3937 | 0.90 | DDA3937_RS00180 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.93 | DDA3937_RS09710 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Vibrio cholerae E7946 ATCC 55056 | 0.75 | CSW01_13675 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase | 0.87 | CSW01_05775 | | imidazole glycerol phosphate synthase cyclase subunit | low | > 62 |
| Shewanella amazonensis SB2B | 0.71 | Sama_0264 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | 0.77 | Sama_1947 | | imidazole glycerol phosphate synthase subunit HisF (RefSeq) | low | > 62 |
| Shewanella loihica PV-4 | 0.71 | Shew_3499 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | 0.75 | Shew_2203 | | imidazole glycerol phosphate synthase subunit HisF (RefSeq) | low | > 60 |
| Shewanella oneidensis MR-1 | 0.71 | SO0359 | spoT | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (NCBI ptt file) | 0.75 | SO2068 | hisF | hisF protein (cyclase) (NCBI ptt file) | low | > 76 |
| Shewanella sp. ANA-3 | 0.70 | Shewana3_3812 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | 0.75 | Shewana3_1848 | | imidazole glycerol phosphate synthase subunit HisF (RefSeq) | low | > 73 |
| Alteromonas macleodii MIT1002 | 0.62 | MIT1002_00108 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.76 | MIT1002_02638 | | Imidazole glycerol phosphate synthase subunit HisF | low | > 70 |
| Pseudomonas putida KT2440 | 0.56 | PP_5302 | | bifunctional (p)ppGpp synthase/hydrolase | 0.41 | PP_0293 | | Imidazole glycerol phosphate synthase subunit HisF | — | — |
| Kangiella aquimarina DSM 16071 | 0.55 | B158DRAFT_0574 | | (p)ppGpp synthetase, RelA/SpoT family | 0.39 | B158DRAFT_2291 | | imidazoleglycerol phosphate synthase, cyclase subunit | — | — |
| Pseudomonas sp. RS175 | 0.55 | PFR28_04424 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | 0.40 | PFR28_04933 | | Imidazole glycerol phosphate synthase subunit HisF | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.55 | AO353_09280 | | (p)ppGpp synthetase | 0.40 | AO353_12090 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.55 | Pf6N2E2_4361 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.40 | Pf6N2E2_3838 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.55 | Pf1N1B4_2113 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.40 | Pf1N1B4_1623 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.55 | AO356_12480 | | (p)ppGpp synthetase | 0.40 | AO356_09795 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.54 | PfGW456L13_780 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.40 | PfGW456L13_358 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | — | — |
| Pseudomonas sp. S08-1 | 0.54 | OH686_13550 | | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase / GTP pyrophosphokinase , (p)ppGpp synthetase II | 0.42 | OH686_14595 | | Imidazole glycerol phosphate synthase cyclase subunit | 0.62 | 16 |
| Pseudomonas fluorescens SBW25-INTG | 0.54 | PFLU_RS29510 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.40 | PFLU_RS01625 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Pseudomonas fluorescens SBW25 | 0.54 | PFLU_RS29510 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | 0.40 | PFLU_RS01625 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.54 | Psyr_0209 | | RelA/SpoT protein | 0.40 | Psyr_4893 | | imidazole glycerol phosphate synthase subunit hisF | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.54 | Psyr_0209 | | RelA/SpoT protein | 0.40 | Psyr_4893 | | imidazole glycerol phosphate synthase subunit hisF | — | — |
| Pseudomonas simiae WCS417 | 0.54 | PS417_27830 | | (p)ppGpp synthetase | 0.40 | PS417_01580 | | imidazole glycerol phosphate synthase | — | — |
| Pseudomonas stutzeri RCH2 | 0.53 | Psest_3817 | | (p)ppGpp synthetase, RelA/SpoT family | 0.42 | Psest_0156 | | imidazoleglycerol phosphate synthase, cyclase subunit | — | — |
| Marinobacter adhaerens HP15 | 0.51 | HP15_305 | | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.39 | HP15_3009 | | protein containing histidine biosynthesis, HisF domain | — | — |
