| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Xanthomonas campestris pv. campestris strain 8004 | 1.0 | Xcc-8004.3403.1 | | Fumarate hydratase class II (EC 4.2.1.2) | 1.0 | Xcc-8004.1053.1 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | 0.42 | 15 |
| Lysobacter sp. OAE881 | 0.77 | ABIE51_RS09015 | | class II fumarate hydratase | 0.44 | ABIE51_RS17585 | | 3-isopropylmalate dehydrogenase | low | > 62 |
| Rhodanobacter sp. FW510-T8 | 0.71 | OKGIIK_06345 | aspA | aspartate ammonia-lyase | 0.41 | OKGIIK_13595 | leuB | 3-isopropylmalate dehydrogenase | low | > 52 |
| Rhodanobacter denitrificans MT42 | 0.70 | LRK55_RS00660 | | class II fumarate hydratase | 0.42 | LRK55_RS09965 | | 3-isopropylmalate dehydrogenase | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.70 | LRK54_RS00885 | | class II fumarate hydratase | 0.41 | LRK54_RS10325 | | 3-isopropylmalate dehydrogenase | low | > 59 |
| Dyella japonica UNC79MFTsu3.2 | 0.70 | ABZR86_RS05855 | | class II fumarate hydratase | 0.39 | ABZR86_RS15950 | | 3-isopropylmalate dehydrogenase | low | > 74 |
| Pseudomonas simiae WCS417 | 0.60 | PS417_04305 | | aspartate ammonia-lyase | 0.79 | PS417_18585 | | 3-isopropylmalate dehydrogenase | low | > 88 |
| Vibrio cholerae E7946 ATCC 55056 | 0.60 | CSW01_07895 | | class II fumarate hydratase | 0.48 | CSW01_12600 | | 3-isopropylmalate dehydrogenase | low | > 62 |
| Pseudomonas fluorescens GW456-L13 | 0.59 | PfGW456L13_5022 | | Fumarate hydratase class II (EC 4.2.1.2) | 0.79 | PfGW456L13_3945 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | low | > 87 |
| Pseudomonas fluorescens FW300-N1B4 | 0.58 | Pf1N1B4_1088 | | Fumarate hydratase class II (EC 4.2.1.2) | 0.78 | Pf1N1B4_12 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | — | — |
| Pseudomonas fluorescens SBW25 | 0.58 | PFLU_RS04360 | | class II fumarate hydratase | 0.79 | PFLU_RS20565 | | 3-isopropylmalate dehydrogenase | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.58 | PFLU_RS04360 | | class II fumarate hydratase | 0.79 | PFLU_RS20565 | | 3-isopropylmalate dehydrogenase | low | > 109 |
| Pseudomonas putida KT2440 | 0.58 | PP_0944 | | fumarate hydratase (class 2) | 0.78 | PP_1988 | | 3-isopropylmalate dehydrogenase | low | > 96 |
| Pseudomonas sp. RS175 | 0.58 | PFR28_00165 | | Fumarate hydratase class II | 0.78 | PFR28_02821 | | 3-isopropylmalate dehydrogenase | low | > 88 |
| Pseudomonas fluorescens FW300-N2C3 | 0.57 | AO356_07075 | | aspartate ammonia-lyase | 0.79 | AO356_21415 | | 3-isopropylmalate dehydrogenase | low | > 104 |
| Pseudomonas fluorescens FW300-N2E2 | 0.57 | Pf6N2E2_3276 | | Fumarate hydratase class II (EC 4.2.1.2) | 0.79 | Pf6N2E2_66 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | low | > 103 |
| Shewanella amazonensis SB2B | 0.56 | Sama_0822 | | fumarate hydratase (RefSeq) | 0.47 | Sama_0336 | | 3-isopropylmalate dehydrogenase (RefSeq) | low | > 62 |
| Marinobacter adhaerens HP15 | 0.56 | HP15_3132 | | fumarate hydratase class II | 0.66 | HP15_1832 | | 3-isopropylmalate dehydrogenase | low | > 73 |
| Shewanella loihica PV-4 | 0.55 | Shew_0068 | | fumarate lyase (RefSeq) | 0.47 | Shew_3471 | | 3-isopropylmalate dehydrogenase (RefSeq) | low | > 60 |
