Conservation of cofitness between b0109 and b3771 in Escherichia coli BW25113

95 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0109 nadC nicotinate-nucleotide pyrophosphorylase (NCBI) 1.0 b3771 ilvD dihydroxy-acid dehydratase (NCBI) 0.65 14
Escherichia coli ECOR27 1.00 NOLOHH_02875 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 NOLOHH_06775 ilvD dihydroxy-acid dehydratase low > 57
Escherichia coli BL21 1.00 ECD_00108 quinolinate phosphoribosyltransferase 1.00 ECD_03649 dihydroxyacid dehydratase low > 60
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03552 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 1.00 OHPLBJKB_04282 Dihydroxy-acid dehydratase low > 73
Escherichia coli ECRC102 1.00 NIAGMN_08380 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 NIAGMN_12395 ilvD dihydroxy-acid dehydratase — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS00585 carboxylating nicotinate-nucleotide diphosphorylase 0.99 ECOLIN_RS21665 dihydroxy-acid dehydratase low > 52
Escherichia fergusonii Becca 1.00 EFB2_03940 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.99 EFB2_04865 Dihydroxy-acid dehydratase low > 86
Escherichia coli ECRC101 1.00 MCAODC_01045 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 MCAODC_05145 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC62 1.00 BNILDI_08735 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 BNILDI_04750 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC98 1.00 JDDGAC_14125 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 JDDGAC_18260 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC99 1.00 KEDOAH_17625 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 KEDOAH_13510 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECRC101 1.00 OKFHMN_10530 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 OKFHMN_14640 ilvD dihydroxy-acid dehydratase — —
Escherichia coli ECOR38 0.99 HEPCGN_08510 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 HEPCGN_13350 ilvD dihydroxy-acid dehydratase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.87 GFF130 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.97 GFF2901 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 78
Klebsiella michiganensis M5al 0.81 BWI76_RS04845 nicotinate-nucleotide pyrophosphorylase 0.96 BWI76_RS00975 dihydroxy-acid dehydratase 0.45 25
Enterobacter sp. TBS_079 0.81 MPMX20_00800 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.97 MPMX20_04499 Dihydroxy-acid dehydratase 0.35 44
Enterobacter asburiae PDN3 0.81 EX28DRAFT_3702 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.96 EX28DRAFT_4443 dihydroxy-acid dehydratase low > 76
Rahnella sp. WP5 0.74 EX31_RS03515 carboxylating nicotinate-nucleotide diphosphorylase 0.87 EX31_RS15005 dihydroxy-acid dehydratase 0.55 46
Serratia liquefaciens MT49 0.71 IAI46_03530 carboxylating nicotinate-nucleotide diphosphorylase 0.90 IAI46_24345 dihydroxy-acid dehydratase low > 86
Erwinia tracheiphila SCR3 0.70 LU632_RS03040 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.86 LU632_RS24400 ilvD dihydroxy-acid dehydratase low > 74
Pectobacterium carotovorum WPP14 0.69 HER17_RS03250 carboxylating nicotinate-nucleotide diphosphorylase 0.91 HER17_RS01075 dihydroxy-acid dehydratase 0.88 23
Pantoea sp. MT58 0.69 IAI47_15845 carboxylating nicotinate-nucleotide diphosphorylase 0.89 IAI47_01035 dihydroxy-acid dehydratase 0.48 65
Dickeya dadantii 3937 0.67 DDA3937_RS17955 carboxylating nicotinate-nucleotide diphosphorylase 0.92 DDA3937_RS20155 dihydroxy-acid dehydratase low > 74
Dickeya dianthicola ME23 0.66 DZA65_RS19035 carboxylating nicotinate-nucleotide diphosphorylase 0.91 DZA65_RS21335 dihydroxy-acid dehydratase 0.72 46
