Conservation of cofitness between CSW01_02450 and CSW01_12680 in Vibrio cholerae E7946 ATCC 55056

98 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02450 pyrroline-5-carboxylate reductase 1.0 CSW01_12680 cytosol aminopeptidase 0.87 3
Pectobacterium carotovorum WPP14 0.69 HER17_RS03805 pyrroline-5-carboxylate reductase 0.81 HER17_RS19450 leucyl aminopeptidase — —
Serratia liquefaciens MT49 0.69 IAI46_21415 pyrroline-5-carboxylate reductase 0.83 IAI46_02360 leucyl aminopeptidase low > 86
Dickeya dadantii 3937 0.68 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.83 DDA3937_RS01995 leucyl aminopeptidase low > 74
Dickeya dianthicola 67-19 0.68 HGI48_RS17350 pyrroline-5-carboxylate reductase 0.83 HGI48_RS01955 leucyl aminopeptidase — —
Dickeya dianthicola ME23 0.67 DZA65_RS18440 pyrroline-5-carboxylate reductase 0.83 DZA65_RS02060 leucyl aminopeptidase — —
Rahnella sp. WP5 0.65 EX31_RS02690 pyrroline-5-carboxylate reductase 0.83 EX31_RS04385 leucyl aminopeptidase low > 89
Alteromonas macleodii MIT1002 0.60 MIT1002_03062 Pyrroline-5-carboxylate reductase 0.79 MIT1002_03197 Cytosol aminopeptidase low > 70
Shewanella oneidensis MR-1 0.57 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) 0.81 SO1368 pepA-2 cytosol aminopeptidase (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.56 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) 0.81 Shewana3_3006 leucyl aminopeptidase (RefSeq) low > 73
Shewanella loihica PV-4 0.52 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.81 Shew_0939 leucyl aminopeptidase (RefSeq) low > 60
Shewanella amazonensis SB2B 0.50 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) 0.81 Sama_0795 leucyl aminopeptidase (RefSeq) low > 62
Kangiella aquimarina DSM 16071 0.42 B158DRAFT_0197 pyrroline-5-carboxylate reductase 0.60 B158DRAFT_1167 Leucyl aminopeptidase low > 40
Marinobacter adhaerens HP15 0.38 HP15_287 pyrroline-5-carboxylate reductase 0.46 HP15_1315 leucyl aminopeptidase — —
Acinetobacter baumannii LAC-4 0.38 RR41_RS15925 pyrroline-5-carboxylate reductase 0.38 RR41_RS17825 leucyl aminopeptidase low > 55
Pseudomonas sp. BP01 0.37 JOY50_RS20905 proC pyrroline-5-carboxylate reductase 0.52 JOY50_RS11265 leucyl aminopeptidase low > 84
Pseudomonas lactucae CFBP13502 0.37 GEMAOFIL_05483 Pyrroline-5-carboxylate reductase 0.54 GEMAOFIL_01239 Cytosol aminopeptidase — —
Paraburkholderia graminis OAS925 0.37 ABIE53_000840 pyrroline-5-carboxylate reductase 0.51 ABIE53_001235 leucyl aminopeptidase low > 113
Pseudomonas fluorescens SBW25 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.54 PFLU_RS05235 leucyl aminopeptidase — —
Pseudomonas fluorescens SBW25-INTG 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.54 PFLU_RS05235 leucyl aminopeptidase — —
Pseudomonas putida KT2440 0.37 PP_5095 pyrroline-5-carboxylate reductase 0.52 PP_0980 Probable cytosol aminopeptidase low > 96
Lysobacter sp. OAE881 0.37 ABIE51_RS16065 pyrroline-5-carboxylate reductase 0.46 ABIE51_RS04475 leucyl aminopeptidase low > 62
Pseudomonas sp. SVBP6 0.36 COO64_RS12995 proC pyrroline-5-carboxylate reductase 0.51 COO64_RS04415 leucyl aminopeptidase — —
Pseudomonas simiae WCS417 0.36 PS417_26730 pyrroline-5-carboxylate reductase 0.54 PS417_05165 cytosol aminopeptidase low > 88
Dechlorosoma suillum PS 0.36 Dsui_0602 pyrroline-5-carboxylate reductase 0.59 Dsui_3536 leucyl aminopeptidase — —
Paraburkholderia sabiae LMG 24235 0.36 QEN71_RS26600 pyrroline-5-carboxylate reductase 0.51 QEN71_RS25205 leucyl aminopeptidase low > 153
