Conservation of cofitness between PP_4700 and PP_5095 in Pseudomonas putida KT2440

95 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_4700 pantothenate synthetase 1.0 PP_5095 pyrroline-5-carboxylate reductase 0.56 6
Pseudomonas sp. RS175 0.84 PFR28_03722 Pantothenate synthetase 0.86 PFR28_04243 Pyrroline-5-carboxylate reductase — —
Pseudomonas fluorescens FW300-N2C3 0.83 AO356_16055 pantoate--beta-alanine ligase 0.85 AO356_13420 pyrroline-5-carboxylate reductase — —
Pseudomonas fluorescens FW300-N2E2 0.83 Pf6N2E2_5152 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.84 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —
Pseudomonas fluorescens FW300-N2E3 0.83 AO353_14380 pantoate--beta-alanine ligase 0.85 AO353_08165 pyrroline-5-carboxylate reductase low > 101
Pseudomonas fluorescens GW456-L13 0.82 PfGW456L13_1520 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.84 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) low > 87
Pseudomonas fluorescens FW300-N1B4 0.81 Pf1N1B4_2853 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.84 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —
Pseudomonas fluorescens SBW25 0.80 PFLU_RS25755 pantoate--beta-alanine ligase 0.82 PFLU_RS28375 pyrroline-5-carboxylate reductase — —
Pseudomonas simiae WCS417 0.80 PS417_23915 pantoate--beta-alanine ligase 0.82 PS417_26730 pyrroline-5-carboxylate reductase low > 88
Pseudomonas fluorescens SBW25-INTG 0.80 PFLU_RS25755 pantoate--beta-alanine ligase 0.82 PFLU_RS28375 pyrroline-5-carboxylate reductase — —
Pseudomonas sp. S08-1 0.78 OH686_17240 pantoate--beta-alanine ligase 0.79 OH686_10980 pyrroline-5-carboxylate reductase — —
Pseudomonas syringae pv. syringae B728a 0.78 Psyr_0827 pantothenate synthetase 0.75 Psyr_0476 pyrroline-5-carboxylate reductase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.78 Psyr_0827 pantothenate synthetase 0.75 Psyr_0476 pyrroline-5-carboxylate reductase 0.62 34
Pseudomonas stutzeri RCH2 0.71 Psest_0995 pantoate--beta-alanine ligase 0.77 Psest_0283 pyrroline-5-carboxylate reductase — —
Marinobacter adhaerens HP15 0.63 HP15_323 pantothenate synthetase 0.42 HP15_287 pyrroline-5-carboxylate reductase — —
Shewanella amazonensis SB2B 0.55 Sama_0775 panC pantoate--beta-alanine ligase (RefSeq) 0.37 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) — —
Shewanella oneidensis MR-1 0.54 SO0869 panC pantoate--beta-alanine ligase (NCBI ptt file) 0.38 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) — —
Alteromonas macleodii MIT1002 0.54 MIT1002_03695 Pantothenate synthetase 0.39 MIT1002_03062 Pyrroline-5-carboxylate reductase — —
Shewanella sp. ANA-3 0.54 Shewana3_3409 panC pantoate--beta-alanine ligase (RefSeq) 0.37 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) — —
Shewanella loihica PV-4 0.53 Shew_3134 pantoate--beta-alanine ligase (RefSeq) 0.37 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) — —
Serratia liquefaciens MT49 0.53 IAI46_21245 pantoate--beta-alanine ligase 0.37 IAI46_21415 pyrroline-5-carboxylate reductase low > 86
Escherichia fergusonii Becca 0.53 EFB2_03911 Pantothenate synthetase 0.28 EFB2_03670 Pyrroline-5-carboxylate reductase low > 86
Escherichia coli ECOR38 0.52 HEPCGN_08380 panC pantoate--beta-alanine ligase 0.28 HEPCGN_07250 proC pyrroline-5-carboxylate reductase low > 85
Escherichia coli ECRC102 0.52 NIAGMN_08255 panC pantoate--beta-alanine ligase 0.27 NIAGMN_06665 proC pyrroline-5-carboxylate reductase — —
