Conservation of cofitness between BWI76_RS00805 and BWI76_RS04255 in Klebsiella michiganensis M5al

93 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 1.0 BWI76_RS04255 threonine synthase 0.91 6
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.89 GFF1080 Threonine synthase (EC 4.2.3.1) low > 78
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.92 EX28DRAFT_3616 threonine synthase low > 76
Enterobacter sp. TBS_079 0.95 MPMX20_04529 5,10-methylenetetrahydrofolate reductase 0.91 MPMX20_00712 Threonine synthase 0.74 18
Escherichia coli BL21 0.95 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.91 ECD_00004 L-threonine synthase 0.95 12
Escherichia coli ECOR27 0.95 NOLOHH_05810 metF methylenetetrahydrofolate reductase 0.91 NOLOHH_03430 thrC threonine synthase 0.98 7
Escherichia coli BW25113 0.95 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.91 b0004 thrC threonine synthase (NCBI) 0.93 31
Escherichia coli ECRC62 0.95 BNILDI_05725 metF methylenetetrahydrofolate reductase 0.91 BNILDI_08170 thrC threonine synthase 0.91 62
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase 0.91 OHPLBJKB_03656 Threonine synthase low > 73
Escherichia coli ECRC102 0.95 NIAGMN_11420 metF methylenetetrahydrofolate reductase 0.91 NIAGMN_08950 thrC threonine synthase
Escherichia coli ECRC101 0.95 MCAODC_04165 metF methylenetetrahydrofolate reductase 0.91 MCAODC_01615 thrC threonine synthase 0.87 45
Escherichia coli ECRC100 0.95 OKFHMN_13665 metF methylenetetrahydrofolate reductase 0.91 OKFHMN_11100 thrC threonine synthase 0.99 15
Escherichia coli ECOR38 0.95 HEPCGN_12310 metF methylenetetrahydrofolate reductase 0.91 HEPCGN_09105 thrC threonine synthase 0.82 69
Escherichia coli ECRC99 0.95 KEDOAH_14495 metF methylenetetrahydrofolate reductase 0.91 KEDOAH_17055 thrC threonine synthase
Escherichia coli ECRC98 0.95 JDDGAC_17290 metF methylenetetrahydrofolate reductase 0.91 JDDGAC_14695 thrC threonine synthase 0.88 41
Escherichia fergusonii Becca 0.94 EFB2_04672 5,10-methylenetetrahydrofolate reductase 0.91 EFB2_04039 Threonine synthase low > 86
Escherichia coli Nissle 1917 0.94 ECOLIN_RS22760 methylenetetrahydrofolate reductase 0.90 ECOLIN_RS00020 threonine synthase low > 55
Pantoea sp. MT58 0.92 IAI47_00890 methylenetetrahydrofolate reductase 0.81 IAI47_16205 threonine synthase 0.47 51
Serratia liquefaciens MT49 0.92 IAI46_24530 methylenetetrahydrofolate reductase 0.85 IAI46_03040 threonine synthase 0.84 7
Dickeya dadantii 3937 0.91 DDA3937_RS00960 methylenetetrahydrofolate reductase 0.81 DDA3937_RS18405 threonine synthase low > 74
Rahnella sp. WP5 0.91 EX31_RS14205 methylenetetrahydrofolate reductase 0.84 EX31_RS03935 threonine synthase 0.93 9
Pectobacterium carotovorum WPP14 0.90 HER17_RS00950 methylenetetrahydrofolate reductase 0.79 HER17_RS02805 threonine synthase low > 75
Dickeya dianthicola 67-19 0.90 HGI48_RS20415 methylenetetrahydrofolate reductase 0.79 HGI48_RS18335 threonine synthase low > 71
Dickeya dianthicola ME23 0.90 DZA65_RS21460 methylenetetrahydrofolate reductase 0.80 DZA65_RS19475 threonine synthase low > 75
Erwinia tracheiphila SCR3 0.87 LU632_RS19630 metF methylenetetrahydrofolate reductase 0.81 LU632_RS02620 thrC threonine synthase