| Dechlorosoma suillum PS | 0.49 | Dsui_0500 | | (p)ppGpp synthetase, RelA/SpoT family | 0.38 | Dsui_1418 | | imidazoleglycerol phosphate synthase, cyclase subunit | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.48 | ABZR86_RS11850 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.63 | ABZR86_RS06705 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.48 | LRK54_RS11795 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.65 | LRK54_RS01580 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Rhodanobacter denitrificans MT42 | 0.48 | LRK55_RS11520 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.64 | LRK55_RS01360 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Rhodanobacter sp. FW510-T8 | 0.48 | OKGIIK_12100 | spoT | guanosine-3',5'-bis(diphosphate) 3'-diphosphatase | 0.64 | OKGIIK_04975 | hisF | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.46 | RALBFv3_RS03315 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.43 | RALBFv3_RS06815 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Burkholderia phytofirmans PsJN | 0.46 | BPHYT_RS15305 | | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.41 | BPHYT_RS17680 | | imidazole glycerol phosphate synthase subunit HisF | low | > 109 |
| Ralstonia solanacearum UW163 | 0.46 | UW163_RS10410 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.43 | UW163_RS06800 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Ralstonia sp. UNC404CL21Col | 0.46 | ABZR87_RS15225 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.42 | ABZR87_RS02470 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Ralstonia solanacearum PSI07 | 0.46 | RPSI07_RS13870 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.42 | RPSI07_RS10420 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Lysobacter sp. OAE881 | 0.46 | ABIE51_RS17265 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.65 | ABIE51_RS13300 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Herbaspirillum seropedicae SmR1 | 0.46 | HSERO_RS10635 | | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.39 | HSERO_RS20315 | | imidazole glycerol phosphate synthase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.46 | RR42_RS04920 | | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.42 | RR42_RS18885 | | imidazole glycerol phosphate synthase | — | — |
| Castellaniella sp019104865 MT123 | 0.45 | ABCV34_RS03095 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.37 | ABCV34_RS11250 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Ralstonia solanacearum GMI1000 | 0.45 | RS_RS10800 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.42 | RS_RS14760 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.45 | H281DRAFT_04004 | | (p)ppGpp synthetase I, SpoT/RelA | 0.41 | H281DRAFT_05659 | | imidazole glycerol phosphate synthase subunit hisF | — | — |
| Paraburkholderia graminis OAS925 | 0.45 | ABIE53_003230 | | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.41 | ABIE53_003695 | | cyclase | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.45 | QEN71_RS03665 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.40 | QEN71_RS27835 | | imidazole glycerol phosphate synthase subunit HisF | low | > 153 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.45 | Xcc-8004.1215.1 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.63 | Xcc-8004.2943.1 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | — | — |
| Acidovorax sp. GW101-3H11 | 0.41 | Ac3H11_3664 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.34 | Ac3H11_4733 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | — | — |
| Variovorax sp. SCN45 | 0.41 | GFF2375 | | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II | 0.39 | GFF5357 | | Imidazole glycerol phosphate synthase cyclase subunit | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.41 | GFF1034 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | 0.38 | GFF1309 | | Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) | — | — |
| Variovorax sp. OAS795 | 0.40 | ABID97_RS23670 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.41 | ABID97_RS23105 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Azospirillum brasilense Sp245 | 0.38 | AZOBR_RS22045 | | GTP pyrophosphokinase | 0.40 | AZOBR_RS01685 | | imidazole glycerol phosphate synthase | low | > 97 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.38 | DVU2083 | relA | GTP pyrophosphokinase (TIGR) | 0.37 | DVU0286 | hisF | imidazoleglycerol phosphate synthase, cyclase subunit (TIGR) | 0.56 | 23 |
| Desulfovibrio vulgaris Miyazaki F | 0.38 | DvMF_0787 | | (p)ppGpp synthetase I, SpoT/RelA (RefSeq) | 0.36 | DvMF_2304 | | imidazole glycerol phosphate synthase subunit HisF (RefSeq) | low | > 51 |
| Azospirillum sp. SherDot2 | 0.37 | MPMX19_00838 | | GTP pyrophosphokinase rsh | 0.40 | MPMX19_02542 | | Imidazole glycerol phosphate synthase subunit HisF | — | — |
