Conservation of cofitness between BT0556 and BT2387 in Bacteroides thetaiotaomicron VPI-5482

98 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT0556 carbamoyl phosphate synthetase III (glutamine-hydrolyzing) (NCBI ptt file) 1.0 BT2387 O-acetylhomoserine (thiol)-lyase (NCBI ptt file) 0.72 17
Bacteroides ovatus ATCC 8483 0.90 BACOVA_03753 carbamoyl-phosphate synthase, small subunit 0.97 BACOVA_03030 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 94
Bacteroides stercoris CC31F 0.80 HMPREF1181_RS16070 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.88 HMPREF1181_RS05290 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 56
Phocaeicola vulgatus CL09T03C04 0.79 HMPREF1058_RS06875 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.93 HMPREF1058_RS17635 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 67
Phocaeicola dorei CL03T12C01 0.79 ABI39_RS20670 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.92 ABI39_RS13825 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 72
Parabacteroides merdae CL09T00C40 0.75 HMPREF1078_RS01295 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.76 HMPREF1078_RS07330 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 61
Fusobacterium nucleatum SB010 0.36 HUW76_08755 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.37 HUW76_08240 methionine gamma-lyase low > 35
Kangiella aquimarina DSM 16071 0.33 B158DRAFT_0615 carbamoyl-phosphate synthase, small subunit 0.34 B158DRAFT_1522 methionine gamma-lyase
Rhodanobacter denitrificans MT42 0.33 LRK55_RS17850 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.29 LRK55_RS05410 cystathionine gamma-synthase
Pseudomonas simiae WCS417 0.33 PS417_24045 carbamoyl phosphate synthase small subunit 0.34 PS417_18530 O-succinylhomoserine sulfhydrylase
Pseudomonas fluorescens SBW25-INTG 0.33 PFLU_RS25885 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.52 PFLU_RS02250 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase
Pseudomonas fluorescens SBW25 0.33 PFLU_RS25885 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.52 PFLU_RS02250 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase
Rhodanobacter denitrificans FW104-10B01 0.33 LRK54_RS17995 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.29 LRK54_RS05660 PLP-dependent aspartate aminotransferase family protein
Shewanella amazonensis SB2B 0.33 Sama_2504 carbamoyl phosphate synthase small subunit (RefSeq) 0.33 Sama_1242 methionine gamma-lyase (RefSeq) low > 62
Pseudomonas fluorescens FW300-N2C3 0.33 AO356_07485 carbamoyl phosphate synthase small subunit 0.34 AO356_21470 O-succinylhomoserine sulfhydrylase
Pseudomonas fluorescens FW300-N1B4 0.33 Pf1N1B4_1173 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) 0.29 Pf1N1B4_4890 Cystathionine gamma-lyase (EC 4.4.1.1)
Cupriavidus basilensis FW507-4G11 0.33 RR42_RS13520 carbamoyl phosphate synthase small subunit 0.54 RR42_RS32610 O-acetylhomoserine aminocarboxypropyltransferase
Pseudomonas fluorescens FW300-N2E2 0.33 Pf6N2E2_3365 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) 0.34 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Pseudomonas fluorescens FW300-N2E3 0.33 AO353_05635 carbamoyl phosphate synthase small subunit 0.33 AO353_20695 O-succinylhomoserine sulfhydrylase
Rhodanobacter sp. FW510-T8 0.33 OKGIIK_07300 carbamoyl phosphate synthase small subunit 0.29 OKGIIK_01180 metC cystathionine beta-lyase low > 52
Pseudomonas sp. RS175 0.32 PFR28_00076 Carbamoyl-phosphate synthase small chain 0.34 PFR28_02810 O-succinylhomoserine sulfhydrylase
Pseudomonas fluorescens GW456-L13 0.32 PfGW456L13_5100 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) 0.33 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Dechlorosoma suillum PS 0.32 Dsui_3065 carbamoyl-phosphate synthase, small subunit 0.57 Dsui_2241 OAH/OAS sulfhydrylase
Synechococcus elongatus PCC 7942 0.32 Synpcc7942_2122 carA carbamoyl phosphate synthase small subunit 0.49 Synpcc7942_0370 metY O-acetylhomoserine/O-acetylserine sulfhydrylase
