Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Paraburkholderia sabiae LMG 24235 | QEN71_RS11000 | | HD domain-containing protein | insig. | 100 | 100 |
o | Azospirillum brasilense Sp245 | AZOBR_RS11055 | | phosphohydrolase | insig. | 58 | 93 |
o | Azospirillum sp. SherDot2 | MPMX19_00914 | | hypothetical protein | insig. | 56 | 93 |
o | Rhodopseudomonas palustris CGA009 | TX73_018975 | | HD domain-containing protein | insig. | 49 | 94 |
| Phaeobacter inhibens DSM 17395 | PGA1_c01010 | | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase SpoT | strong | 36 | 95 |
| Dinoroseobacter shibae DFL-12 | Dshi_0194 | | (p)ppGpp synthetase I, SpoT/RelA (RefSeq) | strong | 35 | 79 |
| Shewanella sp. ANA-3 | Shewana3_3812 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | strong | 35 | 98 |
| Mycobacterium tuberculosis H37Rv | Rv2583c | | Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase) | strong | 38 | 75 |
| Azospirillum sp. SherDot2 | MPMX19_03695 | | hypothetical protein | insig. | 34 | 96 |
| Lysobacter sp. OAE881 | ABIE51_RS17265 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | no data | 34 | 97 |
| Rhodopseudomonas palustris CGA009 | TX73_013955 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 37 | 75 |
| Shewanella oneidensis MR-1 | SO0359 | spoT | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (NCBI ptt file) | strong | 34 | 98 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1215.1 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | no data | 38 | 73 |
| Shewanella loihica PV-4 | Shew_3499 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | strong | 34 | 98 |
| Shewanella amazonensis SB2B | Sama_0264 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | strong | 34 | 98 |
| Desulfovibrio vulgaris Hildenborough JW710 | DVU2083 | relA | GTP pyrophosphokinase (TIGR) | sig. | 38 | 72 |
| Rhodanobacter denitrificans FW104-10B01 | LRK54_RS11795 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | no data | 36 | 78 |
o | Magnetospirillum magneticum AMB-1 | AMB_RS15965 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | insig. | 33 | 96 |
| Rhodanobacter denitrificans MT42 | LRK55_RS11520 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | no data | 36 | 78 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS11850 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | no data | 37 | 71 |
| Pantoea sp. MT58 | IAI47_18680 | | HD domain-containing protein | insig. | 40 | 72 |
| Erwinia tracheiphila SCR3 | LU632_RS00230 | | HD domain-containing protein | insig. | 42 | 63 |
| Rhodanobacter sp. FW510-T8 | OKGIIK_12100 | spoT | guanosine-3',5'-bis(diphosphate) 3'-diphosphatase | no data | 36 | 71 |
| Castellaniella sp019104865 MT123 | ABCV34_RS03095 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | no data | 36 | 95 |
| Pseudomonas stutzeri RCH2 | Psest_3817 | | (p)ppGpp synthetase, RelA/SpoT family | no data | 36 | 72 |
| Agrobacterium fabrum C58 | Atu1030 | | GTP pyrophosphohydrolase/synthetase, RelA/SpoT family | insig. | 36 | 73 |
| Pseudomonas fluorescens SBW25 | PFLU_RS29510 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | no data | 35 | 72 |
| Pseudomonas fluorescens SBW25-INTG | PFLU_RS29510 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | no data | 35 | 72 |
| Pseudomonas simiae WCS417 | PS417_27830 | | (p)ppGpp synthetase | no data | 35 | 72 |
| Pseudomonas syringae pv. syringae B728a | Psyr_0209 | | RelA/SpoT protein | no data | 35 | 72 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_0209 | | RelA/SpoT protein | no data | 35 | 72 |
| Pseudomonas fluorescens FW300-N2E3 | AO353_09280 | | (p)ppGpp synthetase | no data | 35 | 72 |
| Pseudomonas sp. S08-1 | OH686_13550 | | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase / GTP pyrophosphokinase , (p)ppGpp synthetase II | insig. | 34 | 72 |
| Pseudomonas sp. RS175 | PFR28_04424 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | no data | 35 | 72 |
| Pseudomonas fluorescens GW456-L13 | PfGW456L13_780 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | no data | 35 | 72 |
| Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2113 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | no data | 35 | 72 |
| Pseudomonas fluorescens FW300-N2C3 | AO356_12480 | | (p)ppGpp synthetase | no data | 35 | 72 |
| Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_4361 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | no data | 35 | 72 |
o | Ralstonia solanacearum PSI07 | RPSI07_RS07975 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | insig. | 34 | 98 |
| Pseudomonas putida KT2440 | PP_5302 | | bifunctional (p)ppGpp synthase/hydrolase | no data | 34 | 72 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1034 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | no data | 37 | 74 |
| Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS05505 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | cofit | 35 | 74 |
o | Cupriavidus basilensis FW507-4G11 | RR42_RS06775 | | hypothetical protein | insig. | 38 | 95 |
| Synechococcus elongatus PCC 7942 | Synpcc7942_1377 | | metal dependent phosphohydrolase | strong | 36 | 71 |
| Kangiella aquimarina DSM 16071 | B158DRAFT_0574 | | (p)ppGpp synthetase, RelA/SpoT family | no data | 33 | 72 |
| Rhizobium sp. OAE497 | ABIE40_RS06050 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 35 | 71 |
| Sinorhizobium meliloti 1021 | SMc02659 | | GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase) protein | strong | 35 | 71 |
| Rahnella sp. WP5 | EX31_RS15810 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | sig. | 34 | 73 |
| Serratia liquefaciens MT49 | IAI46_00415 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | insig. | 37 | 69 |
| Alteromonas macleodii MIT1002 | MIT1002_00108 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | strong | 35 | 70 |
