Conservation of cofitness between b2518 and b0888 in Escherichia coli BW25113

96 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2518 ndk nucleoside diphosphate kinase (NCBI) 1.0 b0888 trxB thioredoxin reductase, FAD/NAD(P)-binding (NCBI) 0.35 11
Escherichia coli BL21 1.00 ECD_02410 multifunctional nucleoside diphosphate kinase and apyrimidinic endonuclease and 3'-phosphodiesterase 1.00 ECD_00892 thioredoxin reductase, FAD/NAD(P)-binding — —
Escherichia coli ECRC98 1.00 JDDGAC_25380 ndk nucleoside-diphosphate kinase 1.00 JDDGAC_09390 trxB thioredoxin-disulfide reductase — —
Escherichia coli ECOR27 1.00 NOLOHH_13355 ndk nucleoside-diphosphate kinase 1.00 NOLOHH_22150 trxB thioredoxin-disulfide reductase — —
Escherichia coli ECRC101 1.00 MCAODC_12235 ndk nucleoside-diphosphate kinase 1.00 MCAODC_24970 trxB thioredoxin-disulfide reductase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01191 Nucleoside diphosphate kinase 1.00 OHPLBJKB_02780 Thioredoxin reductase low > 73
Escherichia coli ECRC102 1.00 NIAGMN_19475 ndk nucleoside-diphosphate kinase 1.00 NIAGMN_03300 trxB thioredoxin-disulfide reductase — —
Escherichia coli ECRC101 1.00 OKFHMN_21705 ndk nucleoside-diphosphate kinase 1.00 OKFHMN_05580 trxB thioredoxin-disulfide reductase — —
Escherichia coli ECRC62 1.00 BNILDI_12155 ndk nucleoside-diphosphate kinase 1.00 BNILDI_20405 trxB thioredoxin-disulfide reductase — —
Escherichia coli ECRC99 1.00 KEDOAH_06515 ndk nucleoside-diphosphate kinase 1.00 KEDOAH_22155 trxB thioredoxin-disulfide reductase — —
Escherichia coli Nissle 1917 0.99 ECOLIN_RS14305 nucleoside-diphosphate kinase 0.99 ECOLIN_RS04725 thioredoxin-disulfide reductase — —
Escherichia fergusonii Becca 0.99 EFB2_01372 Nucleoside diphosphate kinase 0.99 EFB2_03173 Thioredoxin reductase low > 86
Escherichia coli ECOR38 0.99 HEPCGN_20825 ndk nucleoside-diphosphate kinase 0.99 HEPCGN_22930 trxB thioredoxin-disulfide reductase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF2415 Nucleoside diphosphate kinase (EC 2.7.4.6) 0.97 GFF4892 Thioredoxin reductase (EC 1.8.1.9) low > 78
Klebsiella michiganensis M5al 0.96 BWI76_RS21100 nucleoside-diphosphate kinase 0.96 BWI76_RS09645 thioredoxin-disulfide reductase low > 92
Enterobacter asburiae PDN3 0.95 EX28DRAFT_0125 nucleoside diphosphate kinase (EC 2.7.4.6) 0.94 EX28DRAFT_2044 thioredoxin-disulfide reductase — —
Enterobacter sp. TBS_079 0.95 MPMX20_03396 Nucleoside diphosphate kinase 0.96 MPMX20_01550 Thioredoxin reductase low > 85
Erwinia tracheiphila SCR3 0.91 LU632_RS17820 ndk nucleoside-diphosphate kinase 0.86 LU632_RS09730 trxB thioredoxin-disulfide reductase low > 74
Pantoea sp. MT58 0.90 IAI47_05035 nucleoside-diphosphate kinase 0.89 IAI47_12920 thioredoxin-disulfide reductase low > 76
Dickeya dadantii 3937 0.81 DDA3937_RS15485 nucleoside-diphosphate kinase 0.86 DDA3937_RS09585 thioredoxin-disulfide reductase 0.59 8
Dickeya dianthicola 67-19 0.81 HGI48_RS15595 nucleoside-diphosphate kinase 0.86 HGI48_RS09600 thioredoxin-disulfide reductase — —
Serratia liquefaciens MT49 0.81 IAI46_19295 nucleoside-diphosphate kinase 0.87 IAI46_08550 thioredoxin-disulfide reductase low > 86
Dickeya dianthicola ME23 0.80 DZA65_RS16670 nucleoside-diphosphate kinase 0.86 DZA65_RS09910 thioredoxin-disulfide reductase low > 75
