Conservation of cofitness between DZA65_RS10050 and DZA65_RS19200 in Dickeya dianthicola ME23

88 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Dickeya dianthicola ME23 1.0 DZA65_RS10050 histidinol-phosphate transaminase 1.0 DZA65_RS19200 2-isopropylmalate synthase 0.74 16
Dickeya dianthicola 67-19 1.00 HGI48_RS09740 histidinol-phosphate transaminase 1.00 HGI48_RS18055 2-isopropylmalate synthase 0.77 27
Dickeya dadantii 3937 0.95 DDA3937_RS09730 histidinol-phosphate transaminase 0.99 DDA3937_RS18115 2-isopropylmalate synthase 0.77 60
Pectobacterium carotovorum WPP14 0.81 HER17_RS12235 histidinol-phosphate transaminase 0.90 HER17_RS03085 2-isopropylmalate synthase 0.98 7
Serratia liquefaciens MT49 0.79 IAI46_08205 histidinol-phosphate transaminase 0.84 IAI46_03355 2-isopropylmalate synthase low > 86
Rahnella sp. WP5 0.75 EX31_RS11445 histidinol-phosphate transaminase 0.81 EX31_RS03680 2-isopropylmalate synthase 0.96 28
Enterobacter sp. TBS_079 0.74 MPMX20_03003 Histidinol-phosphate aminotransferase 0.85 MPMX20_00769 2-isopropylmalate synthase 0.92 28
Escherichia coli ECOR27 0.74 NOLOHH_15825 hisC histidinol-phosphate transaminase 0.85 NOLOHH_03060 2-isopropylmalate synthase 0.95 7
Escherichia coli ECRC100 0.73 OKFHMN_24510 hisC histidinol-phosphate transaminase 0.85 OKFHMN_10715 2-isopropylmalate synthase 0.94 28
Escherichia coli BW25113 0.73 b2021 hisC histidinol-phosphate aminotransferase (NCBI) 0.85 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.95 7
Escherichia coli ECRC99 0.73 KEDOAH_03640 hisC histidinol-phosphate transaminase 0.85 KEDOAH_17440 2-isopropylmalate synthase — —
Escherichia coli ECRC98 0.73 JDDGAC_28620 hisC histidinol-phosphate transaminase 0.85 JDDGAC_14310 2-isopropylmalate synthase 0.89 20
Escherichia coli ECRC102 0.73 NIAGMN_22455 hisC histidinol-phosphate transaminase 0.85 NIAGMN_08565 2-isopropylmalate synthase — —
Escherichia coli ECRC101 0.73 MCAODC_20430 hisC histidinol-phosphate transaminase 0.85 MCAODC_01230 2-isopropylmalate synthase 0.97 4
Escherichia fergusonii Becca 0.73 EFB2_01835 Histidinol-phosphate aminotransferase 0.85 EFB2_03971 2-isopropylmalate synthase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.73 OHPLBJKB_01679 Histidinol-phosphate aminotransferase 0.85 OHPLBJKB_03583 2-isopropylmalate synthase low > 73
Escherichia coli ECOR38 0.73 HEPCGN_03215 hisC histidinol-phosphate transaminase 0.85 HEPCGN_08695 2-isopropylmalate synthase 0.98 5
Escherichia coli BL21 0.73 ECD_01923 histidinol-phosphate aminotransferase 0.85 ECD_00076 2-isopropylmalate synthase 0.91 7
Escherichia coli ECRC62 0.73 BNILDI_14735 hisC histidinol-phosphate transaminase 0.85 BNILDI_08550 2-isopropylmalate synthase 0.97 27
Escherichia coli Nissle 1917 0.73 ECOLIN_RS11950 histidinol-phosphate transaminase 0.85 ECOLIN_RS00400 2-isopropylmalate synthase — —
Enterobacter asburiae PDN3 0.73 EX28DRAFT_0538 histidinol-phosphate aminotransferase 0.85 EX28DRAFT_3670 2-isopropylmalate synthase (EC 2.3.3.13) 0.84 27
Pantoea sp. MT58 0.73 IAI47_07085 histidinol-phosphate transaminase 0.81 IAI47_16000 2-isopropylmalate synthase 0.98 14
Erwinia tracheiphila SCR3 0.72 LU632_RS08940 hisC histidinol-phosphate transaminase 0.83 LU632_RS02880 leuA 2-isopropylmalate synthase low > 74