| Alteromonas macleodii MIT1002 | 0.53 | MIT1002_03167 | | Fumarate hydratase class II | 0.46 | MIT1002_00948 | | 3-isopropylmalate dehydrogenase | low | > 70 |
| Kangiella aquimarina DSM 16071 | 0.49 | B158DRAFT_1200 | | fumarase, class II (EC 4.2.1.2) | 0.65 | B158DRAFT_1322 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | low | > 40 |
| Mycobacterium tuberculosis H37Rv | 0.48 | Rv1098c | | Probable fumarase Fum (fumarate hydratase) | 0.26 | Rv2995c | | Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) | — | — |
| Acinetobacter radioresistens SK82 | 0.48 | MPMX26_01446 | | Fumarate hydratase class II | 0.67 | MPMX26_00348 | | 3-isopropylmalate dehydrogenase | low | > 36 |
| Escherichia coli Nissle 1917 | 0.46 | ECOLIN_RS08995 | | class II fumarate hydratase | 0.47 | ECOLIN_RS00395 | | 3-isopropylmalate dehydrogenase | — | — |
| Escherichia fergusonii Becca | 0.46 | EFB2_02381 | | Fumarate hydratase class II | 0.47 | EFB2_03972 | | 3-isopropylmalate dehydrogenase | low | > 86 |
| Escherichia coli ECOR38 | 0.46 | HEPCGN_06025 | fumC | class II fumarate hydratase | 0.47 | HEPCGN_08700 | leuB | 3-isopropylmalate dehydrogenase | low | > 87 |
| Escherichia coli ECOR27 | 0.46 | NOLOHH_18155 | fumC | class II fumarate hydratase | 0.47 | NOLOHH_03065 | leuA | 2-isopropylmalate synthase | low | > 75 |
| Escherichia coli BL21 | 0.46 | ECD_01580 | | fumarate hydratase (fumarase C),aerobic Class II | 0.47 | ECD_00075 | | 3-isopropylmalate dehydrogenase, NAD(+)-dependent | — | — |
| Escherichia coli ECRC98 | 0.45 | JDDGAC_02240 | fumC | class II fumarate hydratase | 0.47 | JDDGAC_14315 | leuB | 3-isopropylmalate dehydrogenase | low | > 86 |
| Escherichia coli ECRC100 | 0.45 | OKFHMN_27650 | fumC | class II fumarate hydratase | 0.47 | OKFHMN_10720 | leuB | 3-isopropylmalate dehydrogenase | low | > 80 |
| Escherichia coli ECRC102 | 0.45 | NIAGMN_00425 | fumC | class II fumarate hydratase | 0.47 | NIAGMN_08570 | leuB | 3-isopropylmalate dehydrogenase | — | — |
| Escherichia coli BW25113 | 0.45 | b1611 | fumC | fumarate hydratase (NCBI) | 0.47 | b0073 | leuB | 3-isopropylmalate dehydrogenase (VIMSS) | low | > 76 |
| Escherichia coli ECRC99 | 0.45 | KEDOAH_00455 | fumC | class II fumarate hydratase | 0.47 | KEDOAH_17435 | leuB | 3-isopropylmalate dehydrogenase | — | — |
| Escherichia coli ECRC62 | 0.45 | BNILDI_16945 | fumC | class II fumarate hydratase | 0.47 | BNILDI_08545 | leuA | 2-isopropylmalate synthase | low | > 75 |
| Escherichia coli ECRC101 | 0.45 | MCAODC_17760 | fumC | class II fumarate hydratase | 0.47 | MCAODC_01235 | leuB | 3-isopropylmalate dehydrogenase | low | > 87 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.45 | OHPLBJKB_02115 | | Fumarate hydratase class II | 0.47 | OHPLBJKB_03584 | | 3-isopropylmalate dehydrogenase | low | > 73 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.45 | H281DRAFT_04314 | | fumarase, class II | 0.58 | H281DRAFT_06072 | | 3-isopropylmalate dehydrogenase | low | > 103 |
| Ralstonia solanacearum PSI07 | 0.45 | RPSI07_RS05900 | | class II fumarate hydratase | 0.58 | RPSI07_RS14705 | | 3-isopropylmalate dehydrogenase | low | > 81 |