Pectobacterium carotovorum WPP14 0.80 HER17_RS06080 nucleoside-diphosphate kinase 0.89 HER17_RS12365 thioredoxin-disulfide reductase 0.43 57
Rahnella sp. WP5 0.79 EX31_RS20530 nucleoside-diphosphate kinase 0.86 EX31_RS18535 thioredoxin-disulfide reductase low > 89
Alteromonas macleodii MIT1002 0.74 MIT1002_02793 Nucleoside diphosphate kinase 0.79 MIT1002_01838 Thioredoxin reductase — —
Kangiella aquimarina DSM 16071 0.73 B158DRAFT_1148 nucleoside diphosphate kinase (EC 2.7.4.6) 0.74 B158DRAFT_1829 thioredoxin-disulfide reductase — —
Shewanella sp. ANA-3 0.73 Shewana3_2272 nucleoside diphosphate kinase (RefSeq) 0.81 Shewana3_2047 thioredoxin reductase (RefSeq) — —
Shewanella loihica PV-4 0.72 Shew_2310 nucleoside-diphosphate kinase (RefSeq) 0.81 Shew_2028 thioredoxin reductase (RefSeq) — —
Acinetobacter radioresistens SK82 0.71 MPMX26_00425 Nucleoside diphosphate kinase 0.71 MPMX26_02425 Thioredoxin reductase — —
Shewanella oneidensis MR-1 0.71 SO2274 ndk nucleoside diphosphate kinase (NCBI ptt file) 0.81 SO2303 trxB thioredoxin reductase (NCBI ptt file) — —
Shewanella amazonensis SB2B 0.71 Sama_1301 ndk nucleoside diphosphate kinase (RefSeq) 0.82 Sama_1769 thioredoxin reductase (RefSeq) — —
Marinobacter adhaerens HP15 0.70 HP15_1489 nucleoside diphosphate kinase 0.72 HP15_2076 secreted protein containing thioredoxin reductase domain — —
Vibrio cholerae E7946 ATCC 55056 0.69 CSW01_03925 nucleoside-diphosphate kinase 0.83 CSW01_05985 thioredoxin-disulfide reductase — —
Pseudomonas sp. S08-1 0.66 OH686_17510 Nucleoside diphosphate kinase 0.73 OH686_00255 thioredoxin-disulfide reductase — —
Pseudomonas stutzeri RCH2 0.65 Psest_1258 Nucleoside diphosphate kinase 0.73 Psest_2031 thioredoxin-disulfide reductase — —
Xanthomonas campestris pv. campestris strain 8004 0.65 Xcc-8004.2738.1 Nucleoside diphosphate kinase (EC 2.7.4.6) 0.68 Xcc-8004.2750.1 Thioredoxin reductase (EC 1.8.1.9) — —
Rhodanobacter denitrificans FW104-10B01 0.64 LRK54_RS00065 nucleoside-diphosphate kinase 0.68 LRK54_RS17260 thioredoxin-disulfide reductase — —
Rhodanobacter denitrificans MT42 0.64 LRK55_RS18060 nucleoside-diphosphate kinase 0.68 LRK55_RS17485 thioredoxin-disulfide reductase — —
Dyella japonica UNC79MFTsu3.2 0.64 ABZR86_RS05460 nucleoside-diphosphate kinase 0.65 ABZR86_RS01805 thioredoxin-disulfide reductase — —
Pseudomonas putida KT2440 0.64 PP_0849 Nucleoside diphosphate kinase 0.73 PP_0786 thioredoxin reductase — —
Rhodanobacter sp. FW510-T8 0.64 OKGIIK_07145 ndk nucleoside-diphosphate kinase 0.68 OKGIIK_07630 trxB thioredoxin-disulfide reductase — —
Paraburkholderia graminis OAS925 0.64 ABIE53_002745 nucleoside-diphosphate kinase 0.69 ABIE53_001285 thioredoxin reductase (NADPH) — —
Pseudomonas fluorescens FW300-N2E2 0.63 Pf6N2E2_3182 Nucleoside diphosphate kinase (EC 2.7.4.6) 0.72 Pf6N2E2_5268 Thioredoxin reductase (EC 1.8.1.9) — —
Pseudomonas fluorescens FW300-N2C3 0.63 AO356_06610 nucleoside diphosphate kinase 0.72 AO356_16715 thioredoxin reductase — —
Cupriavidus basilensis FW507-4G11 0.63 RR42_RS13160 nucleoside diphosphate kinase 0.70 RR42_RS04315 thioredoxin reductase — —
Paraburkholderia bryophila 376MFSha3.1 0.63 H281DRAFT_00513 nucleoside diphosphate kinase 0.69 H281DRAFT_00173 thioredoxin reductase (NADPH) — —
Lysobacter sp. OAE881 0.63 ABIE51_RS09410 nucleoside-diphosphate kinase 0.68 ABIE51_RS11465 thioredoxin-disulfide reductase — —