Escherichia coli ECRC99 0.52 KEDOAH_17750 panC pantoate--beta-alanine ligase 0.27 KEDOAH_19355 proC pyrroline-5-carboxylate reductase — —
Escherichia coli ECRC98 0.52 JDDGAC_14000 panC pantoate--beta-alanine ligase 0.27 JDDGAC_12265 proC pyrroline-5-carboxylate reductase — —
Escherichia coli ECRC101 0.52 MCAODC_00920 panC pantoate--beta-alanine ligase 0.27 MCAODC_27835 proC pyrroline-5-carboxylate reductase — —
Escherichia coli ECRC101 0.52 OKFHMN_10405 panC pantoate--beta-alanine ligase 0.27 OKFHMN_08610 proC pyrroline-5-carboxylate reductase — —
Escherichia coli ECOR27 0.52 NOLOHH_02750 panC pantoate--beta-alanine ligase 0.27 NOLOHH_01535 proC pyrroline-5-carboxylate reductase low > 57
Escherichia coli HS(pFamp)R (ATCC 700891) 0.52 OHPLBJKB_03528 Pantothenate synthetase 0.27 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase low > 73
Escherichia coli BW25113 0.52 b0133 panC pantoate--beta-alanine ligase (NCBI) 0.27 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.33 65
Escherichia coli BL21 0.52 ECD_00132 pantothenate synthetase 0.27 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding low > 60
Escherichia coli ECRC62 0.52 BNILDI_08920 panC pantoate--beta-alanine ligase 0.27 BNILDI_22950 proC pyrroline-5-carboxylate reductase — —
Kangiella aquimarina DSM 16071 0.51 B158DRAFT_0062 pantoate--beta-alanine ligase 0.39 B158DRAFT_0197 pyrroline-5-carboxylate reductase — —
Pectobacterium carotovorum WPP14 0.51 HER17_RS05555 pantoate--beta-alanine ligase 0.36 HER17_RS03805 pyrroline-5-carboxylate reductase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.51 GFF92 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.27 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) low > 78
Dickeya dianthicola ME23 0.51 DZA65_RS17160 pantoate--beta-alanine ligase 0.38 DZA65_RS18440 pyrroline-5-carboxylate reductase — —
Dickeya dadantii 3937 0.51 DDA3937_RS15960 pantoate--beta-alanine ligase 0.38 DDA3937_RS17305 pyrroline-5-carboxylate reductase low > 74
Klebsiella michiganensis M5al 0.51 BWI76_RS04990 pantoate--beta-alanine ligase 0.27 BWI76_RS06170 pyrroline-5-carboxylate reductase — —
Dyella japonica UNC79MFTsu3.2 0.51 ABZR86_RS00820 pantoate--beta-alanine ligase 0.42 ABZR86_RS10425 pyrroline-5-carboxylate reductase — —
Erwinia tracheiphila SCR3 0.50 LU632_RS20105 panC pantoate--beta-alanine ligase 0.29 LU632_RS18995 proC pyrroline-5-carboxylate reductase low > 74
Rhodanobacter denitrificans MT42 0.50 LRK55_RS14835 pantoate--beta-alanine ligase 0.41 LRK55_RS04030 pyrroline-5-carboxylate reductase — —
Dickeya dianthicola 67-19 0.50 HGI48_RS16075 pantoate--beta-alanine ligase 0.38 HGI48_RS17350 pyrroline-5-carboxylate reductase — —
Vibrio cholerae E7946 ATCC 55056 0.50 CSW01_03130 pantoate--beta-alanine ligase 0.38 CSW01_02450 pyrroline-5-carboxylate reductase — —
Rhodanobacter denitrificans FW104-10B01 0.50 LRK54_RS15120 pantoate--beta-alanine ligase 0.41 LRK54_RS04260 pyrroline-5-carboxylate reductase — —
Magnetospirillum magneticum AMB-1 0.50 AMB_RS22115 pantoate--beta-alanine ligase 0.28 AMB_RS02820 pyrroline-5-carboxylate reductase — —
Pantoea sp. MT58 0.50 IAI47_15660 pantoate--beta-alanine ligase 0.28 IAI47_14945 pyrroline-5-carboxylate reductase low > 76
Rahnella sp. WP5 0.49 EX31_RS03285 pantoate--beta-alanine ligase 0.38 EX31_RS02690 pyrroline-5-carboxylate reductase low > 89
Acinetobacter radioresistens SK82 0.49 MPMX26_00546 Pantothenate synthetase 0.46 MPMX26_00572 Pyrroline-5-carboxylate reductase — —