Vibrio cholerae E7946 ATCC 55056 0.78 CSW01_13560 methylenetetrahydrofolate reductase 0.68 CSW01_11965 threonine synthase low > 62
Shewanella oneidensis MR-1 0.76 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.56 SO3413 thrC threonine synthase (NCBI ptt file) 0.95 25
Shewanella amazonensis SB2B 0.76 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.56 Sama_0907 threonine synthase (RefSeq) 0.96 22
Shewanella sp. ANA-3 0.76 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.57 Shewana3_1141 threonine synthase (RefSeq) 0.94 23
Shewanella loihica PV-4 0.75 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.58 Shew_1081 threonine synthase (RefSeq) 0.98 13
Alteromonas macleodii MIT1002 0.70 MIT1002_03670 5,10-methylenetetrahydrofolate reductase 0.64 MIT1002_03084 Threonine synthase low > 70
Azospirillum brasilense Sp245 0.55 AZOBR_RS09540 5 10-methylenetetrahydrofolate reductase 0.26 AZOBR_RS10545 threonine synthase
Magnetospirillum magneticum AMB-1 0.55 AMB_RS02230 methylenetetrahydrofolate reductase 0.25 AMB_RS17140 threonine synthase
Azospirillum sp. SherDot2 0.55 MPMX19_00635 5,10-methylenetetrahydrofolate reductase 0.24 MPMX19_00671 Threonine synthase
Sphingomonas koreensis DSMZ 15582 0.54 Ga0059261_0992 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.22 Ga0059261_1999 threonine synthase 0.63 55
Bosea sp. OAE506 0.52 ABIE41_RS12475 methylenetetrahydrofolate reductase [NAD(P)H] 0.28 ABIE41_RS22985 threonine synthase
Rhodospirillum rubrum S1H 0.52 Rru_A1530 5,10-methylenetetrahydrofolate reductase (NCBI) 0.25 Rru_A3233 Threonine synthase (NCBI)
Caulobacter crescentus NA1000 0.48 CCNA_02224 methylenetetrahydrofolate reductase 0.28 CCNA_03510 threonine synthase
Caulobacter crescentus NA1000 Δfur 0.48 CCNA_02224 methylenetetrahydrofolate reductase 0.28 CCNA_03510 threonine synthase
Rhodopseudomonas palustris CGA009 0.46 TX73_019175 methylenetetrahydrofolate reductase [NAD(P)H] 0.24 TX73_004325 threonine synthase
Brevundimonas sp. GW460-12-10-14-LB2 0.46 A4249_RS07925 methylenetetrahydrofolate reductase [NAD(P)H] 0.23 A4249_RS00020 threonine synthase 0.99 29
Rhizobium sp. OAE497 0.41 ABIE40_RS11950 methylenetetrahydrofolate reductase [NAD(P)H] 0.26 ABIE40_RS04230 threonine synthase
Paraburkholderia sabiae LMG 24235 0.41 QEN71_RS28715 methylenetetrahydrofolate reductase [NAD(P)H] 0.21 QEN71_RS22400 threonine synthase 0.83 48
Paraburkholderia bryophila 376MFSha3.1 0.40 H281DRAFT_05801 5,10-methylenetetrahydrofolate reductase (NAD(P)) 0.22 H281DRAFT_00811 L-threonine synthase
Paraburkholderia graminis OAS925 0.40 ABIE53_000061 methylenetetrahydrofolate reductase (NADPH) 0.23 ABIE53_002027 threonine synthase
Phaeobacter inhibens DSM 17395 0.40 PGA1_c11700 5,10-methylenetetrahydrofolate reductase MetF 0.26 PGA1_c06310 threonine synthase ThrC
Cupriavidus basilensis FW507-4G11 0.39 RR42_RS01385 5,10-methylenetetrahydrofolate reductase 0.21 RR42_RS12535 threonine synthase
Agrobacterium fabrum C58 0.39 Atu2123 methylenetetrahydrofolate reductase 0.26 Atu0787 threonine synthase
Burkholderia phytofirmans PsJN 0.39 BPHYT_RS18705 5,10-methylenetetrahydrofolate reductase 0.22 BPHYT_RS08960 threonine synthase 0.34 85
