Conservation of cofitness between BWI76_RS20350 and BWI76_RS01615 in Klebsiella michiganensis M5al

92 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS20350 amidophosphoribosyltransferase 1.0 BWI76_RS01615 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 0.92 3
Enterobacter sp. TBS_079 0.98 MPMX20_03247 Amidophosphoribosyltransferase 0.96 MPMX20_00226 Bifunctional purine biosynthesis protein PurH 0.95 5
Enterobacter asburiae PDN3 0.98 EX28DRAFT_0292 amidophosphoribosyltransferase (EC 2.4.2.14) 0.96 EX28DRAFT_4545 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.98 GFF1927 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.97 GFF4186 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) 0.37 46
Escherichia coli BL21 0.97 ECD_02237 amidophosphoribosyltransferase 0.94 ECD_03883 IMP cyclohydrolase and phosphoribosylaminoimidazolecarboxamide formyltransferase 0.89 3
Escherichia coli ECOR27 0.97 NOLOHH_14335 purF amidophosphoribosyltransferase 0.94 NOLOHH_05455 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.94 6
Escherichia coli BW25113 0.97 b2312 purF amidophosphoribosyltransferase (NCBI) 0.94 b4006 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) 0.98 3
Escherichia coli ECRC62 0.97 BNILDI_13255 purF amidophosphoribosyltransferase 0.94 BNILDI_06065 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.98 4
Escherichia coli ECRC99 0.96 KEDOAH_05480 purF amidophosphoribosyltransferase 0.94 KEDOAH_14850 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Escherichia coli ECRC98 0.96 JDDGAC_26675 purF amidophosphoribosyltransferase 0.94 JDDGAC_16935 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.76 6
Escherichia fergusonii Becca 0.96 EFB2_01546 Amidophosphoribosyltransferase 0.94 EFB2_04604 Bifunctional purine biosynthesis protein PurH low > 86
Escherichia coli ECRC102 0.96 NIAGMN_20485 purF amidophosphoribosyltransferase 0.94 NIAGMN_11060 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Escherichia coli ECRC101 0.96 MCAODC_13755 purF amidophosphoribosyltransferase 0.94 MCAODC_03810 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.95 5
Escherichia coli Nissle 1917 0.96 ECOLIN_RS13405 amidophosphoribosyltransferase 0.94 ECOLIN_RS23100 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Escherichia coli ECOR38 0.96 HEPCGN_21910 purF amidophosphoribosyltransferase 0.94 HEPCGN_11950 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.98 4
Escherichia coli ECRC100 0.96 OKFHMN_22715 purF amidophosphoribosyltransferase 0.94 OKFHMN_13310 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.98 2
Escherichia coli HS(pFamp)R (ATCC 700891) 0.96 OHPLBJKB_01393 Amidophosphoribosyltransferase 0.94 OHPLBJKB_04043 Bifunctional purine biosynthesis protein PurH low > 73
Erwinia tracheiphila SCR3 0.92 LU632_RS07865 purF amidophosphoribosyltransferase 0.89 LU632_RS01020 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.74 21
Pectobacterium carotovorum WPP14 0.91 HER17_RS07020 amidophosphoribosyltransferase 0.90 HER17_RS20335 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.98 2
Serratia liquefaciens MT49 0.91 IAI46_17810 amidophosphoribosyltransferase 0.89 IAI46_01365 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.54 16
Pantoea sp. MT58 0.90 IAI47_06275 amidophosphoribosyltransferase 0.90 IAI47_18040 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.98 4
Dickeya dadantii 3937 0.89 DDA3937_RS14435 amidophosphoribosyltransferase 0.91 DDA3937_RS01220 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.90 6
Rahnella sp. WP5 0.89 EX31_RS19570 amidophosphoribosyltransferase 0.88 EX31_RS16860 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.97 3
Dickeya dianthicola 67-19 0.89 HGI48_RS14405 amidophosphoribosyltransferase 0.90 HGI48_RS01215 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.71 21
Dickeya dianthicola ME23 0.89 DZA65_RS15335 amidophosphoribosyltransferase 0.90 DZA65_RS01260 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.90 5
Vibrio cholerae E7946 ATCC 55056 0.77 CSW01_05115 amidophosphoribosyltransferase 0.80 CSW01_01420 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase low > 62
Shewanella amazonensis SB2B 0.75 Sama_2146 amidophosphoribosyltransferase (RefSeq) 0.76 Sama_0395 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) 0.89 7
Shewanella loihica PV-4 0.74 Shew_2302 amidophosphoribosyltransferase (RefSeq) 0.77 Shew_3412 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) 0.96 4
Shewanella sp. ANA-3 0.74 Shewana3_1483 amidophosphoribosyltransferase (RefSeq) 0.74 Shewana3_0441 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) 0.95 4
Shewanella oneidensis MR-1 0.74 SO3064 purF amidophosphoribosyltransferase (NCBI ptt file) 0.73 SO0442 purH phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI ptt file) 0.95 5
Alteromonas macleodii MIT1002 0.72 MIT1002_02524 Amidophosphoribosyltransferase 0.75 MIT1002_03959 Bifunctional purine biosynthesis protein PurH — —
