Conservation of cofitness between HEPCGN_20570 and HEPCGN_08820 in Escherichia coli ECOR38

95 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR38 1.0 HEPCGN_20570 pdxJ pyridoxine 5'-phosphate synthase 1.0 HEPCGN_08820 pdxA 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 0.89 4
Escherichia coli ECRC101 1.00 MCAODC_11955 pdxJ pyridoxine 5'-phosphate synthase 0.99 MCAODC_01345 pdxA 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 0.75 9
Escherichia coli ECOR27 1.00 NOLOHH_13100 pdxJ pyridoxine 5'-phosphate synthase 1.00 NOLOHH_03175 pdxA 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 0.73 4
Escherichia coli ECRC98 1.00 JDDGAC_25090 pdxJ pyridoxine 5'-phosphate synthase 0.99 JDDGAC_14425 pdxA 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Escherichia coli BW25113 1.00 b2564 pdxJ pyridoxal phosphate biosynthetic protein (NCBI) 0.99 b0052 pdxA 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) 0.93 1
Escherichia coli ECRC102 1.00 NIAGMN_19195 pdxJ pyridoxine 5'-phosphate synthase 0.99 NIAGMN_08680 pdxA 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Escherichia coli ECRC100 1.00 OKFHMN_21425 pdxJ pyridoxine 5'-phosphate synthase 0.99 OKFHMN_10830 pdxA 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 0.79 7
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01143 'Pyridoxine 5'-phosphate synthase' transl_table=11 0.99 OHPLBJKB_03604 4-hydroxythreonine-4-phosphate dehydrogenase low > 73
Escherichia coli ECRC62 1.00 BNILDI_11900 pdxJ pyridoxine 5'-phosphate synthase 0.99 BNILDI_08430 pdxA 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 0.80 64
Escherichia coli BL21 1.00 ECD_02458 pyridoxine 5'-phosphate synthase 0.99 ECD_00056 4-hydroxy-L-threonine phosphate dehydrogenase, NAD-dependent — —
Escherichia coli ECRC99 0.99 KEDOAH_06795 pdxJ pyridoxine 5'-phosphate synthase 0.99 KEDOAH_17325 pdxA 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Escherichia fergusonii Becca 0.99 EFB2_01332 Pyridoxine 5'-phosphate synthase 0.99 EFB2_03991 4-hydroxythreonine-4-phosphate dehydrogenase low > 86
Escherichia coli Nissle 1917 0.98 ECOLIN_RS14515 pyridoxine 5'-phosphate synthase 0.99 ECOLIN_RS00290 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF2472 'Pyridoxine 5'-phosphate synthase (EC 2.6.99.2)' transl_table=11 0.92 GFF189 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) — —
Klebsiella michiganensis M5al 0.93 BWI76_RS21305 pyridoxine 5'-phosphate synthase 0.82 BWI76_RS04525 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Enterobacter sp. TBS_079 0.93 MPMX20_03435 Pyridoxine 5'-phosphate synthase 0.85 MPMX20_00748 4-hydroxythreonine-4-phosphate dehydrogenase 0.47 3
Enterobacter asburiae PDN3 0.92 EX28DRAFT_0082 pyridoxine 5'-phosphate synthase 0.85 EX28DRAFT_3646 4-hydroxythreonine-4-phosphate dehydrogenase — —
Pectobacterium carotovorum WPP14 0.81 HER17_RS05830 pyridoxine 5'-phosphate synthase 0.74 HER17_RS02965 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 0.84 48
Dickeya dianthicola 67-19 0.81 HGI48_RS15805 pyridoxine 5'-phosphate synthase 0.76 HGI48_RS18195 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 0.40 67
Dickeya dianthicola ME23 0.81 DZA65_RS16885 pyridoxine 5'-phosphate synthase 0.75 DZA65_RS19335 4-hydroxythreonine-4-phosphate dehydrogenase PdxA low > 75
Dickeya dadantii 3937 0.81 DDA3937_RS15720 pyridoxine 5'-phosphate synthase 0.76 DDA3937_RS18260 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 0.75 29
Pantoea sp. MT58 0.79 IAI47_04895 pyridoxine 5'-phosphate synthase 0.76 IAI47_16080 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 0.91 1
Rahnella sp. WP5 0.79 EX31_RS21850 pyridoxine 5'-phosphate synthase 0.74 EX31_RS03775 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 0.81 2
