Conservation of cofitness between CSW01_02425 and CSW01_05755 in Vibrio cholerae E7946 ATCC 55056

101 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02425 YggW family oxidoreductase 1.0 CSW01_05755 histidinol-phosphate transaminase 0.52 19
Pectobacterium carotovorum WPP14 0.69 HER17_RS03785 radical SAM family heme chaperone HemW 0.60 HER17_RS12235 histidinol-phosphate transaminase low > 75
Dickeya dadantii 3937 0.68 DDA3937_RS17325 radical SAM family heme chaperone HemW 0.60 DDA3937_RS09730 histidinol-phosphate transaminase low > 74
Dickeya dianthicola 67-19 0.68 HGI48_RS17370 radical SAM family heme chaperone HemW 0.60 HGI48_RS09740 histidinol-phosphate transaminase low > 71
Dickeya dianthicola ME23 0.68 DZA65_RS18460 radical SAM family heme chaperone HemW 0.60 DZA65_RS10050 histidinol-phosphate transaminase low > 75
Serratia liquefaciens MT49 0.68 IAI46_21435 radical SAM family heme chaperone HemW 0.59 IAI46_08205 histidinol-phosphate transaminase 0.54 25
Escherichia coli ECRC99 0.67 KEDOAH_08905 hemW radical SAM family heme chaperone HemW 0.59 KEDOAH_03640 hisC histidinol-phosphate transaminase
Escherichia coli ECRC101 0.67 MCAODC_09755 hemW radical SAM family heme chaperone HemW 0.59 MCAODC_20430 hisC histidinol-phosphate transaminase low > 87
Escherichia coli ECRC98 0.67 JDDGAC_22865 hemW radical SAM family heme chaperone HemW 0.59 JDDGAC_28620 hisC histidinol-phosphate transaminase low > 86
Escherichia coli ECRC100 0.67 OKFHMN_19235 hemW radical SAM family heme chaperone HemW 0.59 OKFHMN_24510 hisC histidinol-phosphate transaminase low > 80
Escherichia coli ECRC102 0.67 NIAGMN_17000 hemW radical SAM family heme chaperone HemW 0.59 NIAGMN_22455 hisC histidinol-phosphate transaminase
Escherichia fergusonii Becca 0.66 EFB2_00947 Heme chaperone HemW 0.59 EFB2_01835 Histidinol-phosphate aminotransferase low > 86
Escherichia coli BW25113 0.66 b2955 yggW coproporphyrinogen III oxidase (NCBI) 0.60 b2021 hisC histidinol-phosphate aminotransferase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.66 OHPLBJKB_00761 Oxygen-independent coproporphyrinogen-III oxidase-like protein YqeR 0.59 OHPLBJKB_01679 Histidinol-phosphate aminotransferase low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.66 GFF3058 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.57 GFF3911 Histidinol-phosphate aminotransferase (EC 2.6.1.9) low > 78
Escherichia coli BL21 0.66 ECD_02785 HemN family putative oxidoreductase 0.59 ECD_01923 histidinol-phosphate aminotransferase low > 61
Erwinia tracheiphila SCR3 0.66 LU632_RS05445 hemW radical SAM family heme chaperone HemW 0.57 LU632_RS08940 hisC histidinol-phosphate transaminase low > 74
Escherichia coli ECRC62 0.66 BNILDI_09685 hemW radical SAM family heme chaperone HemW 0.60 BNILDI_14735 hisC histidinol-phosphate transaminase low > 75
Escherichia coli ECOR38 0.65 HEPCGN_18540 hemW radical SAM family heme chaperone HemW 0.59 HEPCGN_03215 hisC histidinol-phosphate transaminase low > 87
Escherichia coli Nissle 1917 0.65 ECOLIN_RS16435 radical SAM family heme chaperone HemW 0.59 ECOLIN_RS11950 histidinol-phosphate transaminase
Escherichia coli ECOR27 0.65 NOLOHH_11105 hemW radical SAM family heme chaperone HemW 0.60 NOLOHH_15825 hisC histidinol-phosphate transaminase low > 75
