Conservation of cofitness between GFF651 and GFF4211 in Hydrogenophaga sp. GW460-11-11-14-LB1

94 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Hydrogenophaga sp. GW460-11-11-14-LB1 1.0 GFF651 Aspartate carbamoyltransferase (EC 2.1.3.2) 1.0 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.97 2
Variovorax sp. OAS795 0.90 ABID97_RS24660 aspartate carbamoyltransferase catalytic subunit 0.74 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase — —
Variovorax sp. SCN45 0.89 GFF2160 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.73 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) — —
Acidovorax sp. GW101-3H11 0.89 Ac3H11_3978 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.74 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Ralstonia solanacearum GMI1000 0.82 RS_RS03410 aspartate carbamoyltransferase 0.55 RS_RS08160 dihydroorotate dehydrogenase (quinone) — —
Cupriavidus basilensis FW507-4G11 0.82 RR42_RS15860 aspartate carbamoyltransferase catalytic subunit 0.53 RR42_RS07465 dihydroorotate dehydrogenase — —
Ralstonia solanacearum PSI07 0.82 RPSI07_RS20635 aspartate carbamoyltransferase catalytic subunit 0.55 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase — —
Paraburkholderia bryophila 376MFSha3.1 0.81 H281DRAFT_04817 aspartate carbamoyltransferase 0.51 H281DRAFT_00743 dihydroorotate oxidase A — —
Ralstonia solanacearum IBSBF1503 0.81 RALBFv3_RS12625 aspartate carbamoyltransferase catalytic subunit 0.55 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase — —
Paraburkholderia graminis OAS925 0.81 ABIE53_001131 aspartate carbamoyltransferase catalytic subunit 0.53 ABIE53_001954 dihydroorotate dehydrogenase — —
Ralstonia solanacearum UW163 0.81 UW163_RS00940 aspartate carbamoyltransferase catalytic subunit 0.55 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia sp. UNC404CL21Col 0.81 ABZR87_RS08625 aspartate carbamoyltransferase catalytic subunit 0.56 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase — —
Burkholderia phytofirmans PsJN 0.81 BPHYT_RS04235 aspartate carbamoyltransferase 0.53 BPHYT_RS08565 dihydroorotate dehydrogenase 0.30 11
Paraburkholderia sabiae LMG 24235 0.81 QEN71_RS25780 aspartate carbamoyltransferase catalytic subunit 0.53 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase — —
Herbaspirillum seropedicae SmR1 0.80 HSERO_RS02330 aspartate carbamoyltransferase 0.55 HSERO_RS16155 dihydroorotate dehydrogenase — —
Dechlorosoma suillum PS 0.76 Dsui_0596 aspartate carbamoyltransferase 0.51 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 — —
Pseudomonas stutzeri RCH2 0.66 Psest_0291 aspartate carbamoyltransferase 0.48 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 — —
Pseudomonas sp. S08-1 0.66 OH686_10940 aspartate carbamoyltransferase 0.46 OH686_03120 dihydroorotate dehydrogenase (fumarate) — —
Pseudomonas putida KT2440 0.66 PP_4998 Aspartate carbamoyltransferase 0.48 PP_2095 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas simiae WCS417 0.65 PS417_26700 aspartate carbamoyltransferase catalytic subunit 0.48 PS417_20935 dihydroorotate dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.65 PFLU_RS28345 aspartate carbamoyltransferase 0.48 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens GW456-L13 0.65 PfGW456L13_1016 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.48 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens SBW25 0.65 PFLU_RS28345 aspartate carbamoyltransferase 0.48 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens FW300-N2C3 0.65 AO356_13450 aspartate carbamoyltransferase catalytic subunit 0.47 AO356_02610 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas fluorescens FW300-N2E3 0.65 AO353_08135 aspartate carbamoyltransferase catalytic subunit 0.47 AO353_00780 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas fluorescens FW300-N2E2 0.65 Pf6N2E2_4606 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.47 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens FW300-N1B4 0.65 Pf1N1B4_2347 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.47 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.65 Psyr_0482 aspartate carbamoyltransferase 0.49 Psyr_2106 dihydroorotate oxidase A — —
Pseudomonas sp. RS175 0.65 PFR28_04237 Aspartate carbamoyltransferase 0.48 PFR28_01054 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas syringae pv. syringae B728a 0.65 Psyr_0482 aspartate carbamoyltransferase 0.49 Psyr_2106 dihydroorotate oxidase A — —
Marinobacter adhaerens HP15 0.62 HP15_3507 aspartate carbamoyltransferase 0.45 HP15_1377 dihydroorotate dehydrogenase 0.75 6