Pseudomonas syringae pv. syringae B728a ΔmexB 0.36 Psyr_0476 pyrroline-5-carboxylate reductase 0.54 Psyr_1091 aminopeptidase A, Metallo peptidase, MEROPS family M17 low > 86
Pseudomonas syringae pv. syringae B728a 0.36 Psyr_0476 pyrroline-5-carboxylate reductase 0.54 Psyr_1091 aminopeptidase A, Metallo peptidase, MEROPS family M17 — —
Pseudomonas segetis P6 0.36 MPMX49_00610 Pyrroline-5-carboxylate reductase 0.53 MPMX49_03516 Cytosol aminopeptidase — —
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_13420 pyrroline-5-carboxylate reductase 0.54 AO356_17470 aminopeptidase — —
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_08165 pyrroline-5-carboxylate reductase 0.54 AO353_04535 aminopeptidase low > 101
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.54 PfGW456L13_4846 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 87
Paraburkholderia bryophila 376MFSha3.1 0.35 H281DRAFT_04679 pyrroline-5-carboxylate reductase 0.51 H281DRAFT_00123 aminopeptidase A. Metallo peptidase. MEROPS family M17 low > 103
Pseudomonas fluorescens FW300-N2E2 0.35 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.54 Pf6N2E2_5420 Cytosol aminopeptidase PepA (EC 3.4.11.1) — —
Pseudomonas aeruginosa PA14 0.35 IKLFDK_23455 pyrroline-5-carboxylate reductase 0.51 IKLFDK_19730 leucyl aminopeptidase low > 100
Burkholderia phytofirmans PsJN 0.35 BPHYT_RS03490 pyrroline-5-carboxylate reductase 0.51 BPHYT_RS04795 cytosol aminopeptidase — —
Pseudomonas sp. RS175 0.35 PFR28_04243 Pyrroline-5-carboxylate reductase 0.53 PFR28_03528 Cytosol aminopeptidase — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS01230 pyrroline-5-carboxylate reductase 0.50 ABZR87_RS00150 leucyl aminopeptidase — —
Pseudomonas sp. S08-1 0.35 OH686_10980 pyrroline-5-carboxylate reductase 0.52 OH686_07810 Cytosol aminopeptidase PepA low > 80
Pseudomonas fluorescens FW300-N1B4 0.35 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.54 Pf1N1B4_898 Cytosol aminopeptidase PepA (EC 3.4.11.1) — —
Pseudomonas stutzeri RCH2 0.34 Psest_0283 pyrroline-5-carboxylate reductase 0.51 Psest_1235 Leucyl aminopeptidase — —
Pseudomonas sp. DMC3 0.34 GFF210 Pyrroline-5-carboxylate reductase 0.54 GFF1952 Cytosol aminopeptidase — —
Ralstonia solanacearum GMI1000 0.33 RS_RS13440 pyrroline-5-carboxylate reductase 0.47 RS_RS12120 cytosol aminopeptidase — —
Ralstonia solanacearum UW163 0.32 UW163_RS08045 pyrroline-5-carboxylate reductase 0.48 UW163_RS09120 leucyl aminopeptidase — —
Ralstonia solanacearum IBSBF1503 0.32 RALBFv3_RS05580 pyrroline-5-carboxylate reductase 0.48 RALBFv3_RS04550 leucyl aminopeptidase low > 76
Dyella japonica UNC79MFTsu3.2 0.32 ABZR86_RS10425 pyrroline-5-carboxylate reductase 0.42 ABZR86_RS19105 leucyl aminopeptidase low > 74
Ralstonia solanacearum PSI07 0.32 RPSI07_RS11720 pyrroline-5-carboxylate reductase 0.49 RPSI07_RS12825 leucyl aminopeptidase low > 81
Variovorax sp. OAS795 0.32 ABID97_RS01555 pyrroline-5-carboxylate reductase 0.37 ABID97_RS16580 leucyl aminopeptidase — —
Acidovorax sp. GW101-3H11 0.32 Ac3H11_788 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.36 Ac3H11_2399 Cytosol aminopeptidase PepA (EC 3.4.11.1) — —
Castellaniella sp019104865 MT123 0.32 ABCV34_RS03610 pyrroline-5-carboxylate reductase 0.43 ABCV34_RS08295 leucyl aminopeptidase — —
Methylophilus sp. DMC18 0.31 GFF863 Pyrroline-5-carboxylate reductase 0.49 GFF1514 Cytosol aminopeptidase — —
