Conservation of cofitness between BPHYT_RS33915 and BPHYT_RS17395 in Burkholderia phytofirmans PsJN

93 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Burkholderia phytofirmans PsJN 1.0 BPHYT_RS33915 isopropylmalate isomerase 1.0 BPHYT_RS17395 anthranilate synthase subunit II 0.89 20
Paraburkholderia bryophila 376MFSha3.1 0.97 H281DRAFT_06075 3-isopropylmalate dehydratase, large subunit 0.95 H281DRAFT_05714 anthranilate synthase, component II 0.47 39
Paraburkholderia graminis OAS925 0.96 ABIE53_004801 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit 0.95 ABIE53_003641 anthranilate synthase component 2
Paraburkholderia sabiae LMG 24235 0.95 QEN71_RS17605 3-isopropylmalate dehydratase large subunit 0.93 QEN71_RS27555 aminodeoxychorismate/anthranilate synthase component II 0.66 63
Ralstonia solanacearum PSI07 0.87 RPSI07_RS14695 3-isopropylmalate dehydratase large subunit 0.78 RPSI07_RS10750 type 1 glutamine amidotransferase
Ralstonia sp. UNC404CL21Col 0.87 ABZR87_RS14540 3-isopropylmalate dehydratase large subunit 0.76 ABZR87_RS02145 aminodeoxychorismate/anthranilate synthase component II 0.80 29
Ralstonia solanacearum UW163 0.87 UW163_RS11105 3-isopropylmalate dehydratase large subunit 0.78 UW163_RS07135 type 1 glutamine amidotransferase
Ralstonia solanacearum IBSBF1503 0.87 RALBFv3_RS02620 3-isopropylmalate dehydratase large subunit 0.78 RALBFv3_RS06490 type 1 glutamine amidotransferase low > 76
Ralstonia solanacearum GMI1000 0.87 RS_RS10000 3-isopropylmalate dehydratase large subunit 0.77 RS_RS14435 type 1 glutamine amidotransferase
Cupriavidus basilensis FW507-4G11 0.86 RR42_RS14400 isopropylmalate isomerase 0.76 RR42_RS18300 anthranilate synthase subunit II 0.71 30
Herbaspirillum seropedicae SmR1 0.80 HSERO_RS16515 isopropylmalate isomerase 0.73 HSERO_RS19440 anthranilate synthase subunit II
Castellaniella sp019104865 MT123 0.77 ABCV34_RS04290 3-isopropylmalate dehydratase large subunit 0.65 ABCV34_RS10300 aminodeoxychorismate/anthranilate synthase component II low > 48
Variovorax sp. OAS795 0.75 ABID97_RS08465 3-isopropylmalate dehydratase large subunit 0.61 ABID97_RS05260 aminodeoxychorismate/anthranilate synthase component II
Hydrogenophaga sp. GW460-11-11-14-LB1 0.75 GFF3363 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.65 GFF3107 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.81 15
Variovorax sp. SCN45 0.75 GFF3890 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.63 GFF5894 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85)
Acidovorax sp. GW101-3H11 0.74 Ac3H11_1525 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.65 Ac3H11_769 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.89 22
Marinobacter adhaerens HP15 0.73 HP15_1834 protein containing 3-isopropylmalate dehydratase, large subunit region domain 0.61 HP15_3289 para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II 0.73 34
Pseudomonas fluorescens FW300-N2C3 0.73 AO356_21400 isopropylmalate isomerase 0.63 AO356_14430 anthranilate synthase 0.84 35
Pseudomonas sp. RS175 0.73 PFR28_02824 3-isopropylmalate dehydratase large subunit 0.63 PFR28_04045 Anthranilate synthase component 2
Pseudomonas fluorescens FW300-N2E3 0.72 AO353_20620 isopropylmalate isomerase 0.62 AO353_07220 anthranilate synthase 0.90 17
Pseudomonas fluorescens FW300-N2E2 0.72 Pf6N2E2_63 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.63 Pf6N2E2_4824 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.67 36
Xanthomonas campestris pv. campestris strain 8004 0.72 Xcc-8004.1049.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.59 Xcc-8004.618.1 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.87 19
Pseudomonas fluorescens GW456-L13 0.72 PfGW456L13_3948 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.63 PfGW456L13_1220 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.82 45
Pseudomonas stutzeri RCH2 0.72 Psest_2591 3-isopropylmalate dehydratase, large subunit 0.62 Psest_3649 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 0.77 27
Pseudomonas syringae pv. syringae B728a 0.72 Psyr_1983 3-isopropylmalate dehydratase, large subunit 0.63 Psyr_4581 anthranilate synthase, component II 0.73 35
Pseudomonas syringae pv. syringae B728a ΔmexB 0.72 Psyr_1983 3-isopropylmalate dehydratase, large subunit 0.63 Psyr_4581 anthranilate synthase, component II
