Conservation of cofitness between SMc00554 and SMc03823 in Sinorhizobium meliloti 1021

91 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sinorhizobium meliloti 1021 1.0 SMc00554 amidophosphoribosyltransferase 1.0 SMc03823 isopropylmalate isomerase large subunit 0.95 17
Agrobacterium fabrum C58 0.86 Atu1075 amidophosphoribosyltransferase 0.88 Atu2709 3-isopropylmalate dehydratase, large subunit 0.93 10
Rhizobium sp. OAE497 0.84 ABIE40_RS06270 amidophosphoribosyltransferase 0.91 ABIE40_RS18380 3-isopropylmalate dehydratase large subunit 0.91 7
Bosea sp. OAE506 0.67 ABIE41_RS17810 amidophosphoribosyltransferase 0.81 ABIE41_RS11660 3-isopropylmalate dehydratase large subunit
Rhodopseudomonas palustris CGA009 0.64 TX73_015990 amidophosphoribosyltransferase 0.77 TX73_001245 3-isopropylmalate dehydratase large subunit
Caulobacter crescentus NA1000 0.63 CCNA_01730 amidophosphoribosyltransferase 0.69 CCNA_00196 3-isopropylmalate dehydratase large subunit 0.73 39
Caulobacter crescentus NA1000 Δfur 0.63 CCNA_01730 amidophosphoribosyltransferase 0.69 CCNA_00196 3-isopropylmalate dehydratase large subunit low > 67
Azospirillum brasilense Sp245 0.57 AZOBR_RS08310 amidophosphoribosyltransferase 0.75 AZOBR_RS03545 isopropylmalate isomerase 0.69 8
Azospirillum sp. SherDot2 0.56 MPMX19_00906 Amidophosphoribosyltransferase 0.75 MPMX19_01998 3-isopropylmalate dehydratase large subunit 0.85 28
Rhodospirillum rubrum S1H 0.56 Rru_A0404 Amidophosphoribosyl transferase (NCBI) 0.75 Rru_A1189 3-isopropylmalate dehydratase large subunit region (NCBI) low > 58
Brevundimonas sp. GW460-12-10-14-LB2 0.56 A4249_RS03735 amidophosphoribosyltransferase 0.50 A4249_RS10005 3-isopropylmalate dehydratase large subunit
Magnetospirillum magneticum AMB-1 0.56 AMB_RS10545 amidophosphoribosyltransferase 0.74 AMB_RS20560 3-isopropylmalate dehydratase large subunit
Sphingomonas koreensis DSMZ 15582 0.55 Ga0059261_3626 amidophosphoribosyltransferase (EC 2.4.2.14) 0.64 Ga0059261_4223 3-isopropylmalate dehydratase, large subunit
Dinoroseobacter shibae DFL-12 0.51 Dshi_2132 amidophosphoribosyltransferase (RefSeq) 0.67 Dshi_0085 3-isopropylmalate dehydratase, large subunit (RefSeq) 0.75 23
Phaeobacter inhibens DSM 17395 0.51 PGA1_c10810 amidophosphoribosyltransferase PurF 0.70 PGA1_c29780 3-isopropylmalate dehydratase large subunit 0.90 9
Bifidobacterium breve UCC2003 0.43 BBR_RS13380 amidophosphoribosyltransferase 0.56 BBR_RS19630 3-isopropylmalate dehydratase large subunit low > 34
Desulfovibrio vulgaris Miyazaki F 0.43 DvMF_2307 amidophosphoribosyltransferase (RefSeq) 0.22 DvMF_1792 3-isopropylmalate dehydratase large subunit (RefSeq) 0.76 32
Desulfovibrio vulgaris Hildenborough JW710 0.42 DVU0161 purF amidophosphoribosyltransferase (TIGR) 0.23 DVU2982 leuC 3-isopropylmalate dehydratase / (R)-citramalate isomerase, large subunit LeuC (EC 4.2.1.33; EC 4.2.1.35) (from data)
Mycobacterium tuberculosis H37Rv 0.37 Rv0808 Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) 0.61 Rv2988c Probable 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI)
Synechococcus elongatus PCC 7942 0.36 Synpcc7942_0004 purF amidophosphoribosyltransferase 0.50 Synpcc7942_1898 leuC isopropylmalate isomerase large subunit
Methanococcus maripaludis JJ 0.35 MMJJ_RS08440 amidophosphoribosyltransferase 0.24 MMJJ_RS08425 3-isopropylmalate dehydratase large subunit
Methanococcus maripaludis S2 0.34 MMP_RS05915 amidophosphoribosyltransferase 0.24 MMP_RS05930 3-isopropylmalate dehydratase large subunit
