| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| o | Escherichia coli BL21 | ECD_03119 | | global DNA-binding transcriptional dual regulator | sig. | 100 | 100 |
| o | Escherichia fergusonii Becca | EFB2_00563 | | DNA-binding protein Fis | strong | 100 | 100 |
| o | Escherichia coli ECOR27 | NOLOHH_09465 | fis | DNA-binding transcriptional regulator Fis | no data | 100 | 100 |
| o | Escherichia coli ECOR38 | HEPCGN_16500 | fis | DNA-binding transcriptional regulator Fis | sig. | 100 | 100 |
| o | Escherichia coli ECRC100 | OKFHMN_17680 | fis | DNA-binding transcriptional regulator Fis | cofit | 100 | 100 |
| o | Escherichia coli ECRC101 | MCAODC_08200 | fis | DNA-binding transcriptional regulator Fis | sig. | 100 | 100 |
| o | Escherichia coli ECRC102 | NIAGMN_15440 | fis | DNA-binding transcriptional regulator Fis | strong | 100 | 100 |
| o | Escherichia coli ECRC62 | BNILDI_02055 | fis | DNA-binding transcriptional regulator Fis | no data | 100 | 100 |
| o | Escherichia coli ECRC98 | JDDGAC_21305 | fis | DNA-binding transcriptional regulator Fis | no data | 100 | 100 |
| o | Escherichia coli ECRC99 | KEDOAH_10470 | fis | DNA-binding transcriptional regulator Fis | no data | 100 | 100 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00444 | | DNA-binding protein Fis | no data | 100 | 100 |
| o | Escherichia coli Nissle 1917 | ECOLIN_RS18730 | | DNA-binding transcriptional regulator Fis | strong | 100 | 100 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_3314 | | Factor for inversion stimulation Fis, transcriptional activator | insig. | 100 | 100 |
| o | Enterobacter sp. TBS_079 | MPMX20_04170 | | DNA-binding protein Fis | strong | 100 | 100 |
| o | Erwinia amylovora T8 | OLJFJH_06850 | | DNA-binding transcriptional regulator Fis | no data | 100 | 100 |
| | Escherichia coli BW25113 | b3261 | fis | DNA-binding protein Fis (NCBI) | strong | 100 | 100 |
| o | Klebsiella michiganensis M5al | BWI76_RS25570 | | Fis family transcriptional regulator | no data | 100 | 100 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_06330 | | DNA-binding transcriptional regulator Fis | no data | 100 | 100 |
| o | Klebsiella pneumoniae MRSN742743 | KFA93_RS13585 | fis;inference=COORDINATES | DNA-binding transcriptional regulator Fis | no data | 100 | 100 |
| o | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF2123 | | DNA-binding protein Fis | no data | 100 | 100 |
| o | Serratia liquefaciens MT49 | IAI46_22780 | | DNA-binding transcriptional regulator Fis | no data | 100 | 100 |
| o | Pantoea sp. MT58 | IAI47_02380 | | DNA-binding transcriptional regulator Fis | strong | 99 | 100 |
| o | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS10975 | | DNA-binding transcriptional regulator Fis | no data | 99 | 100 |
| o | Rahnella sp. WP5 | EX31_RS12175 | | DNA-binding transcriptional regulator Fis | cofit | 99 | 100 |
| o | Dickeya dadantii 3937 | DDA3937_RS01370 | | DNA-binding transcriptional regulator Fis | no data | 99 | 100 |
| o | Dickeya dianthicola 67-19 | HGI48_RS01290 | | DNA-binding transcriptional regulator Fis | strong | 99 | 100 |
| o | Dickeya dianthicola ME23 | DZA65_RS01350 | | DNA-binding transcriptional regulator Fis | sig. | 99 | 100 |
| o | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_13495 | fis | DNA-binding transcriptional regulator Fis | no data | 98 | 100 |
| o | Erwinia tracheiphila SCR3 | LU632_RS21515 | fis | DNA-binding transcriptional regulator Fis | strong | 98 | 100 |
| o | Pectobacterium carotovorum WPP14 | HER17_RS20240 | | DNA-binding transcriptional regulator Fis | insig. | 98 | 100 |
| o | Vibrio cholerae E7946 ATCC 55056 | CSW01_01490 | | Fis family transcriptional regulator | strong | 83 | 100 |
| o | Shewanella sp. ANA-3 | Shewana3_0398 | fis | DNA-binding protein Fis (RefSeq) | no data | 63 | 100 |
| o | Shewanella oneidensis MR-1 | SO0393 | fis | DNA-binding protein Fis (NCBI ptt file) | strong | 63 | 100 |