Klebsiella michiganensis M5al 0.71 BWI76_RS18930 histidinol-phosphate transaminase 0.86 BWI76_RS04680 2-isopropylmalate synthase 0.86 24
Vibrio cholerae E7946 ATCC 55056 0.59 CSW01_05755 histidinol-phosphate transaminase 0.70 CSW01_12595 2-isopropylmalate synthase low > 62
Alteromonas macleodii MIT1002 0.48 MIT1002_02634 Histidinol-phosphate aminotransferase 0.60 MIT1002_00949 2-isopropylmalate synthase 0.93 44
Shewanella sp. ANA-3 0.42 Shewana3_1852 histidinol phosphate aminotransferase (RefSeq) 0.66 Shewana3_3761 2-isopropylmalate synthase (RefSeq) 0.95 12
Shewanella oneidensis MR-1 0.41 SO2072 hisC histidinol-phosphate aminotransferase (NCBI ptt file) 0.65 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.98 8
Shewanella loihica PV-4 0.40 Shew_2199 histidinol-phosphate aminotransferase (RefSeq) 0.66 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.96 10
Rhodanobacter denitrificans FW104-10B01 0.40 LRK54_RS01600 histidinol-phosphate transaminase 0.41 LRK54_RS10345 2-isopropylmalate synthase 0.59 33
Rhodanobacter denitrificans MT42 0.39 LRK55_RS01380 histidinol-phosphate transaminase 0.41 LRK55_RS09985 2-isopropylmalate synthase low > 63
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_04955 hisC histidinol-phosphate transaminase 0.40 OKGIIK_13575 leuA 2-isopropylmalate synthase low > 52
Xanthomonas campestris pv. campestris strain 8004 0.36 Xcc-8004.2947.1 Histidinol-phosphate aminotransferase (EC 2.6.1.9) 0.39 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) 0.82 19
Dyella japonica UNC79MFTsu3.2 0.34 ABZR86_RS06725 histidinol-phosphate transaminase 0.41 ABZR86_RS15970 2-isopropylmalate synthase 0.97 10
Lysobacter sp. OAE881 0.34 ABIE51_RS13320 histidinol-phosphate transaminase 0.41 ABIE51_RS17570 2-isopropylmalate synthase low > 62
Shewanella amazonensis SB2B 0.32 Sama_1943 histidinol-phosphate aminotransferase (RefSeq) 0.67 Sama_0335 2-isopropylmalate synthase (RefSeq) 0.93 40
Parabacteroides merdae CL09T00C40 0.31 HMPREF1078_RS02445 histidinol-phosphate transaminase 0.44 HMPREF1078_RS16665 2-isopropylmalate synthase 0.93 46
Bacteroides stercoris CC31F 0.30 HMPREF1181_RS04855 histidinol-phosphate transaminase 0.43 HMPREF1181_RS14150 2-isopropylmalate synthase 0.93 20
Bacteroides ovatus ATCC 8483 0.29 BACOVA_01233 histidinol-phosphate transaminase 0.43 BACOVA_04604 2-isopropylmalate synthase 0.91 41
Phocaeicola vulgatus CL09T03C04 0.28 HMPREF1058_RS15880 histidinol-phosphate transaminase 0.45 HMPREF1058_RS14545 2-isopropylmalate synthase 0.91 18
Bacteroides thetaiotaomicron VPI-5482 0.28 BT0202 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) 0.43 BT1861 2-isopropylmalate synthase (EC 2.3.3.13) (from data) 0.95 3
Phocaeicola dorei CL03T12C01 0.28 ABI39_RS11840 histidinol-phosphate transaminase 0.44 ABI39_RS10195 2-isopropylmalate synthase 0.70 39
Variovorax sp. SCN45 0.20 GFF5348 Histidinol-phosphate aminotransferase (EC 2.6.1.9) 0.41 GFF1165 2-isopropylmalate synthase (EC 2.3.3.13) low > 127
Cupriavidus basilensis FW507-4G11 0.20 RR42_RS18910 histidinol-phosphate aminotransferase 0.41 RR42_RS05465 2-isopropylmalate synthase — —
Methanococcus maripaludis S2 0.20 MMP_RS06260 histidinol-phosphate transaminase 0.30 MMP_RS05500 2-isopropylmalate synthase — —