| Sinorhizobium meliloti 1021 | 0.45 | SMc00149 | | fumarate hydratase | 0.52 | SMc04405 | | 3-isopropylmalate dehydrogenase | — | — |
| Enterobacter asburiae PDN3 | 0.44 | EX28DRAFT_1608 | | fumarase, class II (EC 4.2.1.2) | 0.49 | EX28DRAFT_3669 | | 3-isopropylmalate dehydrogenase | low | > 76 |
| Paraburkholderia graminis OAS925 | 0.44 | ABIE53_003084 | | fumarate hydratase class II | 0.58 | ABIE53_004804 | | 3-isopropylmalate dehydrogenase | low | > 113 |
| Ralstonia solanacearum UW163 | 0.44 | UW163_RS21470 | | class II fumarate hydratase | 0.58 | UW163_RS11115 | | 3-isopropylmalate dehydrogenase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.44 | RALBFv3_RS17680 | | class II fumarate hydratase | 0.58 | RALBFv3_RS02610 | | 3-isopropylmalate dehydrogenase | — | — |
| Ralstonia sp. UNC404CL21Col | 0.44 | ABZR87_RS18630 | | class II fumarate hydratase | 0.58 | ABZR87_RS14530 | | 3-isopropylmalate dehydrogenase | low | > 80 |
| Serratia liquefaciens MT49 | 0.44 | IAI46_11655 | | class II fumarate hydratase | 0.48 | IAI46_03350 | | 3-isopropylmalate dehydrogenase | low | > 86 |
| Klebsiella michiganensis M5al | 0.44 | BWI76_RS16270 | | fumarate hydratase, class II | 0.48 | BWI76_RS04675 | | 3-isopropylmalate dehydrogenase | low | > 92 |
| Ralstonia solanacearum GMI1000 | 0.44 | RS_RS23320 | | class II fumarate hydratase | 0.59 | RS_RS09990 | | 3-isopropylmalate dehydrogenase | low | > 80 |
| Rahnella sp. WP5 | 0.44 | EX31_RS06965 | | class II fumarate hydratase | 0.48 | EX31_RS03685 | | 3-isopropylmalate dehydrogenase | low | > 89 |
| Azospirillum sp. SherDot2 | 0.44 | MPMX19_01424 | | Fumarate hydratase class II | 0.52 | MPMX19_00607 | | 3-isopropylmalate dehydrogenase | low | > 112 |
| Rhodopseudomonas palustris CGA009 | 0.44 | TX73_018130 | | class II fumarate hydratase | 0.48 | TX73_001175 | | 3-isopropylmalate dehydrogenase | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.44 | Ga0059261_1040 | | fumarase, class II (EC 4.2.1.2) | 0.53 | Ga0059261_3190 | | 3-isopropylmalate dehydrogenase | low | > 68 |
| Enterobacter sp. TBS_079 | 0.44 | MPMX20_02022 | | Fumarate hydratase class II | 0.48 | MPMX20_00768 | | 3-isopropylmalate dehydrogenase | low | > 85 |
| Paraburkholderia sabiae LMG 24235 | 0.44 | QEN71_RS04360 | | class II fumarate hydratase | 0.57 | QEN71_RS17620 | | 3-isopropylmalate dehydrogenase | low | > 153 |
| Burkholderia phytofirmans PsJN | 0.44 | BPHYT_RS14615 | | fumarate hydratase | 0.58 | BPHYT_RS33900 | | 3-isopropylmalate dehydrogenase | low | > 109 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.44 | GFF1806 | | Fumarate hydratase class II (EC 4.2.1.2) | 0.47 | GFF165 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | low | > 78 |
| Erwinia tracheiphila SCR3 | 0.43 | LU632_RS12335 | fumC | class II fumarate hydratase | 0.44 | LU632_RS02875 | leuB | 3-isopropylmalate dehydrogenase | low | > 74 |
| Pantoea sp. MT58 | 0.43 | IAI47_10335 | | class II fumarate hydratase | 0.45 | IAI47_16005 | | 3-isopropylmalate dehydrogenase | low | > 76 |
| Dickeya dadantii 3937 | 0.43 | DDA3937_RS10655 | | class II fumarate hydratase | 0.47 | DDA3937_RS18120 | | 3-isopropylmalate dehydrogenase | low | > 74 |
