| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_03510 | | NADP(H)-dependent aldo-keto reductase | 1.0 | CSW01_10170 | | MarC family protein | 0.71 | 3 |
| Serratia liquefaciens MT49 | 0.66 | IAI46_20475 | | NADP(H)-dependent aldo-keto reductase | 0.63 | IAI46_14215 | | YchE family NAAT transporter | low | > 87 |
| Pantoea sp. MT58 | 0.65 | IAI47_03895 | | NADP(H)-dependent aldo-keto reductase | 0.64 | IAI47_09060 | | YchE family NAAT transporter | low | > 76 |
| Shewanella loihica PV-4 | 0.65 | Shew_0736 | | aldo/keto reductase (RefSeq) | 0.55 | Shew_1911 | | hypothetical protein (RefSeq) | — | — |
| Rahnella sp. WP5 | 0.65 | EX31_RS13220 | | NADP(H)-dependent aldo-keto reductase | 0.64 | EX31_RS10070 | | YchE family NAAT transporter | low | > 89 |
| Pantoea agglomerans CFBP13505 P0401 | 0.65 | PagCFBP13505_RS17075 | | NADP(H)-dependent aldo-keto reductase | 0.64 | PagCFBP13505_RS02900 | | YchE family NAAT transporter | low | > 74 |
| Dickeya dianthicola 67-19 | 0.65 | HGI48_RS04935 | | NADP(H)-dependent aldo-keto reductase | 0.64 | HGI48_RS10375 | | YchE family NAAT transporter | low | > 71 |
| Dickeya dadantii 3937 | 0.65 | DDA3937_RS04925 | | NADP(H)-dependent aldo-keto reductase | 0.64 | DDA3937_RS10370 | | YchE family NAAT transporter | low | > 74 |
| Dickeya dianthicola ME23 | 0.65 | DZA65_RS05270 | | NADP(H)-dependent aldo-keto reductase | 0.63 | DZA65_RS10850 | | YchE family NAAT transporter | low | > 75 |
| Erwinia amylovora T8 | 0.65 | OLJFJH_09025 | | NADP(H)-dependent aldo-keto reductase | 0.61 | OLJFJH_13390 | | YchE family NAAT transporter | low | > 58 |
| Shewanella amazonensis SB2B | 0.64 | Sama_2776 | | aldo/keto reductase family oxidoreductase (RefSeq) | 0.55 | Sama_1694 | | hypothetical protein (RefSeq) | low | > 62 |
| Erwinia tracheiphila SCR3 | 0.64 | LU632_RS06080 | | NADP(H)-dependent aldo-keto reductase | 0.64 | LU632_RS12890 | | YchE family NAAT transporter | low | > 73 |
| Erwinia tracheiphila HP pepo 2.2 | 0.64 | IJEDHG_17095 | tas | NADP(H)-dependent aldo-keto reductase | 0.64 | IJEDHG_22725 | | YchE family NAAT transporter | low | > 61 |
| Pectobacterium carotovorum WPP14 | 0.64 | HER17_RS16605 | | NADP(H)-dependent aldo-keto reductase | 0.28 | HER17_RS05025 | | MarC family NAAT transporter | low | > 75 |
| Klebsiella pneumoniae MKP103 | 0.63 | KDGMDA_03880 | | NADP(H)-dependent aldo-keto reductase | 0.63 | KDGMDA_24480 | | YchE family NAAT transporter | low | > 95 |
| Klebsiella michiganensis M5al | 0.62 | BWI76_RS23305 | | NADP(H)-dependent aldo-keto reductase | 0.63 | BWI76_RS17245 | | hypothetical protein | low | > 92 |
| Escherichia coli Nissle 1917 | 0.62 | ECOLIN_RS15910 | | NADP(H)-dependent aldo-keto reductase | 0.63 | ECOLIN_RS07505 | | NAAT family transporter YchE | — | — |
| Escherichia coli ECOR38 | 0.62 | HEPCGN_19535 | tas | NADP(H)-dependent aldo-keto reductase | 0.63 | HEPCGN_25080 | ychE | NAAT family transporter YchE | low | > 88 |
| Escherichia fergusonii Becca | 0.62 | EFB2_01049 | | Protein tas | 0.63 | EFB2_02685 | | hypothetical protein | low | > 86 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.62 | OHPLBJKB_00895 | | Protein tas | 0.63 | OHPLBJKB_02443 | | hypothetical protein | low | > 74 |
| Escherichia coli ECOR27 | 0.62 | NOLOHH_11860 | tas | NADP(H)-dependent aldo-keto reductase | 0.63 | NOLOHH_20435 | ychE | NAAT family transporter YchE | low | > 76 |