Kangiella aquimarina DSM 16071 0.64 B158DRAFT_1488 amidophosphoribosyltransferase (EC 2.4.2.14) 0.70 B158DRAFT_0166 IMP cyclohydrolase (EC 3.5.4.10)/phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Marinobacter adhaerens HP15 0.63 HP15_1821 amidophosphoribosyltransferase 0.71 HP15_3227 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas sp. S08-1 0.63 OH686_04420 amidophosphoribosyltransferase 0.69 OH686_07620 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas putida KT2440 0.62 PP_2000 amidophosphoribosyl transferase 0.68 PP_4822 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas sp. RS175 0.62 PFR28_02811 Amidophosphoribosyltransferase 0.68 PFR28_05214 Bifunctional purine biosynthesis protein PurH — —
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3935 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.68 PfGW456L13_57 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Acinetobacter radioresistens SK82 0.62 MPMX26_01122 Amidophosphoribosyltransferase 0.70 MPMX26_01141 Bifunctional purine biosynthesis protein PurH 0.93 7
Pseudomonas stutzeri RCH2 0.62 Psest_2579 amidophosphoribosyltransferase 0.68 Psest_1014 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_21465 amidophosphoribosyltransferase 0.68 AO356_08225 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_76 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.68 Pf6N2E2_3519 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Pseudomonas syringae pv. syringae B728a 0.61 Psyr_1668 amidophosphoribosyltransferase 0.68 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.61 Psyr_1668 amidophosphoribosyltransferase 0.68 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas fluorescens FW300-N2E3 0.61 AO353_20690 amidophosphoribosyltransferase 0.68 AO353_13650 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas fluorescens SBW25 0.61 PFLU_RS20515 amidophosphoribosyltransferase 0.68 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH 0.94 1
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS20515 amidophosphoribosyltransferase 0.68 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Pseudomonas simiae WCS417 0.61 PS417_18535 amidophosphoribosyltransferase 0.68 PS417_02940 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Ralstonia sp. UNC404CL21Col 0.59 ABZR87_RS14465 amidophosphoribosyltransferase 0.59 ABZR87_RS07640 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Dyella japonica UNC79MFTsu3.2 0.59 ABZR86_RS06775 amidophosphoribosyltransferase 0.61 ABZR86_RS17045 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Rhodanobacter sp. FW510-T8 0.58 OKGIIK_05570 purF amidophosphoribosyltransferase 0.58 OKGIIK_16805 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Ralstonia solanacearum IBSBF1503 0.58 RALBFv3_RS02550 amidophosphoribosyltransferase 0.59 RALBFv3_RS11685 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Ralstonia solanacearum UW163 0.58 UW163_RS11175 amidophosphoribosyltransferase 0.59 UW163_RS01900 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Ralstonia solanacearum PSI07 0.58 RPSI07_RS14765 amidophosphoribosyltransferase 0.59 RPSI07_RS21530 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Ralstonia solanacearum GMI1000 0.58 RS_RS09930 amidophosphoribosyltransferase 0.59 RS_RS02505 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase — —
Rhodanobacter denitrificans MT42 0.58 LRK55_RS01105 amidophosphoribosyltransferase 0.59 LRK55_RS06570 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 63
Rhodanobacter denitrificans FW104-10B01 0.58 LRK54_RS01340 amidophosphoribosyltransferase 0.58 LRK54_RS06825 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Xanthomonas campestris pv. campestris strain 8004 0.58 Xcc-8004.4073.1 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.57 Xcc-8004.659.1 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) low > 74
Lysobacter sp. OAE881 0.57 ABIE51_RS06180 amidophosphoribosyltransferase 0.57 ABIE51_RS17760 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.83 14
Dechlorosoma suillum PS 0.57 Dsui_3186 amidophosphoribosyltransferase 0.54 Dsui_1595 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Burkholderia phytofirmans PsJN 0.56 BPHYT_RS33840 amidophosphoribosyltransferase 0.60 BPHYT_RS16595 bifunctional purine biosynthesis protein PurH — —
Paraburkholderia graminis OAS925 0.56 ABIE53_004816 amidophosphoribosyltransferase 0.60 ABIE53_003491 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Paraburkholderia bryophila 376MFSha3.1 0.56 H281DRAFT_06060 amidophosphoribosyltransferase 0.60 H281DRAFT_04251 IMP cyclohydrolase /phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Herbaspirillum seropedicae SmR1 0.56 HSERO_RS16445 amidophosphoribosyltransferase 0.58 HSERO_RS02060 purine biosynthesis protein purH — —