| Dechlorosoma suillum PS | 0.43 | Dsui_0926 | | fumarate hydratase, class II | 0.62 | Dsui_3198 | | 3-isopropylmalate dehydrogenase | — | — |
| Dickeya dianthicola 67-19 | 0.43 | HGI48_RS10655 | | class II fumarate hydratase | 0.47 | HGI48_RS18060 | | 3-isopropylmalate dehydrogenase | low | > 71 |
| Pectobacterium carotovorum WPP14 | 0.43 | HER17_RS10755 | | class II fumarate hydratase | 0.47 | HER17_RS03080 | | 3-isopropylmalate dehydrogenase | low | > 75 |
| Dickeya dianthicola ME23 | 0.43 | DZA65_RS11125 | | class II fumarate hydratase | 0.47 | DZA65_RS19205 | | 3-isopropylmalate dehydrogenase | low | > 75 |
| Herbaspirillum seropedicae SmR1 | 0.42 | HSERO_RS07610 | | fumarate hydratase | 0.59 | HSERO_RS16500 | | 3-isopropylmalate dehydrogenase | low | > 78 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.42 | GFF4101 | | Fumarate hydratase class II (EC 4.2.1.2) | 0.59 | GFF3360 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | low | > 90 |
| Variovorax sp. OAS795 | 0.42 | ABID97_RS17545 | | class II fumarate hydratase | 0.59 | ABID97_RS08455 | | 3-isopropylmalate dehydrogenase | — | — |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.42 | A4249_RS05005 | | class II fumarate hydratase | 0.41 | A4249_RS09995 | | 3-isopropylmalate dehydrogenase | — | — |
| Azospirillum brasilense Sp245 | 0.42 | AZOBR_RS06120 | | fumarate hydratase | 0.51 | AZOBR_RS14130 | | 3-isopropylmalate dehydrogenase | 0.38 | 50 |
| Rhizobium sp. OAE497 | 0.42 | ABIE40_RS10540 | | class II fumarate hydratase | 0.52 | ABIE40_RS19050 | | 3-isopropylmalate dehydrogenase | low | > 107 |
| Variovorax sp. SCN45 | 0.42 | GFF479 | | Fumarate hydratase class II (EC 4.2.1.2) | 0.59 | GFF3888 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | low | > 127 |
| Acidovorax sp. GW101-3H11 | 0.42 | Ac3H11_943 | | Fumarate hydratase class II (EC 4.2.1.2) | 0.59 | Ac3H11_1528 | | 3-isopropylmalate dehydrogenase (EC 1.1.1.85) | low | > 79 |
| Magnetospirillum magneticum AMB-1 | 0.42 | AMB_RS18480 | | class II fumarate hydratase | 0.52 | AMB_RS20570 | | 3-isopropylmalate dehydrogenase | — | — |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.42 | DVU0080 | fumC | fumarate hydratase, class II (TIGR) | 0.53 | DVU2985 | leuB | 3-isopropylmalate dehydrogenase (TIGR) | low | > 55 |
| Castellaniella sp019104865 MT123 | 0.42 | ABCV34_RS03655 | | class II fumarate hydratase | 0.60 | ABCV34_RS04280 | | 3-isopropylmalate dehydrogenase | low | > 48 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.41 | CA265_RS23855 | | fumarate hydratase, class II | 0.46 | CA265_RS15850 | | 3-isopropylmalate dehydrogenase | — | — |
| Rhodospirillum rubrum S1H | 0.41 | Rru_A2129 | | Fumarate hydratase, class II (NCBI) | 0.53 | Rru_A1191 | | 3-isopropylmalate dehydrogenase (NCBI) | low | > 58 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.41 | Psyr_3661 | | Fumarate hydratase, class II | 0.78 | Psyr_1985 | | 3-isopropylmalate dehydrogenase | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.41 | Psyr_3661 | | Fumarate hydratase, class II | 0.78 | Psyr_1985 | | 3-isopropylmalate dehydrogenase | low | > 86 |