| Magnetospirillum magneticum AMB-1 | AMB_RS11400 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | no data | 33 | 97 |
| Caulobacter crescentus NA1000 | CCNA_01622 | | Rsh ppGpp hydrolase-synthetase | strong | 36 | 71 |
| Caulobacter crescentus NA1000 Δfur | CCNA_01622 | | Rsh ppGpp hydrolase-synthetase | cofit | 36 | 71 |
| Ralstonia solanacearum IBSBF1503 | RALBFv3_RS03315 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 34 | 75 |
| Ralstonia solanacearum UW163 | UW163_RS10410 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | insig. | 34 | 75 |
| Marinobacter adhaerens HP15 | HP15_305 | | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 35 | 74 |
| Ralstonia solanacearum PSI07 | RPSI07_RS13870 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | cofit | 34 | 75 |
| Dechlorosoma suillum PS | Dsui_0500 | | (p)ppGpp synthetase, RelA/SpoT family | strong | 34 | 71 |
| Burkholderia phytofirmans PsJN | BPHYT_RS15305 | | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 34 | 71 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS14485 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 34 | 71 |
| Erwinia tracheiphila SCR3 | LU632_RS22200 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | insig. | 35 | 73 |
| Vibrio cholerae E7946 ATCC 55056 | CSW01_13675 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase | insig. | 37 | 73 |
| Klebsiella michiganensis M5al | BWI76_RS27430 | | (p)ppGpp synthetase | strong | 34 | 73 |
| Serratia liquefaciens MT49 | IAI46_24895 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | insig. | 34 | 73 |
| Pantoea sp. MT58 | IAI47_00510 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | sig. | 34 | 73 |
| Bacteroides thetaiotaomicron VPI-5482 | BT3998 | | GTP pyrophosphokinase (NCBI ptt file) | no data | 32 | 75 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS15610 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 34 | 71 |
| Bosea sp. OAE506 | ABIE41_RS19890 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 34 | 74 |
| Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_04004 | | (p)ppGpp synthetase I, SpoT/RelA | strong | 34 | 71 |
| Paraburkholderia graminis OAS925 | ABIE53_003230 | | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 34 | 71 |
| Bacteroides ovatus ATCC 8483 | BACOVA_04817 | | RelA/SpoT family protein | no data | 32 | 75 |
| Ralstonia solanacearum GMI1000 | RS_RS10800 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | no data | 35 | 71 |
| Escherichia coli BL21 | ECD_03507 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | sig. | 34 | 73 |
| Dickeya dadantii 3937 | DDA3937_RS00180 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | no data | 34 | 73 |
| Dickeya dianthicola 67-19 | HGI48_RS21180 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | no data | 34 | 73 |
| Dickeya dianthicola ME23 | DZA65_RS22150 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | no data | 34 | 73 |
| Escherichia fergusonii Becca | EFB2_00138 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | insig. | 34 | 73 |
| Escherichia coli ECOR27 | NOLOHH_07435 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | cofit | 34 | 73 |
| Escherichia coli ECOR38 | HEPCGN_14375 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | cofit | 34 | 73 |
| Escherichia coli ECRC100 | OKFHMN_15555 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | cofit | 34 | 73 |
| Escherichia coli ECRC101 | MCAODC_06065 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | insig. | 34 | 73 |
| Escherichia coli ECRC102 | NIAGMN_13315 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | insig. | 34 | 73 |
| Escherichia coli ECRC62 | BNILDI_04080 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | cofit | 34 | 73 |
| Escherichia coli ECRC98 | JDDGAC_19180 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | insig. | 34 | 73 |
| Escherichia coli ECRC99 | KEDOAH_12590 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | no data | 34 | 73 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00051 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | cofit | 34 | 73 |
| Escherichia coli Nissle 1917 | ECOLIN_RS20790 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | strong | 34 | 73 |
| Enterobacter asburiae PDN3 | EX28DRAFT_3899 | | (p)ppGpp synthetase, RelA/SpoT family | sig. | 34 | 73 |
| Escherichia coli BW25113 | b3650 | spoT | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) | strong | 34 | 73 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF357 | | 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 | strong | 34 | 73 |
| Pectobacterium carotovorum WPP14 | HER17_RS21385 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | cofit | 34 | 73 |
| Ralstonia sp. UNC404CL21Col | ABZR87_RS15225 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 34 | 75 |
| Parabacteroides merdae CL09T00C40 | HMPREF1078_RS04420 | | RelA/SpoT family protein | strong | 32 | 74 |
| Bacteroides stercoris CC31F | HMPREF1181_RS09205 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | no data | 32 | 75 |
| Rhodospirillum rubrum S1H | Rru_A1856 | | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA (NCBI) | no data | 35 | 71 |
| Enterobacter sp. TBS_079 | MPMX20_00086 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | strong | 34 | 73 |
| Magnetospirillum magneticum AMB-1 | AMB_RS08605 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | cofit | 34 | 83 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_1293 | | (p)ppGpp synthetase, RelA/SpoT family | strong | 33 | 79 |
| Bifidobacterium breve UCC2003 | BBR_RS16410 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | no data | 37 | 71 |
| Variovorax sp. SCN45 | GFF2375 | | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II | no data | 37 | 74 |