| Escherichia coli ECRC62 | 0.62 | BNILDI_10340 | tas | NADP(H)-dependent aldo-keto reductase | 0.63 | BNILDI_18580 | ychE | NAAT family transporter YchE | low | > 75 |
| Escherichia coli BL21 | 0.62 | ECD_02682 | | putative NADP(H)-dependent aldo-keto reductase | 0.63 | ECD_01216 | | UPF0056 family inner membrane protein | low | > 61 |
| Escherichia coli BW25113 | 0.62 | b2834 | tas | predicted oxidoreductase, NADP(H)-dependent aldo-keto reductase (NCBI) | 0.63 | b1242 | ychE | predicted inner membrane protein (NCBI) | low | > 76 |
| Shewanella sp. ANA-3 | 0.62 | Shewana3_3379 | | aldo/keto reductase (RefSeq) | 0.52 | Shewana3_1789 | | hypothetical protein (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.62 | SO0900 | | oxidoreductase, aldo/keto reductase family (NCBI ptt file) | 0.52 | SO2137 | | conserved hypothetical protein TIGR00427 (NCBI ptt file) | low | > 76 |
| Escherichia coli ECRC102 | 0.62 | NIAGMN_17745 | tas | NADP(H)-dependent aldo-keto reductase | 0.63 | NIAGMN_27620 | ychE | NAAT family transporter YchE | 0.62 | 8 |
| Escherichia coli ECRC101 | 0.62 | MCAODC_10500 | tas | NADP(H)-dependent aldo-keto reductase | 0.63 | MCAODC_21645 | ychE | NAAT family transporter YchE | low | > 87 |
| Escherichia coli ECRC98 | 0.62 | JDDGAC_23640 | tas | NADP(H)-dependent aldo-keto reductase | 0.63 | JDDGAC_05960 | ychE | NAAT family transporter YchE | low | > 87 |
| Escherichia coli ECRC99 | 0.62 | KEDOAH_08155 | tas | NADP(H)-dependent aldo-keto reductase | 0.63 | KEDOAH_25610 | ychE | NAAT family transporter YchE | — | — |
| Escherichia coli ECRC100 | 0.62 | OKFHMN_19975 | tas | NADP(H)-dependent aldo-keto reductase | 0.63 | OKFHMN_28615 | ychE | NAAT family transporter YchE | low | > 79 |
| Enterobacter asburiae PDN3 | 0.61 | EX28DRAFT_2908 | | Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) | 0.64 | EX28DRAFT_0866 | | membrane protein, MarC family | low | > 76 |
| Enterobacter sp. TBS_079 | 0.61 | MPMX20_03696 | | Protein tas | 0.64 | MPMX20_02588 | | hypothetical protein | low | > 85 |
| Marinobacter adhaerens HP15 | 0.59 | HP15_740 | | oxidoreductase Tas, aldo/keto reductase family protein | 0.20 | HP15_3589 | | multiple antibiotic resistance (MarC)-related protein | low | > 73 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.58 | GFF1317 | | Oxidoreductase, aldo/keto reductase family | 0.63 | GFF2748 | | Putative membrane protein | low | > 78 |
| Herbaspirillum seropedicae SmR1 | 0.57 | HSERO_RS13630 | | aldo-keto reductase | 0.18 | HSERO_RS21710 | | antibiotic resistance protein MarC | low | > 78 |
| Pseudomonas fluorescens GW456-L13 | 0.57 | PfGW456L13_1631 | | Oxidoreductase, aldo/keto reductase family | 0.22 | PfGW456L13_60 | | membrane protein, MarC family | low | > 87 |
| Pseudomonas sp. RS175 | 0.57 | PFR28_03609 | | Protein tas | 0.23 | PFR28_05211 | | hypothetical protein | low | > 88 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.57 | H281DRAFT_00770 | | Predicted oxidoreductase | 0.38 | H281DRAFT_05656 | | multiple antibiotic resistance protein | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.57 | AO356_17050 | | aldo/keto reductase | 0.22 | AO356_08255 | | hypothetical protein | low | > 104 |
| Paraburkholderia graminis OAS925 | 0.57 | ABIE53_001982 | | aryl-alcohol dehydrogenase-like predicted oxidoreductase | 0.39 | ABIE53_003698 | | multiple antibiotic resistance protein | low | > 113 |
| Pseudomonas fluorescens FW300-N2E2 | 0.57 | Pf6N2E2_5334 | | Oxidoreductase, aldo/keto reductase family | 0.22 | Pf6N2E2_3525 | | membrane protein, MarC family | low | > 103 |