Dyella japonica UNC79MFTsu3.2 0.32 ABZR86_RS05605 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.30 ABZR86_RS18745 PLP-dependent aspartate aminotransferase family protein
Xanthomonas campestris pv. campestris strain 8004 0.32 Xcc-8004.2914.1 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) 0.52 Xcc-8004.1385.1 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Pseudomonas putida KT2440 0.32 PP_4724 Carbamoyl-phosphate synthase small chain 0.55 PP_2528 O-acetylhomoserine (thiol)-lyase low > 96
Marinobacter adhaerens HP15 0.32 HP15_3078 carbamoyl-phosphate synthase small chain 0.56 HP15_641 homocysteine synthase low > 73
Shewanella loihica PV-4 0.32 Shew_2839 carbamoyl phosphate synthase small subunit (RefSeq) 0.49 Shew_2710 O-acetylhomoserine/O-acetylserine sulfhydrylase (RefSeq) low > 60
Pseudomonas syringae pv. syringae B728a ΔmexB 0.32 Psyr_4192 carbamoyl-phosphate synthase small subunit 0.35 Psyr_1669 O-succinylhomoserine sulfhydrylase
Pseudomonas syringae pv. syringae B728a 0.32 Psyr_4192 carbamoyl-phosphate synthase small subunit 0.35 Psyr_1669 O-succinylhomoserine sulfhydrylase
Klebsiella michiganensis M5al 0.32 BWI76_RS04465 carbamoyl-phosphate synthase small subunit 0.28 BWI76_RS16730 cystathionine gamma-lyase low > 92
Pectobacterium carotovorum WPP14 0.32 HER17_RS02895 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.51 HER17_RS17585 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme low > 75
Escherichia coli BW25113 0.32 b0032 carA carbamoyl-phosphate synthase small subunit (NCBI) 0.21 b3939 metB cystathionine gamma-synthase (NCBI) 0.80 67
Escherichia coli ECRC99 0.32 KEDOAH_17210 carA carbamoyl phosphate synthase small subunit 0.21 KEDOAH_14485 metB cystathionine gamma-synthase
Escherichia coli HS(pFamp)R (ATCC 700891) 0.32 OHPLBJKB_03625 Carbamoyl-phosphate synthase small chain 0.21 OHPLBJKB_04111 Cystathionine gamma-synthase low > 73
Escherichia coli ECRC62 0.32 BNILDI_08325 carA carbamoyl phosphate synthase small subunit 0.21 BNILDI_05715 metB cystathionine gamma-synthase
Escherichia coli ECOR38 0.32 HEPCGN_08930 carA carbamoyl phosphate synthase small subunit 0.23 HEPCGN_21950 cystathionine gamma-synthase low > 85
Azospirillum brasilense Sp245 0.32 AZOBR_RS10920 carbamoyl phosphate synthase small subunit 0.55 AZOBR_RS11340 O-acetylhomoserine aminocarboxypropyltransferase
Dickeya dadantii 3937 0.32 DDA3937_RS18310 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.23 DDA3937_RS00950 cystathionine gamma-synthase 0.80 28
Escherichia fergusonii Becca 0.32 EFB2_04013 Carbamoyl-phosphate synthase small chain 0.21 EFB2_04679 Cystathionine gamma-synthase low > 86
Escherichia coli ECRC102 0.32 NIAGMN_08795 carA carbamoyl phosphate synthase small subunit 0.21 NIAGMN_11430 metB cystathionine gamma-synthase
Escherichia coli ECOR27 0.32 NOLOHH_03275 carA carbamoyl phosphate synthase small subunit 0.21 NOLOHH_05820 metB cystathionine gamma-synthase low > 57
Escherichia coli Nissle 1917 0.32 ECOLIN_RS00175 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.22 ECOLIN_RS22725 cystathionine gamma-synthase low > 52
Escherichia coli ECRC101 0.32 MCAODC_01460 carA carbamoyl phosphate synthase small subunit 0.21 MCAODC_04175 metB cystathionine gamma-synthase
Escherichia coli ECRC98 0.32 JDDGAC_14540 carA carbamoyl phosphate synthase small subunit 0.21 JDDGAC_17300 metB cystathionine gamma-synthase
Escherichia coli ECRC101 0.32 OKFHMN_10945 carA carbamoyl phosphate synthase small subunit 0.21 OKFHMN_13675 metB cystathionine gamma-synthase
Escherichia coli BL21 0.32 ECD_00036 carbamoyl phosphate synthetase small subunit, glutamine amidotransferase 0.21 ECD_03825 cystathionine gamma-synthase, PLP-dependent low > 60
Shewanella sp. ANA-3 0.32 Shewana3_0967 carbamoyl phosphate synthase small subunit (RefSeq) 0.47 Shewana3_0930 O-acetylhomoserine/O-acetylserine sulfhydrylase (RefSeq) low > 73
Dickeya dianthicola 67-19 0.32 HGI48_RS18245 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.51 HGI48_RS15890 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 71