| o | Shewanella amazonensis SB2B | Sama_3226 | fis | DNA-binding protein Fis (RefSeq) | no data | 61 | 100 |
| o | Shewanella loihica PV-4 | Shew_0329 | | Fis family transcriptional regulator (RefSeq) | no data | 60 | 100 |
| o | Alteromonas macleodii MIT1002 | MIT1002_03958 | | Hin recombinational enhancer-binding protein | no data | 67 | 100 |
| o | Marinobacter adhaerens HP15 | HP15_3226 | | fis-like DNA-binding protein | no data | 61 | 94 |
| o | Pseudomonas sp. S08-1 | OH686_07615 | | DNA-binding protein Fis | no data | 52 | 99 |
| | Pseudomonas sp. BP01 | JOY50_RS17630 | fis | DNA-binding transcriptional regulator Fis | no data | 65 | 72 |
| | Pseudomonas putida KT2440 | PP_4821 | | putative Fis-like DNA-binding protein | no data | 65 | 72 |
| | Pseudomonas stutzeri RCH2 | Psest_1015 | | Factor for inversion stimulation Fis, transcriptional activator | no data | 63 | 72 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS10045 | fis;inference=COORDINATES | DNA-binding transcriptional regulator Fis | no data | 62 | 72 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_29295 | | DNA-binding transcriptional regulator Fis | no data | 62 | 72 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS52010 | fis;inference=COORDINATES | DNA-binding transcriptional regulator Fis | no data | 62 | 72 |
| o | Pseudomonas segetis P6 | ACVTMO_RS20365 | fis | DNA-binding transcriptional regulator Fis | no data | 51 | 97 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_56 | | DNA-binding protein Fis | no data | 63 | 72 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS03020 | | DNA-binding transcriptional regulator Fis | no data | 64 | 70 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS03020 | | DNA-binding transcriptional regulator Fis | no data | 64 | 70 |
| | Pseudomonas sp. DMC3 | GFF3309 | | DNA-binding protein Fis | no data | 64 | 70 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_00821 | | DNA-binding protein Fis | no data | 64 | 70 |
| | Pseudomonas orientalis W4I3 | QF045_RS05980 | | DNA-binding transcriptional regulator Fis | no data | 64 | 70 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_4405 | | DNA-binding protein Fis | no data | 64 | 70 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_4405 | | DNA-binding protein Fis | no data | 64 | 70 |
| | Pseudomonas simiae WCS417 | PS417_02945 | | Fis family transcriptional regulator | no data | 64 | 70 |
| | Pseudomonas sp. RS175 | PFR28_05215 | | DNA-binding protein Fis | no data | 64 | 70 |
| | Pseudomonas sp. SVBP6 | COO64_RS18310 | fis | DNA-binding transcriptional regulator Fis | no data | 64 | 70 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_1314 | | DNA-binding protein Fis | no data | 62 | 72 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_13655 | | Fis family transcriptional regulator | no data | 64 | 70 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_08220 | | Fis family transcriptional regulator | no data | 64 | 70 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_3518 | | DNA-binding protein Fis | no data | 62 | 72 |
| | Acinetobacter baumannii LAC-4 | RR41_RS06700 | | DNA-binding transcriptional regulator Fis | no data | 58 | 72 |
| | Acinetobacter radioresistens SK82 | MPMX26_01142 | | DNA-binding protein Fis | no data | 58 | 72 |
| o | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.671.1 | | DNA-binding protein Fis | no data | 48 | 86 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0165 | | Factor for inversion stimulation Fis, transcriptional activator | no data | 54 | 72 |
| | Lysobacter sp. OAE881 | ABIE51_RS17755 | | DNA-binding transcriptional regulator Fis | no data | 48 | 74 |
| | Methylophilus sp. DMC18 | GFF1645 | | DNA-binding protein Fis | no data | 47 | 77 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS02055 | | Fis family transcriptional regulator | no data | 43 | 78 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS07645 | | Fis family transcriptional regulator | strong | 38 | 78 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS11690 | | Fis family transcriptional regulator | strong | 38 | 78 |