Acinetobacter radioresistens SK82 0.59 MPMX26_01099 Aspartate carbamoyltransferase 0.47 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) 0.97 2
Sinorhizobium meliloti 1021 0.49 SMc01360 aspartate carbamoyltransferase catalytic subunit 0.37 SMc02245 dihydroorotate dehydrogenase 2 0.88 4
Rhodospirillum rubrum S1H 0.49 Rru_A3190 Aspartate carbamoyltransferase (NCBI) 0.33 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) 0.70 3
Rhizobium sp. OAE497 0.47 ABIE40_RS07385 aspartate carbamoyltransferase catalytic subunit 0.35 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase — —
Magnetospirillum magneticum AMB-1 0.47 AMB_RS18300 aspartate carbamoyltransferase 0.32 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase — —
Agrobacterium fabrum C58 0.47 Atu1308 aspartate carbamoyl transferase catalytic subunit 0.39 Atu0486 dihydroorotate dehydrogenase 0.93 3
Azospirillum sp. SherDot2 0.47 MPMX19_01054 Aspartate carbamoyltransferase 0.35 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) — —
Bosea sp. OAE506 0.46 ABIE41_RS17230 aspartate carbamoyltransferase catalytic subunit 0.32 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase 0.77 2
Azospirillum brasilense Sp245 0.46 AZOBR_RS20575 aspartate carbamoyltransferase 0.36 AZOBR_RS13520 dihydroorotate dehydrogenase 0.67 2
Xanthomonas campestris pv. campestris strain 8004 0.46 Xcc-8004.1722.1 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.46 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Brevundimonas sp. GW460-12-10-14-LB2 0.46 A4249_RS04260 aspartate carbamoyltransferase catalytic subunit 0.34 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase — —
Lysobacter sp. OAE881 0.45 ABIE51_RS16015 aspartate carbamoyltransferase catalytic subunit 0.46 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.45 TX73_016120 aspartate carbamoyltransferase catalytic subunit 0.30 TX73_004110 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.44 LRK54_RS04220 aspartate carbamoyltransferase catalytic subunit 0.44 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans MT42 0.44 LRK55_RS03990 aspartate carbamoyltransferase catalytic subunit 0.45 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter sp. FW510-T8 0.44 OKGIIK_11095 pyrB aspartate carbamoyltransferase catalytic subunit 0.44 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Dinoroseobacter shibae DFL-12 0.44 Dshi_3091 aspartate carbamoyltransferase (RefSeq) 0.33 Dshi_0847 Dihydroorotate oxidase (RefSeq) 0.88 4
Dyella japonica UNC79MFTsu3.2 0.44 ABZR86_RS10390 aspartate carbamoyltransferase catalytic subunit 0.46 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.43 Echvi_4661 aspartate carbamoyltransferase 0.40 Echvi_1806 dihydroorotate dehydrogenase, subfamily 2 — —
Phaeobacter inhibens DSM 17395 0.43 PGA1_c03060 aspartate carbamoyltransferase PyrB 0.35 PGA1_c12150 dihydroorotate dehydrogenase PyrD 0.95 3
Caulobacter crescentus NA1000 Δfur 0.43 CCNA_02525 aspartate carbamoyltransferase 0.32 CCNA_00562 dihydroorotate dehydrogenase 0.61 29
Caulobacter crescentus NA1000 0.43 CCNA_02525 aspartate carbamoyltransferase 0.32 CCNA_00562 dihydroorotate dehydrogenase 0.95 5
Mucilaginibacter yixingensis YX-36 DSM 26809 0.43 ABZR88_RS03460 aspartate carbamoyltransferase catalytic subunit 0.37 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase — —
Pedobacter sp. GW460-11-11-14-LB5 0.43 CA265_RS14660 aspartate carbamoyltransferase 0.37 CA265_RS14005 dihydroorotate dehydrogenase (quinone) — —
Sphingomonas koreensis DSMZ 15582 0.42 Ga0059261_0076 aspartate carbamoyltransferase (EC 2.1.3.2) 0.34 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.41 CA264_20465 aspartate carbamoyltransferase 0.38 CA264_00865 dihydroorotate dehydrogenase (quinone) low > 74
Mycobacterium tuberculosis H37Rv 0.40 Rv1380 Probable aspartate carbamoyltransferase PyrB (ATCase) (aspartate transcarbamylase) 0.27 Rv2139 Probable dihydroorotate dehydrogenase PyrD — —
Synechococcus elongatus PCC 7942 0.39 Synpcc7942_0670 pyrB aspartate carbamoyltransferase catalytic subunit 0.30 Synpcc7942_0290 pyrD dihydroorotate dehydrogenase 2 — —
Methanococcus maripaludis JJ 0.23 MMJJ_RS05825 aspartate carbamoyltransferase 0.10 MMJJ_RS02945 dihydroorotate dehydrogenase — —
Methanococcus maripaludis S2 0.23 MMP_RS08545 aspartate carbamoyltransferase 0.10 MMP_RS02330 dihydroorotate dehydrogenase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.22 GFF930 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.44 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.58 9
Escherichia coli ECOR27 0.21 NOLOHH_04125 pyrB aspartate carbamoyltransferase 0.44 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase low > 57