Dickeya dianthicola ME23 0.31 DZA65_RS19385 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.51 DZA65_RS16970 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 75
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.31 GFF214 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) 0.22 GFF2323 Cystathionine gamma-synthase (EC 2.5.1.48) low > 78
Azospirillum sp. SherDot2 0.31 MPMX19_00757 Carbamoyl-phosphate synthase small chain 0.54 MPMX19_00422 O-acetyl-L-homoserine sulfhydrylase
Shewanella oneidensis MR-1 0.31 SO1141 carA carbamoyl-phosphate synthase, small subunit (NCBI ptt file) 0.47 SO1095 O-acetylhomoserine (thiol)-lyase, putative (NCBI ptt file) low > 76
Enterobacter asburiae PDN3 0.31 EX28DRAFT_3637 carbamoyl-phosphate synthase, small subunit 0.25 EX28DRAFT_1678 Cystathionine beta-lyases/cystathionine gamma-synthases
Alteromonas macleodii MIT1002 0.31 MIT1002_01466 Carbamoyl-phosphate synthase small chain 0.26 MIT1002_02266 Methionine gamma-lyase 0.98 14
Pantoea sp. MT58 0.31 IAI47_16120 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.21 IAI47_00880 cystathionine gamma-synthase 0.89 11
Enterobacter sp. TBS_079 0.31 MPMX20_00739 Carbamoyl-phosphate synthase small chain 0.25 MPMX20_01953 Cystathionine beta-lyase low > 85
Vibrio cholerae E7946 ATCC 55056 0.31 CSW01_12105 carbamoyl-phosphate synthase small subunit 0.23 CSW01_13550 O-succinylhomoserine (thiol)-lyase low > 62
Paraburkholderia sabiae LMG 24235 0.31 QEN71_RS04775 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.51 QEN71_RS05200 O-acetylhomoserine aminocarboxypropyltransferase
Rahnella sp. WP5 0.31 EX31_RS03835 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.32 EX31_RS04985 PLP-dependent transferase low > 89
Herbaspirillum seropedicae SmR1 0.31 HSERO_RS06920 carbamoyl phosphate synthase small subunit 0.54 HSERO_RS18310 O-acetylhomoserine aminocarboxypropyltransferase
Acidovorax sp. GW101-3H11 0.31 Ac3H11_435 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) 0.55 Ac3H11_549 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Serratia liquefaciens MT49 0.31 IAI46_03190 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.33 IAI46_03630 methionine gamma-lyase low > 86
Lysobacter sp. OAE881 0.31 ABIE51_RS11625 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.28 ABIE51_RS04295 cystathionine gamma-synthase low > 62
Variovorax sp. OAS795 0.31 ABID97_RS17090 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.56 ABID97_RS15510 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
Pseudomonas sp. S08-1 0.31 OH686_17075 Carbamoyl-phosphate synthase small chain 0.56 OH686_09845 O-acetylhomoserine sulfhydrylase or O-succinylhomoserine sulfhydrylase
Erwinia tracheiphila SCR3 0.31 LU632_RS02755 carA glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.22 LU632_RS19640 metB cystathionine gamma-synthase low > 74
Castellaniella sp019104865 MT123 0.31 ABCV34_RS15505 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.55 ABCV34_RS10165 bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase
Paraburkholderia graminis OAS925 0.31 ABIE53_003005 carbamoyl-phosphate synthase small subunit 0.50 ABIE53_002919 O-acetylhomoserine (thiol)-lyase
Acinetobacter radioresistens SK82 0.31 MPMX26_00767 Carbamoyl-phosphate synthase small chain 0.55 MPMX26_02833 O-acetyl-L-homoserine sulfhydrylase low > 36
Variovorax sp. SCN45 0.31 GFF377 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) 0.56 GFF1255 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Pseudomonas stutzeri RCH2 0.30 Psest_0967 carbamoyl-phosphate synthase, small subunit 0.56 Psest_3685 OAH/OAS sulfhydrylase
Hydrogenophaga sp. GW460-11-11-14-LB1 0.30 GFF4899 Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) 0.55 GFF5041 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Pontibacter actiniarum KMM 6156, DSM 19842 0.30 CA264_19490 carbamoyl phosphate synthase small subunit 0.51 CA264_02370 O-acetylhomoserine aminocarboxypropyltransferase low > 74
