Conservation of cofitness between PP_4700 and PP_0966 in Pseudomonas putida KT2440

96 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_4700 pantothenate synthetase 1.0 PP_0966 Histidinol dehydrogenase 0.48 18
Pseudomonas sp. RS175 0.84 PFR28_03722 Pantothenate synthetase 0.90 PFR28_00187 Histidinol dehydrogenase — —
Pseudomonas fluorescens FW300-N2C3 0.83 AO356_16055 pantoate--beta-alanine ligase 0.90 AO356_06965 histidinol dehydrogenase — —
Pseudomonas fluorescens FW300-N2E2 0.83 Pf6N2E2_5152 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.90 Pf6N2E2_3252 Histidinol dehydrogenase (EC 1.1.1.23) — —
Pseudomonas fluorescens FW300-N2E3 0.83 AO353_14380 pantoate--beta-alanine ligase 0.92 AO353_05110 histidinol dehydrogenase low > 101
Pseudomonas fluorescens GW456-L13 0.82 PfGW456L13_1520 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.91 PfGW456L13_5000 Histidinol dehydrogenase (EC 1.1.1.23) low > 87
Pseudomonas fluorescens FW300-N1B4 0.81 Pf1N1B4_2853 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.92 Pf1N1B4_1066 Histidinol dehydrogenase (EC 1.1.1.23) — —
Pseudomonas simiae WCS417 0.80 PS417_23915 pantoate--beta-alanine ligase 0.91 PS417_04420 histidinol dehydrogenase low > 88
Pseudomonas fluorescens SBW25-INTG 0.80 PFLU_RS25755 pantoate--beta-alanine ligase 0.92 PFLU_RS04470 histidinol dehydrogenase low > 109
Pseudomonas fluorescens SBW25 0.80 PFLU_RS25755 pantoate--beta-alanine ligase 0.92 PFLU_RS04470 histidinol dehydrogenase low > 109
Pseudomonas sp. S08-1 0.78 OH686_17240 pantoate--beta-alanine ligase 0.85 OH686_08470 Histidinol dehydrogenase — —
Pseudomonas syringae pv. syringae B728a 0.78 Psyr_0827 pantothenate synthetase 0.89 Psyr_4133 histidinol dehydrogenase 0.73 22
Pseudomonas syringae pv. syringae B728a ΔmexB 0.78 Psyr_0827 pantothenate synthetase 0.89 Psyr_4133 histidinol dehydrogenase 0.70 8
Pseudomonas stutzeri RCH2 0.71 Psest_0995 pantoate--beta-alanine ligase 0.85 Psest_3298 histidinol dehydrogenase — —
Marinobacter adhaerens HP15 0.63 HP15_323 pantothenate synthetase 0.70 HP15_2428 histidinol dehydrogenase — —
Shewanella amazonensis SB2B 0.55 Sama_0775 panC pantoate--beta-alanine ligase (RefSeq) 0.33 Sama_1942 hisD histidinol dehydrogenase (RefSeq) — —
Shewanella oneidensis MR-1 0.54 SO0869 panC pantoate--beta-alanine ligase (NCBI ptt file) 0.32 SO2073 hisD histidinol dehydrogenase (NCBI ptt file) — —
Alteromonas macleodii MIT1002 0.54 MIT1002_03695 Pantothenate synthetase 0.32 MIT1002_02633 Histidinol dehydrogenase — —
Shewanella sp. ANA-3 0.54 Shewana3_3409 panC pantoate--beta-alanine ligase (RefSeq) 0.33 Shewana3_1853 hisD histidinol dehydrogenase (RefSeq) — —
Shewanella loihica PV-4 0.53 Shew_3134 pantoate--beta-alanine ligase (RefSeq) 0.33 Shew_2198 histidinol dehydrogenase (RefSeq) — —
Serratia liquefaciens MT49 0.53 IAI46_21245 pantoate--beta-alanine ligase 0.30 IAI46_08210 histidinol dehydrogenase low > 86
Escherichia fergusonii Becca 0.53 EFB2_03911 Pantothenate synthetase 0.32 EFB2_01836 Histidinol dehydrogenase low > 86
Escherichia coli ECOR38 0.52 HEPCGN_08380 panC pantoate--beta-alanine ligase 0.32 HEPCGN_03220 hisD Histidinol dehydrogenase low > 85
Escherichia coli ECRC101 0.52 MCAODC_00920 panC pantoate--beta-alanine ligase 0.32 MCAODC_20425 hisD Histidinol dehydrogenase — —