Burkholderia phytofirmans PsJN 0.63 BPHYT_RS12595 nucleoside diphosphate kinase 0.68 BPHYT_RS05070 thioredoxin reductase — —
Pseudomonas sp. RS175 0.63 PFR28_00293 Nucleoside diphosphate kinase 0.72 PFR28_00202 Glucosaminate ammonia-lyase — —
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_15870 nucleoside diphosphate kinase 0.72 AO353_05015 thioredoxin reductase — —
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_4866 Nucleoside diphosphate kinase (EC 2.7.4.6) 0.71 PfGW456L13_4983 Thioredoxin reductase (EC 1.8.1.9) — —
Pseudomonas fluorescens FW300-N1B4 0.62 Pf1N1B4_858 Nucleoside diphosphate kinase (EC 2.7.4.6) 0.71 Pf1N1B4_1046 Thioredoxin reductase (EC 1.8.1.9) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.62 Psyr_1244 nucleoside diphosphate kinase 0.73 Psyr_1016 Thioredoxin reductase — —
Pseudomonas syringae pv. syringae B728a 0.62 Psyr_1244 nucleoside diphosphate kinase 0.73 Psyr_1016 Thioredoxin reductase — —
Pseudomonas fluorescens SBW25 0.61 PFLU_RS24820 nucleoside-diphosphate kinase 0.73 PFLU_RS25330 thioredoxin-disulfide reductase — —
Pseudomonas simiae WCS417 0.61 PS417_23165 nucleoside diphosphate kinase 0.73 PS417_23515 thioredoxin reductase — —
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS24820 nucleoside-diphosphate kinase 0.73 PFLU_RS25330 thioredoxin-disulfide reductase — —
Variovorax sp. OAS795 0.61 ABID97_RS14205 nucleoside-diphosphate kinase 0.68 ABID97_RS07815 thioredoxin-disulfide reductase — —
Variovorax sp. SCN45 0.61 GFF991 Nucleoside diphosphate kinase (EC 2.7.4.6) 0.68 GFF6038 Thioredoxin reductase (EC 1.8.1.9) — —
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS05960 nucleoside-diphosphate kinase 0.68 QEN71_RS03380 thioredoxin-disulfide reductase — —
Rhodospirillum rubrum S1H 0.60 Rru_A2169 Nucleoside-diphosphate kinase (NCBI) 0.50 Rru_A2898 Thioredoxin reductase (NCBI) — —
Dechlorosoma suillum PS 0.59 Dsui_3146 nucleoside diphosphate kinase 0.72 Dsui_1689 thioredoxin-disulfide reductase — —
Castellaniella sp019104865 MT123 0.58 ABCV34_RS02605 nucleoside-diphosphate kinase 0.68 ABCV34_RS07235 thioredoxin-disulfide reductase — —
Herbaspirillum seropedicae SmR1 0.58 HSERO_RS14815 nucleoside diphosphate kinase 0.71 HSERO_RS09495 thioredoxin reductase — —
Ralstonia solanacearum PSI07 0.57 RPSI07_RS18120 nucleoside-diphosphate kinase 0.68 RPSI07_RS13185 thioredoxin-disulfide reductase — —
Phaeobacter inhibens DSM 17395 0.57 PGA1_c19750 nucleoside diphosphate kinase Ndk 0.55 PGA1_c24780 thioredoxin reductase TrxB — —
Sphingomonas koreensis DSMZ 15582 0.57 Ga0059261_0873 nucleoside diphosphate kinase (EC 2.7.4.6) 0.52 Ga0059261_4182 thioredoxin-disulfide reductase — —
Ralstonia sp. UNC404CL21Col 0.57 ABZR87_RS10895 nucleoside-diphosphate kinase 0.68 ABZR87_RS16065 thioredoxin-disulfide reductase — —
Ralstonia solanacearum UW163 0.56 UW163_RS12720 nucleoside-diphosphate kinase 0.68 UW163_RS09505 thioredoxin-disulfide reductase — —
Ralstonia solanacearum IBSBF1503 0.56 RALBFv3_RS15255 nucleoside-diphosphate kinase 0.68 RALBFv3_RS04165 thioredoxin-disulfide reductase — —
Ralstonia solanacearum GMI1000 0.56 RS_RS06065 nucleoside-diphosphate kinase 0.68 RS_RS11755 thioredoxin-disulfide reductase — —
Magnetospirillum magneticum AMB-1 0.56 AMB_RS18020 nucleoside-diphosphate kinase 0.52 AMB_RS03410 thioredoxin-disulfide reductase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.56 GFF4867 Nucleoside diphosphate kinase (EC 2.7.4.6) 0.70 GFF773 Thioredoxin reductase (EC 1.8.1.9) — —