Methanococcus maripaludis JJ 0.20 MMJJ_RS08090 histidinol-phosphate transaminase 0.30 MMJJ_RS08870 2-isopropylmalate synthase — —
Paraburkholderia sabiae LMG 24235 0.19 QEN71_RS27860 histidinol-phosphate transaminase 0.42 QEN71_RS24195 2-isopropylmalate synthase low > 153
Variovorax sp. OAS795 0.19 ABID97_RS23145 histidinol-phosphate transaminase 0.41 ABID97_RS14910 2-isopropylmalate synthase low > 91
Hydrogenophaga sp. GW460-11-11-14-LB1 0.19 GFF1313 Histidinol-phosphate aminotransferase (EC 2.6.1.9) 0.42 GFF4281 2-isopropylmalate synthase (EC 2.3.3.13) low > 90
Acidovorax sp. GW101-3H11 0.19 Ac3H11_4729 histidinol-phosphate transaminase (EC 2.6.1.9) (from data) 0.41 Ac3H11_530 2-isopropylmalate synthase (EC 2.3.3.13) — —
Desulfovibrio vulgaris Hildenborough JW710 0.19 DVU1029 hisC histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) 0.43 DVU2981 leuA 2-isopropylmalate synthase (TIGR) 0.81 23
Ralstonia solanacearum GMI1000 0.19 RS_RS14785 histidinol-phosphate aminotransferase 1 0.41 RS_RS10395 2-isopropylmalate synthase — —
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS14905 Aromatic-amino-acid transaminase (EC 2.6.1.57) (from data) 0.43 BPHYT_RS06570 2-isopropylmalate synthase low > 109
Ralstonia solanacearum IBSBF1503 0.19 RALBFv3_RS06840 histidinol-phosphate transaminase 0.41 RALBFv3_RS03025 2-isopropylmalate synthase — —
Ralstonia solanacearum UW163 0.19 UW163_RS06775 histidinol-phosphate transaminase 0.41 UW163_RS10700 2-isopropylmalate synthase — —
Paraburkholderia graminis OAS925 0.19 ABIE53_003700 histidinol-phosphate aminotransferase 0.43 ABIE53_001580 2-isopropylmalate synthase low > 113
Ralstonia solanacearum PSI07 0.19 RPSI07_RS10395 histidinol-phosphate transaminase 0.41 RPSI07_RS14285 2-isopropylmalate synthase — —
Pseudomonas sp. S08-1 0.18 OH686_20875 histidinol-phosphate transaminase 0.12 OH686_17570 2-isopropylmalate synthase low > 80
Paraburkholderia bryophila 376MFSha3.1 0.18 H281DRAFT_05654 histidinol phosphate aminotransferase apoenzyme 0.43 H281DRAFT_04556 2-isopropylmalate synthase low > 103
Ralstonia sp. UNC404CL21Col 0.18 ABZR87_RS02495 histidinol-phosphate transaminase 0.41 ABZR87_RS14930 2-isopropylmalate synthase low > 80
Pseudomonas fluorescens FW300-N2C3 0.18 AO356_03460 aspartate aminotransferase 0.12 AO356_06550 2-isopropylmalate synthase low > 104
Desulfovibrio vulgaris Miyazaki F 0.18 DvMF_0908 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) 0.43 DvMF_1791 2-isopropylmalate synthase (RefSeq) 0.93 21
Pseudomonas stutzeri RCH2 0.18 Psest_1985 histidinol-phosphate aminotransferase 0.47 Psest_1056 2-isopropylmalate synthase, bacterial type low > 67
Pseudomonas simiae WCS417 0.18 PS417_08130 aspartate aminotransferase 0.11 PS417_23110 2-isopropylmalate synthase low > 88
Pseudomonas fluorescens FW300-N2E2 0.18 Pf6N2E2_2519 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) 0.12 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) low > 103
Castellaniella sp019104865 MT123 0.17 ABCV34_RS07105 histidinol-phosphate transaminase 0.11 ABCV34_RS12420 2-isopropylmalate synthase low > 48
Pseudomonas fluorescens SBW25-INTG 0.17 PFLU_RS08100 histidinol-phosphate transaminase 0.11 PFLU_RS24765 2-isopropylmalate synthase low > 109