Dickeya dadantii 3937 0.30 DDA3937_RS14435 amidophosphoribosyltransferase 0.64 DDA3937_RS18125 3-isopropylmalate dehydratase large subunit 0.66 43
Shewanella amazonensis SB2B 0.30 Sama_2146 amidophosphoribosyltransferase (RefSeq) 0.61 Sama_0337 isopropylmalate isomerase large subunit (RefSeq) 0.76 52
Shewanella loihica PV-4 0.30 Shew_2302 amidophosphoribosyltransferase (RefSeq) 0.63 Shew_3470 isopropylmalate isomerase large subunit (RefSeq) 0.80 38
Pectobacterium carotovorum WPP14 0.29 HER17_RS07020 amidophosphoribosyltransferase 0.64 HER17_RS03075 3-isopropylmalate dehydratase large subunit 0.97 7
Dickeya dianthicola 67-19 0.29 HGI48_RS14405 amidophosphoribosyltransferase 0.64 HGI48_RS18065 3-isopropylmalate dehydratase large subunit 0.76 14
Dickeya dianthicola ME23 0.29 DZA65_RS15335 amidophosphoribosyltransferase 0.64 DZA65_RS19210 3-isopropylmalate dehydratase large subunit 0.59 60
Escherichia coli Nissle 1917 0.29 ECOLIN_RS13405 amidophosphoribosyltransferase 0.66 ECOLIN_RS00390 3-isopropylmalate dehydratase large subunit
Escherichia coli ECRC98 0.29 JDDGAC_26675 purF amidophosphoribosyltransferase 0.66 JDDGAC_14320 leuC1 3-isopropylmalate dehydratase large subunit 1
Escherichia coli ECOR38 0.29 HEPCGN_21910 purF amidophosphoribosyltransferase 0.66 HEPCGN_08705 leuC1 3-isopropylmalate dehydratase large subunit 1 low > 85
Escherichia fergusonii Becca 0.29 EFB2_01546 Amidophosphoribosyltransferase 0.65 EFB2_03973 3-isopropylmalate dehydratase large subunit low > 86
Klebsiella michiganensis M5al 0.29 BWI76_RS20350 amidophosphoribosyltransferase 0.65 BWI76_RS04670 3-isopropylmalate dehydratase large subunit 0.81 29
Escherichia coli HS(pFamp)R (ATCC 700891) 0.29 OHPLBJKB_01393 Amidophosphoribosyltransferase 0.66 OHPLBJKB_03585 3-isopropylmalate dehydratase large subunit low > 73
Escherichia coli ECRC101 0.29 OKFHMN_22715 purF amidophosphoribosyltransferase 0.66 OKFHMN_10725 leuC1 3-isopropylmalate dehydratase large subunit 1
Escherichia coli ECRC101 0.29 MCAODC_13755 purF amidophosphoribosyltransferase 0.66 MCAODC_01240 leuC1 3-isopropylmalate dehydratase large subunit 1
Escherichia coli ECRC102 0.29 NIAGMN_20485 purF amidophosphoribosyltransferase 0.66 NIAGMN_08575 leuC1 3-isopropylmalate dehydratase large subunit 1
Escherichia coli ECRC99 0.29 KEDOAH_05480 purF amidophosphoribosyltransferase 0.66 KEDOAH_17430 leuC1 3-isopropylmalate dehydratase large subunit 1
Escherichia coli BW25113 0.29 b2312 purF amidophosphoribosyltransferase (NCBI) 0.66 b0072 leuC isopropylmalate isomerase large subunit (NCBI) 0.76 51
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.29 GFF1927 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.65 GFF166 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 78
Pantoea sp. MT58 0.29 IAI47_06275 amidophosphoribosyltransferase 0.65 IAI47_16010 3-isopropylmalate dehydratase large subunit 0.78 41
Enterobacter sp. TBS_079 0.29 MPMX20_03247 Amidophosphoribosyltransferase 0.65 MPMX20_00767 3-isopropylmalate dehydratase large subunit 1 0.82 46
Escherichia coli BL21 0.29 ECD_02237 amidophosphoribosyltransferase 0.66 ECD_00074 3-isopropylmalate dehydratase large subunit low > 60
Escherichia coli ECOR27 0.29 NOLOHH_14335 purF amidophosphoribosyltransferase 0.66 NOLOHH_03070 leuC1 3-isopropylmalate dehydratase large subunit 1 low > 57
Erwinia tracheiphila SCR3 0.29 LU632_RS07865 purF amidophosphoribosyltransferase 0.61 LU632_RS02870 leuC 3-isopropylmalate dehydratase large subunit 0.70 29
Escherichia coli ECRC62 0.29 BNILDI_13255 purF amidophosphoribosyltransferase 0.66 BNILDI_08540 leuC1 3-isopropylmalate dehydratase large subunit 1