Escherichia coli ECRC101 0.52 OKFHMN_10405 panC pantoate--beta-alanine ligase 0.32 OKFHMN_24515 hisD Histidinol dehydrogenase — —
Escherichia coli ECRC99 0.52 KEDOAH_17750 panC pantoate--beta-alanine ligase 0.32 KEDOAH_03635 hisD Histidinol dehydrogenase — —
Escherichia coli ECRC98 0.52 JDDGAC_14000 panC pantoate--beta-alanine ligase 0.32 JDDGAC_28625 hisD Histidinol dehydrogenase — —
Escherichia coli ECRC102 0.52 NIAGMN_08255 panC pantoate--beta-alanine ligase 0.32 NIAGMN_22460 hisD Histidinol dehydrogenase — —
Escherichia coli ECRC62 0.52 BNILDI_08920 panC pantoate--beta-alanine ligase 0.31 BNILDI_14740 hisD Histidinol dehydrogenase — —
Escherichia coli ECOR27 0.52 NOLOHH_02750 panC pantoate--beta-alanine ligase 0.32 NOLOHH_15830 hisD Histidinol dehydrogenase low > 57
Escherichia coli BL21 0.52 ECD_00132 pantothenate synthetase 0.32 ECD_01922 bifunctional histidinal dehydrogenase/ histidinol dehydrogenase low > 60
Escherichia coli BW25113 0.52 b0133 panC pantoate--beta-alanine ligase (NCBI) 0.32 b2020 hisD histidinol dehydrogenase (NCBI) 0.34 56
Escherichia coli HS(pFamp)R (ATCC 700891) 0.52 OHPLBJKB_03528 Pantothenate synthetase 0.32 OHPLBJKB_01680 Histidinol dehydrogenase low > 73
Kangiella aquimarina DSM 16071 0.51 B158DRAFT_0062 pantoate--beta-alanine ligase 0.28 B158DRAFT_2293 histidinol dehydrogenase — —
Pectobacterium carotovorum WPP14 0.51 HER17_RS05555 pantoate--beta-alanine ligase 0.31 HER17_RS12230 histidinol dehydrogenase 0.81 67
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.51 GFF92 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.32 GFF3912 Histidinol dehydrogenase (EC 1.1.1.23) low > 78
Dickeya dianthicola ME23 0.51 DZA65_RS17160 pantoate--beta-alanine ligase 0.32 DZA65_RS10055 histidinol dehydrogenase 0.89 11
Dyella japonica UNC79MFTsu3.2 0.51 ABZR86_RS00820 pantoate--beta-alanine ligase 0.31 ABZR86_RS06730 histidinol dehydrogenase — —
Dickeya dadantii 3937 0.51 DDA3937_RS15960 pantoate--beta-alanine ligase 0.33 DDA3937_RS09735 histidinol dehydrogenase 0.92 9
Klebsiella michiganensis M5al 0.51 BWI76_RS04990 pantoate--beta-alanine ligase 0.31 BWI76_RS18925 histidinol dehydrogenase low > 92
Erwinia tracheiphila SCR3 0.50 LU632_RS20105 panC pantoate--beta-alanine ligase 0.31 LU632_RS08945 hisD histidinol dehydrogenase low > 74
Rhodanobacter denitrificans MT42 0.50 LRK55_RS14835 pantoate--beta-alanine ligase 0.31 LRK55_RS01385 histidinol dehydrogenase low > 63
Dickeya dianthicola 67-19 0.50 HGI48_RS16075 pantoate--beta-alanine ligase 0.32 HGI48_RS09745 histidinol dehydrogenase low > 71
Vibrio cholerae E7946 ATCC 55056 0.50 CSW01_03130 pantoate--beta-alanine ligase 0.34 CSW01_05750 histidinol dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.50 LRK54_RS15120 pantoate--beta-alanine ligase 0.31 LRK54_RS01605 histidinol dehydrogenase — —
Magnetospirillum magneticum AMB-1 0.50 AMB_RS22115 pantoate--beta-alanine ligase 0.46 AMB_RS16905 histidinol dehydrogenase — —
Pantoea sp. MT58 0.50 IAI47_15660 pantoate--beta-alanine ligase 0.30 IAI47_07090 histidinol dehydrogenase 0.36 50
Rahnella sp. WP5 0.49 EX31_RS03285 pantoate--beta-alanine ligase 0.32 EX31_RS11440 histidinol dehydrogenase 0.42 51
Acinetobacter radioresistens SK82 0.49 MPMX26_00546 Pantothenate synthetase 0.57 MPMX26_02587 Histidinol dehydrogenase — —