Variovorax sp. SCN45 0.31 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.36 GFF240 Cytosol aminopeptidase PepA (EC 3.4.11.1) — —
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.1710.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.44 Xcc-8004.4446.1 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 74
Rhodanobacter sp000427505 FW510-R12 0.30 LRK53_RS05680 pyrroline-5-carboxylate reductase 0.45 LRK53_RS16125 leucyl aminopeptidase low > 59
Cupriavidus basilensis FW507-4G11 0.30 RR42_RS17360 pyrroline-5-carboxylate reductase 0.48 RR42_RS16225 cytosol aminopeptidase — —
Rhodanobacter sp. FW510-T8 0.30 OKGIIK_11135 proC pyrroline-5-carboxylate reductase 0.43 OKGIIK_11560 pepB leucyl aminopeptidase low > 52
Rhodanobacter denitrificans FW104-10B01 0.29 LRK54_RS04260 pyrroline-5-carboxylate reductase 0.44 LRK54_RS12375 leucyl aminopeptidase low > 59
Rhodanobacter denitrificans MT42 0.29 LRK55_RS04030 pyrroline-5-carboxylate reductase 0.44 LRK55_RS12110 leucyl aminopeptidase — —
Herbaspirillum seropedicae SmR1 0.29 HSERO_RS18990 pyrroline-5-carboxylate reductase 0.46 HSERO_RS15600 cytosol aminopeptidase low > 78
Hydrogenophaga sp. GW460-11-11-14-LB1 0.28 GFF2806 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.36 GFF4309 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 90
Magnetospirillum magneticum AMB-1 0.28 AMB_RS02820 pyrroline-5-carboxylate reductase 0.32 AMB_RS18600 leucyl aminopeptidase — —
Escherichia fergusonii Becca 0.27 EFB2_03670 Pyrroline-5-carboxylate reductase 0.82 EFB2_04275 Cytosol aminopeptidase low > 86
Enterobacter asburiae PDN3 0.27 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.82 EX28DRAFT_3267 Leucyl aminopeptidase low > 76
Enterobacter sp. TBS_079 0.27 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.82 MPMX20_04118 Cytosol aminopeptidase low > 85
Klebsiella pneumoniae MKP103 0.27 KDGMDA_14250 pyrroline-5-carboxylate reductase 0.81 KDGMDA_11530 leucyl aminopeptidase low > 95
Klebsiella michiganensis M5al 0.27 BWI76_RS06170 pyrroline-5-carboxylate reductase 0.81 BWI76_RS03040 leucyl aminopeptidase — —
Escherichia coli Nissle 1917 0.27 ECOLIN_RS02345 pyrroline-5-carboxylate reductase 0.82 ECOLIN_RS24695 leucyl aminopeptidase low > 55
Escherichia coli BW25113 0.27 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.82 b4260 pepA leucyl aminopeptidase (NCBI) low > 76
Escherichia coli BL21 0.27 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding 0.82 ECD_04126 multifunctional aminopeptidase A: a cyteinylglycinase, transcription regulator and site-specific recombination factor low > 61
Escherichia coli ECOR38 0.27 HEPCGN_07250 proC pyrroline-5-carboxylate reductase 0.82 HEPCGN_09980 pepA leucyl aminopeptidase low > 88
Escherichia coli ECOR27 0.27 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 0.82 NOLOHH_04055 pepA leucyl aminopeptidase low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.27 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase 0.82 OHPLBJKB_03776 Cytosol aminopeptidase low > 74
Escherichia coli ECRC62 0.27 BNILDI_22950 proC pyrroline-5-carboxylate reductase 0.82 BNILDI_07455 pepA leucyl aminopeptidase low > 75
Escherichia coli ECRC100 0.27 OKFHMN_08610 proC pyrroline-5-carboxylate reductase 0.82 OKFHMN_11790 pepA leucyl aminopeptidase low > 79
Escherichia coli ECRC99 0.27 KEDOAH_19355 proC pyrroline-5-carboxylate reductase 0.82 KEDOAH_16360 pepA leucyl aminopeptidase — —