Acidovorax sp. GW101-3H11 0.56 Ac3H11_1790 Nucleoside diphosphate kinase (EC 2.7.4.6) 0.70 Ac3H11_1700 Thioredoxin reductase (EC 1.8.1.9) — —
Dinoroseobacter shibae DFL-12 0.55 Dshi_1350 Nucleoside-diphosphate kinase (RefSeq) 0.54 Dshi_2654 thioredoxin reductase (RefSeq) — —
Azospirillum brasilense Sp245 0.54 AZOBR_RS16305 nucleoside diphosphate kinase 0.53 AZOBR_RS12935 thioredoxin reductase — —
Agrobacterium fabrum C58 0.54 Atu1122 nucleoside diphosphate kinase 0.51 Atu2185 thioredoxin reductase — —
Sinorhizobium meliloti 1021 0.54 SMc00595 nucleoside diphosphate kinase 0.51 SMc01224 thioredoxin reductase — —
Azospirillum sp. SherDot2 0.54 MPMX19_01455 Nucleoside diphosphate kinase 0.53 MPMX19_00232 Thioredoxin reductase — —
Rhodopseudomonas palustris CGA009 0.52 TX73_015810 nucleoside-diphosphate kinase 0.48 TX73_021110 thioredoxin-disulfide reductase — —
Rhizobium sp. OAE497 0.52 ABIE40_RS06465 nucleoside-diphosphate kinase 0.52 ABIE40_RS12865 thioredoxin-disulfide reductase — —
Bosea sp. OAE506 0.51 ABIE41_RS17075 nucleoside-diphosphate kinase 0.53 ABIE41_RS11885 thioredoxin-disulfide reductase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.48 A4249_RS08235 nucleoside-diphosphate kinase 0.47 A4249_RS00680 thioredoxin-disulfide reductase — —
Caulobacter crescentus NA1000 0.48 CCNA_01770 nucleoside diphosphate kinase 0.49 CCNA_02964 thioredoxin-disulfide reductase — —
Caulobacter crescentus NA1000 Δfur 0.48 CCNA_01770 nucleoside diphosphate kinase 0.49 CCNA_02964 thioredoxin-disulfide reductase — —
Pedobacter sp. GW460-11-11-14-LB5 0.45 CA265_RS24780 nucleoside-diphosphate kinase 0.49 CA265_RS10630 thioredoxin-disulfide reductase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.45 Echvi_0995 Nucleoside diphosphate kinase 0.46 Echvi_3438 thioredoxin-disulfide reductase — —
Methanococcus maripaludis S2 0.45 MMP_RS01525 nucleoside-diphosphate kinase 0.22 MMP_RS04970 F420-dependent thioredoxin reductase low > 25
Pontibacter actiniarum KMM 6156, DSM 19842 0.44 CA264_18820 nucleoside-diphosphate kinase 0.43 CA264_04890 thioredoxin-disulfide reductase — —
Methanococcus maripaludis JJ 0.43 MMJJ_RS03850 nucleoside-diphosphate kinase 0.22 MMJJ_RS00165 F420-dependent thioredoxin reductase low > 28
Mycobacterium tuberculosis H37Rv 0.42 Rv2445c Probable nucleoside diphosphate kinase NdkA (NDK) (NDP kinase) (nucleoside-2-P kinase) 0.44 Rv3913 Probable thioredoxin reductase TrxB2 (TRXR) (TR) — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.41 ABZR88_RS21635 nucleoside-diphosphate kinase 0.48 ABZR88_RS10305 thioredoxin-disulfide reductase — —
Phocaeicola vulgatus CL09T03C04 0.36 HMPREF1058_RS08290 nucleoside-diphosphate kinase 0.43 HMPREF1058_RS05865 thioredoxin-disulfide reductase — —
Phocaeicola dorei CL03T12C01 0.36 ABI39_RS02465 nucleoside-diphosphate kinase 0.43 ABI39_RS18240 thioredoxin-disulfide reductase — —
Bacteroides thetaiotaomicron VPI-5482 0.36 BT3925 nucleoside diphosphate kinase (NCBI ptt file) 0.43 BT4336 thioredoxin reductase (NCBI ptt file) — —
Bacteroides ovatus ATCC 8483 0.36 BACOVA_01151 nucleoside diphosphate kinase 0.44 BACOVA_05140 thioredoxin-disulfide reductase — —

Not shown: 3 genomes with orthologs for b2518 only; 3 genomes with orthologs for b0888 only