| Pseudomonas sp. DMC3 | 0.56 | GFF4440 | | Protein tas | 0.23 | GFF3305 | | hypothetical protein | low | > 89 |
| Pseudomonas lactucae CFBP13502 | 0.56 | GEMAOFIL_01033 | | Protein tas | 0.22 | GEMAOFIL_00817 | | hypothetical protein | low | > 96 |
| Pseudomonas fluorescens FW300-N1B4 | 0.56 | Pf1N1B4_965 | | Oxidoreductase, aldo/keto reductase family | 0.23 | Pf1N1B4_1320 | | membrane protein, MarC family | low | > 87 |
| Pseudomonas orientalis W4I3 | 0.56 | QF045_RS07140 | | NADP(H)-dependent aldo-keto reductase | 0.22 | QF045_RS05955 | | MarC family protein | low | > 93 |
| Pseudomonas simiae WCS417 | 0.56 | PS417_04140 | | aldo/keto reductase | 0.22 | PS417_02925 | | membrane protein | low | > 88 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.56 | Psyr_2296 | | Aldo/keto reductase | 0.23 | Psyr_4409 | | Multiple antibiotic resistance (MarC)-related protein | low | > 86 |
| Burkholderia phytofirmans PsJN | 0.56 | BPHYT_RS08735 | | aldo-keto reductase | 0.37 | BPHYT_RS17695 | | membrane protein | low | > 109 |
| Pseudomonas syringae pv. syringae B728a | 0.56 | Psyr_2296 | | Aldo/keto reductase | 0.23 | Psyr_4409 | | Multiple antibiotic resistance (MarC)-related protein | low | > 86 |
| Paraburkholderia sabiae LMG 24235 | 0.56 | QEN71_RS22635 | | NADP(H)-dependent aldo-keto reductase | 0.37 | QEN71_RS27850 | | MarC family protein | low | > 153 |
| Pseudomonas fluorescens SBW25-INTG | 0.56 | PFLU_RS04180 | | NADP(H)-dependent aldo-keto reductase | 0.22 | PFLU_RS03000 | | MarC family protein | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.56 | PFLU_RS04180 | | NADP(H)-dependent aldo-keto reductase | 0.22 | PFLU_RS03000 | | MarC family protein | low | > 109 |
| Pseudomonas segetis P6 | 0.55 | MPMX49_03831 | | Protein tas | 0.22 | MPMX49_04111 | | hypothetical protein | low | > 75 |
| Pseudomonas aeruginosa PA14 | 0.55 | IKLFDK_01920 | | NADP(H)-dependent aldo-keto reductase | 0.22 | IKLFDK_27445 | | MarC family NAAT transporter | low | > 98 |
| Pseudomonas fluorescens FW300-N2E3 | 0.55 | AO353_15230 | | aldo/keto reductase | 0.22 | AO353_13635 | | hypothetical protein | low | > 101 |
| Pseudomonas sp. S08-1 | 0.55 | OH686_08405 | | Tas protein, an NADP(H)-dependent aldo-keto reductase | 0.21 | OH686_07645 | | MarC family integral membrane protein | low | > 80 |
| Pseudomonas sp. BP01 | 0.55 | JOY50_RS04515 | | NADP(H)-dependent aldo-keto reductase | 0.22 | JOY50_RS17610 | | MarC family protein | low | > 84 |
| Pseudomonas aeruginosa MRSN321 | 0.55 | DY961_RS24305 | | NADP(H)-dependent aldo-keto reductase | 0.22 | DY961_RS11895 | | MarC family NAAT transporter | 0.26 | 29 |
| Pseudomonas aeruginosa PUPa3 | 0.55 | DQ20_RS56765 | | NADP(H)-dependent aldo-keto reductase | 0.22 | DQ20_RS50220 | | MarC family NAAT transporter | low | > 101 |
| Azospirillum brasilense Sp245 | 0.55 | AZOBR_RS02275 | | aldo-keto reductase | 0.26 | AZOBR_RS25935 | | antibiotic resistance protein | low | > 97 |
| Pseudomonas putida KT2440 | 0.55 | PP_1314 | | putative NAD(P)-linked reductase | 0.22 | PP_4825 | | Membrane protein, MarC family | low | > 96 |
| Pseudomonas sp. SVBP6 | 0.54 | COO64_RS11780 | | NADP(H)-dependent aldo-keto reductase | 0.22 | COO64_RS18290 | | MarC family protein | low | > 93 |
| Sphingobium sp. HT1-2 | 0.53 | GFF3847 | | Tas protein, an NADP(H)-dependent aldo-keto reductase | 0.23 | GFF2783 | | MarC family integral membrane protein | low | > 95 |