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_03890 panC pantoate--beta-alanine ligase 0.41 OKGIIK_11135 proC pyrroline-5-carboxylate reductase low > 52
Enterobacter asburiae PDN3 0.48 EX28DRAFT_3729 pantoate--beta-alanine ligase 0.27 EX28DRAFT_2585 pyrroline-5-carboxylate reductase low > 76
Enterobacter sp. TBS_079 0.47 MPMX20_00826 Pantothenate synthetase 0.27 MPMX20_00976 Pyrroline-5-carboxylate reductase low > 85
Rhodospirillum rubrum S1H 0.46 Rru_A3320 Cytidyltransferase-related (NCBI) 0.30 Rru_A3281 Delta 1-pyrroline-5-carboxylate reductase (NCBI) — —
Lysobacter sp. OAE881 0.46 ABIE51_RS08030 pantoate--beta-alanine ligase 0.48 ABIE51_RS16065 pyrroline-5-carboxylate reductase — —
Sphingomonas koreensis DSMZ 15582 0.46 Ga0059261_2453 pantoate--beta-alanine ligase 0.29 Ga0059261_3321 pyrroline-5-carboxylate reductase — —
Dechlorosoma suillum PS 0.45 Dsui_1470 pantoate--beta-alanine ligase 0.44 Dsui_0602 pyrroline-5-carboxylate reductase — —
Ralstonia solanacearum GMI1000 0.44 RS_RS11985 pantoate--beta-alanine ligase 0.37 RS_RS13440 pyrroline-5-carboxylate reductase — —
Variovorax sp. OAS795 0.44 ABID97_RS07430 pantoate--beta-alanine ligase 0.38 ABID97_RS01555 pyrroline-5-carboxylate reductase — —
Sinorhizobium meliloti 1021 0.44 SMc01880 pantoate--beta-alanine ligase 0.31 SMc02677 pyrroline-5-carboxylate reductase low > 103
Herbaspirillum seropedicae SmR1 0.44 HSERO_RS15520 pantoate--beta-alanine ligase 0.38 HSERO_RS18990 pyrroline-5-carboxylate reductase — —
Ralstonia solanacearum UW163 0.44 UW163_RS09235 pantoate--beta-alanine ligase 0.38 UW163_RS08045 pyrroline-5-carboxylate reductase — —
Ralstonia solanacearum IBSBF1503 0.44 RALBFv3_RS04435 pantoate--beta-alanine ligase 0.38 RALBFv3_RS05580 pyrroline-5-carboxylate reductase — —
Paraburkholderia bryophila 376MFSha3.1 0.43 H281DRAFT_00150 pantothenate synthetase 0.41 H281DRAFT_04679 pyrroline-5-carboxylate reductase — —
Variovorax sp. SCN45 0.43 GFF2578 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.38 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —
Dinoroseobacter shibae DFL-12 0.43 Dshi_2952 pantoate--beta-alanine ligase (RefSeq) 0.26 Dshi_2645 pyrroline-5-carboxylate reductase (RefSeq) — —
Agrobacterium fabrum C58 0.43 Atu3482 pantoate--beta-alanine ligase 0.34 Atu2209 pyrroline-5-carboxylate reductase 0.66 72
Ralstonia solanacearum PSI07 0.43 RPSI07_RS12935 pantoate--beta-alanine ligase 0.37 RPSI07_RS11720 pyrroline-5-carboxylate reductase — —
Caulobacter crescentus NA1000 0.43 CCNA_02247 pantoate-beta-alanine ligase 0.25 CCNA_00528 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) — —
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS25065 pantoate--beta-alanine ligase 0.41 QEN71_RS26600 pyrroline-5-carboxylate reductase — —
Caulobacter crescentus NA1000 Δfur 0.43 CCNA_02247 pantoate-beta-alanine ligase 0.25 CCNA_00528 pyrroline-5-carboxylate reductase — —
Ralstonia sp. UNC404CL21Col 0.43 ABZR87_RS00030 pantoate--beta-alanine ligase 0.39 ABZR87_RS01230 pyrroline-5-carboxylate reductase — —
Cupriavidus basilensis FW507-4G11 0.43 RR42_RS16055 pantothenate synthetase 0.39 RR42_RS17360 pyrroline-5-carboxylate reductase — —
Bosea sp. OAE506 0.43 ABIE41_RS14875 pantoate--beta-alanine ligase 0.24 ABIE41_RS11365 pyrroline-5-carboxylate reductase — —
Rhizobium sp. OAE497 0.42 ABIE40_RS09460 pantoate--beta-alanine ligase 0.33 ABIE40_RS13005 pyrroline-5-carboxylate reductase low > 107