Cupriavidus basilensis FW507-4G11 0.56 RR42_RS14325 amidophosphoribosyltransferase 0.59 RR42_RS02720 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Acidovorax sp. GW101-3H11 0.55 Ac3H11_2608 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.55 Ac3H11_3994 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Castellaniella sp019104865 MT123 0.54 ABCV34_RS04130 amidophosphoribosyltransferase 0.55 ABCV34_RS07970 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.54 GFF300 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.57 GFF636 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Paraburkholderia sabiae LMG 24235 0.53 QEN71_RS17680 amidophosphoribosyltransferase 0.59 QEN71_RS26780 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 153
Variovorax sp. SCN45 0.53 GFF3089 Amidophosphoribosyltransferase (EC 2.4.2.14) 0.56 GFF2146 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Variovorax sp. OAS795 0.53 ABID97_RS21635 amidophosphoribosyltransferase 0.56 ABID97_RS24725 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Caulobacter crescentus NA1000 Δfur 0.32 CCNA_01730 amidophosphoribosyltransferase 0.46 CCNA_00084 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 67
Caulobacter crescentus NA1000 0.32 CCNA_01730 amidophosphoribosyltransferase 0.46 CCNA_00084 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.90 4
Azospirillum brasilense Sp245 0.30 AZOBR_RS08310 amidophosphoribosyltransferase 0.51 AZOBR_RS00225 purine biosynthesis protein purH — —
Synechococcus elongatus PCC 7942 0.30 Synpcc7942_0004 purF amidophosphoribosyltransferase 0.42 Synpcc7942_0396 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Rhodospirillum rubrum S1H 0.30 Rru_A0404 Amidophosphoribosyl transferase (NCBI) 0.49 Rru_A3655 Phosphoribosylaminoimidazolecarboxamideformyltransferase (NCBI) — —
Azospirillum sp. SherDot2 0.30 MPMX19_00906 Amidophosphoribosyltransferase 0.54 MPMX19_02325 Bifunctional purine biosynthesis protein PurH — —
Bifidobacterium breve UCC2003 0.30 BBR_RS13380 amidophosphoribosyltransferase 0.34 BBR_RS15690 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Phaeobacter inhibens DSM 17395 0.29 PGA1_c10810 amidophosphoribosyltransferase PurF 0.51 PGA1_c32860 bifunctional purine biosynthesis protein PurH — —
Brevundimonas sp. GW460-12-10-14-LB2 0.29 A4249_RS03735 amidophosphoribosyltransferase 0.44 A4249_RS13150 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Agrobacterium fabrum C58 0.29 Atu1075 amidophosphoribosyltransferase 0.47 Atu2823 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Bosea sp. OAE506 0.29 ABIE41_RS17810 amidophosphoribosyltransferase 0.51 ABIE41_RS05095 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 77
Rhizobium sp. OAE497 0.29 ABIE40_RS06270 amidophosphoribosyltransferase 0.47 ABIE40_RS19130 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.91 9
Sinorhizobium meliloti 1021 0.28 SMc00554 amidophosphoribosyltransferase 0.47 SMc04088 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.98 3
Sphingomonas koreensis DSMZ 15582 0.28 Ga0059261_3626 amidophosphoribosyltransferase (EC 2.4.2.14) 0.50 Ga0059261_2242 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Magnetospirillum magneticum AMB-1 0.28 AMB_RS10545 amidophosphoribosyltransferase 0.50 AMB_RS00505 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Rhodopseudomonas palustris CGA009 0.28 TX73_015990 amidophosphoribosyltransferase 0.52 TX73_000145 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Dinoroseobacter shibae DFL-12 0.28 Dshi_2132 amidophosphoribosyltransferase (RefSeq) 0.49 Dshi_0358 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) — —
Mycobacterium tuberculosis H37Rv 0.27 Rv0808 Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) 0.39 Rv0957 Probable bifunctional purine biosynthesis protein PurH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) (5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase) + inosinemonophosphate cyclohydrolase (imp cyclohydrolase) (inosinicase) (imp synthetase) (ATIC) — —
Fusobacterium nucleatum SB010 0.25 HUW76_05170 amidophosphoribosyltransferase 0.42 HUW76_05195 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 0.99 4
Bacteroides thetaiotaomicron VPI-5482 0.12 BT0555 amidophosphoribosyltransferase (NCBI ptt file) 0.34 BT3812 phosphoribosylaminoimidazole carboxy formyl formyltransferase; inosine-monophosphate cyclohydrolase; bifunctional purine biosynthesis protein purH (NCBI ptt file) low > 81
Parabacteroides merdae CL09T00C40 0.11 HMPREF1078_RS10430 amidophosphoribosyltransferase 0.34 HMPREF1078_RS16130 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 61
Pedobacter sp. GW460-11-11-14-LB5 0.11 CA265_RS15055 amidophosphoribosyltransferase 0.36 CA265_RS02705 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.11 ABZR88_RS15630 class II glutamine amidotransferase 0.35 ABZR88_RS16970 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —

Not shown: 4 genomes with orthologs for BWI76_RS20350 only; 7 genomes with orthologs for BWI76_RS01615 only