Conservation of cofitness between BWI76_RS01615 and BWI76_RS04255 in Klebsiella michiganensis M5al

93 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS01615 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 1.0 BWI76_RS04255 threonine synthase 0.88 9
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF4186 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.89 GFF1080 Threonine synthase (EC 4.2.3.1) low > 78
Enterobacter asburiae PDN3 0.96 EX28DRAFT_4545 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) 0.92 EX28DRAFT_3616 threonine synthase — —
Enterobacter sp. TBS_079 0.96 MPMX20_00226 Bifunctional purine biosynthesis protein PurH 0.91 MPMX20_00712 Threonine synthase 0.86 21
Escherichia coli ECOR38 0.94 HEPCGN_11950 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.91 HEPCGN_09105 thrC threonine synthase 0.65 81
Escherichia fergusonii Becca 0.94 EFB2_04604 Bifunctional purine biosynthesis protein PurH 0.91 EFB2_04039 Threonine synthase low > 86
Escherichia coli ECRC99 0.94 KEDOAH_14850 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.91 KEDOAH_17055 thrC threonine synthase — —
Escherichia coli ECRC98 0.94 JDDGAC_16935 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.91 JDDGAC_14695 thrC threonine synthase low > 86
Escherichia coli ECRC100 0.94 OKFHMN_13310 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.91 OKFHMN_11100 thrC threonine synthase low > 80
Escherichia coli ECRC101 0.94 MCAODC_03810 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.91 MCAODC_01615 thrC threonine synthase low > 87
Escherichia coli ECRC102 0.94 NIAGMN_11060 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.91 NIAGMN_08950 thrC threonine synthase — —
Escherichia coli ECRC62 0.94 BNILDI_06065 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.91 BNILDI_08170 thrC threonine synthase low > 75
Escherichia coli ECOR27 0.94 NOLOHH_05455 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.91 NOLOHH_03430 thrC threonine synthase low > 75
Escherichia coli Nissle 1917 0.94 ECOLIN_RS23100 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.90 ECOLIN_RS00020 threonine synthase low > 55
Escherichia coli HS(pFamp)R (ATCC 700891) 0.94 OHPLBJKB_04043 Bifunctional purine biosynthesis protein PurH 0.91 OHPLBJKB_03656 Threonine synthase low > 73
Escherichia coli BL21 0.94 ECD_03883 IMP cyclohydrolase and phosphoribosylaminoimidazolecarboxamide formyltransferase 0.91 ECD_00004 L-threonine synthase 0.60 48
Escherichia coli BW25113 0.94 b4006 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) 0.91 b0004 thrC threonine synthase (NCBI) 0.84 23
Dickeya dadantii 3937 0.91 DDA3937_RS01220 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.81 DDA3937_RS18405 threonine synthase 0.81 18
Dickeya dianthicola 67-19 0.90 HGI48_RS01215 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.79 HGI48_RS18335 threonine synthase 0.70 29
Pantoea sp. MT58 0.90 IAI47_18040 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.81 IAI47_16205 threonine synthase 0.83 40
Pectobacterium carotovorum WPP14 0.90 HER17_RS20335 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.79 HER17_RS02805 threonine synthase 0.94 35
Dickeya dianthicola ME23 0.90 DZA65_RS01260 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.80 DZA65_RS19475 threonine synthase 0.72 25
Serratia liquefaciens MT49 0.89 IAI46_01365 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.85 IAI46_03040 threonine synthase 0.59 27
Erwinia tracheiphila SCR3 0.89 LU632_RS01020 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.81 LU632_RS02620 thrC threonine synthase — —
Rahnella sp. WP5 0.88 EX31_RS16860 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.84 EX31_RS03935 threonine synthase 0.95 20
Vibrio cholerae E7946 ATCC 55056 0.80 CSW01_01420 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 0.68 CSW01_11965 threonine synthase low > 62
Shewanella loihica PV-4 0.77 Shew_3412 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) 0.58 Shew_1081 threonine synthase (RefSeq) 0.77 44
Shewanella amazonensis SB2B 0.76 Sama_0395 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) 0.56 Sama_0907 threonine synthase (RefSeq) 0.88 35
Alteromonas macleodii MIT1002 0.75 MIT1002_03959 Bifunctional purine biosynthesis protein PurH 0.64 MIT1002_03084 Threonine synthase — —
Shewanella sp. ANA-3 0.74 Shewana3_0441 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) 0.57 Shewana3_1141 threonine synthase (RefSeq) 0.90 32
Shewanella oneidensis MR-1 0.73 SO0442 purH phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI ptt file) 0.56 SO3413 thrC threonine synthase (NCBI ptt file) 0.91 32