Xanthomonas campestris pv. campestris strain 8004 0.42 Xcc-8004.3051.1 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.46 Xcc-8004.1710.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —
Castellaniella sp019104865 MT123 0.41 ABCV34_RS14585 pantoate--beta-alanine ligase 0.38 ABCV34_RS03610 pyrroline-5-carboxylate reductase — —
Paraburkholderia graminis OAS925 0.41 ABIE53_001260 pantoate--beta-alanine ligase 0.42 ABIE53_000840 pyrroline-5-carboxylate reductase — —
Burkholderia phytofirmans PsJN 0.41 BPHYT_RS04925 pantothenate synthetase 0.40 BPHYT_RS03490 pyrroline-5-carboxylate reductase — —
Rhodopseudomonas palustris CGA009 0.40 TX73_016310 pantoate--beta-alanine ligase 0.30 TX73_022630 pyrroline-5-carboxylate reductase — —
Azospirillum sp. SherDot2 0.40 MPMX19_04465 Pantothenate synthetase 0.29 MPMX19_01399 Pyrroline-5-carboxylate reductase — —
Phaeobacter inhibens DSM 17395 0.40 PGA1_c32040 pantothenate synthetase PanC 0.30 PGA1_c24700 pyrroline-5-carboxylate reductase ProC — —
Acidovorax sp. GW101-3H11 0.39 Ac3H11_3840 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.38 Ac3H11_788 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —
Desulfovibrio vulgaris Miyazaki F 0.39 DvMF_2942 panC pantoate--beta-alanine ligase (RefSeq) 0.23 DvMF_3161 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) — —
Bacteroides stercoris CC31F 0.38 HMPREF1181_RS06090 pantoate--beta-alanine ligase 0.20 HMPREF1181_RS03440 pyrroline-5-carboxylate reductase — —
Bacteroides ovatus ATCC 8483 0.38 BACOVA_05108 pantoate--beta-alanine ligase 0.23 BACOVA_03587 pyrroline-5-carboxylate reductase — —
Parabacteroides merdae CL09T00C40 0.38 HMPREF1078_RS14680 pantoate--beta-alanine ligase 0.17 HMPREF1078_RS10620 pyrroline-5-carboxylate reductase low > 61
Bacteroides thetaiotaomicron VPI-5482 0.38 BT4308 pantoate--beta-alanine ligase (NCBI ptt file) 0.22 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.37 ABZR88_RS18500 pantoate--beta-alanine ligase 0.19 ABZR88_RS09865 pyrroline-5-carboxylate reductase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.37 CA264_17615 pantoate--beta-alanine ligase 0.19 CA264_07730 pyrroline-5-carboxylate reductase — —
Desulfovibrio vulgaris Hildenborough JW710 0.37 DVU2448 panC pantoate--beta-alanine ligase (TIGR) 0.28 DVU2332 proC pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) low > 55
Hydrogenophaga sp. GW460-11-11-14-LB1 0.36 GFF1220 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.39 GFF2806 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) — —
Phocaeicola vulgatus CL09T03C04 0.35 HMPREF1058_RS18260 pantoate--beta-alanine ligase 0.20 HMPREF1058_RS08830 pyrroline-5-carboxylate reductase — —
Pedobacter sp. GW460-11-11-14-LB5 0.35 CA265_RS22700 pantoate--beta-alanine ligase 0.15 CA265_RS18505 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) — —
Phocaeicola dorei CL03T12C01 0.35 ABI39_RS14555 pantoate--beta-alanine ligase 0.20 ABI39_RS02960 pyrroline-5-carboxylate reductase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.34 Echvi_1527 pantoate--beta-alanine ligase 0.27 Echvi_2635 pyrroline-5-carboxylate reductase — —
Mycobacterium tuberculosis H37Rv 0.33 Rv3602c Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.25 Rv0500 Probable pyrroline-5-carboxylate reductase ProC (P5CR) (P5C reductase) — —

Not shown: 2 genomes with orthologs for PP_4700 only; 3 genomes with orthologs for PP_5095 only