Pseudomonas fluorescens FW300-N1B4 0.72 Pf1N1B4_15 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.63 Pf1N1B4_2547 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) 0.82 31
Pseudomonas simiae WCS417 0.72 PS417_18600 isopropylmalate isomerase 0.62 PS417_25720 anthranilate synthase component II 0.86 16
Pseudomonas putida KT2440 0.72 PP_1985 3-isopropylmalate dehydratase large subunit 0.62 PP_0420 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex 0.83 23
Pseudomonas fluorescens SBW25 0.71 PFLU_RS20580 3-isopropylmalate dehydratase large subunit 0.61 PFLU_RS27375 aminodeoxychorismate/anthranilate synthase component II low > 109
Pseudomonas fluorescens SBW25-INTG 0.71 PFLU_RS20580 3-isopropylmalate dehydratase large subunit 0.61 PFLU_RS27375 aminodeoxychorismate/anthranilate synthase component II 0.25 69
Pseudomonas sp. S08-1 0.71 OH686_04480 3-isopropylmalate dehydratase large subunit 0.63 OH686_15130 Anthranilate synthase, amidotransferase component or Para-aminobenzoate synthase, amidotransferase component
Dechlorosoma suillum PS 0.70 Dsui_3201 3-isopropylmalate dehydratase, large subunit 0.70 Dsui_0170 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase
Rhodospirillum rubrum S1H 0.69 Rru_A1189 3-isopropylmalate dehydratase large subunit region (NCBI) 0.53 Rru_A1895 Glutamine amidotransferase of anthranilate synthase (NCBI) 0.79 34
Acinetobacter radioresistens SK82 0.68 MPMX26_00345 3-isopropylmalate dehydratase large subunit 0.61 MPMX26_00985 Anthranilate synthase component 2 0.94 11
Azospirillum sp. SherDot2 0.68 MPMX19_01998 3-isopropylmalate dehydratase large subunit 0.56 MPMX19_01016 Anthranilate synthase component 2
Azospirillum brasilense Sp245 0.68 AZOBR_RS03545 isopropylmalate isomerase 0.54 AZOBR_RS07460 anthranilate synthase
Bosea sp. OAE506 0.66 ABIE41_RS11660 3-isopropylmalate dehydratase large subunit 0.48 ABIE41_RS17415 aminodeoxychorismate/anthranilate synthase component II
Magnetospirillum magneticum AMB-1 0.64 AMB_RS20560 3-isopropylmalate dehydratase large subunit 0.60 AMB_RS14405 type 1 glutamine amidotransferase
Pantoea sp. MT58 0.62 IAI47_16010 3-isopropylmalate dehydratase large subunit 0.57 IAI47_01950 aminodeoxychorismate/anthranilate synthase component II low > 76
Enterobacter asburiae PDN3 0.62 EX28DRAFT_3668 3-isopropylmalate dehydratase, large subunit 0.57 EX28DRAFT_4169 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase low > 76
Escherichia fergusonii Becca 0.62 EFB2_03973 3-isopropylmalate dehydratase large subunit 0.59 EFB2_00462 Aminodeoxychorismate synthase component 2 low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.62 GFF166 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.59 GFF3709 Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) low > 78
Escherichia coli BW25113 0.62 b0072 leuC isopropylmalate isomerase large subunit (NCBI) 0.59 b3360 pabA para-aminobenzoate synthase component II (NCBI) low > 76
Escherichia coli ECOR38 0.62 HEPCGN_08705 leuC1 3-isopropylmalate dehydratase large subunit 1 0.58 HEPCGN_16050 pabA aminodeoxychorismate synthase component 2 low > 87
Escherichia coli ECRC62 0.62 BNILDI_08540 leuC1 3-isopropylmalate dehydratase large subunit 1 0.59 BNILDI_02500 pabA aminodeoxychorismate synthase component 2 low > 75
Escherichia coli ECOR27 0.62 NOLOHH_03070 leuC1 3-isopropylmalate dehydratase large subunit 1 0.59 NOLOHH_09020 pabA aminodeoxychorismate synthase component 2 low > 75
Escherichia coli BL21 0.62 ECD_00074 3-isopropylmalate dehydratase large subunit 0.59 ECD_03211 aminodeoxychorismate synthase, subunit II low > 61
Escherichia coli Nissle 1917 0.62 ECOLIN_RS00390 3-isopropylmalate dehydratase large subunit 0.59 ECOLIN_RS19245 aminodeoxychorismate synthase component 2 low > 55
Rahnella sp. WP5 0.62 EX31_RS03690 3-isopropylmalate dehydratase large subunit 0.55 EX31_RS04635 aminodeoxychorismate synthase component II low > 89
Escherichia coli HS(pFamp)R (ATCC 700891) 0.62 OHPLBJKB_03585 3-isopropylmalate dehydratase large subunit 0.59 OHPLBJKB_00342 Aminodeoxychorismate synthase component 2 low > 73
Caulobacter crescentus NA1000 Δfur 0.62 CCNA_00196 3-isopropylmalate dehydratase large subunit 0.57 CCNA_01974 anthranilate synthase component II/para-aminobenzoate synthase glutamine amidotransferase component II low > 67
