Conservation of cofitness between BWI76_RS20350 and BWI76_RS04665 in Klebsiella michiganensis M5al

91 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS20350 amidophosphoribosyltransferase 1.0 BWI76_RS04665 3-isopropylmalate dehydratase small subunit 0.83 15
Enterobacter sp. TBS_079 0.98 MPMX20_03247 Amidophosphoribosyltransferase 0.93 MPMX20_00766 3-isopropylmalate dehydratase small subunit 1 0.80 54
Enterobacter asburiae PDN3 0.98 EX28DRAFT_0292 amidophosphoribosyltransferase (EC 2.4.2.14) 0.92 EX28DRAFT_3667 3-isopropylmalate dehydratase, small subunit low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.98 GFF1927 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.93 GFF167 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.36 50
Escherichia coli BW25113 0.97 b2312 purF amidophosphoribosyltransferase (NCBI) 0.88 b0071 leuD isopropylmalate isomerase small subunit (NCBI) 0.75 55
Escherichia coli ECOR27 0.97 NOLOHH_14335 purF amidophosphoribosyltransferase 0.88 NOLOHH_03075 leuD 3-isopropylmalate dehydratase small subunit low > 75
Escherichia coli BL21 0.97 ECD_02237 amidophosphoribosyltransferase 0.88 ECD_00073 3-isopropylmalate dehydratase small subunit low > 61
Escherichia coli ECRC62 0.97 BNILDI_13255 purF amidophosphoribosyltransferase 0.88 BNILDI_08535 leuD 3-isopropylmalate dehydratase small subunit 0.78 59
Escherichia coli ECRC102 0.96 NIAGMN_20485 purF amidophosphoribosyltransferase 0.87 NIAGMN_08580 leuD 3-isopropylmalate dehydratase small subunit
Escherichia coli ECRC101 0.96 MCAODC_13755 purF amidophosphoribosyltransferase 0.87 MCAODC_01245 leuD 3-isopropylmalate dehydratase small subunit low > 87
Escherichia coli ECOR38 0.96 HEPCGN_21910 purF amidophosphoribosyltransferase 0.88 HEPCGN_08710 leuD 3-isopropylmalate dehydratase small subunit 0.71 71
Escherichia coli ECRC99 0.96 KEDOAH_05480 purF amidophosphoribosyltransferase 0.87 KEDOAH_17425 leuD 3-isopropylmalate dehydratase small subunit
Escherichia coli ECRC98 0.96 JDDGAC_26675 purF amidophosphoribosyltransferase 0.87 JDDGAC_14325 leuD 3-isopropylmalate dehydratase small subunit low > 86
Escherichia coli Nissle 1917 0.96 ECOLIN_RS13405 amidophosphoribosyltransferase 0.88 ECOLIN_RS00385 3-isopropylmalate dehydratase small subunit
Escherichia coli ECRC100 0.96 OKFHMN_22715 purF amidophosphoribosyltransferase 0.87 OKFHMN_10730 leuD 3-isopropylmalate dehydratase small subunit low > 80
Escherichia fergusonii Becca 0.96 EFB2_01546 Amidophosphoribosyltransferase 0.88 EFB2_03974 3-isopropylmalate dehydratase small subunit low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.96 OHPLBJKB_01393 Amidophosphoribosyltransferase 0.88 OHPLBJKB_03586 3-isopropylmalate dehydratase small subunit low > 73
Erwinia tracheiphila SCR3 0.92 LU632_RS07865 purF amidophosphoribosyltransferase 0.74 LU632_RS02865 leuD 3-isopropylmalate dehydratase small subunit 0.68 38
Pectobacterium carotovorum WPP14 0.91 HER17_RS07020 amidophosphoribosyltransferase 0.84 HER17_RS03070 3-isopropylmalate dehydratase small subunit 0.97 6
Serratia liquefaciens MT49 0.91 IAI46_17810 amidophosphoribosyltransferase 0.84 IAI46_03340 3-isopropylmalate dehydratase small subunit low > 86
Pantoea sp. MT58 0.90 IAI47_06275 amidophosphoribosyltransferase 0.83 IAI47_16015 3-isopropylmalate dehydratase small subunit 0.77 46
Dickeya dadantii 3937 0.89 DDA3937_RS14435 amidophosphoribosyltransferase 0.84 DDA3937_RS18130 3-isopropylmalate dehydratase small subunit 0.66 42
Rahnella sp. WP5 0.89 EX31_RS19570 amidophosphoribosyltransferase 0.84 EX31_RS03695 3-isopropylmalate dehydratase small subunit 0.91 41
