Conservation of cofitness between GFF1922 and GFF246 in Sphingobium sp. HT1-2

103 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF1922 Glycine cleavage system H protein 1.0 GFF246 Quinolinate synthetase (EC 2.5.1.72) low > 95
Sphingomonas koreensis DSMZ 15582 0.75 Ga0059261_3257 glycine cleavage system H protein 0.84 Ga0059261_0051 quinolinate synthetase (EC 2.5.1.72) — —
Azospirillum sp. SherDot2 0.72 MPMX19_01030 Glycine cleavage system H protein 0.36 MPMX19_05670 Quinolinate synthase A 0.51 4
Azospirillum brasilense Sp245 0.67 AZOBR_RS10465 glycine cleavage system protein H 0.33 AZOBR_RS18690 quinolinate synthetase — —
Xanthobacter sp. DMC5 0.64 GFF1877 Glycine cleavage system H protein 0.32 GFF1847 Quinolinate synthase A — —
Sinorhizobium meliloti 1021 0.63 SMc02048 glycine cleavage system protein H 0.32 SMc02601 quinolinate synthetase low > 103
Agrobacterium fabrum C58 0.63 Atu1463 glycine cleavage system component H 0.32 Atu4098 quinolinate synthetase 0.64 56
Brevundimonas sp. GW460-12-10-14-LB2 0.62 A4249_RS09330 glycine cleavage system protein GcvH 0.31 A4249_RS00620 quinolinate synthase NadA low > 48
Rhodospirillum rubrum S1H 0.62 Rru_A3050 Glycine cleavage H-protein (NCBI) 0.32 Rru_A1434 Quinolinate synthetase A (NCBI) low > 58
Rhizobium sp. OAE497 0.61 ABIE40_RS09945 glycine cleavage system protein GcvH 0.34 ABIE40_RS23255 quinolinate synthase NadA low > 107
Caulobacter crescentus NA1000 Δfur 0.57 CCNA_03464 glycine cleavage system H protein 0.31 CCNA_03006 quinolinate synthetase A — —
Caulobacter crescentus NA1000 0.57 CCNA_03464 glycine cleavage system H protein 0.31 CCNA_03006 quinolinate synthetase A — —
Magnetospirillum magneticum AMB-1 0.57 AMB_RS03930 glycine cleavage system protein H 0.66 AMB_RS19660 quinolinate synthase NadA — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.57 GFF5214 Glycine cleavage system H protein 0.38 GFF1216 Quinolinate synthetase (EC 2.5.1.72) low > 90
Acidovorax sp. GW101-3H11 0.57 Ac3H11_166 Glycine cleavage system H protein 0.38 Ac3H11_3837 Quinolinate synthetase (EC 2.5.1.72) low > 79
Variovorax sp. SCN45 0.56 GFF6477 Glycine cleavage system H protein 0.38 GFF2575 Quinolinate synthetase (EC 2.5.1.72) — —
Variovorax sp. OAS795 0.55 ABID97_RS19650 glycine cleavage system protein GcvH 0.39 ABID97_RS07415 quinolinate synthase NadA — —
Marinobacter adhaerens HP15 0.54 HP15_459 glycine cleavage H-protein, subgroup 0.38 HP15_2032 quinolinate synthetase complex, A subunit — —
Bacteroides thetaiotaomicron VPI-5482 0.54 BT2519 putative glycine cleavage system H protein (NCBI ptt file) 0.51 BT3164 quinolinate synthetase A (NCBI ptt file) low > 81
Shewanella amazonensis SB2B 0.53 Sama_2720 glycine cleavage system protein H (RefSeq) 0.39 Sama_1712 quinolinate synthetase (RefSeq) — —
Escherichia coli ECOR38 0.53 HEPCGN_18815 gcvH glycine cleavage system protein GcvH 0.40 HEPCGN_01515 nadA quinolinate synthase NadA low > 88