Paraburkholderia bryophila 376MFSha3.1 0.30 H281DRAFT_04402 carbamoyl-phosphate synthase small subunit 0.50 H281DRAFT_04486 O-acetylhomoserine sulfhydrylase
Ralstonia solanacearum PSI07 0.30 RPSI07_RS15245 carbamoyl-phosphate synthase small subunit 0.50 RPSI07_RS15620 O-acetylhomoserine aminocarboxypropyltransferase
Ralstonia solanacearum IBSBF1503 0.30 RALBFv3_RS02200 carbamoyl-phosphate synthase small subunit 0.50 RALBFv3_RS01870 O-acetylhomoserine aminocarboxypropyltransferase
Ralstonia solanacearum UW163 0.30 UW163_RS15510 carbamoyl-phosphate synthase small subunit 0.50 UW163_RS15180 O-acetylhomoserine aminocarboxypropyltransferase
Burkholderia phytofirmans PsJN 0.30 BPHYT_RS14195 carbamoyl phosphate synthase small subunit 0.51 BPHYT_RS13720 O-acetylhomoserine aminocarboxypropyltransferase low > 109
Ralstonia sp. UNC404CL21Col 0.30 ABZR87_RS14150 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.56 ABZR87_RS17575 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme
Ralstonia solanacearum GMI1000 0.30 RS_RS07620 carbamoyl-phosphate synthase small subunit 0.50 RS_RS07865 O-acetylhomoserine aminocarboxypropyltransferase
Echinicola vietnamensis KMM 6221, DSM 17526 0.28 Echvi_0226 carbamoyl-phosphate synthase, small subunit 0.51 Echvi_3411 OAH/OAS sulfhydrylase
Rhodopseudomonas palustris CGA009 0.28 TX73_006555 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.54 TX73_008060 O-acetylhomoserine aminocarboxypropyltransferase
Magnetospirillum magneticum AMB-1 0.28 AMB_RS03600 carbamoyl-phosphate synthase small subunit 0.47 AMB_RS12895 O-acetylhomoserine aminocarboxypropyltransferase
Dinoroseobacter shibae DFL-12 0.28 Dshi_2387 carbamoyl-phosphate synthase, small subunit (RefSeq) 0.45 Dshi_0793 O-acetylhomoserine/O-acetylserine sulfhydrylase (RefSeq)
Bosea sp. OAE506 0.28 ABIE41_RS11975 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.50 ABIE41_RS19270 O-acetylhomoserine aminocarboxypropyltransferase
Phaeobacter inhibens DSM 17395 0.28 PGA1_c06670 carbamoyl-phosphate synthase small chain 0.45 PGA1_c07640 O-acetylhomoserine / O-acetylserine sulfhydrylase low > 62
Mycobacterium tuberculosis H37Rv 0.28 Rv1383 Probable carbamoyl-phosphate synthase small chain CarA (carbamoyl-phosphate synthetase glutamine chain) 0.53 Rv3340 Probable O-acetylhomoserine sulfhydrylase MetC (homocysteine synthase) (O-acetylhomoserine (thiol)-lyase) (OAH sulfhydrylase) (O-acetyl-L-homoserine sulfhydrylase)
Brevundimonas sp. GW460-12-10-14-LB2 0.27 A4249_RS16140 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.28 A4249_RS08315 cystathionine gamma-synthase
Sphingomonas koreensis DSMZ 15582 0.27 Ga0059261_4243 carbamoyl-phosphate synthase, small subunit 0.32 Ga0059261_3194 O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data)
Pedobacter sp. GW460-11-11-14-LB5 0.27 CA265_RS15240 carbamoyl phosphate synthase small subunit 0.50 CA265_RS08180 O-acetylhomoserine aminocarboxypropyltransferase
Rhizobium sp. OAE497 0.27 ABIE40_RS12765 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.56 ABIE40_RS07005 O-acetylhomoserine aminocarboxypropyltransferase
Agrobacterium fabrum C58 0.27 Atu2170 carbamoylphosphate synthase small chain 0.53 Atu1251 O-acetylhomoserine sulfhydrylase
Mucilaginibacter yixingensis YX-36 DSM 26809 0.27 ABZR88_RS17830 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit 0.28 ABZR88_RS06685 cystathionine gamma-synthase
Bifidobacterium breve UCC2003 0.27 BBR_RS13630 carbamoyl-phosphate synthase small subunit 0.72 BBR_RS14595 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 34
Caulobacter crescentus NA1000 Δfur 0.27 CCNA_02925 carbamoyl-phosphate synthase small chain 0.31 CCNA_03271 methionine gamma-lyase low > 67
Caulobacter crescentus NA1000 0.27 CCNA_02925 carbamoyl-phosphate synthase small chain 0.31 CCNA_03271 methionine gamma-lyase
Sinorhizobium meliloti 1021 0.27 SMc01569 carbamoyl phosphate synthase small subunit 0.54 SMc01809 O-acetylhomoserine aminocarboxypropyltransferase low > 103

Not shown: 5 genomes with orthologs for BT0556 only; 0 genomes with orthologs for BT2387 only