Conservation of cofitness between CSW01_03510 and CSW01_10170 in Vibrio cholerae E7946 ATCC 55056

108 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_03510 NADP(H)-dependent aldo-keto reductase 1.0 CSW01_10170 MarC family protein 0.71 3
Serratia liquefaciens MT49 0.66 IAI46_20475 NADP(H)-dependent aldo-keto reductase 0.63 IAI46_14215 YchE family NAAT transporter low > 87
Pantoea sp. MT58 0.65 IAI47_03895 NADP(H)-dependent aldo-keto reductase 0.64 IAI47_09060 YchE family NAAT transporter low > 76
Shewanella loihica PV-4 0.65 Shew_0736 aldo/keto reductase (RefSeq) 0.55 Shew_1911 hypothetical protein (RefSeq)
Rahnella sp. WP5 0.65 EX31_RS13220 NADP(H)-dependent aldo-keto reductase 0.64 EX31_RS10070 YchE family NAAT transporter low > 89
Pantoea agglomerans CFBP13505 P0401 0.65 PagCFBP13505_RS17075 NADP(H)-dependent aldo-keto reductase 0.64 PagCFBP13505_RS02900 YchE family NAAT transporter low > 74
Dickeya dianthicola 67-19 0.65 HGI48_RS04935 NADP(H)-dependent aldo-keto reductase 0.64 HGI48_RS10375 YchE family NAAT transporter low > 71
Dickeya dadantii 3937 0.65 DDA3937_RS04925 NADP(H)-dependent aldo-keto reductase 0.64 DDA3937_RS10370 YchE family NAAT transporter low > 74
Dickeya dianthicola ME23 0.65 DZA65_RS05270 NADP(H)-dependent aldo-keto reductase 0.63 DZA65_RS10850 YchE family NAAT transporter low > 75
Erwinia amylovora T8 0.65 OLJFJH_09025 NADP(H)-dependent aldo-keto reductase 0.61 OLJFJH_13390 YchE family NAAT transporter low > 58
Shewanella amazonensis SB2B 0.64 Sama_2776 aldo/keto reductase family oxidoreductase (RefSeq) 0.55 Sama_1694 hypothetical protein (RefSeq) low > 62
Erwinia tracheiphila SCR3 0.64 LU632_RS06080 NADP(H)-dependent aldo-keto reductase 0.64 LU632_RS12890 YchE family NAAT transporter low > 73
Erwinia tracheiphila HP pepo 2.2 0.64 IJEDHG_17095 tas NADP(H)-dependent aldo-keto reductase 0.64 IJEDHG_22725 YchE family NAAT transporter low > 61
Pectobacterium carotovorum WPP14 0.64 HER17_RS16605 NADP(H)-dependent aldo-keto reductase 0.28 HER17_RS05025 MarC family NAAT transporter low > 75
Klebsiella pneumoniae MKP103 0.63 KDGMDA_03880 NADP(H)-dependent aldo-keto reductase 0.63 KDGMDA_24480 YchE family NAAT transporter low > 95
Klebsiella michiganensis M5al 0.62 BWI76_RS23305 NADP(H)-dependent aldo-keto reductase 0.63 BWI76_RS17245 hypothetical protein low > 92
Escherichia coli Nissle 1917 0.62 ECOLIN_RS15910 NADP(H)-dependent aldo-keto reductase 0.63 ECOLIN_RS07505 NAAT family transporter YchE
Escherichia coli ECOR38 0.62 HEPCGN_19535 tas NADP(H)-dependent aldo-keto reductase 0.63 HEPCGN_25080 ychE NAAT family transporter YchE low > 88
Escherichia fergusonii Becca 0.62 EFB2_01049 Protein tas 0.63 EFB2_02685 hypothetical protein low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.62 OHPLBJKB_00895 Protein tas 0.63 OHPLBJKB_02443 hypothetical protein low > 74
Escherichia coli ECOR27 0.62 NOLOHH_11860 tas NADP(H)-dependent aldo-keto reductase 0.63 NOLOHH_20435 ychE NAAT family transporter YchE low > 76