Phaeobacter inhibens DSM 17395 0.53 PGA1_c05560 glycine cleavage system protein GcvH 0.35 PGA1_c27790 quinolinate synthetase A low > 62
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.53 GFF3004 Glycine cleavage system H protein 0.39 GFF4 Quinolinate synthetase (EC 2.5.1.72) — —
Bacteroides ovatus ATCC 8483 0.53 BACOVA_01614 glycine cleavage system H protein 0.50 BACOVA_02839 quinolinate synthetase complex, A subunit low > 96
Escherichia coli ECOR27 0.53 NOLOHH_11440 gcvH glycine cleavage system protein GcvH 0.40 NOLOHH_23190 nadA quinolinate synthase NadA low > 76
Escherichia coli ECRC62 0.53 BNILDI_09975 gcvH glycine cleavage system protein GcvH 0.40 BNILDI_21185 nadA quinolinate synthase NadA low > 75
Escherichia coli BL21 0.52 ECD_02736 glycine cleavage complex lipoylprotein 0.40 ECD_00703 quinolinate synthase, subunit A low > 61
Escherichia coli BW25113 0.52 b2904 gcvH glycine cleavage system protein H (NCBI) 0.40 b0750 nadA quinolinate synthetase (NCBI) low > 76
Escherichia coli Nissle 1917 0.52 ECOLIN_RS16170 glycine cleavage system protein GcvH 0.40 ECOLIN_RS03990 quinolinate synthase NadA low > 55
Escherichia coli ECRC100 0.52 OKFHMN_19525 gcvH glycine cleavage system protein GcvH 0.40 OKFHMN_06760 nadA quinolinate synthase NadA low > 79
Escherichia coli ECRC101 0.52 MCAODC_10045 gcvH glycine cleavage system protein GcvH 0.40 MCAODC_25980 nadA quinolinate synthase NadA 0.26 59
Escherichia coli HS(pFamp)R (ATCC 700891) 0.52 OHPLBJKB_00811 Glycine cleavage system H protein 0.40 OHPLBJKB_02963 Quinolinate synthase A low > 74
Escherichia coli ECRC98 0.52 JDDGAC_23165 gcvH glycine cleavage system protein GcvH 0.40 JDDGAC_10415 nadA quinolinate synthase NadA low > 87
Escherichia coli ECRC102 0.52 NIAGMN_17290 gcvH glycine cleavage system protein GcvH 0.40 NIAGMN_04810 nadA quinolinate synthase NadA low > 80
Escherichia fergusonii Becca 0.52 EFB2_00998 Glycine cleavage system H protein 0.40 EFB2_03356 Quinolinate synthase A low > 86
Shewanella loihica PV-4 0.52 Shew_3063 glycine cleavage system protein H (RefSeq) 0.39 Shew_1928 quinolinate synthetase (RefSeq) — —
Escherichia coli ECRC99 0.52 KEDOAH_08615 gcvH glycine cleavage system protein GcvH 0.40 KEDOAH_21205 nadA quinolinate synthase NadA — —
Shewanella sp. ANA-3 0.52 Shewana3_3500 glycine cleavage system protein H (RefSeq) 0.38 Shewana3_2128 quinolinate synthetase (RefSeq) — —
Enterobacter asburiae PDN3 0.52 EX28DRAFT_2956 glycine cleavage system H protein 0.39 EX28DRAFT_2245 quinolinate synthetase (EC 2.5.1.72) low > 76
Pseudomonas sp. BP01 0.52 JOY50_RS11305 gcvH glycine cleavage system protein GcvH 0.38 JOY50_RS01740 nadA quinolinate synthase NadA low > 84
Shewanella oneidensis MR-1 0.52 SO0780 gcvH glycine cleavage system H protein (NCBI ptt file) 0.39 SO2342 nadA quinolinate synthetase complex, subunit A (NCBI ptt file) low > 76
Pectobacterium carotovorum WPP14 0.52 HER17_RS18000 glycine cleavage system protein GcvH 0.38 HER17_RS14820 quinolinate synthase NadA low > 75
