Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
Escherichia coli BW25113 | 1.0 | b3941 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI) | 1.0 | b2021 | hisC | histidinol-phosphate aminotransferase (NCBI) | 0.95 | 13 |
Escherichia coli ECRC62 | 1.00 | BNILDI_05725 | metF | methylenetetrahydrofolate reductase | 0.99 | BNILDI_14735 | hisC | histidinol-phosphate transaminase | — | — |
Escherichia coli ECOR27 | 1.00 | NOLOHH_05810 | metF | methylenetetrahydrofolate reductase | 1.00 | NOLOHH_15825 | hisC | histidinol-phosphate transaminase | low | > 57 |
Escherichia coli BL21 | 1.00 | ECD_03827 | | 5,10-methylenetetrahydrofolate reductase | 0.99 | ECD_01923 | | histidinol-phosphate aminotransferase | low | > 60 |
Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_04109 | | 5,10-methylenetetrahydrofolate reductase | 0.99 | OHPLBJKB_01679 | | Histidinol-phosphate aminotransferase | low | > 73 |
Escherichia coli ECOR38 | 1.00 | HEPCGN_12310 | metF | methylenetetrahydrofolate reductase | 0.99 | HEPCGN_03215 | hisC | histidinol-phosphate transaminase | low | > 85 |
Escherichia coli ECRC99 | 1.00 | KEDOAH_14495 | metF | methylenetetrahydrofolate reductase | 1.00 | KEDOAH_03640 | hisC | histidinol-phosphate transaminase | — | — |
Escherichia coli ECRC102 | 1.00 | NIAGMN_11420 | metF | methylenetetrahydrofolate reductase | 1.00 | NIAGMN_22455 | hisC | histidinol-phosphate transaminase | — | — |
Escherichia coli ECRC98 | 1.00 | JDDGAC_17290 | metF | methylenetetrahydrofolate reductase | 1.00 | JDDGAC_28620 | hisC | histidinol-phosphate transaminase | — | — |
Escherichia coli ECRC101 | 1.00 | OKFHMN_13665 | metF | methylenetetrahydrofolate reductase | 1.00 | OKFHMN_24510 | hisC | histidinol-phosphate transaminase | — | — |
Escherichia coli ECRC101 | 1.00 | MCAODC_04165 | metF | methylenetetrahydrofolate reductase | 1.00 | MCAODC_20430 | hisC | histidinol-phosphate transaminase | — | — |
Escherichia fergusonii Becca | 0.99 | EFB2_04672 | | 5,10-methylenetetrahydrofolate reductase | 1.00 | EFB2_01835 | | Histidinol-phosphate aminotransferase | low | > 86 |
Escherichia coli Nissle 1917 | 0.99 | ECOLIN_RS22760 | | methylenetetrahydrofolate reductase | 0.99 | ECOLIN_RS11950 | | histidinol-phosphate transaminase | — | — |
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.97 | GFF2329 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.91 | GFF3911 | | Histidinol-phosphate aminotransferase (EC 2.6.1.9) | low | > 78 |
Enterobacter sp. TBS_079 | 0.95 | MPMX20_04529 | | 5,10-methylenetetrahydrofolate reductase | 0.89 | MPMX20_03003 | | Histidinol-phosphate aminotransferase | 0.74 | 15 |
Klebsiella michiganensis M5al | 0.95 | BWI76_RS00805 | | 5,10-methylenetetrahydrofolate reductase | 0.87 | BWI76_RS18930 | | histidinol-phosphate transaminase | 0.86 | 33 |
Enterobacter asburiae PDN3 | 0.94 | EX28DRAFT_4413 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.89 | EX28DRAFT_0538 | | histidinol-phosphate aminotransferase | low | > 76 |
Pantoea sp. MT58 | 0.92 | IAI47_00890 | | methylenetetrahydrofolate reductase | 0.76 | IAI47_07085 | | histidinol-phosphate transaminase | 0.47 | 48 |
Serratia liquefaciens MT49 | 0.91 | IAI46_24530 | | methylenetetrahydrofolate reductase | 0.78 | IAI46_08205 | | histidinol-phosphate transaminase | low | > 86 |
Dickeya dadantii 3937 | 0.90 | DDA3937_RS00960 | | methylenetetrahydrofolate reductase | 0.73 | DDA3937_RS09730 | | histidinol-phosphate transaminase | 0.39 | 48 |
Rahnella sp. WP5 | 0.89 | EX31_RS14205 | | methylenetetrahydrofolate reductase | 0.76 | EX31_RS11445 | | histidinol-phosphate transaminase | 0.90 | 37 |