Dickeya dianthicola 67-19 0.89 HGI48_RS14405 amidophosphoribosyltransferase 0.83 HGI48_RS18070 3-isopropylmalate dehydratase small subunit 0.75 15
Dickeya dianthicola ME23 0.89 DZA65_RS15335 amidophosphoribosyltransferase 0.84 DZA65_RS19215 3-isopropylmalate dehydratase small subunit 0.60 59
Vibrio cholerae E7946 ATCC 55056 0.77 CSW01_05115 amidophosphoribosyltransferase 0.73 CSW01_12610 3-isopropylmalate dehydratase small subunit low > 62
Shewanella amazonensis SB2B 0.75 Sama_2146 amidophosphoribosyltransferase (RefSeq) 0.60 Sama_0338 leuD isopropylmalate isomerase small subunit (RefSeq) 0.75 60
Shewanella loihica PV-4 0.74 Shew_2302 amidophosphoribosyltransferase (RefSeq) 0.63 Shew_3469 isopropylmalate isomerase small subunit (RefSeq) 0.80 33
Shewanella sp. ANA-3 0.74 Shewana3_1483 amidophosphoribosyltransferase (RefSeq) 0.59 Shewana3_3758 leuD isopropylmalate isomerase small subunit (RefSeq) 0.85 45
Shewanella oneidensis MR-1 0.74 SO3064 purF amidophosphoribosyltransferase (NCBI ptt file) 0.60 SO4233 leuD 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) 0.83 50
Alteromonas macleodii MIT1002 0.72 MIT1002_02524 Amidophosphoribosyltransferase 0.62 MIT1002_00946 3-isopropylmalate dehydratase small subunit 1 0.97 14
Kangiella aquimarina DSM 16071 0.64 B158DRAFT_1488 amidophosphoribosyltransferase (EC 2.4.2.14) 0.59 B158DRAFT_1320 3-isopropylmalate dehydratase, small subunit
Marinobacter adhaerens HP15 0.63 HP15_1821 amidophosphoribosyltransferase 0.55 HP15_1833 isopropylmalate isomerase small subunit
Pseudomonas sp. S08-1 0.63 OH686_04420 amidophosphoribosyltransferase 0.62 OH686_04475 3-isopropylmalate dehydratase small subunit
Pseudomonas sp. RS175 0.62 PFR28_02811 Amidophosphoribosyltransferase 0.62 PFR28_02823 3-isopropylmalate dehydratase small subunit 1 0.59 19
Pseudomonas putida KT2440 0.62 PP_2000 amidophosphoribosyl transferase 0.62 PP_1986 3-isopropylmalate dehydratase small subunit 0.31 41
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3935 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.62 PfGW456L13_3947 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
Acinetobacter radioresistens SK82 0.62 MPMX26_01122 Amidophosphoribosyltransferase 0.55 MPMX26_00346 3-isopropylmalate dehydratase small subunit 1 0.85 21
Pseudomonas stutzeri RCH2 0.62 Psest_2579 amidophosphoribosyltransferase 0.63 Psest_2590 3-isopropylmalate dehydratase, small subunit 0.59 30
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_21465 amidophosphoribosyltransferase 0.61 AO356_21405 3-isopropylmalate dehydratase 0.78 25
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_76 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.62 Pf6N2E2_64 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
Pseudomonas syringae pv. syringae B728a 0.61 Psyr_1668 amidophosphoribosyltransferase 0.61 Psyr_1984 3-isopropylmalate dehydratase, small subunit 0.77 18
Pseudomonas fluorescens FW300-N2E3 0.61 AO353_20690 amidophosphoribosyltransferase 0.62 AO353_20625 3-isopropylmalate dehydratase
Pseudomonas syringae pv. syringae B728a ΔmexB 0.61 Psyr_1668 amidophosphoribosyltransferase 0.61 Psyr_1984 3-isopropylmalate dehydratase, small subunit 0.88 6
Pseudomonas fluorescens SBW25 0.61 PFLU_RS20515 amidophosphoribosyltransferase 0.61 PFLU_RS20575 3-isopropylmalate dehydratase small subunit low > 109
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS20515 amidophosphoribosyltransferase 0.61 PFLU_RS20575 3-isopropylmalate dehydratase small subunit 0.60 8