Enterobacter sp. TBS_079 0.52 MPMX20_03763 Glycine cleavage system H protein 0.38 MPMX20_01377 Quinolinate synthase A low > 85
Klebsiella pneumoniae MKP103 0.51 KDGMDA_04375 glycine cleavage system protein GcvH 0.40 KDGMDA_16840 quinolinate synthase NadA low > 95
Pantoea sp. MT58 0.51 IAI47_03770 glycine cleavage system protein GcvH 0.39 IAI47_13635 quinolinate synthase NadA low > 76
Pantoea agglomerans CFBP13505 P0401 0.51 PagCFBP13505_RS15930 glycine cleavage system protein GcvH 0.39 PagCFBP13505_RS03665 quinolinate synthase NadA low > 74
Dickeya dianthicola 67-19 0.51 HGI48_RS03395 glycine cleavage system protein GcvH 0.37 HGI48_RS06595 quinolinate synthase NadA low > 71
Phocaeicola vulgatus CL09T03C04 0.51 HMPREF1058_RS12495 glycine cleavage system protein GcvH 0.51 HMPREF1058_RS11230 quinolinate synthase NadA — —
Pseudomonas putida KT2440 0.51 PP_0989 glycine cleavage system H protein 1 0.38 PP_1231 quinolinate synthase [4Fe-4S] cluster subunit 0.21 20
Phocaeicola dorei CL03T12C01 0.51 ABI39_RS04240 glycine cleavage system protein GcvH 0.53 ABI39_RS05755 quinolinate synthase NadA — —
Parabacteroides merdae CL09T00C40 0.50 HMPREF1078_RS05930 glycine cleavage system protein GcvH 0.51 HMPREF1078_RS06555 quinolinate synthase NadA — —
Dickeya dianthicola ME23 0.50 DZA65_RS03440 glycine cleavage system protein GcvH 0.37 DZA65_RS06945 quinolinate synthase NadA low > 75
Alteromonas macleodii MIT1002 0.50 MIT1002_02972 Glycine cleavage system H protein 0.40 MIT1002_01344 Quinolinate synthase A — —
Castellaniella sp019104865 MT123 0.49 ABCV34_RS08840 glycine cleavage system protein GcvH 0.38 ABCV34_RS03700 quinolinate synthase NadA low > 48
Klebsiella michiganensis M5al 0.49 BWI76_RS23875 glycine cleavage system protein H 0.40 BWI76_RS08580 quinolinate synthetase low > 92
Kangiella aquimarina DSM 16071 0.49 B158DRAFT_0544 glycine cleavage system H protein 0.37 B158DRAFT_2453 quinolinate synthetase (EC 2.5.1.72) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.48 Psyr_0247 glycine cleavage system H protein 0.37 Psyr_1542 quinolinate synthetase low > 86
Pseudomonas syringae pv. syringae B728a 0.48 Psyr_0247 glycine cleavage system H protein 0.37 Psyr_1542 quinolinate synthetase low > 86
Pseudomonas sp. SVBP6 0.48 COO64_RS00955 gcvH glycine cleavage system protein GcvH 0.38 COO64_RS20215 nadA quinolinate synthase NadA low > 93
Acinetobacter radioresistens SK82 0.48 MPMX26_01479 Glycine cleavage system H protein 0.38 MPMX26_02602 Quinolinate synthase A low > 36
Serratia liquefaciens MT49 0.48 IAI46_20855 glycine cleavage system protein GcvH 0.38 IAI46_06380 quinolinate synthase NadA low > 86
Pseudomonas fluorescens FW300-N1B4 0.48 Pf1N1B4_620 Glycine cleavage system H protein 0.37 Pf1N1B4_626 Quinolinate synthetase (EC 2.5.1.72) low > 87
Pseudomonas sp. DMC3 0.47 GFF5168 Glycine cleavage system H protein 0.37 GFF5174 Quinolinate synthase A low > 89