Enterobacter sp. TBS_079 0.65 MPMX20_03813 Heme chaperone HemW 0.58 MPMX20_03003 Histidinol-phosphate aminotransferase low > 85
Enterobacter asburiae PDN3 0.65 EX28DRAFT_2993 putative oxygen-independent coproporphyrinogen III oxidase 0.57 EX28DRAFT_0538 histidinol-phosphate aminotransferase low > 76
Pantoea sp. MT58 0.65 IAI47_03580 radical SAM family heme chaperone HemW 0.58 IAI47_07085 histidinol-phosphate transaminase low > 76
Klebsiella michiganensis M5al 0.65 BWI76_RS24120 YggW family oxidoreductase 0.59 BWI76_RS18930 histidinol-phosphate transaminase low > 92
Erwinia amylovora T8 0.64 OLJFJH_08515 radical SAM family heme chaperone HemW 0.58 OLJFJH_12175 histidinol-phosphate transaminase low > 58
Rahnella sp. WP5 0.63 EX31_RS02710 radical SAM family heme chaperone HemW 0.57 EX31_RS11445 histidinol-phosphate transaminase low > 89
Shewanella loihica PV-4 0.59 Shew_1131 putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) 0.42 Shew_2199 histidinol-phosphate aminotransferase (RefSeq) low > 60
Shewanella sp. ANA-3 0.59 Shewana3_1188 putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) 0.46 Shewana3_1852 histidinol phosphate aminotransferase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.59 SO3359 oxygen-independent coproporphyrinogen III oxidase, putative (NCBI ptt file) 0.46 SO2072 hisC histidinol-phosphate aminotransferase (NCBI ptt file) low > 76
Alteromonas macleodii MIT1002 0.59 MIT1002_00939 Oxygen-independent coproporphyrinogen-III oxidase 1 0.47 MIT1002_02634 Histidinol-phosphate aminotransferase low > 70
Shewanella amazonensis SB2B 0.56 Sama_2483 oxygen-independent coproporphyrinogen III oxidase, putative (RefSeq) 0.35 Sama_1943 histidinol-phosphate aminotransferase (RefSeq) low > 62
Pseudomonas sp. RS175 0.54 PFR28_04249 Heme chaperone HemW 0.17 PFR28_00908 Histidinol-phosphate aminotransferase 0.27 53
Kangiella aquimarina DSM 16071 0.54 B158DRAFT_0201 coproporphyrinogen III oxidase, anaerobic (EC 1.3.99.22) 0.20 B158DRAFT_2325 histidinol-phosphate aminotransferase low > 40
Pseudomonas fluorescens FW300-N2E2 0.54 Pf6N2E2_4593 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.18 Pf6N2E2_2519 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) low > 103
Pseudomonas fluorescens FW300-N2E3 0.53 AO353_08200 coproporphyrinogen III oxidase 0.18 AO353_02065 aspartate aminotransferase low > 101
Pseudomonas fluorescens GW456-L13 0.53 PfGW456L13_1003 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.18 PfGW456L13_2177 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) low > 87
Pseudomonas simiae WCS417 0.53 PS417_26760 oxidase 0.18 PS417_08130 aspartate aminotransferase low > 88
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS28405 radical SAM family heme chaperone HemW 0.18 PFLU_RS08100 histidinol-phosphate transaminase low > 109
Pseudomonas fluorescens SBW25 0.53 PFLU_RS28405 radical SAM family heme chaperone HemW 0.18 PFLU_RS08100 histidinol-phosphate transaminase low > 109
Pseudomonas fluorescens FW300-N1B4 0.53 Pf1N1B4_2334 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.17 Pf1N1B4_349 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) low > 87