Marinobacter adhaerens HP15 0.71 HP15_3227 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.25 HP15_765 threonine synthase — —
Pseudomonas sp. S08-1 0.69 OH686_07620 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.26 OH686_17765 threonine synthase — —
Pseudomonas fluorescens FW300-N1B4 0.68 Pf1N1B4_1315 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.26 Pf1N1B4_3014 Threonine synthase (EC 4.2.3.1) — —
Pseudomonas fluorescens FW300-N2E3 0.68 AO353_13650 phosphoribosylaminoimidazolecarboxamide formyltransferase 0.26 AO353_04350 threonine synthase — —
Pseudomonas putida KT2440 0.68 PP_4822 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.27 PP_1471 Threonine synthase — —
Pseudomonas fluorescens FW300-N2E2 0.68 Pf6N2E2_3519 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.26 Pf6N2E2_3142 Threonine synthase (EC 4.2.3.1) — —
Pseudomonas stutzeri RCH2 0.68 Psest_1014 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.26 Psest_3125 threonine synthase — —
Pseudomonas sp. RS175 0.68 PFR28_05214 Bifunctional purine biosynthesis protein PurH 0.26 PFR28_00334 Threonine synthase — —
Pseudomonas fluorescens GW456-L13 0.68 PfGW456L13_57 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.26 PfGW456L13_1724 Threonine synthase (EC 4.2.3.1) — —
Pseudomonas fluorescens FW300-N2C3 0.68 AO356_08225 phosphoribosylaminoimidazolecarboxamide formyltransferase 0.26 AO356_06370 threonine synthase — —
Pseudomonas fluorescens SBW25-INTG 0.68 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.26 PFLU_RS24545 threonine synthase — —
Pseudomonas fluorescens SBW25 0.68 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.26 PFLU_RS24545 threonine synthase 0.88 6
Pseudomonas syringae pv. syringae B728a ΔmexB 0.68 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase 0.26 Psyr_1291 L-threonine synthase — —
Pseudomonas syringae pv. syringae B728a 0.68 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase 0.26 Psyr_1291 L-threonine synthase — —
Pseudomonas simiae WCS417 0.68 PS417_02940 phosphoribosylaminoimidazolecarboxamide formyltransferase 0.26 PS417_22880 threonine synthase — —
Dyella japonica UNC79MFTsu3.2 0.61 ABZR86_RS17045 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.28 ABZR86_RS15975 threonine synthase (EC 4.2.3.1) (from data) — —
Paraburkholderia bryophila 376MFSha3.1 0.60 H281DRAFT_04251 IMP cyclohydrolase /phosphoribosylaminoimidazolecarboxamide formyltransferase 0.22 H281DRAFT_00811 L-threonine synthase — —
Paraburkholderia graminis OAS925 0.60 ABIE53_003491 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.23 ABIE53_002027 threonine synthase — —
Burkholderia phytofirmans PsJN 0.60 BPHYT_RS16595 bifunctional purine biosynthesis protein PurH 0.22 BPHYT_RS08960 threonine synthase — —
Paraburkholderia sabiae LMG 24235 0.59 QEN71_RS26780 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.21 QEN71_RS22400 threonine synthase low > 153
Ralstonia solanacearum PSI07 0.59 RPSI07_RS21530 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.21 RPSI07_RS17485 threonine synthase — —
Ralstonia solanacearum UW163 0.59 UW163_RS01900 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.20 UW163_RS13325 threonine synthase — —
Ralstonia solanacearum IBSBF1503 0.59 RALBFv3_RS11685 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.20 RALBFv3_RS15880 threonine synthase — —
Cupriavidus basilensis FW507-4G11 0.59 RR42_RS02720 phosphoribosylaminoimidazolecarboxamide formyltransferase 0.21 RR42_RS12535 threonine synthase — —
Ralstonia solanacearum GMI1000 0.59 RS_RS02505 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 0.22 RS_RS06660 threonine synthase — —
Ralstonia sp. UNC404CL21Col 0.59 ABZR87_RS07640 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.23 ABZR87_RS05865 threonine synthase — —
Rhodanobacter denitrificans MT42 0.59 LRK55_RS06570 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.29 LRK55_RS09995 threonine synthase low > 63
Rhodanobacter denitrificans FW104-10B01 0.58 LRK54_RS06825 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.29 LRK54_RS10355 threonine synthase — —
Herbaspirillum seropedicae SmR1 0.58 HSERO_RS02060 purine biosynthesis protein purH 0.22 HSERO_RS10470 threonine synthase — —
Rhodanobacter sp. FW510-T8 0.58 OKGIIK_16805 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.28 OKGIIK_13570 thrC threonine synthase — —
Lysobacter sp. OAE881 0.57 ABIE51_RS17760 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.31 ABIE51_RS17530 threonine synthase low > 62
Xanthomonas campestris pv. campestris strain 8004 0.57 Xcc-8004.659.1 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.30 Xcc-8004.2954.1 Threonine synthase (EC 4.2.3.1) low > 74