Pseudomonas simiae WCS417 0.61 PS417_18535 amidophosphoribosyltransferase 0.61 PS417_18595 3-isopropylmalate dehydratase
Ralstonia sp. UNC404CL21Col 0.59 ABZR87_RS14465 amidophosphoribosyltransferase 0.60 ABZR87_RS14535 3-isopropylmalate dehydratase small subunit
Dyella japonica UNC79MFTsu3.2 0.59 ABZR86_RS06775 amidophosphoribosyltransferase 0.40 ABZR86_RS15955 3-isopropylmalate dehydratase small subunit 0.91 59
Rhodanobacter sp. FW510-T8 0.58 OKGIIK_05570 purF amidophosphoribosyltransferase 0.40 OKGIIK_13590 leuD 3-isopropylmalate dehydratase small subunit low > 52
Ralstonia solanacearum IBSBF1503 0.58 RALBFv3_RS02550 amidophosphoribosyltransferase 0.58 RALBFv3_RS02615 3-isopropylmalate dehydratase small subunit
Ralstonia solanacearum UW163 0.58 UW163_RS11175 amidophosphoribosyltransferase 0.58 UW163_RS11110 3-isopropylmalate dehydratase small subunit
Ralstonia solanacearum PSI07 0.58 RPSI07_RS14765 amidophosphoribosyltransferase 0.59 RPSI07_RS14700 3-isopropylmalate dehydratase small subunit
Ralstonia solanacearum GMI1000 0.58 RS_RS09930 amidophosphoribosyltransferase 0.59 RS_RS09995 3-isopropylmalate dehydratase small subunit
Rhodanobacter denitrificans FW104-10B01 0.58 LRK54_RS01340 amidophosphoribosyltransferase 0.45 LRK54_RS07370 3-isopropylmalate dehydratase small subunit low > 59
Rhodanobacter denitrificans MT42 0.58 LRK55_RS01105 amidophosphoribosyltransferase 0.45 LRK55_RS07100 3-isopropylmalate dehydratase small subunit low > 63
Xanthomonas campestris pv. campestris strain 8004 0.58 Xcc-8004.4073.1 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.61 Xcc-8004.1050.1 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.68 51
Lysobacter sp. OAE881 0.57 ABIE51_RS06180 amidophosphoribosyltransferase 0.42 ABIE51_RS17580 3-isopropylmalate dehydratase small subunit low > 62
Dechlorosoma suillum PS 0.57 Dsui_3186 amidophosphoribosyltransferase 0.56 Dsui_3199 3-isopropylmalate dehydratase, small subunit
Paraburkholderia graminis OAS925 0.56 ABIE53_004816 amidophosphoribosyltransferase 0.57 ABIE53_004803 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit
Burkholderia phytofirmans PsJN 0.56 BPHYT_RS33840 amidophosphoribosyltransferase 0.58 BPHYT_RS33905 3-isopropylmalate dehydratase small subunit 0.70 67
Paraburkholderia bryophila 376MFSha3.1 0.56 H281DRAFT_06060 amidophosphoribosyltransferase 0.59 H281DRAFT_06073 3-isopropylmalate dehydratase, small subunit low > 103
Herbaspirillum seropedicae SmR1 0.56 HSERO_RS16445 amidophosphoribosyltransferase 0.57 HSERO_RS16505 3-isopropylmalate dehydratase small subunit
Cupriavidus basilensis FW507-4G11 0.56 RR42_RS14325 amidophosphoribosyltransferase 0.59 RR42_RS14390 3-isopropylmalate dehydratase
Acidovorax sp. GW101-3H11 0.55 Ac3H11_2608 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.57 Ac3H11_1527 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.75 32
Castellaniella sp019104865 MT123 0.54 ABCV34_RS04130 amidophosphoribosyltransferase 0.55 ABCV34_RS04285 3-isopropylmalate dehydratase small subunit
Hydrogenophaga sp. GW460-11-11-14-LB1 0.54 GFF300 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.58 GFF3361 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
Paraburkholderia sabiae LMG 24235 0.53 QEN71_RS17680 amidophosphoribosyltransferase 0.58 QEN71_RS17615 3-isopropylmalate dehydratase small subunit 0.64 89
Variovorax sp. SCN45 0.53 GFF3089 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.60 GFF3889 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) low > 127