Dechlorosoma suillum PS 0.39 Dsui_0640 5,10-methylenetetrahydrofolate reductase 0.21 Dsui_2904 threonine synthase
Ralstonia solanacearum PSI07 0.38 RPSI07_RS23495 methylenetetrahydrofolate reductase [NAD(P)H] 0.21 RPSI07_RS17485 threonine synthase
Ralstonia sp. UNC404CL21Col 0.38 ABZR87_RS04865 methylenetetrahydrofolate reductase [NAD(P)H] 0.23 ABZR87_RS05865 threonine synthase low > 80
Ralstonia solanacearum GMI1000 0.38 RS_RS00460 methylenetetrahydrofolate reductase [NAD(P)H] 0.22 RS_RS06660 threonine synthase
Ralstonia solanacearum UW163 0.38 UW163_RS03705 methylenetetrahydrofolate reductase [NAD(P)H] 0.20 UW163_RS13325 threonine synthase
Ralstonia solanacearum IBSBF1503 0.38 RALBFv3_RS09875 methylenetetrahydrofolate reductase [NAD(P)H] 0.20 RALBFv3_RS15880 threonine synthase
Pseudomonas sp. RS175 0.38 PFR28_04202 5,10-methylenetetrahydrofolate reductase 0.26 PFR28_00334 Threonine synthase
Pseudomonas sp. S08-1 0.37 OH686_10820 methylenetetrahydrofolate reductase [NAD(P)H] 0.26 OH686_17765 threonine synthase low > 80
Dinoroseobacter shibae DFL-12 0.37 Dshi_2080 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.26 Dshi_1146 threonine synthase (RefSeq)
Xanthomonas campestris pv. campestris strain 8004 0.37 Xcc-8004.4336.1 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.30 Xcc-8004.2954.1 Threonine synthase (EC 4.2.3.1) low > 74
Pseudomonas simiae WCS417 0.37 PS417_26510 5,10-methylenetetrahydrofolate reductase 0.26 PS417_22880 threonine synthase
Sinorhizobium meliloti 1021 0.37 SMc01843 5,10-methylenetetrahydrofolate reductase 0.26 SMc00077 threonine synthase
Marinobacter adhaerens HP15 0.37 HP15_2917 5,10-methylenetetrahydrofolate reductase-like protein 0.25 HP15_765 threonine synthase
Pseudomonas fluorescens SBW25 0.37 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H] 0.26 PFLU_RS24545 threonine synthase low > 109
Pseudomonas fluorescens FW300-N2E2 0.37 Pf6N2E2_4638 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.26 Pf6N2E2_3142 Threonine synthase (EC 4.2.3.1)
Pseudomonas fluorescens SBW25-INTG 0.37 PFLU_RS28165 methylenetetrahydrofolate reductase [NAD(P)H] 0.26 PFLU_RS24545 threonine synthase
Pseudomonas fluorescens FW300-N1B4 0.37 Pf1N1B4_2384 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.26 Pf1N1B4_3014 Threonine synthase (EC 4.2.3.1)
Rhodanobacter denitrificans MT42 0.37 LRK55_RS11765 methylenetetrahydrofolate reductase [NAD(P)H] 0.29 LRK55_RS09995 threonine synthase low > 63
Rhodanobacter denitrificans FW104-10B01 0.37 LRK54_RS12030 methylenetetrahydrofolate reductase [NAD(P)H] 0.29 LRK54_RS10355 threonine synthase low > 59
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_13605 5,10-methylenetetrahydrofolate reductase 0.26 AO356_06370 threonine synthase
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_08015 5,10-methylenetetrahydrofolate reductase 0.26 AO353_04350 threonine synthase
Rhodanobacter sp. FW510-T8 0.36 OKGIIK_11830 metF methylenetetrahydrofolate reductase [NAD(P)H] 0.28 OKGIIK_13570 thrC threonine synthase low > 52
Herbaspirillum seropedicae SmR1 0.36 HSERO_RS21425 5,10-methylenetetrahydrofolate reductase 0.22 HSERO_RS10470 threonine synthase