| Azospirillum sp. SherDot2 | 0.52 | MPMX19_02594 | | Protein tas | 0.23 | MPMX19_05023 | | hypothetical protein | low | > 112 |
| Xanthobacter sp. DMC5 | 0.50 | GFF3423 | | Protein tas | 0.28 | GFF1576 | | hypothetical protein | — | — |
| Bosea sp. OAE506 | 0.50 | ABIE41_RS04820 | | aldo/keto reductase | 0.27 | ABIE41_RS15150 | | MarC family protein | — | — |
| Cellulophaga baltica 18 | 0.49 | M666_RS03600 | | aldo/keto reductase | 0.25 | M666_RS11715 | | MarC family protein | low | > 67 |
| Cupriavidus basilensis FW507-4G11 | 0.49 | RR42_RS07460 | | aldo/keto reductase | 0.37 | RR42_RS18900 | | membrane protein | low | > 128 |
| Caulobacter crescentus NA1000 | 0.48 | CCNA_03777 | | Tas protein | 0.25 | CCNA_00105 | | MarC family integral membrane protein | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.48 | CCNA_03777 | | Tas protein | 0.25 | CCNA_00105 | | MarC family integral membrane protein | — | — |
| Agrobacterium fabrum C58 | 0.48 | Atu1093 | | aldo/keto reductase | 0.28 | Atu1508 | | hypothetical protein | low | > 89 |
| Rhizobium sp. OAE497 | 0.48 | ABIE40_RS06350 | | aldo/keto reductase | 0.27 | ABIE40_RS09370 | | MarC family protein | low | > 107 |
| Sinorhizobium meliloti 1021 | 0.46 | SMc00570 | | oxidoreductase | 0.31 | SMc01232 | | hypothetical protein | low | > 103 |
| Acidovorax sp. GW101-3H11 | 0.44 | Ac3H11_2629 | | Oxidoreductase | 0.32 | Ac3H11_2153 | | Multiple antibiotic resistance (MarC) -related proteins | low | > 79 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.42 | GFF287 | | Oxidoreductase | 0.34 | GFF1820 | | Multiple antibiotic resistance protein marC | low | > 90 |
| Methylophilus sp. DMC18 | 0.42 | GFF1878 | | Protein tas | 0.43 | GFF2552 | | hypothetical protein | low | > 43 |
| Variovorax sp. SCN45 | 0.41 | GFF3105 | | Tas protein, an NADP(H)-dependent aldo-keto reductase | 0.28 | GFF3614 | | UPF0056 inner membrane protein YchE | low | > 127 |
| Phaeobacter inhibens DSM 17395 | 0.41 | PGA1_c08380 | | protein Tas | 0.26 | PGA1_c19770 | | membrane protein, MarC family | low | > 62 |
| Dinoroseobacter shibae DFL-12 | 0.40 | Dshi_2823 | | aldo/keto reductase (RefSeq) | 0.26 | Dshi_1348 | | multiple antibiotic resistance (MarC)-related protein (RefSeq) | low | > 64 |
| Alteromonas macleodii MIT1002 | 0.40 | MIT1002_03519 | | L-glyceraldehyde 3-phosphate reductase | 0.15 | MIT1002_03685 | | putative antibiotic transporter | low | > 70 |
| Variovorax sp. OAS795 | 0.40 | ABID97_RS21710 | | aldo/keto reductase | 0.26 | ABID97_RS00755 | | MarC family protein | low | > 91 |
| Dyella japonica UNC79MFTsu3.2 | 0.26 | ABZR86_RS17730 | | aldo/keto reductase | 0.12 | ABZR86_RS09810 | | YhgN family NAAT transporter | low | > 74 |
| Rhodanobacter sp. FW510-T8 | 0.24 | OKGIIK_16170 | pdxI | Pyridoxal reductase PdxI or related oxidoreductase, aldo/keto reductase family | 0.14 | OKGIIK_03070 | marC | YhgN family NAAT transporter | low | > 53 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.23 | Xcc-8004.348.1 | | Oxidoreductase | 0.16 | Xcc-8004.2016.1 | | FIG01210190: hypothetical protein | — | — |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.23 | ABZR88_RS09880 | | aldo/keto reductase | 0.18 | ABZR88_RS11625 | | MarC family protein | — | — |
| Rhodanobacter sp000427505 FW510-R12 | 0.23 | LRK53_RS02685 | | aldo/keto reductase | 0.14 | LRK53_RS14765 | | YhgN family NAAT transporter | — | — |