| Synechococcus elongatus PCC 7942 | 0.37 | Synpcc7942_1377 | | metal dependent phosphohydrolase | 0.37 | Synpcc7942_2087 | hisF | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Rhodospirillum rubrum S1H | 0.37 | Rru_A1856 | | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA (NCBI) | 0.36 | Rru_A3594 | | Histidine biosynthesis protein HisF (NCBI) | — | — |
| Magnetospirillum magneticum AMB-1 | 0.36 | AMB_RS11400 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.37 | AMB_RS22925 | | imidazole glycerol phosphate synthase cyclase subunit | — | — |
| Phaeobacter inhibens DSM 17395 | 0.35 | PGA1_c01010 | | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase SpoT | 0.34 | PGA1_c09240 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Mycobacterium tuberculosis H37Rv | 0.35 | Rv2583c | | Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase) | 0.37 | Rv1605 | | Probable cyclase HisF | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.34 | Ga0059261_1293 | | (p)ppGpp synthetase, RelA/SpoT family | 0.35 | Ga0059261_1048 | | imidazoleglycerol phosphate synthase, cyclase subunit | 0.92 | 28 |
| Dinoroseobacter shibae DFL-12 | 0.34 | Dshi_0194 | | (p)ppGpp synthetase I, SpoT/RelA (RefSeq) | 0.37 | Dshi_2576 | | imidazoleglycerol phosphate synthase, cyclase subunit (RefSeq) | — | — |
| Bifidobacterium breve UCC2003 | 0.34 | BBR_RS16410 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.40 | BBR_RS16095 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.33 | A4249_RS05505 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.57 | A4249_RS10715 | | imidazole glycerol phosphate synthase subunit HisF | 0.87 | 43 |
| Rhodopseudomonas palustris CGA009 | 0.33 | TX73_013955 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.33 | TX73_001625 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.32 | CCNA_01622 | | Rsh ppGpp hydrolase-synthetase | 0.41 | CCNA_03853 | | imidazole glycerol phosphate synthase, cyclase subunit | low | > 67 |
| Caulobacter crescentus NA1000 | 0.32 | CCNA_01622 | | Rsh ppGpp hydrolase-synthetase | 0.41 | CCNA_03853 | | imidazole glycerol phosphate synthase, cyclase subunit | low | > 66 |
| Bosea sp. OAE506 | 0.32 | ABIE41_RS19890 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.34 | ABIE41_RS03810 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Sinorhizobium meliloti 1021 | 0.32 | SMc02659 | | GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein | 0.36 | SMc02569 | | imidazole glycerol phosphate synthase subunit HisF | low | > 103 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.31 | ABZR88_RS15610 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.43 | ABZR88_RS06855 | | imidazole glycerol phosphate synthase subunit HisF | low | > 71 |
| Agrobacterium fabrum C58 | 0.31 | Atu1030 | | GTP pyrophosphohydrolase/synthetase, RelA/SpoT family | 0.37 | Atu0039 | | imidazoleglycerol-phosphate synthase cyclase | 0.62 | 2 |
| Phocaeicola dorei CL03T12C01 | 0.31 | ABI39_RS09710 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.46 | ABI39_RS19930 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Phocaeicola vulgatus CL09T03C04 | 0.31 | HMPREF1058_RS14060 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.46 | HMPREF1058_RS06175 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
| Rhizobium sp. OAE497 | 0.31 | ABIE40_RS06050 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.36 | ABIE40_RS19440 | | imidazole glycerol phosphate synthase subunit HisF | 0.94 | 3 |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.30 | CA264_01425 | | RelA/SpoT family protein | 0.47 | CA264_05110 | | imidazole glycerol phosphate synthase cyclase subunit | low | > 74 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.29 | BT3998 | | GTP pyrophosphokinase (NCBI ptt file) | 0.44 | BT1378 | | imidazole glycerol phosphate synthase subunit hisF (NCBI ptt file) | — | — |
| Bacteroides ovatus ATCC 8483 | 0.29 | BACOVA_04817 | | RelA/SpoT family protein | 0.44 | BACOVA_00219 | | imidazoleglycerol phosphate synthase, cyclase subunit | — | — |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.29 | Echvi_4631 | | (p)ppGpp synthetase, RelA/SpoT family | 0.41 | Echvi_2516 | | imidazoleglycerol phosphate synthase, cyclase subunit | 0.41 | 41 |
| Bacteroides stercoris CC31F | 0.29 | HMPREF1181_RS09205 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | 0.42 | HMPREF1181_RS11070 | | imidazole glycerol phosphate synthase subunit HisF | — | — |
Not shown: 2 genomes with orthologs for b3650 only; 4 genomes with orthologs for b2025 only