Escherichia coli ECRC62 0.62 BNILDI_10340 tas NADP(H)-dependent aldo-keto reductase 0.63 BNILDI_18580 ychE NAAT family transporter YchE low > 75
Escherichia coli BL21 0.62 ECD_02682 putative NADP(H)-dependent aldo-keto reductase 0.63 ECD_01216 UPF0056 family inner membrane protein low > 61
Escherichia coli BW25113 0.62 b2834 tas predicted oxidoreductase, NADP(H)-dependent aldo-keto reductase (NCBI) 0.63 b1242 ychE predicted inner membrane protein (NCBI) low > 76
Shewanella sp. ANA-3 0.62 Shewana3_3379 aldo/keto reductase (RefSeq) 0.52 Shewana3_1789 hypothetical protein (RefSeq) low > 73
Shewanella oneidensis MR-1 0.62 SO0900 oxidoreductase, aldo/keto reductase family (NCBI ptt file) 0.52 SO2137 conserved hypothetical protein TIGR00427 (NCBI ptt file) low > 76
Escherichia coli ECRC102 0.62 NIAGMN_17745 tas NADP(H)-dependent aldo-keto reductase 0.63 NIAGMN_27620 ychE NAAT family transporter YchE 0.62 8
Escherichia coli ECRC101 0.62 MCAODC_10500 tas NADP(H)-dependent aldo-keto reductase 0.63 MCAODC_21645 ychE NAAT family transporter YchE low > 87
Escherichia coli ECRC98 0.62 JDDGAC_23640 tas NADP(H)-dependent aldo-keto reductase 0.63 JDDGAC_05960 ychE NAAT family transporter YchE low > 87
Escherichia coli ECRC99 0.62 KEDOAH_08155 tas NADP(H)-dependent aldo-keto reductase 0.63 KEDOAH_25610 ychE NAAT family transporter YchE
Escherichia coli ECRC100 0.62 OKFHMN_19975 tas NADP(H)-dependent aldo-keto reductase 0.63 OKFHMN_28615 ychE NAAT family transporter YchE low > 79
Enterobacter asburiae PDN3 0.61 EX28DRAFT_2908 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) 0.64 EX28DRAFT_0866 membrane protein, MarC family low > 76
Enterobacter sp. TBS_079 0.61 MPMX20_03696 Protein tas 0.64 MPMX20_02588 hypothetical protein low > 85
Marinobacter adhaerens HP15 0.59 HP15_740 oxidoreductase Tas, aldo/keto reductase family protein 0.20 HP15_3589 multiple antibiotic resistance (MarC)-related protein low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.58 GFF1317 Oxidoreductase, aldo/keto reductase family 0.63 GFF2748 Putative membrane protein low > 78
Herbaspirillum seropedicae SmR1 0.57 HSERO_RS13630 aldo-keto reductase 0.18 HSERO_RS21710 antibiotic resistance protein MarC low > 78
Pseudomonas fluorescens GW456-L13 0.57 PfGW456L13_1631 Oxidoreductase, aldo/keto reductase family 0.22 PfGW456L13_60 membrane protein, MarC family low > 87
Pseudomonas sp. RS175 0.57 PFR28_03609 Protein tas 0.23 PFR28_05211 hypothetical protein low > 88
Paraburkholderia bryophila 376MFSha3.1 0.57 H281DRAFT_00770 Predicted oxidoreductase 0.38 H281DRAFT_05656 multiple antibiotic resistance protein low > 103
Pseudomonas fluorescens FW300-N2C3 0.57 AO356_17050 aldo/keto reductase 0.22 AO356_08255 hypothetical protein low > 104
Paraburkholderia graminis OAS925 0.57 ABIE53_001982 aryl-alcohol dehydrogenase-like predicted oxidoreductase 0.39 ABIE53_003698 multiple antibiotic resistance protein low > 113