Pectobacterium carotovorum WPP14 | 0.88 | HER17_RS00950 | | methylenetetrahydrofolate reductase | 0.74 | HER17_RS12235 | | histidinol-phosphate transaminase | low | > 75 |
Dickeya dianthicola 67-19 | 0.88 | HGI48_RS20415 | | methylenetetrahydrofolate reductase | 0.73 | HGI48_RS09740 | | histidinol-phosphate transaminase | 0.48 | 37 |
Dickeya dianthicola ME23 | 0.88 | DZA65_RS21460 | | methylenetetrahydrofolate reductase | 0.73 | DZA65_RS10050 | | histidinol-phosphate transaminase | 0.67 | 36 |
Erwinia tracheiphila SCR3 | 0.86 | LU632_RS19630 | metF | methylenetetrahydrofolate reductase | 0.76 | LU632_RS08940 | hisC | histidinol-phosphate transaminase | low | > 74 |
Vibrio cholerae E7946 ATCC 55056 | 0.79 | CSW01_13560 | | methylenetetrahydrofolate reductase | 0.58 | CSW01_05755 | | histidinol-phosphate transaminase | low | > 62 |
Shewanella loihica PV-4 | 0.76 | Shew_0522 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.40 | Shew_2199 | | histidinol-phosphate aminotransferase (RefSeq) | 0.95 | 31 |
Shewanella amazonensis SB2B | 0.75 | Sama_3169 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.33 | Sama_1943 | | histidinol-phosphate aminotransferase (RefSeq) | 0.97 | 13 |
Shewanella sp. ANA-3 | 0.75 | Shewana3_3612 | metF | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.42 | Shewana3_1852 | | histidinol phosphate aminotransferase (RefSeq) | 0.97 | 9 |
Shewanella oneidensis MR-1 | 0.75 | SO4054 | metF | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | 0.42 | SO2072 | hisC | histidinol-phosphate aminotransferase (NCBI ptt file) | 0.97 | 13 |
Alteromonas macleodii MIT1002 | 0.70 | MIT1002_03670 | | 5,10-methylenetetrahydrofolate reductase | 0.49 | MIT1002_02634 | | Histidinol-phosphate aminotransferase | low | > 70 |
Kangiella aquimarina DSM 16071 | 0.59 | B158DRAFT_2461 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) (EC 1.5.1.20) | 0.20 | B158DRAFT_2325 | | histidinol-phosphate aminotransferase | low | > 40 |
Magnetospirillum magneticum AMB-1 | 0.55 | AMB_RS02230 | | methylenetetrahydrofolate reductase | 0.19 | AMB_RS00655 | | histidinol-phosphate aminotransferase family protein | — | — |
Azospirillum brasilense Sp245 | 0.54 | AZOBR_RS24245 | | 5 10-methylenetetrahydrofolate reductase | 0.16 | AZOBR_RS20485 | | histidinol-phosphate aminotransferase [EC:2.6.1.9] (from data) | low | > 97 |
Azospirillum sp. SherDot2 | 0.54 | MPMX19_00635 | | 5,10-methylenetetrahydrofolate reductase | 0.16 | MPMX19_04389 | | Histidinol-phosphate aminotransferase | — | — |
Sphingomonas koreensis DSMZ 15582 | 0.54 | Ga0059261_0992 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.14 | Ga0059261_2299 | | histidinol-phosphate aminotransferase | 0.64 | 44 |
Rhodospirillum rubrum S1H | 0.51 | Rru_A1530 | | 5,10-methylenetetrahydrofolate reductase (NCBI) | 0.16 | Rru_A3264 | | Histidinol-phosphate aminotransferase (NCBI) | 0.84 | 26 |
Caulobacter crescentus NA1000 | 0.47 | CCNA_02224 | | methylenetetrahydrofolate reductase | 0.16 | CCNA_02617 | | histidinol-phosphate aminotransferase | low | > 66 |
Caulobacter crescentus NA1000 Δfur | 0.47 | CCNA_02224 | | methylenetetrahydrofolate reductase | 0.16 | CCNA_02617 | | histidinol-phosphate aminotransferase | low | > 67 |
Rhodopseudomonas palustris CGA009 | 0.46 | TX73_019175 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.12 | TX73_023035 | | histidinol-phosphate transaminase | — | — |