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_03890 panC pantoate--beta-alanine ligase 0.32 OKGIIK_04950 hisD histidinol dehydrogenase low > 52
Enterobacter asburiae PDN3 0.48 EX28DRAFT_3729 pantoate--beta-alanine ligase 0.31 EX28DRAFT_0539 histidinol dehydrogenase low > 76
Enterobacter sp. TBS_079 0.47 MPMX20_00826 Pantothenate synthetase 0.31 MPMX20_03002 Histidinol dehydrogenase low > 85
Rhodospirillum rubrum S1H 0.46 Rru_A3320 Cytidyltransferase-related (NCBI) 0.47 Rru_A2771 Histidinol dehydrogenase (NCBI) — —
Lysobacter sp. OAE881 0.46 ABIE51_RS08030 pantoate--beta-alanine ligase 0.32 ABIE51_RS13325 histidinol dehydrogenase — —
Sphingomonas koreensis DSMZ 15582 0.46 Ga0059261_2453 pantoate--beta-alanine ligase 0.44 Ga0059261_1281 histidinol dehydrogenase — —
Dechlorosoma suillum PS 0.45 Dsui_1470 pantoate--beta-alanine ligase 0.63 Dsui_1411 histidinol dehydrogenase — —
Ralstonia solanacearum GMI1000 0.44 RS_RS11985 pantoate--beta-alanine ligase 0.62 RS_RS14790 histidinol dehydrogenase — —
Ralstonia solanacearum UW163 0.44 UW163_RS09235 pantoate--beta-alanine ligase 0.62 UW163_RS06770 histidinol dehydrogenase — —
Herbaspirillum seropedicae SmR1 0.44 HSERO_RS15520 pantoate--beta-alanine ligase 0.63 HSERO_RS20345 histidinol dehydrogenase — —
Sinorhizobium meliloti 1021 0.44 SMc01880 pantoate--beta-alanine ligase 0.47 SMc02307 histidinol dehydrogenase 0.75 4
Variovorax sp. OAS795 0.44 ABID97_RS07430 pantoate--beta-alanine ligase 0.64 ABID97_RS23160 histidinol dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.44 RALBFv3_RS04435 pantoate--beta-alanine ligase 0.62 RALBFv3_RS06845 histidinol dehydrogenase — —
Paraburkholderia bryophila 376MFSha3.1 0.43 H281DRAFT_00150 pantothenate synthetase 0.62 H281DRAFT_05652 histidinol dehydrogenase — —
Dinoroseobacter shibae DFL-12 0.43 Dshi_2952 pantoate--beta-alanine ligase (RefSeq) 0.45 Dshi_0979 Histidinol dehydrogenase (RefSeq) — —
Variovorax sp. SCN45 0.43 GFF2578 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.64 GFF5345 Histidinol dehydrogenase (EC 1.1.1.23) — —
Ralstonia solanacearum PSI07 0.43 RPSI07_RS12935 pantoate--beta-alanine ligase 0.63 RPSI07_RS10390 histidinol dehydrogenase — —
Agrobacterium fabrum C58 0.43 Atu3482 pantoate--beta-alanine ligase 0.44 Atu0537 histidinol dehydrogenase 0.76 64
Caulobacter crescentus NA1000 Δfur 0.43 CCNA_02247 pantoate-beta-alanine ligase 0.38 CCNA_02431 histidinol dehydrogenase — —
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS25065 pantoate--beta-alanine ligase 0.62 QEN71_RS27865 histidinol dehydrogenase — —
Caulobacter crescentus NA1000 0.43 CCNA_02247 pantoate-beta-alanine ligase 0.38 CCNA_02431 histidinol dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.43 RR42_RS16055 pantothenate synthetase 0.66 RR42_RS18915 histidinol dehydrogenase — —
Ralstonia sp. UNC404CL21Col 0.43 ABZR87_RS00030 pantoate--beta-alanine ligase 0.62 ABZR87_RS02500 histidinol dehydrogenase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.43 A4249_RS06825 pantoate--beta-alanine ligase 0.28 A4249_RS10695 histidinol dehydrogenase — —
Bosea sp. OAE506 0.43 ABIE41_RS14875 pantoate--beta-alanine ligase 0.45 ABIE41_RS24015 histidinol dehydrogenase low > 77