Pseudomonas fluorescens FW300-N2E2 0.57 Pf6N2E2_5334 Oxidoreductase, aldo/keto reductase family 0.22 Pf6N2E2_3525 membrane protein, MarC family low > 103
Pseudomonas sp. DMC3 0.56 GFF4440 Protein tas 0.23 GFF3305 hypothetical protein low > 89
Pseudomonas lactucae CFBP13502 0.56 GEMAOFIL_01033 Protein tas 0.22 GEMAOFIL_00817 hypothetical protein low > 96
Pseudomonas fluorescens FW300-N1B4 0.56 Pf1N1B4_965 Oxidoreductase, aldo/keto reductase family 0.23 Pf1N1B4_1320 membrane protein, MarC family low > 87
Pseudomonas orientalis W4I3 0.56 QF045_RS07140 NADP(H)-dependent aldo-keto reductase 0.22 QF045_RS05955 MarC family protein low > 93
Pseudomonas simiae WCS417 0.56 PS417_04140 aldo/keto reductase 0.22 PS417_02925 membrane protein low > 88
Pseudomonas syringae pv. syringae B728a ΔmexB 0.56 Psyr_2296 Aldo/keto reductase 0.23 Psyr_4409 Multiple antibiotic resistance (MarC)-related protein low > 86
Burkholderia phytofirmans PsJN 0.56 BPHYT_RS08735 aldo-keto reductase 0.37 BPHYT_RS17695 membrane protein low > 109
Pseudomonas syringae pv. syringae B728a 0.56 Psyr_2296 Aldo/keto reductase 0.23 Psyr_4409 Multiple antibiotic resistance (MarC)-related protein low > 86
Paraburkholderia sabiae LMG 24235 0.56 QEN71_RS22635 NADP(H)-dependent aldo-keto reductase 0.37 QEN71_RS27850 MarC family protein low > 153
Pseudomonas fluorescens SBW25-INTG 0.56 PFLU_RS04180 NADP(H)-dependent aldo-keto reductase 0.22 PFLU_RS03000 MarC family protein low > 109
Pseudomonas fluorescens SBW25 0.56 PFLU_RS04180 NADP(H)-dependent aldo-keto reductase 0.22 PFLU_RS03000 MarC family protein low > 109
Pseudomonas segetis P6 0.55 MPMX49_03831 Protein tas 0.22 MPMX49_04111 hypothetical protein low > 75
Pseudomonas aeruginosa PA14 0.55 IKLFDK_01920 NADP(H)-dependent aldo-keto reductase 0.22 IKLFDK_27445 MarC family NAAT transporter low > 98
Pseudomonas fluorescens FW300-N2E3 0.55 AO353_15230 aldo/keto reductase 0.22 AO353_13635 hypothetical protein low > 101
Pseudomonas sp. S08-1 0.55 OH686_08405 Tas protein, an NADP(H)-dependent aldo-keto reductase 0.21 OH686_07645 MarC family integral membrane protein low > 80
Pseudomonas sp. BP01 0.55 JOY50_RS04515 NADP(H)-dependent aldo-keto reductase 0.22 JOY50_RS17610 MarC family protein low > 84
Pseudomonas aeruginosa MRSN321 0.55 DY961_RS24305 NADP(H)-dependent aldo-keto reductase 0.22 DY961_RS11895 MarC family NAAT transporter 0.26 29
Pseudomonas aeruginosa PUPa3 0.55 DQ20_RS56765 NADP(H)-dependent aldo-keto reductase 0.22 DQ20_RS50220 MarC family NAAT transporter low > 101
Azospirillum brasilense Sp245 0.55 AZOBR_RS02275 aldo-keto reductase 0.26 AZOBR_RS25935 antibiotic resistance protein low > 97
Pseudomonas putida KT2440 0.55 PP_1314 putative NAD(P)-linked reductase 0.22 PP_4825 Membrane protein, MarC family low > 96
Pseudomonas sp. SVBP6 0.54 COO64_RS11780 NADP(H)-dependent aldo-keto reductase 0.22 COO64_RS18290 MarC family protein low > 93