Serratia liquefaciens MT49 0.78 IAI46_19535 pyridoxine 5'-phosphate synthase 0.75 IAI46_03250 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Erwinia tracheiphila SCR3 0.76 LU632_RS15370 pdxJ pyridoxine 5'-phosphate synthase 0.77 LU632_RS02725 pdxA 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Kangiella aquimarina DSM 16071 0.75 B158DRAFT_2190 pyridoxine 5'-phosphate synthase 0.57 B158DRAFT_0789 4-hydroxythreonine-4-phosphate dehydrogenase — —
Alteromonas macleodii MIT1002 0.72 MIT1002_00791 Pyridoxine 5'-phosphate synthase 0.62 MIT1002_00782 4-hydroxythreonine-4-phosphate dehydrogenase — —
Vibrio cholerae E7946 ATCC 55056 0.71 CSW01_12440 pyridoxine 5'-phosphate synthase 0.62 CSW01_02330 4-hydroxythreonine-4-phosphate dehydrogenase — —
Shewanella sp. ANA-3 0.67 Shewana3_3023 pyridoxine 5'-phosphate synthase (RefSeq) 0.65 Shewana3_3208 4-hydroxythreonine-4-phosphate dehydrogenase (RefSeq) — —
Shewanella loihica PV-4 0.67 Shew_1057 pyridoxal phosphate biosynthetic protein PdxJ (RefSeq) 0.67 Shew_0880 4-hydroxythreonine-4-phosphate dehydrogenase (RefSeq) — —
Shewanella oneidensis MR-1 0.67 SO1351 pdxJ pyridoxal phosphate biosynthetic protein PdxJ (NCBI ptt file) 0.64 SO3638 pdxA pyridoxal phosphate biosynthetic protein PdxA (NCBI ptt file) — —
Shewanella amazonensis SB2B 0.66 Sama_0883 pyridoxine 5'-phosphate synthase (RefSeq) 0.65 Sama_2818 4-hydroxythreonine-4-phosphate dehydrogenase (RefSeq) — —
Paraburkholderia sabiae LMG 24235 0.64 QEN71_RS04625 pyridoxine 5'-phosphate synthase 0.47 QEN71_RS02125 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Paraburkholderia bryophila 376MFSha3.1 0.64 H281DRAFT_04365 pyridoxine 5'-phosphate synthase 0.48 H281DRAFT_04639 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) — —
Burkholderia phytofirmans PsJN 0.64 BPHYT_RS14355 pyridoxine 5'-phosphate synthase 0.49 BPHYT_RS03300 4-hydroxythreonine-4-phosphate dehydrogenase — —
Paraburkholderia graminis OAS925 0.64 ABIE53_003033 pyridoxine 5-phosphate synthase 0.49 ABIE53_000799 4-hydroxythreonine-4-phosphate dehydrogenase — —
Pseudomonas sp. RS175 0.63 PFR28_03520 'Pyridoxine 5'-phosphate synthase' transl_table=11 0.57 PFR28_04063 4-hydroxythreonine-4-phosphate dehydrogenase — —
Pseudomonas fluorescens FW300-N1B4 0.63 Pf1N1B4_889 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.59 Pf1N1B4_2529 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) — —
Pseudomonas sp. S08-1 0.63 OH686_20095 pyridoxine 5'-phosphate synthase 0.56 OH686_15045 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Pseudomonas putida KT2440 0.63 PP_1436 Pyridoxine 5'-phosphate synthase 0.58 PP_0402 4-hydroxythreonine-4-phosphate dehydrogenase — —
Pseudomonas fluorescens FW300-N2C3 0.63 AO356_17510 pyridoxine 5'-phosphate synthase 0.58 AO356_14340 4-hydroxythreonine-4-phosphate dehydrogenase — —
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_4837 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.60 PfGW456L13_1201 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.62 Psyr_3948 pyridoxine 5'-phosphate synthase 0.56 Psyr_4626 4-hydroxythreonine-4-phosphate dehydrogenase — —
Pseudomonas syringae pv. syringae B728a 0.62 Psyr_3948 pyridoxine 5'-phosphate synthase 0.56 Psyr_4626 4-hydroxythreonine-4-phosphate dehydrogenase — —
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_5429 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.58 Pf6N2E2_4806 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) — —
Pseudomonas stutzeri RCH2 0.61 Psest_3089 pyridoxine 5'-phosphate synthase 0.59 Psest_3667 4-hydroxythreonine-4-phosphate dehydrogenase — —
Pseudomonas fluorescens FW300-N2E3 0.61 AO353_04495 pyridoxine 5'-phosphate synthase 0.59 AO353_07310 4-hydroxythreonine-4-phosphate dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.61 RR42_RS14025 pyridoxine 5'-phosphate synthase 0.46 RR42_RS02780 4-hydroxythreonine-4-phosphate dehydrogenase — —