| | Ralstonia solanacearum GMI1000 | RS_RS02510 | | Fis family transcriptional regulator | strong | 38 | 78 |
| | Ralstonia solanacearum UW163 | UW163_RS01895 | | Fis family transcriptional regulator | no data | 38 | 78 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_04250 | | DNA-binding protein Fis | sig. | 45 | 72 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS21525 | | Fis family transcriptional regulator | no data | 38 | 78 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS16590 | | Fis family transcriptional regulator | sig. | 45 | 72 |
| | Paraburkholderia graminis OAS925 | ABIE53_003490 | | Fis family transcriptional regulator | sig. | 45 | 72 |
| | Variovorax sp. OAS795 | ABID97_RS24730 | | Fis family transcriptional regulator | strong | 42 | 78 |
| | Variovorax sp. SCN45 | GFF2145 | | DNA-binding protein Fis | no data | 42 | 78 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS26775 | | Fis family transcriptional regulator | cofit | 41 | 78 |
| o | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS17055 | | helix-turn-helix domain-containing protein | no data | 40 | 82 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF635 | | DNA-binding protein Fis | no data | 41 | 76 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3995 | | DNA-binding protein Fis | no data | 39 | 76 |
| | Azospirillum brasilense Sp245 | AZOBR_RS14430 | | chemotaxis protein CheY | strong | 49 | 68 |
| | Azospirillum sp. SherDot2 | MPMX19_01112 | | DNA-binding transcriptional regulator NtrC | no data | 47 | 68 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_16810 | | Putative Fis-like DNA-binding protein | no data | 43 | 84 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS02725 | | Fis family transcriptional regulator | no data | 39 | 78 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS01590 | | Fis family transcriptional regulator | no data | 44 | 76 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS06565 | | helix-turn-helix domain-containing protein | no data | 44 | 76 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS06820 | | Fis family transcriptional regulator | sig. | 44 | 76 |
| | Dechlorosoma suillum PS | Dsui_1594 | | Factor for inversion stimulation Fis, transcriptional activator | no data | 50 | 67 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS07965 | | helix-turn-helix domain-containing protein | no data | 47 | 74 |
| | Agrobacterium fabrum C58 | Atu1446 | | two component response regulator | strong | 34 | 100 |
| | Caulobacter crescentus NA1000 | CCNA_01815 | | nitrogen assimilation regulatory protein NtrC | strong | 46 | 68 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_01815 | | nitrogen assimilation regulatory protein NtrC | no data | 46 | 68 |
| | Sinorhizobium meliloti 1021 | SMc01043 | | nitrogen assimilation regulatory protein | strong | 41 | 70 |
| | Rhizobium sp. OAE497 | ABIE40_RS09090 | | nitrogen regulation protein NR(I) | strong | 33 | 92 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS11950 | | nitrogen regulation protein NR(I) | no data | 44 | 68 |
| | Rhodopseudomonas palustris CGA009 | TX73_013420 | | nitrogen regulation protein NR(I) | strong | 46 | 68 |
| | Dinoroseobacter shibae DFL-12 | Dshi_1574 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | strong | 44 | 67 |
| | Bosea sp. OAE506 | ABIE41_RS16785 | | nitrogen regulation protein NR(I) | insig. | 44 | 72 |
| | Rhodospirillum rubrum S1H | Rru_A1678 | | Nitrogen Metabolism Transcriptional Regulator, NtrC, Fis Family (NCBI) | strong | 41 | 68 |
| | Xanthobacter sp. DMC5 | GFF848 | | DNA-binding transcriptional regulator NtrC | no data | 40 | 78 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c14790 | | nitrogen regulation protein NtrC | no data | 40 | 72 |