Serratia liquefaciens MT49 0.29 IAI46_17810 amidophosphoribosyltransferase 0.62 IAI46_03345 3-isopropylmalate dehydratase large subunit low > 86
Enterobacter asburiae PDN3 0.29 EX28DRAFT_0292 amidophosphoribosyltransferase (EC 2.4.2.14) 0.65 EX28DRAFT_3668 3-isopropylmalate dehydratase, large subunit low > 76
Shewanella oneidensis MR-1 0.29 SO3064 purF amidophosphoribosyltransferase (NCBI ptt file) 0.63 SO4234 leuC 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) 0.84 33
Shewanella sp. ANA-3 0.29 Shewana3_1483 amidophosphoribosyltransferase (RefSeq) 0.63 Shewana3_3759 isopropylmalate isomerase large subunit (RefSeq) 0.86 37
Rahnella sp. WP5 0.28 EX31_RS19570 amidophosphoribosyltransferase 0.65 EX31_RS03690 3-isopropylmalate dehydratase large subunit 0.92 22
Alteromonas macleodii MIT1002 0.28 MIT1002_02524 Amidophosphoribosyltransferase 0.61 MIT1002_00947 3-isopropylmalate dehydratase large subunit 0.98 11
Vibrio cholerae E7946 ATCC 55056 0.28 CSW01_05115 amidophosphoribosyltransferase 0.61 CSW01_12605 3-isopropylmalate dehydratase large subunit low > 62
Dechlorosoma suillum PS 0.28 Dsui_3186 amidophosphoribosyltransferase 0.62 Dsui_3201 3-isopropylmalate dehydratase, large subunit
Ralstonia solanacearum PSI07 0.28 RPSI07_RS14765 amidophosphoribosyltransferase 0.67 RPSI07_RS14695 3-isopropylmalate dehydratase large subunit
Paraburkholderia bryophila 376MFSha3.1 0.28 H281DRAFT_06060 amidophosphoribosyltransferase 0.66 H281DRAFT_06075 3-isopropylmalate dehydratase, large subunit 0.37 58
Rhodanobacter denitrificans FW104-10B01 0.28 LRK54_RS01340 amidophosphoribosyltransferase 0.57 LRK54_RS07375 3-isopropylmalate dehydratase large subunit low > 59
Rhodanobacter denitrificans MT42 0.28 LRK55_RS01105 amidophosphoribosyltransferase 0.57 LRK55_RS07105 3-isopropylmalate dehydratase large subunit low > 63
Paraburkholderia graminis OAS925 0.28 ABIE53_004816 amidophosphoribosyltransferase 0.66 ABIE53_004801 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit
Burkholderia phytofirmans PsJN 0.28 BPHYT_RS33840 amidophosphoribosyltransferase 0.66 BPHYT_RS33915 isopropylmalate isomerase 0.85 17
Acidovorax sp. GW101-3H11 0.28 Ac3H11_2608 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.65 Ac3H11_1525 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.83 15
Dyella japonica UNC79MFTsu3.2 0.28 ABZR86_RS06775 amidophosphoribosyltransferase 0.52 ABZR86_RS15960 3-isopropylmalate dehydratase large subunit 0.95 22
Ralstonia solanacearum UW163 0.28 UW163_RS11175 amidophosphoribosyltransferase 0.66 UW163_RS11105 3-isopropylmalate dehydratase large subunit
Ralstonia solanacearum IBSBF1503 0.28 RALBFv3_RS02550 amidophosphoribosyltransferase 0.66 RALBFv3_RS02620 3-isopropylmalate dehydratase large subunit
Hydrogenophaga sp. GW460-11-11-14-LB1 0.27 GFF300 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.65 GFF3363 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Kangiella aquimarina DSM 16071 0.27 B158DRAFT_1488 amidophosphoribosyltransferase (EC 2.4.2.14) 0.66 B158DRAFT_1319 3-isopropylmalate dehydratase, large subunit
Ralstonia solanacearum GMI1000 0.27 RS_RS09930 amidophosphoribosyltransferase 0.66 RS_RS10000 3-isopropylmalate dehydratase large subunit
Lysobacter sp. OAE881 0.27 ABIE51_RS06180 amidophosphoribosyltransferase 0.52 ABIE51_RS17575 3-isopropylmalate dehydratase large subunit low > 62
Herbaspirillum seropedicae SmR1 0.27 HSERO_RS16445 amidophosphoribosyltransferase 0.67 HSERO_RS16515 isopropylmalate isomerase