Pseudomonas simiae WCS417 0.61 PS417_05205 pyridoxine 5'-phosphate synthase 0.59 PS417_25805 4-hydroxythreonine-4-phosphate dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.60 PFLU_RS05275 pyridoxine 5'-phosphate synthase 0.59 PFLU_RS27460 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Marinobacter adhaerens HP15 0.60 HP15_787 pyridoxal phosphate biosynthetic protein PdxJ 0.55 HP15_3279 4-hydroxythreonine-4-phosphate dehydrogenase — —
Pseudomonas fluorescens SBW25 0.60 PFLU_RS05275 pyridoxine 5'-phosphate synthase 0.59 PFLU_RS27460 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Acinetobacter radioresistens SK82 0.60 MPMX26_02152 Pyridoxine 5'-phosphate synthase 0.51 MPMX26_00595 4-hydroxythreonine-4-phosphate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.58 RALBFv3_RS14500 pyridoxine 5'-phosphate synthase 0.49 RALBFv3_RS11750 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Ralstonia solanacearum UW163 0.58 UW163_RS11965 pyridoxine 5'-phosphate synthase 0.49 UW163_RS01835 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Ralstonia solanacearum GMI1000 0.57 RS_RS05280 pyridoxine 5'-phosphate synthase 0.49 RS_RS02575 4-hydroxythreonine-4-phosphate dehydrogenase — —
Ralstonia solanacearum PSI07 0.57 RPSI07_RS18960 pyridoxine 5'-phosphate synthase 0.49 RPSI07_RS21465 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Herbaspirillum seropedicae SmR1 0.55 HSERO_RS09675 pyridoxine 5'-phosphate synthase 0.46 HSERO_RS03535 4-hydroxythreonine-4-phosphate dehydrogenase — —
Azospirillum sp. SherDot2 0.55 MPMX19_00840 Pyridoxine 5'-phosphate synthase 0.32 MPMX19_00835 D-erythronate 4-phosphate dehydrogenase 0.67 1
Ralstonia sp. UNC404CL21Col 0.55 ABZR87_RS10220 pyridoxine 5'-phosphate synthase 0.48 ABZR87_RS07705 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Phaeobacter inhibens DSM 17395 0.55 PGA1_c01030 pyridoxine 5'-phosphate synthase PdxJ 0.31 PGA1_c19850 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Dinoroseobacter shibae DFL-12 0.54 Dshi_0196 pyridoxal phosphate biosynthetic protein PdxJ (RefSeq) 0.36 Dshi_1186 4-hydroxythreonine-4-phosphate dehydrogenase (RefSeq) — —
Azospirillum brasilense Sp245 0.54 AZOBR_RS22055 pyridoxine 5'-phosphate synthase 0.32 AZOBR_RS16370 4-hydroxythreonine-4-phosphate dehydrogenase low > 97
Dechlorosoma suillum PS 0.53 Dsui_2463 pyridoxine 5''-phosphate synthase 0.52 Dsui_1585 4-hydroxythreonine-4-phosphate dehydrogenase — —
Magnetospirillum magneticum AMB-1 0.53 AMB_RS11405 pyridoxine 5'-phosphate synthase 0.31 AMB_RS18815 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Bosea sp. OAE506 0.52 ABIE41_RS19905 pyridoxine 5'-phosphate synthase 0.30 ABIE41_RS20430 4-hydroxythreonine-4-phosphate dehydrogenase PdxA low > 77
Synechococcus elongatus PCC 7942 0.52 Synpcc7942_1194 pdxJ pyridoxal phosphate biosynthetic protein PdxJ 0.29 Synpcc7942_0804 pdxA 4-hydroxythreonine-4-phosphate dehydrogenase — —
Caulobacter crescentus NA1000 Δfur 0.52 CCNA_01626 pyridoxal phosphate biosynthetic protein pdxJ 0.31 CCNA_01758 4-hydroxythreonine-4-phosphate dehydrogenase — —
Caulobacter crescentus NA1000 0.52 CCNA_01626 pyridoxal phosphate biosynthetic protein pdxJ 0.31 CCNA_01758 4-hydroxythreonine-4-phosphate dehydrogenase — —
Desulfovibrio vulgaris Miyazaki F 0.51 DvMF_0281 pyridoxine 5'-phosphate synthase (RefSeq) 0.27 DvMF_0837 4-hydroxythreonine-4-phosphate dehydrogenase (RefSeq) 0.50 8
Rhodospirillum rubrum S1H 0.50 Rru_A1854 Pyridoxal phosphate biosynthetic protein PdxJ (NCBI) 0.27 Rru_A0432 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) 0.96 1
Sphingomonas koreensis DSMZ 15582 0.50 Ga0059261_2011 pyridoxine 5'-phosphate synthase 0.27 Ga0059261_0878 4-hydroxythreonine-4-phosphate dehydrogenase — —