Hydrogenophaga sp. GW460-11-11-14-LB1 0.57 GFF636 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.21 GFF3936 Threonine synthase (EC 4.2.3.1) — —
Variovorax sp. SCN45 0.56 GFF2146 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.22 GFF2800 Threonine synthase (EC 4.2.3.1) — —
Variovorax sp. OAS795 0.56 ABID97_RS24725 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.22 ABID97_RS25760 threonine synthase — —
Acidovorax sp. GW101-3H11 0.55 Ac3H11_3994 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.23 Ac3H11_1505 Threonine synthase (EC 4.2.3.1) — —
Castellaniella sp019104865 MT123 0.55 ABCV34_RS07970 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.24 ABCV34_RS02300 threonine synthase — —
Dechlorosoma suillum PS 0.54 Dsui_1595 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.21 Dsui_2904 threonine synthase — —
Azospirillum sp. SherDot2 0.54 MPMX19_02325 Bifunctional purine biosynthesis protein PurH 0.24 MPMX19_00671 Threonine synthase — —
Rhodopseudomonas palustris CGA009 0.52 TX73_000145 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.24 TX73_004325 threonine synthase — —
Bosea sp. OAE506 0.51 ABIE41_RS05095 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.28 ABIE41_RS22985 threonine synthase — —
Phaeobacter inhibens DSM 17395 0.51 PGA1_c32860 bifunctional purine biosynthesis protein PurH 0.26 PGA1_c06310 threonine synthase ThrC — —
Azospirillum brasilense Sp245 0.51 AZOBR_RS00225 purine biosynthesis protein purH 0.26 AZOBR_RS10545 threonine synthase — —
Sphingomonas koreensis DSMZ 15582 0.50 Ga0059261_2242 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.22 Ga0059261_1999 threonine synthase — —
Magnetospirillum magneticum AMB-1 0.50 AMB_RS00505 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.25 AMB_RS17140 threonine synthase — —
Rhodospirillum rubrum S1H 0.49 Rru_A3655 Phosphoribosylaminoimidazolecarboxamideformyltransferase (NCBI) 0.25 Rru_A3233 Threonine synthase (NCBI) — —
Dinoroseobacter shibae DFL-12 0.49 Dshi_0358 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) 0.26 Dshi_1146 threonine synthase (RefSeq) — —
Rhizobium sp. OAE497 0.47 ABIE40_RS19130 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.26 ABIE40_RS04230 threonine synthase — —
Sinorhizobium meliloti 1021 0.47 SMc04088 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.26 SMc00077 threonine synthase — —
Agrobacterium fabrum C58 0.47 Atu2823 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.26 Atu0787 threonine synthase — —
Caulobacter crescentus NA1000 Δfur 0.46 CCNA_00084 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.28 CCNA_03510 threonine synthase — —
Caulobacter crescentus NA1000 0.46 CCNA_00084 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.28 CCNA_03510 threonine synthase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.44 A4249_RS13150 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.23 A4249_RS00020 threonine synthase — —
Pedobacter sp. GW460-11-11-14-LB5 0.36 CA265_RS02705 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.40 CA265_RS23465 threonine synthase — —
Bacteroides ovatus ATCC 8483 0.35 BACOVA_03657 putative phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.42 BACOVA_03023 threonine synthase low > 94
Mucilaginibacter yixingensis YX-36 DSM 26809 0.35 ABZR88_RS16970 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.40 ABZR88_RS18960 threonine synthase — —
Bacteroides stercoris CC31F 0.35 HMPREF1181_RS00165 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.42 HMPREF1181_RS00050 threonine synthase 0.93 11
Bacteroides thetaiotaomicron VPI-5482 0.34 BT3812 phosphoribosylaminoimidazole carboxy formyl formyltransferase; inosine-monophosphate cyclohydrolase; bifunctional purine biosynthesis protein purH (NCBI ptt file) 0.42 BT2401 threonine synthase (NCBI ptt file) low > 81
Bifidobacterium breve UCC2003 0.34 BBR_RS15690 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.20 BBR_RS14070 threonine synthase — —
Phocaeicola vulgatus CL09T03C04 0.34 HMPREF1058_RS13605 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.42 HMPREF1058_RS14730 threonine synthase low > 67
Parabacteroides merdae CL09T00C40 0.34 HMPREF1078_RS16130 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.40 HMPREF1078_RS10395 threonine synthase low > 61
Phocaeicola dorei CL03T12C01 0.34 ABI39_RS09195 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.42 ABI39_RS10440 threonine synthase low > 72
Echinicola vietnamensis KMM 6221, DSM 17526 0.34 Echvi_1469 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) 0.40 Echvi_2002 threonine synthase — —

Not shown: 6 genomes with orthologs for BWI76_RS01615 only; 0 genomes with orthologs for BWI76_RS04255 only