Dickeya dianthicola 67-19 0.66 HGI48_RS17890 carboxylating nicotinate-nucleotide diphosphorylase 0.91 HGI48_RS20295 dihydroxy-acid dehydratase 0.55 52
Shewanella amazonensis SB2B 0.58 Sama_0371 nicotinate-nucleotide diphosphorylase (carboxylating) (RefSeq) 0.79 Sama_3279 dihydroxy-acid dehydratase (RefSeq) — —
Vibrio cholerae E7946 ATCC 55056 0.58 CSW01_12265 carboxylating nicotinate-nucleotide diphosphorylase 0.85 CSW01_00140 dihydroxy-acid dehydratase low > 62
Shewanella sp. ANA-3 0.55 Shewana3_0422 nicotinate-nucleotide pyrophosphorylase [carboxylating] (RefSeq) 0.80 Shewana3_0358 dihydroxy-acid dehydratase (RefSeq) — —
Shewanella loihica PV-4 0.54 Shew_3435 nicotinate-nucleotide pyrophosphorylase (RefSeq) 0.78 Shew_0292 dihydroxy-acid dehydratase (RefSeq) — —
Alteromonas macleodii MIT1002 0.52 MIT1002_03008 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.79 MIT1002_04041 Dihydroxy-acid dehydratase — —
Pseudomonas stutzeri RCH2 0.52 Psest_0718 nicotinate-nucleotide pyrophosphorylase 0.75 Psest_0234 dihydroxy-acid dehydratase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.51 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.74 Psyr_0469 dihydroxyacid dehydratase low > 86
Pseudomonas syringae pv. syringae B728a 0.51 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.74 Psyr_0469 dihydroxyacid dehydratase 0.66 24
Pseudomonas fluorescens FW300-N2E3 0.50 AO353_05520 nicotinate-nucleotide pyrophosphorylase 0.75 AO353_08345 dihydroxy-acid dehydratase 0.35 67
Pseudomonas sp. RS175 0.50 PFR28_00098 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.75 PFR28_04278 Dihydroxy-acid dehydratase low > 88
Pseudomonas putida KT2440 0.49 PP_0787 quinolinate phosphoribosyltransferase (decarboxylating) monomer 0.74 PP_5128 Dihydroxy-acid dehydratase 0.63 27
Pseudomonas fluorescens SBW25 0.49 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase 0.75 PFLU_RS28535 dihydroxy-acid dehydratase low > 109
Pseudomonas fluorescens SBW25-INTG 0.49 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase 0.75 PFLU_RS28535 dihydroxy-acid dehydratase 0.46 29
Acinetobacter radioresistens SK82 0.49 MPMX26_00042 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.29 MPMX26_03019 Dihydroxy-acid dehydratase low > 36
Pseudomonas fluorescens FW300-N1B4 0.48 Pf1N1B4_1153 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.75 Pf1N1B4_2303 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 87
Pseudomonas simiae WCS417 0.48 PS417_03925 nicotinate-nucleotide pyrophosphorylase 0.75 PS417_26890 dihydroxy-acid dehydratase 0.44 35
Marinobacter adhaerens HP15 0.48 HP15_1305 nicotinate-nucleotide pyrophosphorylase 0.70 HP15_595 dihydroxy-acid dehydratase — —
Pseudomonas fluorescens FW300-N2E2 0.48 Pf6N2E2_3346 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.75 Pf6N2E2_4564 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.49 9
Pseudomonas fluorescens FW300-N2C3 0.48 AO356_07370 nicotinate-nucleotide pyrophosphorylase 0.75 AO356_13250 dihydroxy-acid dehydratase 0.40 52
Pseudomonas sp. S08-1 0.48 OH686_16520 nicotinate-nucleotide diphosphorylase (carboxylating) 0.75 OH686_14100 dihydroxy-acid dehydratase low > 80
Pseudomonas fluorescens GW456-L13 0.47 PfGW456L13_5082 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.75 PfGW456L13_973 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.71 6
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS13795 carboxylating nicotinate-nucleotide diphosphorylase 0.26 LRK54_RS10320 dihydroxy-acid dehydratase low > 59
Rhodanobacter denitrificans MT42 0.45 LRK55_RS13510 carboxylating nicotinate-nucleotide diphosphorylase 0.26 LRK55_RS09960 dihydroxy-acid dehydratase low > 63
Dyella japonica UNC79MFTsu3.2 0.45 ABZR86_RS09850 carboxylating nicotinate-nucleotide diphosphorylase 0.28 ABZR86_RS15945 dihydroxy-acid dehydratase low > 74