Brevundimonas sp. GW460-12-10-14-LB2 | 0.45 | A4249_RS07925 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.15 | A4249_RS11450 | | histidinol-phosphate transaminase | low | > 48 |
Rhizobium sp. OAE497 | 0.41 | ABIE40_RS11950 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.12 | ABIE40_RS17595 | | histidinol-phosphate transaminase | 0.94 | 23 |
Paraburkholderia sabiae LMG 24235 | 0.41 | QEN71_RS28715 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.20 | QEN71_RS27860 | | histidinol-phosphate transaminase | 0.59 | 106 |
Phaeobacter inhibens DSM 17395 | 0.40 | PGA1_c11700 | | 5,10-methylenetetrahydrofolate reductase MetF | 0.15 | PGA1_c25240 | | histidinol-phosphate aminotransferase [EC:2.6.1.9] (from data) | — | — |
Paraburkholderia bryophila 376MFSha3.1 | 0.40 | H281DRAFT_05801 | | 5,10-methylenetetrahydrofolate reductase (NAD(P)) | 0.19 | H281DRAFT_05654 | | histidinol phosphate aminotransferase apoenzyme | low | > 103 |
Paraburkholderia graminis OAS925 | 0.39 | ABIE53_000061 | | methylenetetrahydrofolate reductase (NADPH) | 0.19 | ABIE53_003700 | | histidinol-phosphate aminotransferase | low | > 113 |
Burkholderia phytofirmans PsJN | 0.38 | BPHYT_RS18705 | | 5,10-methylenetetrahydrofolate reductase | 0.18 | BPHYT_RS02830 | | aspartate aminotransferase | low | > 109 |
Cupriavidus basilensis FW507-4G11 | 0.38 | RR42_RS01385 | | 5,10-methylenetetrahydrofolate reductase | 0.18 | RR42_RS18910 | | histidinol-phosphate aminotransferase | — | — |
Ralstonia solanacearum PSI07 | 0.38 | RPSI07_RS23495 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.19 | RPSI07_RS10395 | | histidinol-phosphate transaminase | — | — |
Agrobacterium fabrum C58 | 0.38 | Atu2123 | | methylenetetrahydrofolate reductase | 0.11 | Atu2810 | | cobalamin biosynthetic protein | low | > 89 |
Ralstonia solanacearum IBSBF1503 | 0.38 | RALBFv3_RS09875 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.18 | RALBFv3_RS06840 | | histidinol-phosphate transaminase | — | — |
Ralstonia solanacearum UW163 | 0.38 | UW163_RS03705 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.18 | UW163_RS06775 | | histidinol-phosphate transaminase | — | — |
Dechlorosoma suillum PS | 0.38 | Dsui_0640 | | 5,10-methylenetetrahydrofolate reductase | 0.15 | Dsui_1414 | | histidinol-phosphate aminotransferase | — | — |
Ralstonia solanacearum GMI1000 | 0.38 | RS_RS00460 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.19 | RS_RS14785 | | histidinol-phosphate aminotransferase 1 | — | — |
Ralstonia sp. UNC404CL21Col | 0.37 | ABZR87_RS04865 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.19 | ABZR87_RS02495 | | histidinol-phosphate transaminase | low | > 80 |
Marinobacter adhaerens HP15 | 0.37 | HP15_2917 | | 5,10-methylenetetrahydrofolate reductase-like protein | 0.18 | HP15_2427 | | histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) | 0.92 | 13 |
Dinoroseobacter shibae DFL-12 | 0.36 | Dshi_2080 | | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.14 | Dshi_2946 | | histidinol-phosphate aminotransferase (RefSeq) | — | — |
Pseudomonas sp. S08-1 | 0.36 | OH686_10820 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.17 | OH686_20875 | | histidinol-phosphate transaminase | low | > 80 |
Sinorhizobium meliloti 1021 | 0.36 | SMc01843 | | 5,10-methylenetetrahydrofolate reductase | 0.13 | SMc00710 | | histidinol-phosphate aminotransferase | low | > 103 |
Pseudomonas sp. RS175 | 0.36 | PFR28_04202 | | 5,10-methylenetetrahydrofolate reductase | 0.17 | PFR28_00908 | | Histidinol-phosphate aminotransferase | low | > 88 |