Variovorax sp. SCN45 0.27 GFF3089 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.66 GFF3890 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) low > 127
Rhodanobacter sp. FW510-T8 0.27 OKGIIK_05570 purF amidophosphoribosyltransferase 0.50 OKGIIK_13585 leuC 3-isopropylmalate dehydratase large subunit low > 52
Variovorax sp. OAS795 0.27 ABID97_RS21635 amidophosphoribosyltransferase 0.65 ABID97_RS08465 3-isopropylmalate dehydratase large subunit
Pseudomonas sp. S08-1 0.27 OH686_04420 amidophosphoribosyltransferase 0.64 OH686_04480 3-isopropylmalate dehydratase large subunit
Paraburkholderia sabiae LMG 24235 0.27 QEN71_RS17680 amidophosphoribosyltransferase 0.66 QEN71_RS17605 3-isopropylmalate dehydratase large subunit 0.68 79
Pseudomonas fluorescens SBW25 0.27 PFLU_RS20515 amidophosphoribosyltransferase 0.65 PFLU_RS20580 3-isopropylmalate dehydratase large subunit low > 109
Pseudomonas fluorescens SBW25-INTG 0.27 PFLU_RS20515 amidophosphoribosyltransferase 0.65 PFLU_RS20580 3-isopropylmalate dehydratase large subunit 0.62 4
Pseudomonas simiae WCS417 0.27 PS417_18535 amidophosphoribosyltransferase 0.65 PS417_18600 isopropylmalate isomerase
Xanthomonas campestris pv. campestris strain 8004 0.27 Xcc-8004.4073.1 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.65 Xcc-8004.1049.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.71 37
Pseudomonas stutzeri RCH2 0.27 Psest_2579 amidophosphoribosyltransferase 0.65 Psest_2591 3-isopropylmalate dehydratase, large subunit 0.65 20
Pseudomonas sp. RS175 0.27 PFR28_02811 Amidophosphoribosyltransferase 0.66 PFR28_02824 3-isopropylmalate dehydratase large subunit 0.70 8
Pseudomonas fluorescens FW300-N2C3 0.27 AO356_21465 amidophosphoribosyltransferase 0.66 AO356_21400 isopropylmalate isomerase 0.78 24
Pseudomonas syringae pv. syringae B728a ΔmexB 0.27 Psyr_1668 amidophosphoribosyltransferase 0.65 Psyr_1983 3-isopropylmalate dehydratase, large subunit 0.87 8
Pseudomonas syringae pv. syringae B728a 0.27 Psyr_1668 amidophosphoribosyltransferase 0.65 Psyr_1983 3-isopropylmalate dehydratase, large subunit 0.83 6
Pseudomonas putida KT2440 0.27 PP_2000 amidophosphoribosyl transferase 0.65 PP_1985 3-isopropylmalate dehydratase large subunit 0.30 43
Pseudomonas fluorescens FW300-N2E3 0.27 AO353_20690 amidophosphoribosyltransferase 0.66 AO353_20620 isopropylmalate isomerase
Pseudomonas fluorescens GW456-L13 0.27 PfGW456L13_3935 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.66 PfGW456L13_3948 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Pseudomonas fluorescens FW300-N2E2 0.27 Pf6N2E2_76 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.66 Pf6N2E2_63 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
Cupriavidus basilensis FW507-4G11 0.27 RR42_RS14325 amidophosphoribosyltransferase 0.67 RR42_RS14400 isopropylmalate isomerase
Marinobacter adhaerens HP15 0.27 HP15_1821 amidophosphoribosyltransferase 0.67 HP15_1834 protein containing 3-isopropylmalate dehydratase, large subunit region domain
Ralstonia sp. UNC404CL21Col 0.26 ABZR87_RS14465 amidophosphoribosyltransferase 0.68 ABZR87_RS14540 3-isopropylmalate dehydratase large subunit
Castellaniella sp019104865 MT123 0.26 ABCV34_RS04130 amidophosphoribosyltransferase 0.67 ABCV34_RS04290 3-isopropylmalate dehydratase large subunit
Acinetobacter radioresistens SK82 0.25 MPMX26_01122 Amidophosphoribosyltransferase 0.65 MPMX26_00345 3-isopropylmalate dehydratase large subunit 0.84 29

Not shown: 1 genomes with orthologs for SMc00554 only; 11 genomes with orthologs for SMc03823 only