Dechlorosoma suillum PS 0.44 Dsui_2901 nicotinate-nucleotide pyrophosphorylase 0.74 Dsui_1122 dihydroxy-acid dehydratase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.42 GFF1217 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.64 GFF2073 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 90
Ralstonia solanacearum PSI07 0.42 RPSI07_RS12655 nicotinate-nucleotide diphosphorylase (carboxylating) 0.29 RPSI07_RS12840 dihydroxy-acid dehydratase — —
Ralstonia sp. UNC404CL21Col 0.41 ABZR87_RS00350 carboxylating nicotinate-nucleotide diphosphorylase 0.75 ABZR87_RS00240 dihydroxy-acid dehydratase low > 80
Ralstonia solanacearum UW163 0.41 UW163_RS08940 nicotinate-nucleotide diphosphorylase (carboxylating) 0.29 UW163_RS09135 dihydroxy-acid dehydratase — —
Ralstonia solanacearum IBSBF1503 0.41 RALBFv3_RS04730 nicotinate-nucleotide diphosphorylase (carboxylating) 0.29 RALBFv3_RS04535 dihydroxy-acid dehydratase — —
Acidovorax sp. GW101-3H11 0.40 Ac3H11_3838 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.74 Ac3H11_955 Dihydroxy-acid dehydratase (EC 4.2.1.9) 0.65 53
Herbaspirillum seropedicae SmR1 0.40 HSERO_RS11070 nicotinate-nucleotide pyrophosphorylase 0.74 HSERO_RS02650 dihydroxy-acid dehydratase 0.81 10
Cupriavidus basilensis FW507-4G11 0.40 RR42_RS17015 nicotinate-nucleotide pyrophosphorylase 0.29 RR42_RS16210 dihydroxy-acid dehydratase — —
Castellaniella sp019104865 MT123 0.39 ABCV34_RS03695 carboxylating nicotinate-nucleotide diphosphorylase 0.72 ABCV34_RS14810 dihydroxy-acid dehydratase low > 48
Paraburkholderia graminis OAS925 0.39 ABIE53_003293 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.74 ABIE53_006513 dihydroxy-acid dehydratase low > 113
Ralstonia solanacearum GMI1000 0.39 RS_RS12290 nicotinate-nucleotide diphosphorylase (carboxylating) 0.28 RS_RS12105 dihydroxy-acid dehydratase — —
Variovorax sp. OAS795 0.39 ABID97_RS07410 carboxylating nicotinate-nucleotide diphosphorylase 0.31 ABID97_RS17500 dihydroxy-acid dehydratase — —
Burkholderia phytofirmans PsJN 0.38 BPHYT_RS15645 nicotinate-nucleotide pyrophosphorylase 0.74 BPHYT_RS10100 dihydroxy-acid dehydratase 0.39 42
Paraburkholderia sabiae LMG 24235 0.38 QEN71_RS03065 carboxylating nicotinate-nucleotide diphosphorylase 0.74 QEN71_RS21095 dihydroxy-acid dehydratase low > 153
Paraburkholderia bryophila 376MFSha3.1 0.38 H281DRAFT_04070 nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.74 H281DRAFT_05312 dihydroxyacid dehydratase low > 103
Lysobacter sp. OAE881 0.37 ABIE51_RS15405 carboxylating nicotinate-nucleotide diphosphorylase 0.27 ABIE51_RS17540 dihydroxy-acid dehydratase low > 62
Variovorax sp. SCN45 0.36 GFF2574 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.31 GFF471 Dihydroxy-acid dehydratase (EC 4.2.1.9) — —
Rhodopseudomonas palustris CGA009 0.35 TX73_005415 carboxylating nicotinate-nucleotide diphosphorylase 0.74 TX73_007515 dihydroxy-acid dehydratase — —
Xanthomonas campestris pv. campestris strain 8004 0.35 Xcc-8004.2009.1 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.72 Xcc-8004.451.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) low > 74
Bosea sp. OAE506 0.35 ABIE41_RS02500 carboxylating nicotinate-nucleotide diphosphorylase 0.29 ABIE41_RS15690 dihydroxy-acid dehydratase — —
Magnetospirillum magneticum AMB-1 0.34 AMB_RS19655 nicotinate-nucleotide diphosphorylase (carboxylating) 0.73 AMB_RS12770 dihydroxy-acid dehydratase — —
Rhizobium sp. OAE497 0.33 ABIE40_RS23265 carboxylating nicotinate-nucleotide diphosphorylase 0.75 ABIE40_RS08005 dihydroxy-acid dehydratase 0.54 80
Rhodospirillum rubrum S1H 0.33 Rru_A1432 Nicotinate-nucleotide pyrophosphorylase (NCBI) 0.71 Rru_A1786 Dihydroxy-acid dehydratase (NCBI) 0.85 10