Sphingobium sp. HT1-2 0.53 GFF3847 Tas protein, an NADP(H)-dependent aldo-keto reductase 0.23 GFF2783 MarC family integral membrane protein low > 95
Azospirillum sp. SherDot2 0.52 MPMX19_02594 Protein tas 0.23 MPMX19_05023 hypothetical protein low > 112
Xanthobacter sp. DMC5 0.50 GFF3423 Protein tas 0.28 GFF1576 hypothetical protein
Bosea sp. OAE506 0.50 ABIE41_RS04820 aldo/keto reductase 0.27 ABIE41_RS15150 MarC family protein
Cellulophaga baltica 18 0.49 M666_RS03600 aldo/keto reductase 0.25 M666_RS11715 MarC family protein low > 67
Cupriavidus basilensis FW507-4G11 0.49 RR42_RS07460 aldo/keto reductase 0.37 RR42_RS18900 membrane protein low > 128
Caulobacter crescentus NA1000 0.48 CCNA_03777 Tas protein 0.25 CCNA_00105 MarC family integral membrane protein
Caulobacter crescentus NA1000 Δfur 0.48 CCNA_03777 Tas protein 0.25 CCNA_00105 MarC family integral membrane protein
Agrobacterium fabrum C58 0.48 Atu1093 aldo/keto reductase 0.28 Atu1508 hypothetical protein low > 89
Rhizobium sp. OAE497 0.48 ABIE40_RS06350 aldo/keto reductase 0.27 ABIE40_RS09370 MarC family protein low > 107
Sinorhizobium meliloti 1021 0.46 SMc00570 oxidoreductase 0.31 SMc01232 hypothetical protein low > 103
Acidovorax sp. GW101-3H11 0.44 Ac3H11_2629 Oxidoreductase 0.32 Ac3H11_2153 Multiple antibiotic resistance (MarC) -related proteins low > 79
Hydrogenophaga sp. GW460-11-11-14-LB1 0.42 GFF287 Oxidoreductase 0.34 GFF1820 Multiple antibiotic resistance protein marC low > 90
Methylophilus sp. DMC18 0.42 GFF1878 Protein tas 0.43 GFF2552 hypothetical protein low > 43
Variovorax sp. SCN45 0.41 GFF3105 Tas protein, an NADP(H)-dependent aldo-keto reductase 0.28 GFF3614 UPF0056 inner membrane protein YchE low > 127
Phaeobacter inhibens DSM 17395 0.41 PGA1_c08380 protein Tas 0.26 PGA1_c19770 membrane protein, MarC family low > 62
Dinoroseobacter shibae DFL-12 0.40 Dshi_2823 aldo/keto reductase (RefSeq) 0.26 Dshi_1348 multiple antibiotic resistance (MarC)-related protein (RefSeq) low > 64
Alteromonas macleodii MIT1002 0.40 MIT1002_03519 L-glyceraldehyde 3-phosphate reductase 0.15 MIT1002_03685 putative antibiotic transporter low > 70
Variovorax sp. OAS795 0.40 ABID97_RS21710 aldo/keto reductase 0.26 ABID97_RS00755 MarC family protein low > 91
Dyella japonica UNC79MFTsu3.2 0.26 ABZR86_RS17730 aldo/keto reductase 0.12 ABZR86_RS09810 YhgN family NAAT transporter low > 74
Rhodanobacter sp. FW510-T8 0.24 OKGIIK_16170 pdxI Pyridoxal reductase PdxI or related oxidoreductase, aldo/keto reductase family 0.14 OKGIIK_03070 marC YhgN family NAAT transporter low > 53
Xanthomonas campestris pv. campestris strain 8004 0.23 Xcc-8004.348.1 Oxidoreductase 0.16 Xcc-8004.2016.1 FIG01210190: hypothetical protein
Mucilaginibacter yixingensis YX-36 DSM 26809 0.23 ABZR88_RS09880 aldo/keto reductase 0.18 ABZR88_RS11625 MarC family protein
Rhodanobacter sp000427505 FW510-R12 0.23 LRK53_RS02685 aldo/keto reductase 0.14 LRK53_RS14765 YhgN family NAAT transporter