| | Sphingobium sp. HT1-2 | GFF1148 | | Nitrogen regulation protein NR(I), GlnG (=NtrC) | strong | 42 | 73 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0137 | | nitrogen regulation protein NR(I) | strong | 45 | 50 |
| | Agrobacterium fabrum C58 | Atu2225 | | transcriptional regulator | strong | 49 | 42 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0110 | ntrC | sigma-54 dependent transcriptional regulator/response regulator (TIGR) | cofit | 36 | 57 |
| | Sinorhizobium meliloti 1021 | SMc04011 | | sigma-54-dependent transcription regulator protein | insig. | 43 | 45 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS11455 | ntrC;inference=COORDINATES | two-component system response regulator NtrC | strong | 30 | 68 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_27895 | | two-component system response regulator NtrC | sig. | 30 | 68 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS50645 | ntrC;inference=COORDINATES | two-component system response regulator NtrC | strong | 30 | 68 |
| | Agrobacterium fabrum C58 | Atu3764 | | sigma 54 dependent transcriptional activator | sig. | 41 | 45 |
| | Pseudomonas sp. BP01 | JOY50_RS09450 | ntrC | nitrogen regulation protein NR(I) | cofit | 30 | 68 |
| | Rhizobium sp. OAE497 | ABIE40_RS16175 | | sigma-54 dependent transcriptional regulator | strong | 41 | 45 |
| | Fusobacterium nucleatum SB010 | HUW76_02090 | | sigma-54-dependent Fis family transcriptional regulator | cofit | 32 | 69 |
| | Pseudomonas stutzeri RCH2 | Psest_3932 | | nitrogen regulation protein NR(I) | strong | 30 | 67 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1933 | | PAS modulated sigma54 specific transcriptional regulator, Fis family (RefSeq) | insig. | 41 | 55 |
| | Pseudomonas putida KT2440 | PP_5048 | | two-component system DNA-binding transcriptional dual regulator GlnL/GlnG | strong | 30 | 68 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0015 | | rteB, two-component system response regulator (NCBI ptt file) | insig. | 36 | 57 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS10290 | | Fis family transcriptional regulator | no data | 34 | 63 |
| | Caulobacter crescentus NA1000 | CCNA_00954 | | AAA-family response regulator flbD | strong | 49 | 42 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00954 | | AAA-family response regulator flbD | cofit | 49 | 42 |
| | Rhodospirillum rubrum S1H | Rru_A0540 | | Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) | insig. | 46 | 42 |
| | Escherichia coli BL21 | ECD_02147 | | fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein | insig. | 41 | 45 |
| | Escherichia fergusonii Becca | EFB2_01635 | | Regulatory protein AtoC | insig. | 41 | 45 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01490 | | Regulatory protein AtoC | insig. | 41 | 45 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS12965 | | acetoacetate metabolism transcriptional regulator AtoC | no data | 41 | 45 |
| | Escherichia coli BW25113 | b2220 | atoC | fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein (NCBI) | insig. | 41 | 45 |
| | Pseudomonas segetis P6 | ACVTMO_RS21260 | ntrC | nitrogen regulation protein NR(I) | strong | 27 | 68 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1993 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | sig. | 26 | 82 |
| | Escherichia coli ECOR38 | HEPCGN_22430 | atoC | acetoacetate metabolism transcriptional regulator AtoC | insig. | 41 | 45 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS38320 | | sigma 54-interacting transcriptional regulator | insig. | 32 | 63 |
| | Klebsiella michiganensis M5al | BWI76_RS00385 | | nitrogen assimilation regulatory protein | strong | 29 | 87 |
| | Azospirillum sp. SherDot2 | MPMX19_04090 | | Anaerobic nitric oxide reductase transcription regulator NorR | cofit | 45 | 43 |
| | Azospirillum brasilense Sp245 | AZOBR_RS20165 | | ATPase AAA | strong | 43 | 50 |