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_03495 glycine cleavage system protein H 0.37 AO353_03525 quinolinate synthase A low > 101
Pseudomonas sp. S08-1 0.47 OH686_11170 glycine cleavage system H protein 0.38 OH686_19190 quinolinate synthetase complex, A subunit low > 80
Rahnella sp. WP5 0.47 EX31_RS21515 glycine cleavage system protein GcvH 0.39 EX31_RS23525 quinolinate synthase NadA low > 89
Dechlorosoma suillum PS 0.47 Dsui_2736 glycine cleavage system H protein 0.23 Dsui_1043 quinolinate synthetase complex, A subunit — —
Pseudomonas segetis P6 0.47 MPMX49_04480 Glycine cleavage system H protein 0.38 MPMX49_01696 Quinolinate synthase A — —
Pseudomonas simiae WCS417 0.47 PS417_27250 glycine cleavage system protein H 0.37 PS417_22385 quinolinate synthase A low > 88
Cupriavidus basilensis FW507-4G11 0.47 RR42_RS20065 glycine cleavage system protein H 0.39 RR42_RS17020 quinolinate synthetase low > 128
Acinetobacter baumannii LAC-4 0.47 RR41_RS11930 glycine cleavage system protein GcvH 0.38 RR41_RS15700 quinolinate synthase NadA — —
Pseudomonas fluorescens GW456-L13 0.47 PfGW456L13_1869 glycine cleavage system H protein (EC 1.4.1.27) (from data) 0.37 PfGW456L13_1863 Quinolinate synthetase (EC 2.5.1.72) low > 87
Paraburkholderia graminis OAS925 0.47 ABIE53_000237 glycine cleavage system H protein 0.38 ABIE53_003294 quinolinate synthase low > 113
Pseudomonas stutzeri RCH2 0.46 Psest_0182 glycine cleavage system H protein 0.39 Psest_1509 quinolinate synthetase complex, A subunit low > 67
Paraburkholderia sabiae LMG 24235 0.46 QEN71_RS29210 glycine cleavage system protein GcvH 0.38 QEN71_RS03060 quinolinate synthase NadA low > 153
Pseudomonas fluorescens SBW25 0.46 PFLU_RS23995 glycine cleavage system protein GcvH 0.37 PFLU_RS24025 quinolinate synthase NadA low > 109
Pseudomonas fluorescens FW300-N2E2 0.46 Pf6N2E2_5559 Glycine cleavage system H protein 0.37 Pf6N2E2_5553 Quinolinate synthetase (EC 2.5.1.72) low > 103
Desulfovibrio vulgaris Miyazaki F 0.46 DvMF_0225 glycine cleavage system protein H (RefSeq) 0.22 DvMF_0525 quinolinate synthetase (RefSeq) — —
Pseudomonas fluorescens SBW25-INTG 0.46 PFLU_RS23995 glycine cleavage system protein GcvH 0.37 PFLU_RS24025 quinolinate synthase NadA low > 109
Rhodanobacter sp000427505 FW510-R12 0.46 LRK53_RS04500 glycine cleavage system protein GcvH 0.33 LRK53_RS14710 quinolinate synthase NadA low > 59
Bacteroides stercoris CC31F 0.46 HMPREF1181_RS00935 glycine cleavage system protein GcvH 0.50 HMPREF1181_RS01920 quinolinate synthase NadA — —
Pseudomonas sp. RS175 0.46 PFR28_03382 Glycine cleavage system H protein 0.37 PFR28_03388 Quinolinate synthase A low > 88
Pseudomonas fluorescens FW300-N2C3 0.46 AO356_13040 glycine cleavage system protein H 0.37 AO356_18145 quinolinate synthase A low > 104
Ralstonia solanacearum GMI1000 0.46 RS_RS16505 glycine cleavage system protein H 0.41 RS_RS12295 quinolinate synthase 0.50 18