| Rhodanobacter denitrificans MT42 | 0.23 | LRK55_RS09560 | | aldo/keto reductase | 0.13 | LRK55_RS13550 | | YhgN family NAAT transporter | low | > 63 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.22 | Echvi_4511 | | Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) | 0.19 | Echvi_1812 | | membrane protein, MarC family | low | > 79 |
| Rhodanobacter denitrificans FW104-10B01 | 0.22 | LRK54_RS09920 | | aldo/keto reductase | 0.13 | LRK54_RS13835 | | YhgN family NAAT transporter | low | > 59 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.22 | A4249_RS00675 | | aldo/keto reductase | 0.22 | A4249_RS14670 | | MarC family protein | — | — |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.21 | CA264_00520 | | alcohol dehydrogenase | 0.29 | CA264_12605 | | stress protection protein MarC | low | > 74 |
| Sphingomonas koreensis DSMZ 15582 | 0.21 | Ga0059261_3340 | | Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) | 0.25 | Ga0059261_1304 | | membrane protein, MarC family | low | > 68 |
| Ralstonia sp. UNC404CL21Col | 0.21 | ABZR87_RS20800 | | aldo/keto reductase | 0.39 | ABZR87_RS02485 | | MarC family protein | low | > 80 |
| Lysobacter sp. OAE881 | 0.21 | ABIE51_RS00630 | | aldo/keto reductase | 0.25 | ABIE51_RS10495 | | MarC family NAAT transporter | low | > 62 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.21 | CA265_RS14335 | | alcohol dehydrogenase | 0.16 | CA265_RS15010 | | hypothetical protein | low | > 88 |
| Ralstonia solanacearum IBSBF1503 | 0.20 | RALBFv3_RS17145 | | aldo/keto reductase | 0.39 | RALBFv3_RS06830 | | membrane protein | — | — |
| Ralstonia solanacearum GMI1000 | 0.20 | RS_RS24225 | | aldo/keto reductase | 0.39 | RS_RS14775 | | membrane protein | — | — |
| Ralstonia solanacearum PSI07 | 0.19 | RPSI07_RS06465 | | aldo/keto reductase | 0.36 | RPSI07_RS10405 | | membrane protein | — | — |
| Parabacteroides merdae CL09T00C40 | 0.16 | HMPREF1078_RS09495 | | L-glyceraldehyde 3-phosphate reductase | 0.30 | HMPREF1078_RS08220 | | MarC family protein | low | > 61 |
| Bacteroides stercoris CC31F | 0.15 | HMPREF1181_RS03645 | | aldo/keto reductase | 0.30 | HMPREF1181_RS13025 | | MarC family protein | low | > 56 |
| Phocaeicola dorei CL03T12C01 | 0.15 | ABI39_RS07100 | | aldo/keto reductase | 0.28 | ABI39_RS01190 | | NAAT family transporter | low | > 72 |
| Bacteroides ovatus ATCC 8483 | 0.15 | BACOVA_00975 | | oxidoreductase, aldo/keto reductase family protein | 0.24 | BACOVA_03076 | | membrane protein, MarC family | low | > 96 |
| Rhodospirillum rubrum S1H | 0.15 | Rru_A1059 | | Aldo/keto reductase (NCBI) | 0.29 | Rru_A0654 | | Multiple antibiotic resistance (MarC)-related proteins (NCBI) | low | > 58 |
| Phocaeicola vulgatus CL09T03C04 | 0.15 | HMPREF1058_RS09580 | | aldo/keto reductase | 0.30 | HMPREF1058_RS05435 | | MarC family protein | low | > 67 |
| Castellaniella sp019104865 MT123 | 0.13 | ABCV34_RS02780 | | aldo/keto reductase | 0.26 | ABCV34_RS00685 | | MarC family protein | low | > 48 |
| Ralstonia solanacearum UW163 | 0.13 | UW163_RS23080 | | aldo/keto reductase | 0.39 | UW163_RS06785 | | membrane protein | — | — |
| Bifidobacterium breve UCC2003 | 0.12 | BBR_RS12385 | | oxidoreductase | 0.22 | BBR_RS19245 | | membrane protein | low | > 34 |
| Synechococcus elongatus PCC 7942 | 0.12 | Synpcc7942_0026 | | hypothetical protein | 0.26 | Synpcc7942_2083 | | Multiple antibiotic resistance (MarC)-related proteins | low | > 38 |
Not shown: 9 genomes with orthologs for CSW01_03510 only; 4 genomes with orthologs for CSW01_10170 only