Pseudomonas sp. DMC3 0.53 GFF216 Heme chaperone HemW 0.18 GFF4676 Histidinol-phosphate aminotransferase low > 89
Pseudomonas fluorescens FW300-N2C3 0.53 AO356_13390 coproporphyrinogen III oxidase 0.18 AO356_03460 aspartate aminotransferase low > 104
Pseudomonas sp. SVBP6 0.52 COO64_RS12965 hemW radical SAM family heme chaperone HemW 0.15 COO64_RS04360 hisC histidinol-phosphate transaminase low > 93
Pseudomonas aeruginosa PA14 0.51 IKLFDK_23495 radical SAM family heme chaperone HemW 0.17 IKLFDK_16085 histidinol-phosphate transaminase low > 101
Pseudomonas sp. BP01 0.51 JOY50_RS20875 hemW radical SAM family heme chaperone HemW 0.15 JOY50_RS11205 hisC histidinol-phosphate transaminase low > 84
Pseudomonas putida KT2440 0.51 PP_5101 coproporphyrinogen/heterocyclic compound oxidase (aerobic) 0.15 PP_0967 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) low > 96
Pseudomonas sp. S08-1 0.51 OH686_11020 Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW 0.17 OH686_20875 histidinol-phosphate transaminase low > 80
Pseudomonas stutzeri RCH2 0.50 Psest_0276 putative oxygen-independent coproporphyrinogen III oxidase 0.19 Psest_1985 histidinol-phosphate aminotransferase low > 67
Pseudomonas syringae pv. syringae B728a 0.50 Psyr_0471 coproporphyrinogen III oxidase, anaerobic 0.16 Psyr_4132 histidinol phosphate aminotransferase apoenzyme low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.50 Psyr_0471 coproporphyrinogen III oxidase, anaerobic 0.16 Psyr_4132 histidinol phosphate aminotransferase apoenzyme low > 86
Xanthomonas campestris pv. campestris strain 8004 0.48 Xcc-8004.1224.1 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.37 Xcc-8004.2947.1 Histidinol-phosphate aminotransferase (EC 2.6.1.9) low > 74
Dyella japonica UNC79MFTsu3.2 0.47 ABZR86_RS11910 radical SAM family heme chaperone HemW 0.31 ABZR86_RS06725 histidinol-phosphate transaminase low > 74
Lysobacter sp. OAE881 0.47 ABIE51_RS17300 radical SAM family heme chaperone HemW 0.32 ABIE51_RS13320 histidinol-phosphate transaminase low > 62
Rhodanobacter sp000427505 FW510-R12 0.46 LRK53_RS16820 radical SAM family heme chaperone HemW 0.38 LRK53_RS08465 histidinol-phosphate transaminase low > 60
Rhodanobacter denitrificans MT42 0.46 LRK55_RS11460 radical SAM family heme chaperone HemW 0.35 LRK55_RS01380 histidinol-phosphate transaminase low > 63
Rhodanobacter denitrificans FW104-10B01 0.46 LRK54_RS11735 radical SAM family heme chaperone HemW 0.36 LRK54_RS01600 histidinol-phosphate transaminase low > 59
Cupriavidus basilensis FW507-4G11 0.45 RR42_RS04880 coproporphyrinogen III oxidase 0.17 RR42_RS18910 histidinol-phosphate aminotransferase
Paraburkholderia bryophila 376MFSha3.1 0.45 H281DRAFT_04010 oxygen-independent coproporphyrinogen-3 oxidase 0.18 H281DRAFT_05654 histidinol phosphate aminotransferase apoenzyme low > 103
Burkholderia phytofirmans PsJN 0.44 BPHYT_RS15335 coproporphyrinogen III oxidase 0.18 BPHYT_RS14905 Aromatic-amino-acid transaminase (EC 2.6.1.57) (from data) low > 109
Rhodanobacter sp. FW510-T8 0.44 OKGIIK_12160 hemW radical SAM family heme chaperone HemW 0.37 OKGIIK_04955 hisC histidinol-phosphate transaminase low > 52
Herbaspirillum seropedicae SmR1 0.44 HSERO_RS10665 coproporphyrinogen III oxidase 0.20 HSERO_RS20335 histidinol-phosphate aminotransferase low > 78