Variovorax sp. OAS795 0.53 ABID97_RS21635 amidophosphoribosyltransferase 0.58 ABID97_RS08460 3-isopropylmalate dehydratase small subunit
Caulobacter crescentus NA1000 0.32 CCNA_01730 amidophosphoribosyltransferase 0.42 CCNA_00195 3-isopropylmalate dehydratase small subunit 0.73 40
Caulobacter crescentus NA1000 Δfur 0.32 CCNA_01730 amidophosphoribosyltransferase 0.42 CCNA_00195 3-isopropylmalate dehydratase small subunit low > 67
Azospirillum brasilense Sp245 0.30 AZOBR_RS08310 amidophosphoribosyltransferase 0.50 AZOBR_RS14135 isopropylmalate isomerase 0.67 16
Synechococcus elongatus PCC 7942 0.30 Synpcc7942_0004 purF amidophosphoribosyltransferase 0.27 Synpcc7942_2548 leuD isopropylmalate isomerase small subunit
Rhodospirillum rubrum S1H 0.30 Rru_A0404 Amidophosphoribosyl transferase (NCBI) 0.50 Rru_A1190 3-isopropylmalate dehydratase small subunit region (NCBI) 0.57 50
Azospirillum sp. SherDot2 0.30 MPMX19_00906 Amidophosphoribosyltransferase 0.51 MPMX19_00606 3-isopropylmalate dehydratase small subunit 1 0.84 34
Bifidobacterium breve UCC2003 0.30 BBR_RS13380 amidophosphoribosyltransferase 0.43 BBR_RS19625 3-isopropylmalate dehydratase small subunit low > 34
Agrobacterium fabrum C58 0.29 Atu1075 amidophosphoribosyltransferase 0.49 Atu2790 3-isopropylmalate dehydratase, small subunit 0.89 23
Brevundimonas sp. GW460-12-10-14-LB2 0.29 A4249_RS03735 amidophosphoribosyltransferase 0.40 A4249_RS10000 3-isopropylmalate dehydratase small subunit
Phaeobacter inhibens DSM 17395 0.29 PGA1_c10810 amidophosphoribosyltransferase PurF 0.49 PGA1_c29790 3-isopropylmalate dehydratase small subunit 0.87 17
Bosea sp. OAE506 0.29 ABIE41_RS17810 amidophosphoribosyltransferase 0.47 ABIE41_RS11640 3-isopropylmalate dehydratase small subunit
Rhizobium sp. OAE497 0.29 ABIE40_RS06270 amidophosphoribosyltransferase 0.48 ABIE40_RS19040 3-isopropylmalate dehydratase small subunit 0.89 25
Sinorhizobium meliloti 1021 0.28 SMc00554 amidophosphoribosyltransferase 0.49 SMc03795 isopropylmalate isomerase small subunit 0.92 36
Sphingomonas koreensis DSMZ 15582 0.28 Ga0059261_3626 amidophosphoribosyltransferase (EC 2.4.2.14) 0.37 Ga0059261_4225 3-isopropylmalate dehydratase, small subunit
Magnetospirillum magneticum AMB-1 0.28 AMB_RS10545 amidophosphoribosyltransferase 0.51 AMB_RS20565 3-isopropylmalate dehydratase small subunit
Rhodopseudomonas palustris CGA009 0.28 TX73_015990 amidophosphoribosyltransferase 0.51 TX73_001215 3-isopropylmalate dehydratase small subunit
Dinoroseobacter shibae DFL-12 0.28 Dshi_2132 amidophosphoribosyltransferase (RefSeq) 0.51 Dshi_0083 3-isopropylmalate dehydratase, small subunit (RefSeq) 0.69 30
Mycobacterium tuberculosis H37Rv 0.27 Rv0808 Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) 0.39 Rv2987c Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI)
Bacteroides thetaiotaomicron VPI-5482 0.12 BT0555 amidophosphoribosyltransferase (NCBI ptt file) 0.39 BT1859 3-isopropylmalate dehydratase small subunit (NCBI ptt file) low > 81
Parabacteroides merdae CL09T00C40 0.11 HMPREF1078_RS10430 amidophosphoribosyltransferase 0.42 HMPREF1078_RS16655 3-isopropylmalate dehydratase small subunit low > 61
Pedobacter sp. GW460-11-11-14-LB5 0.11 CA265_RS15055 amidophosphoribosyltransferase 0.44 CA265_RS15840 3-isopropylmalate dehydratase small subunit
Mucilaginibacter yixingensis YX-36 DSM 26809 0.11 ABZR88_RS15630 class II glutamine amidotransferase 0.45 ABZR88_RS11600 3-isopropylmalate dehydratase small subunit

Not shown: 5 genomes with orthologs for BWI76_RS20350 only; 7 genomes with orthologs for BWI76_RS04665 only