Xanthomonas campestris pv. campestris strain 8004 | 0.36 | Xcc-8004.4336.1 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.38 | Xcc-8004.2947.1 | | Histidinol-phosphate aminotransferase (EC 2.6.1.9) | low | > 74 |
Pseudomonas simiae WCS417 | 0.36 | PS417_26510 | | 5,10-methylenetetrahydrofolate reductase | 0.17 | PS417_08130 | | aspartate aminotransferase | low | > 88 |
Pseudomonas fluorescens FW300-N2E2 | 0.36 | Pf6N2E2_4638 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.18 | Pf6N2E2_2519 | | Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) | low | > 103 |
Pseudomonas putida KT2440 | 0.36 | PP_4977 | | 5,10-methylenetetrahydrofolate reductase | 0.17 | PP_0967 | | histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) | 0.50 | 29 |
Pseudomonas fluorescens SBW25-INTG | 0.36 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.17 | PFLU_RS08100 | | histidinol-phosphate transaminase | low | > 109 |
Pseudomonas fluorescens SBW25 | 0.36 | PFLU_RS28165 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.17 | PFLU_RS08100 | | histidinol-phosphate transaminase | low | > 109 |
Pseudomonas fluorescens FW300-N1B4 | 0.35 | Pf1N1B4_2384 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.18 | Pf1N1B4_349 | | Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) | 0.57 | 66 |
Rhodanobacter sp. FW510-T8 | 0.35 | OKGIIK_11830 | metF | methylenetetrahydrofolate reductase [NAD(P)H] | 0.38 | OKGIIK_04955 | hisC | histidinol-phosphate transaminase | low | > 52 |
Rhodanobacter denitrificans FW104-10B01 | 0.35 | LRK54_RS12030 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.38 | LRK54_RS01600 | | histidinol-phosphate transaminase | 0.53 | 53 |
Herbaspirillum seropedicae SmR1 | 0.35 | HSERO_RS21425 | | 5,10-methylenetetrahydrofolate reductase | 0.16 | HSERO_RS23520 | | histidinol-phosphate aminotransferase | low | > 78 |
Pseudomonas fluorescens FW300-N2C3 | 0.35 | AO356_13605 | | 5,10-methylenetetrahydrofolate reductase | 0.18 | AO356_03460 | | aspartate aminotransferase | low | > 104 |
Rhodanobacter denitrificans MT42 | 0.35 | LRK55_RS11765 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.37 | LRK55_RS01380 | | histidinol-phosphate transaminase | low | > 63 |
Dyella japonica UNC79MFTsu3.2 | 0.35 | ABZR86_RS11570 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.35 | ABZR86_RS06725 | | histidinol-phosphate transaminase | 0.95 | 18 |
Pseudomonas fluorescens FW300-N2E3 | 0.35 | AO353_08015 | | 5,10-methylenetetrahydrofolate reductase | 0.18 | AO353_02065 | | aspartate aminotransferase | 0.44 | 91 |
Pseudomonas stutzeri RCH2 | 0.35 | Psest_0313 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.18 | Psest_1985 | | histidinol-phosphate aminotransferase | low | > 67 |
Pseudomonas fluorescens GW456-L13 | 0.35 | PfGW456L13_1050 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.17 | PfGW456L13_2177 | | Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) | low | > 87 |
Pseudomonas syringae pv. syringae B728a | 0.35 | Psyr_0459 | | 5,10-methylenetetrahydrofolate reductase | 0.15 | Psyr_4132 | | histidinol phosphate aminotransferase apoenzyme | 0.67 | 9 |
Pseudomonas syringae pv. syringae B728a ΔmexB | 0.35 | Psyr_0459 | | 5,10-methylenetetrahydrofolate reductase | 0.15 | Psyr_4132 | | histidinol phosphate aminotransferase apoenzyme | low | > 86 |
Castellaniella sp019104865 MT123 | 0.34 | ABCV34_RS13550 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.18 | ABCV34_RS02645 | | histidinol-phosphate transaminase | low | > 48 |
Lysobacter sp. OAE881 | 0.34 | ABIE51_RS16490 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.34 | ABIE51_RS13320 | | histidinol-phosphate transaminase | 0.96 | 35 |
Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.34 | GFF1692 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.19 | GFF1493 | | Histidinol-phosphate aminotransferase (EC 2.6.1.9) | — | — |
Acidovorax sp. GW101-3H11 | 0.34 | Ac3H11_3045 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.18 | Ac3H11_4729 | | histidinol-phosphate transaminase (EC 2.6.1.9) (from data) | — | — |
Variovorax sp. OAS795 | 0.33 | ABID97_RS25015 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.17 | ABID97_RS23145 | | histidinol-phosphate transaminase | low | > 91 |
Variovorax sp. SCN45 | 0.32 | GFF2055 | | 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) | 0.18 | GFF5348 | | Histidinol-phosphate aminotransferase (EC 2.6.1.9) | low | > 127 |
Acinetobacter radioresistens SK82 | 0.31 | MPMX26_01002 | | 5,10-methylenetetrahydrofolate reductase | 0.17 | MPMX26_02586 | | Histidinol-phosphate aminotransferase | low | > 36 |
Desulfovibrio vulgaris Hildenborough JW710 | 0.28 | DVU0997 | metF | 5,10-methylenetetrahydrofolate reductase (TIGR) | 0.19 | DVU1029 | hisC | histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) | 0.75 | 41 |
Desulfovibrio vulgaris Miyazaki F | 0.27 | DvMF_3034 | | 5,10-methylenetetrahydrofolate reductase (RefSeq) | 0.18 | DvMF_0908 | | histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) | — | — |
Bifidobacterium breve UCC2003 | 0.24 | BBR_RS15410 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.14 | BBR_RS17050 | | histidinol-phosphate transaminase | low | > 34 |
Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.22 | ABZR88_RS20935 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.34 | ABZR88_RS06875 | | histidinol-phosphate transaminase | low | > 71 |
Parabacteroides merdae CL09T00C40 | 0.21 | HMPREF1078_RS07860 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.32 | HMPREF1078_RS02445 | | histidinol-phosphate transaminase | low | > 61 |
Echinicola vietnamensis KMM 6221, DSM 17526 | 0.21 | Echvi_3637 | | 5,10-methylenetetrahydrofolate reductase, prokaryotic form | 0.32 | Echvi_2458 | | histidinol-phosphate aminotransferase | 0.87 | 31 |
Pedobacter sp. GW460-11-11-14-LB5 | 0.21 | CA265_RS23445 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.36 | CA265_RS03630 | | histidinol-phosphate transaminase | 0.95 | 16 |
Pontibacter actiniarum KMM 6156, DSM 19842 | 0.20 | CA264_16780 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.35 | CA264_05035 | | histidinol-phosphate transaminase | low | > 74 |
Phocaeicola dorei CL03T12C01 | 0.19 | ABI39_RS15570 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.28 | ABI39_RS11840 | | histidinol-phosphate transaminase | low | > 72 |
Bacteroides thetaiotaomicron VPI-5482 | 0.18 | BT3821 | | 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) | 0.27 | BT0202 | | histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) | low | > 81 |
Phocaeicola vulgatus CL09T03C04 | 0.18 | HMPREF1058_RS01490 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.28 | HMPREF1058_RS15880 | | histidinol-phosphate transaminase | low | > 67 |
Bacteroides stercoris CC31F | 0.17 | HMPREF1181_RS00120 | | methylenetetrahydrofolate reductase [NAD(P)H] | 0.29 | HMPREF1181_RS04855 | | histidinol-phosphate transaminase | low | > 56 |
Bacteroides ovatus ATCC 8483 | 0.15 | BACOVA_03666 | | methylenetetrahydrofolate reductase (NAD(P)H) | 0.29 | BACOVA_01233 | | histidinol-phosphate transaminase | low | > 94 |
Not shown: 2 genomes with orthologs for b3941 only; 4 genomes with orthologs for b2021 only