Rhodanobacter denitrificans MT42 0.23 LRK55_RS09560 aldo/keto reductase 0.13 LRK55_RS13550 YhgN family NAAT transporter low > 63
Echinicola vietnamensis KMM 6221, DSM 17526 0.22 Echvi_4511 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) 0.19 Echvi_1812 membrane protein, MarC family low > 79
Rhodanobacter denitrificans FW104-10B01 0.22 LRK54_RS09920 aldo/keto reductase 0.13 LRK54_RS13835 YhgN family NAAT transporter low > 59
Brevundimonas sp. GW460-12-10-14-LB2 0.22 A4249_RS00675 aldo/keto reductase 0.22 A4249_RS14670 MarC family protein
Pontibacter actiniarum KMM 6156, DSM 19842 0.21 CA264_00520 alcohol dehydrogenase 0.29 CA264_12605 stress protection protein MarC low > 74
Sphingomonas koreensis DSMZ 15582 0.21 Ga0059261_3340 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) 0.25 Ga0059261_1304 membrane protein, MarC family low > 68
Ralstonia sp. UNC404CL21Col 0.21 ABZR87_RS20800 aldo/keto reductase 0.39 ABZR87_RS02485 MarC family protein low > 80
Lysobacter sp. OAE881 0.21 ABIE51_RS00630 aldo/keto reductase 0.25 ABIE51_RS10495 MarC family NAAT transporter low > 62
Pedobacter sp. GW460-11-11-14-LB5 0.21 CA265_RS14335 alcohol dehydrogenase 0.16 CA265_RS15010 hypothetical protein low > 88
Ralstonia solanacearum IBSBF1503 0.20 RALBFv3_RS17145 aldo/keto reductase 0.39 RALBFv3_RS06830 membrane protein
Ralstonia solanacearum GMI1000 0.20 RS_RS24225 aldo/keto reductase 0.39 RS_RS14775 membrane protein
Ralstonia solanacearum PSI07 0.19 RPSI07_RS06465 aldo/keto reductase 0.36 RPSI07_RS10405 membrane protein
Parabacteroides merdae CL09T00C40 0.16 HMPREF1078_RS09495 L-glyceraldehyde 3-phosphate reductase 0.30 HMPREF1078_RS08220 MarC family protein low > 61
Bacteroides stercoris CC31F 0.15 HMPREF1181_RS03645 aldo/keto reductase 0.30 HMPREF1181_RS13025 MarC family protein low > 56
Phocaeicola dorei CL03T12C01 0.15 ABI39_RS07100 aldo/keto reductase 0.28 ABI39_RS01190 NAAT family transporter low > 72
Bacteroides ovatus ATCC 8483 0.15 BACOVA_00975 oxidoreductase, aldo/keto reductase family protein 0.24 BACOVA_03076 membrane protein, MarC family low > 96
Rhodospirillum rubrum S1H 0.15 Rru_A1059 Aldo/keto reductase (NCBI) 0.29 Rru_A0654 Multiple antibiotic resistance (MarC)-related proteins (NCBI) low > 58
Phocaeicola vulgatus CL09T03C04 0.15 HMPREF1058_RS09580 aldo/keto reductase 0.30 HMPREF1058_RS05435 MarC family protein low > 67
Castellaniella sp019104865 MT123 0.13 ABCV34_RS02780 aldo/keto reductase 0.26 ABCV34_RS00685 MarC family protein low > 48
Ralstonia solanacearum UW163 0.13 UW163_RS23080 aldo/keto reductase 0.39 UW163_RS06785 membrane protein
Bifidobacterium breve UCC2003 0.12 BBR_RS12385 oxidoreductase 0.22 BBR_RS19245 membrane protein low > 34
Synechococcus elongatus PCC 7942 0.12 Synpcc7942_0026 hypothetical protein 0.26 Synpcc7942_2083 Multiple antibiotic resistance (MarC)-related proteins low > 38

Not shown: 9 genomes with orthologs for CSW01_03510 only; 4 genomes with orthologs for CSW01_10170 only