Caulobacter crescentus NA1000 0.33 CCNA_03009 nicotinate-nucleotide pyrophosphorylase 0.72 CCNA_03139 dihydroxy-acid dehydratase — —
Caulobacter crescentus NA1000 Δfur 0.33 CCNA_03009 nicotinate-nucleotide pyrophosphorylase 0.72 CCNA_03139 dihydroxy-acid dehydratase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.33 A4249_RS00635 carboxylating nicotinate-nucleotide diphosphorylase 0.25 A4249_RS10030 dihydroxy-acid dehydratase low > 48
Mycobacterium tuberculosis H37Rv 0.32 Rv1596 Probable nicotinate-nucleotide pyrophosphatase NadC 0.31 Rv0189c Probable dihydroxy-acid dehydratase IlvD (dad) — —
Parabacteroides merdae CL09T00C40 0.32 HMPREF1078_RS16725 carboxylating nicotinate-nucleotide diphosphorylase 0.65 HMPREF1078_RS16695 dihydroxy-acid dehydratase — —
Agrobacterium fabrum C58 0.32 Atu4096 nicotinate-nucleotide pyrophosphorylase 0.73 Atu1918 dihydroxy-acid dehydratase — —
Azospirillum sp. SherDot2 0.31 MPMX19_05672 putative nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.74 MPMX19_05356 Dihydroxy-acid dehydratase — —
Pedobacter sp. GW460-11-11-14-LB5 0.31 CA265_RS14530 nicotinate-nucleotide diphosphorylase (carboxylating) 0.27 CA265_RS15795 dihydroxy-acid dehydratase low > 88
Mucilaginibacter yixingensis YX-36 DSM 26809 0.31 ABZR88_RS15695 carboxylating nicotinate-nucleotide diphosphorylase 0.27 ABZR88_RS11575 dihydroxy-acid dehydratase — —
Bacteroides ovatus ATCC 8483 0.31 BACOVA_04303 nicotinate-nucleotide diphosphorylase (carboxylating) 0.62 BACOVA_03302 dihydroxy-acid dehydratase 0.86 19
Pontibacter actiniarum KMM 6156, DSM 19842 0.31 CA264_16940 nicotinate-nucleotide diphosphorylase (carboxylating) 0.28 CA264_06935 dihydroxy-acid dehydratase — —
Bacteroides stercoris CC31F 0.30 HMPREF1181_RS10745 carboxylating nicotinate-nucleotide diphosphorylase 0.64 HMPREF1181_RS08335 dihydroxy-acid dehydratase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.30 Echvi_1158 nicotinate-nucleotide pyrophosphorylase 0.29 Echvi_2055 dihydroxy-acid dehydratase low > 79
Bacteroides thetaiotaomicron VPI-5482 0.30 BT1560 nicotinate-nucleotide pyrophosphorylase (NCBI ptt file) 0.63 BT2078 dihydroxy-acid dehydratase (NCBI ptt file) — —
Bifidobacterium breve UCC2003 0.30 BBR_RS16720 nicotinate-nucleotide diphosphorylase (carboxylating) 0.56 BBR_RS17635 dihydroxy-acid dehydratase low > 34
Phocaeicola vulgatus CL09T03C04 0.30 HMPREF1058_RS15940 carboxylating nicotinate-nucleotide diphosphorylase 0.64 HMPREF1058_RS16815 dihydroxy-acid dehydratase — —
Phocaeicola dorei CL03T12C01 0.30 ABI39_RS11900 carboxylating nicotinate-nucleotide diphosphorylase 0.64 ABI39_RS12715 dihydroxy-acid dehydratase — —
Sphingomonas koreensis DSMZ 15582 0.29 Ga0059261_0061 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.28 Ga0059261_4216 Dihydroxyacid dehydratase/phosphogluconate dehydratase — —
Phaeobacter inhibens DSM 17395 0.28 PGA1_c27810 nicotinate-nucleotide pyrophosphorylase 0.70 PGA1_c29490 dihydroxy-acid dehydratase LivD low > 62
Synechococcus elongatus PCC 7942 0.27 Synpcc7942_0951 nadC nicotinate-nucleotide pyrophosphorylase 0.75 Synpcc7942_0626 ilvD dihydroxy-acid dehydratase — —
Sinorhizobium meliloti 1021 0.25 SMc02598 nicotinate-nucleotide pyrophosphorylase carboxylating protein 0.75 SMc04045 dihydroxy-acid dehydratase low > 103
Methanococcus maripaludis JJ 0.24 MMJJ_RS00575 carboxylating nicotinate-nucleotide diphosphorylase 0.35 MMJJ_RS03675 dihydroxy-acid dehydratase — —
Methanococcus maripaludis S2 0.24 MMP_RS04560 carboxylating nicotinate-nucleotide diphosphorylase 0.35 MMP_RS01700 dihydroxy-acid dehydratase — —

Not shown: 2 genomes with orthologs for b0109 only; 6 genomes with orthologs for b3771 only