Dechlorosoma suillum PS 0.44 Dsui_0491 putative oxygen-independent coproporphyrinogen III oxidase 0.17 Dsui_1414 histidinol-phosphate aminotransferase
Paraburkholderia graminis OAS925 0.44 ABIE53_003236 putative oxygen-independent coproporphyrinogen III oxidase 0.18 ABIE53_003700 histidinol-phosphate aminotransferase low > 113
Variovorax sp. OAS795 0.44 ABID97_RS23630 radical SAM family heme chaperone HemW 0.19 ABID97_RS23145 histidinol-phosphate transaminase low > 91
Paraburkholderia sabiae LMG 24235 0.44 QEN71_RS03635 radical SAM family heme chaperone HemW 0.19 QEN71_RS27860 histidinol-phosphate transaminase low > 153
Variovorax sp. SCN45 0.44 GFF2383 Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW 0.19 GFF5348 Histidinol-phosphate aminotransferase (EC 2.6.1.9) low > 127
Ralstonia solanacearum PSI07 0.44 RPSI07_RS13830 oxygen-independent coproporphyrinogen III oxidase-like protein 0.17 RPSI07_RS19705 histidinol-phosphate transaminase low > 81
Marinobacter adhaerens HP15 0.43 HP15_280 putative oxygen-independent coproporphyrinogen III oxidase 0.17 HP15_1363 histidinol-phosphate aminotransferase low > 73
Methylophilus sp. DMC18 0.43 GFF2148 Heme chaperone HemW 0.19 GFF666 Histidinol-phosphate aminotransferase
Ralstonia sp. UNC404CL21Col 0.43 ABZR87_RS15265 radical SAM family heme chaperone HemW 0.17 ABZR87_RS03260 histidinol-phosphate transaminase low > 80
Ralstonia solanacearum GMI1000 0.42 RS_RS10840 oxygen-independent coproporphyrinogen III oxidase-like protein 0.17 RS_RS14785 histidinol-phosphate aminotransferase 1
Ralstonia solanacearum IBSBF1503 0.42 RALBFv3_RS03355 oxygen-independent coproporphyrinogen III oxidase-like protein 0.18 RALBFv3_RS13765 histidinol-phosphate transaminase low > 76
Ralstonia solanacearum UW163 0.42 UW163_RS10365 oxygen-independent coproporphyrinogen III oxidase-like protein 0.18 UW163_RS16045 histidinol-phosphate transaminase
Hydrogenophaga sp. GW460-11-11-14-LB1 0.42 GFF3256 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.19 GFF1313 Histidinol-phosphate aminotransferase (EC 2.6.1.9) low > 90
Acinetobacter radioresistens SK82 0.41 MPMX26_00308 Heme chaperone HemW 0.17 MPMX26_02586 Histidinol-phosphate aminotransferase low > 36
Acidovorax sp. GW101-3H11 0.41 Ac3H11_3672 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB 0.17 Ac3H11_4729 histidinol-phosphate transaminase (EC 2.6.1.9) (from data)
Castellaniella sp019104865 MT123 0.41 ABCV34_RS03525 radical SAM family heme chaperone HemW 0.17 ABCV34_RS02645 histidinol-phosphate transaminase low > 48
Rhodopseudomonas palustris CGA009 0.31 TX73_001700 radical SAM family heme chaperone HemW 0.14 TX73_023035 histidinol-phosphate transaminase
Rhizobium sp. OAE497 0.30 ABIE40_RS01625 radical SAM family heme chaperone HemW 0.14 ABIE40_RS17595 histidinol-phosphate transaminase
Agrobacterium fabrum C58 0.30 Atu0325 oxygen-independent coproporphyrinogen III oxidase 0.13 Atu3612 histidinol-phosphate aminotransferase
Sinorhizobium meliloti 1021 0.29 SMc01147 coproporphyrinogen III oxidase 0.15 SMc03885 histidinol-phosphate aminotransferase low > 103
Azospirillum sp. SherDot2 0.29 MPMX19_02574 Heme chaperone HemW 0.15 MPMX19_04389 Histidinol-phosphate aminotransferase