Escherichia coli ECRC98 0.27 JDDGAC_12265 proC pyrroline-5-carboxylate reductase 0.82 JDDGAC_15430 pepA leucyl aminopeptidase low > 87
Escherichia coli ECRC102 0.27 NIAGMN_06665 proC pyrroline-5-carboxylate reductase 0.82 NIAGMN_09640 pepA leucyl aminopeptidase low > 80
Escherichia coli ECRC101 0.27 MCAODC_27835 proC pyrroline-5-carboxylate reductase 0.82 MCAODC_02295 pepA leucyl aminopeptidase low > 88
Erwinia amylovora T8 0.26 OLJFJH_18285 pyrroline-5-carboxylate reductase 0.84 OLJFJH_07380 leucyl aminopeptidase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.26 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.82 GFF949 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 78
Pantoea sp. MT58 0.26 IAI47_14945 pyrroline-5-carboxylate reductase 0.83 IAI47_16795 leucyl aminopeptidase low > 76
Pantoea agglomerans CFBP13505 P0401 0.26 PagCFBP13505_RS10205 pyrroline-5-carboxylate reductase 0.83 PagCFBP13505_RS08910 leucyl aminopeptidase low > 74
Azospirillum sp. SherDot2 0.25 MPMX19_01399 Pyrroline-5-carboxylate reductase 0.27 MPMX19_01593 Cytosol aminopeptidase — —
Synechocystis sp000284455 PCC 6803 0.25 SGL_RS17305 pyrroline-5-carboxylate reductase 0.24 SGL_RS09430 leucyl aminopeptidase low > 52
Desulfovibrio vulgaris Hildenborough JW710 0.24 DVU2332 proC pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.28 DVU0415 pepA cytosol aminopeptidase (TIGR) low > 55
Sinorhizobium meliloti 1021 0.24 SMc02677 pyrroline-5-carboxylate reductase 0.28 SMc00585 leucyl aminopeptidase low > 103
Rhodopseudomonas palustris CGA009 0.24 TX73_022630 pyrroline-5-carboxylate reductase 0.25 TX73_015830 leucyl aminopeptidase — —
Erwinia tracheiphila HP pepo 2.2 0.23 IJEDHG_26195 proC pyrroline-5-carboxylate reductase 0.84 IJEDHG_14170 pepA leucyl aminopeptidase — —
Erwinia tracheiphila SCR3 0.23 LU632_RS18995 proC pyrroline-5-carboxylate reductase 0.84 LU632_RS20855 pepA leucyl aminopeptidase low > 74
Rhodospirillum rubrum S1H 0.23 Rru_A3281 Delta 1-pyrroline-5-carboxylate reductase (NCBI) 0.31 Rru_A0454 Leucyl aminopeptidase (NCBI) — —
Azospirillum brasilense Sp245 0.23 AZOBR_RS06245 pyrroline-5-carboxylate reductase 0.29 AZOBR_RS16385 aminopeptidase A — —
Xanthobacter sp. DMC5 0.22 GFF1925 Pyrroline-5-carboxylate reductase 0.28 GFF142 Cytosol aminopeptidase — —
Desulfovibrio vulgaris Miyazaki F 0.21 DvMF_3161 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.28 DvMF_1538 Leucyl aminopeptidase (RefSeq) low > 51
Dinoroseobacter shibae DFL-12 0.20 Dshi_2645 pyrroline-5-carboxylate reductase (RefSeq) 0.25 Dshi_1191 Leucyl aminopeptidase (RefSeq) — —
Caulobacter crescentus NA1000 Δfur 0.20 CCNA_00528 pyrroline-5-carboxylate reductase 0.31 CCNA_01763 multifunctional aminopeptidase low > 67
Caulobacter crescentus NA1000 0.20 CCNA_00528 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.31 CCNA_01763 multifunctional aminopeptidase low > 66
Bosea sp. OAE506 0.19 ABIE41_RS11365 pyrroline-5-carboxylate reductase 0.27 ABIE41_RS17710 leucyl aminopeptidase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.16 A4249_RS09840 pyrroline-5-carboxylate reductase dimerization domain-containing protein 0.30 A4249_RS06730 leucyl aminopeptidase — —
Mycobacterium tuberculosis H37Rv 0.16 Rv0500 Probable pyrroline-5-carboxylate reductase ProC (P5CR) (P5C reductase) 0.22 Rv2213 Probable aminopeptidase PepB — —

Not shown: 19 genomes with orthologs for CSW01_02450 only; 1 genomes with orthologs for CSW01_12680 only