Rhizobium sp. OAE497 0.42 ABIE40_RS09460 pantoate--beta-alanine ligase 0.45 ABIE40_RS02725 histidinol dehydrogenase low > 107
Xanthomonas campestris pv. campestris strain 8004 0.42 Xcc-8004.3051.1 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.35 Xcc-8004.2948.1 Histidinol dehydrogenase (EC 1.1.1.23) — —
Paraburkholderia graminis OAS925 0.41 ABIE53_001260 pantoate--beta-alanine ligase 0.62 ABIE53_003701 histidinol dehydrogenase — —
Castellaniella sp019104865 MT123 0.41 ABCV34_RS14585 pantoate--beta-alanine ligase 0.56 ABCV34_RS11230 histidinol dehydrogenase — —
Burkholderia phytofirmans PsJN 0.41 BPHYT_RS04925 pantothenate synthetase 0.63 BPHYT_RS17710 histidinol dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.40 TX73_016310 pantoate--beta-alanine ligase 0.43 TX73_023540 histidinol dehydrogenase — —
Azospirillum sp. SherDot2 0.40 MPMX19_04465 Pantothenate synthetase 0.44 MPMX19_05543 Histidinol dehydrogenase — —
Phaeobacter inhibens DSM 17395 0.40 PGA1_c32040 pantothenate synthetase PanC 0.46 PGA1_c31190 histidinol dehydrogenase HisD — —
Acidovorax sp. GW101-3H11 0.39 Ac3H11_3840 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.63 Ac3H11_4724 Histidinol dehydrogenase (EC 1.1.1.23) — —
Desulfovibrio vulgaris Miyazaki F 0.39 DvMF_2942 panC pantoate--beta-alanine ligase (RefSeq) 0.39 DvMF_2814 hisD histidinol dehydrogenase (RefSeq) — —
Bacteroides stercoris CC31F 0.38 HMPREF1181_RS06090 pantoate--beta-alanine ligase 0.29 HMPREF1181_RS04860 histidinol dehydrogenase — —
Bacteroides ovatus ATCC 8483 0.38 BACOVA_05108 pantoate--beta-alanine ligase 0.28 BACOVA_01234 histidinol dehydrogenase — —
Parabacteroides merdae CL09T00C40 0.38 HMPREF1078_RS14680 pantoate--beta-alanine ligase 0.31 HMPREF1078_RS02450 histidinol dehydrogenase low > 61
Bacteroides thetaiotaomicron VPI-5482 0.38 BT4308 pantoate--beta-alanine ligase (NCBI ptt file) 0.28 BT0201 histidinol dehydrogenase (NCBI ptt file) — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.37 CA264_17615 pantoate--beta-alanine ligase 0.29 CA264_05030 histidinol dehydrogenase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.37 ABZR88_RS18500 pantoate--beta-alanine ligase 0.32 ABZR88_RS06880 histidinol dehydrogenase — —
Desulfovibrio vulgaris Hildenborough JW710 0.37 DVU2448 panC pantoate--beta-alanine ligase (TIGR) 0.41 DVU0796 hisD histidinol dehydrogenase (TIGR) low > 55
Hydrogenophaga sp. GW460-11-11-14-LB1 0.36 GFF1220 Pantoate--beta-alanine ligase (EC 6.3.2.1) 0.62 GFF1314 Histidinol dehydrogenase (EC 1.1.1.23) — —
Phocaeicola vulgatus CL09T03C04 0.35 HMPREF1058_RS18260 pantoate--beta-alanine ligase 0.29 HMPREF1058_RS15875 histidinol dehydrogenase — —
Pedobacter sp. GW460-11-11-14-LB5 0.35 CA265_RS22700 pantoate--beta-alanine ligase 0.33 CA265_RS03635 histidinol dehydrogenase — —
Phocaeicola dorei CL03T12C01 0.35 ABI39_RS14555 pantoate--beta-alanine ligase 0.29 ABI39_RS11835 histidinol dehydrogenase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.34 Echvi_1527 pantoate--beta-alanine ligase 0.30 Echvi_2459 histidinol dehydrogenase — —
Mycobacterium tuberculosis H37Rv 0.33 Rv3602c Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.28 Rv1599 Probable histidinol dehydrogenase HisD (HDH) — —

Not shown: 1 genomes with orthologs for PP_4700 only; 5 genomes with orthologs for PP_0966 only