Azospirillum brasilense Sp245 0.29 AZOBR_RS02195 coproporphyrinogen III oxidase 0.17 AZOBR_RS20485 histidinol-phosphate aminotransferase [EC:2.6.1.9] (from data) low > 97
Rhodospirillum rubrum S1H 0.29 Rru_A3639 Putative oxygen-independent coproporphyrinogen III oxidase (NCBI) 0.17 Rru_A3264 Histidinol-phosphate aminotransferase (NCBI) low > 58
Phaeobacter inhibens DSM 17395 0.28 PGA1_c35050 oxygen-independent coproporphyrinogen III oxidase HemN 0.15 PGA1_c25240 histidinol-phosphate aminotransferase [EC:2.6.1.9] (from data)
Dinoroseobacter shibae DFL-12 0.28 Dshi_3460 putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) 0.13 Dshi_2946 histidinol-phosphate aminotransferase (RefSeq)
Magnetospirillum magneticum AMB-1 0.27 AMB_RS22770 radical SAM protein 0.15 AMB_RS20110 histidinol-phosphate aminotransferase
Xanthobacter sp. DMC5 0.27 GFF1891 hypothetical protein 0.12 GFF4390 Histidinol-phosphate aminotransferase
Caulobacter crescentus NA1000 0.26 CCNA_00144 oxygen-independent coproporphyrinogen-III oxidase 0.16 CCNA_01124 histidinol-phosphate aminotransferase low > 66
Caulobacter crescentus NA1000 Δfur 0.26 CCNA_00144 oxygen-independent coproporphyrinogen-III oxidase 0.16 CCNA_01124 histidinol-phosphate aminotransferase low > 67
Brevundimonas sp. GW460-12-10-14-LB2 0.26 A4249_RS12445 radical SAM family heme chaperone HemW 0.13 A4249_RS11450 histidinol-phosphate transaminase low > 48
Fusobacterium nucleatum SB010 0.25 HUW76_07285 radical SAM family heme chaperone HemW 0.11 HUW76_05250 threonine-phosphate decarboxylase low > 35
Sphingomonas koreensis DSMZ 15582 0.25 Ga0059261_2753 putative oxygen-independent coproporphyrinogen III oxidase 0.14 Ga0059261_2299 histidinol-phosphate aminotransferase low > 68
Desulfovibrio vulgaris Miyazaki F 0.24 DvMF_2374 oxygen-independent coproporphyrinogen III oxidase (RefSeq) 0.19 DvMF_0908 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) low > 51
Mycobacterium tuberculosis H37Rv 0.24 Rv2388c Probable oxygen-independent coproporphyrinogen III oxidase HemN (coproporphyrinogenase) (coprogen oxidase) 0.16 Rv1600 Probable histidinol-phosphate aminotransferase HisC1
Echinicola vietnamensis KMM 6221, DSM 17526 0.24 Echvi_0628 putative oxygen-independent coproporphyrinogen III oxidase 0.31 Echvi_2458 histidinol-phosphate aminotransferase low > 79
Pontibacter actiniarum KMM 6156, DSM 19842 0.22 CA264_16765 coproporphyrinogen III oxidase 0.32 CA264_05035 histidinol-phosphate transaminase low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.21 ABZR88_RS03545 radical SAM family heme chaperone HemW 0.31 ABZR88_RS06875 histidinol-phosphate transaminase low > 71
Bacteroides stercoris CC31F 0.21 HMPREF1181_RS06440 radical SAM family heme chaperone HemW 0.29 HMPREF1181_RS04855 histidinol-phosphate transaminase low > 56
Bifidobacterium breve UCC2003 0.20 BBR_RS15235 coproporphyrinogen III oxidase 0.15 BBR_RS17050 histidinol-phosphate transaminase low > 34
Cellulophaga baltica 18 0.20 M666_RS07265 radical SAM family heme chaperone HemW 0.29 M666_RS17150 histidinol-phosphate transaminase low > 67

Not shown: 1 genomes with orthologs for CSW01_02425 only; 10 genomes with orthologs for CSW01_05755 only