Pseudomonas fluorescens GW456-L13 0.36 PfGW456L13_1050 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.26 PfGW456L13_1724 Threonine synthase (EC 4.2.3.1)
Pseudomonas putida KT2440 0.36 PP_4977 5,10-methylenetetrahydrofolate reductase 0.27 PP_1471 Threonine synthase
Pseudomonas stutzeri RCH2 0.36 Psest_0313 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.26 Psest_3125 threonine synthase
Dyella japonica UNC79MFTsu3.2 0.36 ABZR86_RS11570 methylenetetrahydrofolate reductase [NAD(P)H] 0.28 ABZR86_RS15975 threonine synthase (EC 4.2.3.1) (from data) 0.96 12
Pseudomonas syringae pv. syringae B728a 0.36 Psyr_0459 5,10-methylenetetrahydrofolate reductase 0.26 Psyr_1291 L-threonine synthase
Pseudomonas syringae pv. syringae B728a ΔmexB 0.36 Psyr_0459 5,10-methylenetetrahydrofolate reductase 0.26 Psyr_1291 L-threonine synthase
Lysobacter sp. OAE881 0.35 ABIE51_RS16490 methylenetetrahydrofolate reductase [NAD(P)H] 0.31 ABIE51_RS17530 threonine synthase 0.97 26
Castellaniella sp019104865 MT123 0.35 ABCV34_RS13550 methylenetetrahydrofolate reductase [NAD(P)H] 0.24 ABCV34_RS02300 threonine synthase
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF1692 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.21 GFF3936 Threonine synthase (EC 4.2.3.1)
Acidovorax sp. GW101-3H11 0.34 Ac3H11_3045 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.23 Ac3H11_1505 Threonine synthase (EC 4.2.3.1)
Variovorax sp. OAS795 0.33 ABID97_RS25015 methylenetetrahydrofolate reductase [NAD(P)H] 0.22 ABID97_RS25760 threonine synthase
Variovorax sp. SCN45 0.32 GFF2055 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.22 GFF2800 Threonine synthase (EC 4.2.3.1)
Bifidobacterium breve UCC2003 0.23 BBR_RS15410 methylenetetrahydrofolate reductase [NAD(P)H] 0.20 BBR_RS14070 threonine synthase low > 34
Mucilaginibacter yixingensis YX-36 DSM 26809 0.22 ABZR88_RS20935 methylenetetrahydrofolate reductase [NAD(P)H] 0.40 ABZR88_RS18960 threonine synthase
Parabacteroides merdae CL09T00C40 0.21 HMPREF1078_RS07860 methylenetetrahydrofolate reductase [NAD(P)H] 0.40 HMPREF1078_RS10395 threonine synthase low > 61
Echinicola vietnamensis KMM 6221, DSM 17526 0.21 Echvi_3637 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.40 Echvi_2002 threonine synthase 0.94 7
Pedobacter sp. GW460-11-11-14-LB5 0.21 CA265_RS23445 methylenetetrahydrofolate reductase [NAD(P)H] 0.40 CA265_RS23465 threonine synthase 0.87 53
Bacteroides thetaiotaomicron VPI-5482 0.20 BT3821 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.42 BT2401 threonine synthase (NCBI ptt file) low > 81
Phocaeicola dorei CL03T12C01 0.19 ABI39_RS15570 methylenetetrahydrofolate reductase [NAD(P)H] 0.42 ABI39_RS10440 threonine synthase low > 72
Phocaeicola vulgatus CL09T03C04 0.19 HMPREF1058_RS01490 methylenetetrahydrofolate reductase [NAD(P)H] 0.42 HMPREF1058_RS14730 threonine synthase low > 67
Bacteroides stercoris CC31F 0.18 HMPREF1181_RS00120 methylenetetrahydrofolate reductase [NAD(P)H] 0.42 HMPREF1181_RS00050 threonine synthase low > 56
Bacteroides ovatus ATCC 8483 0.16 BACOVA_03666 methylenetetrahydrofolate reductase (NAD(P)H) 0.42 BACOVA_03023 threonine synthase low > 94

Not shown: 6 genomes with orthologs for BWI76_RS00805 only; 0 genomes with orthologs for BWI76_RS04255 only