| Synechococcus elongatus PCC 7942 | 0.41 | Synpcc7942_1007 | fumC | fumarate hydratase | 0.52 | Synpcc7942_1505 | leuB | 3-isopropylmalate dehydrogenase | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.41 | AO353_02150 | | fumarate hydratase | 0.77 | AO353_20635 | | 3-isopropylmalate dehydrogenase | low | > 101 |
| Pseudomonas sp. S08-1 | 0.41 | OH686_21015 | | fumarate hydratase, class II | 0.81 | OH686_04470 | | 3-isopropylmalate dehydrogenase | low | > 80 |
| Agrobacterium fabrum C58 | 0.40 | Atu1616 | | fumarate hydratase | 0.52 | Atu2791 | | 3-isopropylmalate dehydrogenase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.40 | RR42_RS33090 | | fumarate hydratase | 0.58 | RR42_RS14385 | | 3-isopropylmalate dehydrogenase | low | > 128 |
| Dinoroseobacter shibae DFL-12 | 0.40 | Dshi_2334 | | fumarate hydratase, class II (RefSeq) | 0.55 | Dshi_0081 | | 3-isopropylmalate dehydrogenase (RefSeq) | — | — |
| Bosea sp. OAE506 | 0.40 | ABIE41_RS12805 | | class II fumarate hydratase | 0.49 | ABIE41_RS11860 | | 3-isopropylmalate dehydrogenase | — | — |
| Pseudomonas stutzeri RCH2 | 0.40 | Psest_2682 | | fumarate hydratase, class II | 0.80 | Psest_2589 | | 3-isopropylmalate dehydrogenase | low | > 67 |
| Phaeobacter inhibens DSM 17395 | 0.40 | PGA1_c13520 | | fumarate hydratase class II | 0.55 | PGA1_c29830 | | 3-isopropylmalate dehydrogenase LeuB | — | — |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.40 | ABZR88_RS20230 | | class II fumarate hydratase | 0.47 | ABZR88_RS11605 | | 3-isopropylmalate dehydrogenase | — | — |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.40 | CA264_17145 | | class II fumarate hydratase | 0.40 | CA264_09445 | | 3-isopropylmalate dehydrogenase | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.40 | CCNA_02194 | | fumarate hydratase | 0.48 | CCNA_00193 | | 3-isopropylmalate dehydrogenase | — | — |
| Caulobacter crescentus NA1000 | 0.40 | CCNA_02194 | | fumarate hydratase | 0.48 | CCNA_00193 | | 3-isopropylmalate dehydrogenase | — | — |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.39 | Echvi_1329 | | fumarate hydratase, class II | 0.41 | Echvi_2062 | | 3-isopropylmalate dehydrogenase | — | — |
| Desulfovibrio vulgaris Miyazaki F | 0.36 | DvMF_0565 | aspA | aspartate ammonia-lyase (RefSeq) | 0.57 | DvMF_1794 | | 3-isopropylmalate dehydrogenase (RefSeq) | low | > 51 |
| Phocaeicola vulgatus CL09T03C04 | 0.35 | HMPREF1058_RS06295 | | aspartate ammonia-lyase | 0.39 | HMPREF1058_RS14565 | | 3-isopropylmalate dehydrogenase | low | > 67 |
| Phocaeicola dorei CL03T12C01 | 0.35 | ABI39_RS20055 | | aspartate ammonia-lyase | 0.39 | ABI39_RS10215 | | 3-isopropylmalate dehydrogenase | low | > 72 |
| Bacteroides ovatus ATCC 8483 | 0.33 | BACOVA_01069 | | aspartate ammonia-lyase | 0.38 | BACOVA_04600 | | 3-isopropylmalate dehydrogenase | low | > 94 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.32 | BT2755 | | aspartate ammonia-lyase (NCBI ptt file) | 0.39 | BT1857 | | 3-isopropylmalate dehydrogenase (NCBI ptt file) | low | > 81 |
| Bacteroides stercoris CC31F | 0.32 | HMPREF1181_RS11250 | | aspartate ammonia-lyase | 0.40 | HMPREF1181_RS14125 | | 3-isopropylmalate dehydrogenase | low | > 56 |
Not shown: 1 genomes with orthologs for Xcc-8004.3403.1 only; 3 genomes with orthologs for Xcc-8004.1053.1 only