Bacteroides thetaiotaomicron VPI-5482 0.21 BT0742 aspartate carbamoyltransferase catalytic chain (NCBI ptt file) 0.27 BT1009 dihydroorotate dehydrogenase (NCBI ptt file) — —
Escherichia coli ECRC62 0.21 BNILDI_07385 pyrB aspartate carbamoyltransferase 0.44 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia fergusonii Becca 0.21 EFB2_04288 Aspartate carbamoyltransferase catalytic subunit 0.44 EFB2_03126 Dihydroorotate dehydrogenase (quinone) low > 86
Escherichia coli ECRC102 0.21 NIAGMN_09715 pyrB aspartate carbamoyltransferase 0.44 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC101 0.21 MCAODC_02370 pyrB aspartate carbamoyltransferase 0.44 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Vibrio cholerae E7946 ATCC 55056 0.21 CSW01_12725 aspartate carbamoyltransferase 0.46 CSW01_07490 dihydroorotate dehydrogenase (quinone) 0.68 17
Escherichia coli ECRC99 0.21 KEDOAH_16290 pyrB aspartate carbamoyltransferase 0.44 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC98 0.21 JDDGAC_15505 pyrB aspartate carbamoyltransferase 0.44 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli BL21 0.21 ECD_04113 aspartate carbamoyltransferase, catalytic subunit 0.44 ECD_00949 dihydro-orotate oxidase, FMN-linked 0.76 8
Escherichia coli BW25113 0.21 b4245 pyrB aspartate carbamoyltransferase catalytic subunit (NCBI) 0.44 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 0.94 1
Escherichia coli ECOR38 0.21 HEPCGN_10060 pyrB aspartate carbamoyltransferase 0.44 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase low > 85
Escherichia coli ECRC101 0.21 OKFHMN_11865 pyrB aspartate carbamoyltransferase 0.44 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Enterobacter asburiae PDN3 0.21 EX28DRAFT_3446 aspartate carbamoyltransferase (EC 2.1.3.2) 0.45 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.21 OHPLBJKB_03789 Aspartate carbamoyltransferase catalytic subunit 0.44 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) 0.75 6
Escherichia coli Nissle 1917 0.21 ECOLIN_RS24625 aspartate carbamoyltransferase 0.44 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase — —
Pantoea sp. MT58 0.20 IAI47_16860 aspartate carbamoyltransferase 0.48 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.98 4
Enterobacter sp. TBS_079 0.20 MPMX20_00544 Aspartate carbamoyltransferase catalytic subunit 0.45 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.96 1
Kangiella aquimarina DSM 16071 0.20 B158DRAFT_0021 aspartate carbamoyltransferase (EC 2.1.3.2) 0.46 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) — —
Dickeya dadantii 3937 0.20 DDA3937_RS01925 aspartate carbamoyltransferase 0.46 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.91 3
Dickeya dianthicola ME23 0.20 DZA65_RS01970 aspartate carbamoyltransferase 0.46 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.95 2
Dickeya dianthicola 67-19 0.20 HGI48_RS01900 aspartate carbamoyltransferase 0.46 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.87 1
Klebsiella michiganensis M5al 0.20 BWI76_RS02995 aspartate carbamoyltransferase 0.45 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.92 1
Serratia liquefaciens MT49 0.20 IAI46_02275 aspartate carbamoyltransferase 0.46 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.81 9
Bifidobacterium breve UCC2003 0.20 BBR_RS15425 aspartate carbamoyltransferase 0.18 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase low > 34
Erwinia tracheiphila SCR3 0.20 LU632_RS20950 pyrB aspartate carbamoyltransferase 0.46 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.96 3
Rahnella sp. WP5 0.19 EX31_RS12785 aspartate carbamoyltransferase 0.46 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.94 6
Pectobacterium carotovorum WPP14 0.19 HER17_RS19510 aspartate carbamoyltransferase 0.47 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.97 16
Shewanella oneidensis MR-1 0.19 SO1301 pyrB aspartate carbamoyltransferase (NCBI ptt file) 0.47 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) 0.95 2
Shewanella sp. ANA-3 0.19 Shewana3_3070 aspartate carbamoyltransferase (RefSeq) 0.47 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.96 1
Alteromonas macleodii MIT1002 0.19 MIT1002_00423 Aspartate carbamoyltransferase catalytic chain 0.49 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) 0.87 40
Shewanella loihica PV-4 0.18 Shew_1013 aspartate carbamoyltransferase (RefSeq) 0.48 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) 0.90 6
Shewanella amazonensis SB2B 0.18 Sama_0840 aspartate carbamoyltransferase (RefSeq) 0.46 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) 0.89 3

Not shown: 8 genomes with orthologs for GFF651 only; 1 genomes with orthologs for GFF4211 only