Castellaniella sp019104865 MT123 0.49 ABCV34_RS04215 pyridoxine 5'-phosphate synthase 0.34 ABCV34_RS02270 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Rhodopseudomonas palustris CGA009 0.48 TX73_013960 pyridoxine 5'-phosphate synthase 0.30 TX73_015855 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 0.75 1
Brevundimonas sp. GW460-12-10-14-LB2 0.42 A4249_RS05520 pyridoxine 5'-phosphate synthase 0.29 A4249_RS06755 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Bacteroides stercoris CC31F 0.33 HMPREF1181_RS06645 pyridoxine 5'-phosphate synthase 0.29 HMPREF1181_RS05765 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Phocaeicola vulgatus CL09T03C04 0.33 HMPREF1058_RS08325 pyridoxine 5'-phosphate synthase 0.29 HMPREF1058_RS17035 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 0.93 2
Phocaeicola dorei CL03T12C01 0.33 ABI39_RS02500 pyridoxine 5'-phosphate synthase 0.29 ABI39_RS12955 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 0.91 2
Mucilaginibacter yixingensis YX-36 DSM 26809 0.31 ABZR88_RS01795 pyridoxine 5'-phosphate synthase 0.30 ABZR88_RS00055 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Agrobacterium fabrum C58 0.31 Atu2024 pyridoxal phosphate biosynthesis protein 0.34 Atu1104 pyridoxal phosphate biosynthesis protein — —
Parabacteroides merdae CL09T00C40 0.30 HMPREF1078_RS10265 pyridoxine 5'-phosphate synthase 0.24 HMPREF1078_RS14540 4-hydroxythreonine-4-phosphate dehydrogenase PdxA low > 61
Pedobacter sp. GW460-11-11-14-LB5 0.30 CA265_RS25170 pyridoxine 5'-phosphate synthase 0.31 CA265_RS18320 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.30 CA264_15275 pyridoxine 5'-phosphate synthase 0.28 CA264_03840 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.30 Echvi_0661 pyridoxine 5'-phosphate synthase 0.32 Echvi_0923 4-hydroxythreonine-4-phosphate dehydrogenase — —
Dyella japonica UNC79MFTsu3.2 0.29 ABZR86_RS15180 pyridoxine 5'-phosphate synthase 0.47 ABZR86_RS11265 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Rhodanobacter denitrificans MT42 0.29 LRK55_RS08205 pyridoxine 5'-phosphate synthase 0.50 LRK55_RS12045 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Rhodanobacter denitrificans FW104-10B01 0.29 LRK54_RS08440 pyridoxine 5'-phosphate synthase 0.50 LRK54_RS12310 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Sinorhizobium meliloti 1021 0.28 SMc01407 pyridoxine 5'-phosphate synthase 0.32 SMc00580 4-hydroxythreonine-4-phosphate dehydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.28 Xcc-8004.17.1 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.41 Xcc-8004.4270.1 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) 0.78 1
Rhodanobacter sp. FW510-T8 0.28 OKGIIK_15220 pyridoxine 5'-phosphate synthase 0.47 OKGIIK_11620 pdxA 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.27 GFF3349 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.27 GFF1297 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) — —
Lysobacter sp. OAE881 0.26 ABIE51_RS00810 pyridoxine 5'-phosphate synthase 0.46 ABIE51_RS05390 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Rhizobium sp. OAE497 0.26 ABIE40_RS11420 pyridoxine 5'-phosphate synthase 0.32 ABIE40_RS06395 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —
Acidovorax sp. GW101-3H11 0.25 Ac3H11_1563 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.28 Ac3H11_4747 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) — —
Variovorax sp. SCN45 0.23 GFF3873 Pyridoxine 5'-phosphate synthase (EC 2.6.99.2) 0.30 GFF5368 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) — —
Variovorax sp. OAS795 0.22 ABID97_RS08380 pyridoxine 5'-phosphate synthase 0.30 ABID97_RS25690 4-hydroxythreonine-4-phosphate dehydrogenase PdxA — —

Not shown: 3 genomes with orthologs for HEPCGN_20570 only; 1 genomes with orthologs for HEPCGN_08820 only