Pseudomonas lactucae CFBP13502 0.46 GEMAOFIL_04607 Glycine cleavage system H protein 0.37 GEMAOFIL_04613 Quinolinate synthase A low > 93
Pseudomonas aeruginosa PA14 0.46 IKLFDK_27400 glycine cleavage system protein GcvH 0.38 IKLFDK_04555 quinolinate synthase NadA low > 100
Rhodanobacter sp. FW510-T8 0.45 OKGIIK_01310 gcvH glycine cleavage system protein GcvH 0.32 OKGIIK_00930 nadA quinolinate synthase NadA low > 53
Pedobacter sp. GW460-11-11-14-LB5 0.45 CA265_RS18980 glycine cleavage system protein H 0.56 CA265_RS21180 quinolinate synthase — —
Ralstonia solanacearum PSI07 0.45 RPSI07_RS08580 glycine cleavage system protein H 0.40 RPSI07_RS12650 quinolinate synthase NadA low > 81
Burkholderia phytofirmans PsJN 0.45 BPHYT_RS19325 glycine cleavage system H protein 0.37 BPHYT_RS15650 quinolinate synthetase low > 109
Synechocystis sp000284455 PCC 6803 0.45 SGL_RS07170 glycine cleavage system protein GcvH 0.56 SGL_RS17340 quinolinate synthase NadA 0.72 10
Dickeya dadantii 3937 0.45 DDA3937_RS03250 glycine cleavage system protein GcvH 0.37 DDA3937_RS06545 quinolinate synthase NadA low > 74
Desulfovibrio vulgaris Hildenborough JW710 0.45 DVU1426 gcvH glycine cleavage system H protein (TIGR) 0.20 DVU1808 nadA quinolinate synthetase complex, subunit A (TIGR) — —
Ralstonia solanacearum IBSBF1503 0.44 RALBFv3_RS08655 glycine cleavage system protein H 0.40 RALBFv3_RS04735 quinolinate synthase NadA low > 76
Ralstonia solanacearum UW163 0.44 UW163_RS04955 glycine cleavage system protein H 0.40 UW163_RS08935 quinolinate synthase NadA — —
Synechococcus elongatus PCC 7942 0.44 Synpcc7942_2046 gcsH glycine cleavage system protein H 0.56 Synpcc7942_1448 nadA quinolinate synthetase 0.47 14
Vibrio cholerae E7946 ATCC 55056 0.44 CSW01_15335 glycine cleavage system protein H 0.40 CSW01_09180 quinolinate synthase low > 62
Mucilaginibacter yixingensis YX-36 DSM 26809 0.44 ABZR88_RS00300 glycine cleavage system protein GcvH 0.56 ABZR88_RS20650 quinolinate synthase NadA — —
Mycobacterium tuberculosis H37Rv 0.42 Rv1826 Probable glycine cleavage system H protein GcvH 0.34 Rv1594 Probable quinolinate synthetase NadA — —
Ralstonia sp. UNC404CL21Col 0.42 ABZR87_RS03930 glycine cleavage system protein GcvH 0.40 ABZR87_RS00355 quinolinate synthase NadA low > 80
Rhodanobacter denitrificans FW104-10B01 0.40 LRK54_RS05505 glycine cleavage system protein GcvH 0.34 LRK54_RS13900 quinolinate synthase NadA low > 59
Rhodanobacter denitrificans MT42 0.40 LRK55_RS05275 glycine cleavage system protein GcvH 0.34 LRK55_RS13615 quinolinate synthase NadA low > 63
Herbaspirillum seropedicae SmR1 0.39 HSERO_RS07915 glycine cleavage system protein H 0.37 HSERO_RS11065 quinolinate synthetase low > 78
Methylophilus sp. DMC18 0.36 GFF2310 Glycine cleavage system H protein 0.23 GFF2202 Quinolinate synthase A — —

Not shown: 13 genomes with orthologs for GFF1922 only; 3 genomes with orthologs for GFF246 only