Pseudomonas fluorescens SBW25 0.17 PFLU_RS08100 histidinol-phosphate transaminase 0.11 PFLU_RS24765 2-isopropylmalate synthase low > 109
Pseudomonas fluorescens GW456-L13 0.17 PfGW456L13_2177 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) 0.11 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) 0.43 34
Sphingomonas koreensis DSMZ 15582 0.17 Ga0059261_2299 histidinol-phosphate aminotransferase 0.12 Ga0059261_4031 2-isopropylmalate synthase, yeast type 0.99 9
Pseudomonas fluorescens FW300-N1B4 0.17 Pf1N1B4_349 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) 0.11 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) 0.47 50
Pseudomonas sp. RS175 0.17 PFR28_00908 Histidinol-phosphate aminotransferase 0.11 PFR28_00305 2-isopropylmalate synthase low > 88
Magnetospirillum magneticum AMB-1 0.17 AMB_RS20110 histidinol-phosphate aminotransferase 0.44 AMB_RS17765 2-isopropylmalate synthase — —
Marinobacter adhaerens HP15 0.17 HP15_2427 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) 0.45 HP15_538 2-isopropylmalate synthase low > 73
Phaeobacter inhibens DSM 17395 0.16 PGA1_c25240 histidinol-phosphate aminotransferase [EC:2.6.1.9] (from data) 0.40 PGA1_c26470 2-isopropylmalate synthase LeuA — —
Bifidobacterium breve UCC2003 0.16 BBR_RS17050 histidinol-phosphate transaminase 0.10 BBR_RS11170 2-isopropylmalate synthase low > 34
Synechococcus elongatus PCC 7942 0.16 Synpcc7942_1030 hisC histidinol-phosphate aminotransferase 0.42 Synpcc7942_1410 leuA 2-isopropylmalate synthase — —
Dechlorosoma suillum PS 0.15 Dsui_1414 histidinol-phosphate aminotransferase 0.45 Dsui_3519 2-isopropylmalate synthase, bacterial type — —
Dinoroseobacter shibae DFL-12 0.15 Dshi_2946 histidinol-phosphate aminotransferase (RefSeq) 0.39 Dshi_0596 2-isopropylmalate synthase (RefSeq) — —
Acinetobacter radioresistens SK82 0.15 MPMX26_02586 Histidinol-phosphate aminotransferase 0.12 MPMX26_00404 2-isopropylmalate synthase low > 36
Caulobacter crescentus NA1000 0.15 CCNA_02617 histidinol-phosphate aminotransferase 0.41 CCNA_01610 2-isopropylmalate synthase low > 66
Caulobacter crescentus NA1000 Δfur 0.15 CCNA_02617 histidinol-phosphate aminotransferase 0.41 CCNA_01610 2-isopropylmalate synthase low > 67
Pseudomonas syringae pv. syringae B728a ΔmexB 0.15 Psyr_4132 histidinol phosphate aminotransferase apoenzyme 0.11 Psyr_1257 2-isopropylmalate synthase 0.87 12
Pseudomonas syringae pv. syringae B728a 0.15 Psyr_4132 histidinol phosphate aminotransferase apoenzyme 0.11 Psyr_1257 2-isopropylmalate synthase 0.90 12
Rhodopseudomonas palustris CGA009 0.14 TX73_023035 histidinol-phosphate transaminase 0.41 TX73_010545 2-isopropylmalate synthase — —
Sinorhizobium meliloti 1021 0.14 SMc00710 histidinol-phosphate aminotransferase 0.16 SMc02546 alpha-isopropylmalate/homocitrate synthase family transferase low > 103
Pseudomonas putida KT2440 0.13 PP_0967 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) 0.11 PP_1025 2-isopropylmalate synthase 0.86 22
Rhizobium sp. OAE497 0.13 ABIE40_RS17595 histidinol-phosphate transaminase 0.16 ABIE40_RS06220 citramalate synthase low > 107
Agrobacterium fabrum C58 0.12 Atu3612 histidinol-phosphate aminotransferase 0.10 Atu2264 2-isopropylmalate synthase — —

Not shown: 14 genomes with orthologs for DZA65_RS10050 only; 1 genomes with orthologs for DZA65_RS19200 only