Caulobacter crescentus NA1000 0.62 CCNA_00196 3-isopropylmalate dehydratase large subunit 0.57 CCNA_01974 anthranilate synthase component II/para-aminobenzoate synthase glutamine amidotransferase component II 0.90 41
Dickeya dianthicola ME23 0.62 DZA65_RS19210 3-isopropylmalate dehydratase large subunit 0.59 DZA65_RS20660 aminodeoxychorismate synthase component II low > 75
Dickeya dianthicola 67-19 0.62 HGI48_RS18065 3-isopropylmalate dehydratase large subunit 0.59 HGI48_RS19575 aminodeoxychorismate synthase component II
Escherichia coli ECRC99 0.61 KEDOAH_17430 leuC1 3-isopropylmalate dehydratase large subunit 1 0.59 KEDOAH_10920 pabA aminodeoxychorismate synthase component 2
Escherichia coli ECRC100 0.61 OKFHMN_10725 leuC1 3-isopropylmalate dehydratase large subunit 1 0.59 OKFHMN_17220 pabA aminodeoxychorismate synthase component 2 low > 80
Escherichia coli ECRC101 0.61 MCAODC_01240 leuC1 3-isopropylmalate dehydratase large subunit 1 0.59 MCAODC_07750 pabA aminodeoxychorismate synthase component 2 low > 87
Escherichia coli ECRC102 0.61 NIAGMN_08575 leuC1 3-isopropylmalate dehydratase large subunit 1 0.59 NIAGMN_14990 pabA aminodeoxychorismate synthase component 2
Escherichia coli ECRC98 0.61 JDDGAC_14320 leuC1 3-isopropylmalate dehydratase large subunit 1 0.59 JDDGAC_20850 pabA aminodeoxychorismate synthase component 2 low > 86
Klebsiella michiganensis M5al 0.61 BWI76_RS04670 3-isopropylmalate dehydratase large subunit 0.57 BWI76_RS26005 glutamine amidotransferase low > 92
Enterobacter sp. TBS_079 0.61 MPMX20_00767 3-isopropylmalate dehydratase large subunit 1 0.57 MPMX20_04263 Aminodeoxychorismate synthase component 2 low > 85
Dickeya dadantii 3937 0.61 DDA3937_RS18125 3-isopropylmalate dehydratase large subunit 0.60 DDA3937_RS19455 aminodeoxychorismate synthase component II
Pectobacterium carotovorum WPP14 0.61 HER17_RS03075 3-isopropylmalate dehydratase large subunit 0.60 HER17_RS01905 aminodeoxychorismate synthase component II low > 75
Rhodanobacter denitrificans FW104-10B01 0.60 LRK54_RS07375 3-isopropylmalate dehydratase large subunit 0.62 LRK54_RS11560 aminodeoxychorismate/anthranilate synthase component II low > 59
Rhodanobacter denitrificans MT42 0.60 LRK55_RS07105 3-isopropylmalate dehydratase large subunit 0.62 LRK55_RS11290 aminodeoxychorismate/anthranilate synthase component II low > 63
Phaeobacter inhibens DSM 17395 0.59 PGA1_c29780 3-isopropylmalate dehydratase large subunit 0.56 PGA1_c16880 anthranilate synthase component II
Vibrio cholerae E7946 ATCC 55056 0.59 CSW01_12605 3-isopropylmalate dehydratase large subunit 0.57 CSW01_13255 aminodeoxychorismate/anthranilate synthase component II low > 62
Serratia liquefaciens MT49 0.59 IAI46_03345 3-isopropylmalate dehydratase large subunit 0.59 IAI46_23595 aminodeoxychorismate synthase component II low > 86
Shewanella loihica PV-4 0.59 Shew_3470 isopropylmalate isomerase large subunit (RefSeq) 0.53 Shew_0575 glutamine amidotransferase of anthranilate synthase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.59 SO4234 leuC 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) 0.51 SO0613 pabA para-aminobenzoate synthase glutamine amidotransferase, component II (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.59 Shewana3_3759 isopropylmalate isomerase large subunit (RefSeq) 0.52 Shewana3_0606 aminodeoxychorismate synthase, glutamine amidotransferase subunit (RefSeq) low > 73
Erwinia tracheiphila SCR3 0.58 LU632_RS02870 leuC 3-isopropylmalate dehydratase large subunit 0.56 LU632_RS22815 aminodeoxychorismate synthase component II
Shewanella amazonensis SB2B 0.58 Sama_0337 isopropylmalate isomerase large subunit (RefSeq) 0.50 Sama_3015 para-aminobenzoate synthase glutamine amidotransferase, component II (RefSeq) low > 62
Dinoroseobacter shibae DFL-12 0.58 Dshi_0085 3-isopropylmalate dehydratase, large subunit (RefSeq) 0.56 Dshi_1798 glutamine amidotransferase of anthranilate synthase (RefSeq)
Sphingomonas koreensis DSMZ 15582 0.58 Ga0059261_4223 3-isopropylmalate dehydratase, large subunit 0.47 Ga0059261_0926 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 0.94 41
Mycobacterium tuberculosis H37Rv 0.57 Rv2988c Probable 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) 0.43 Rv0013 Possible anthranilate synthase component II TrpG (glutamine amidotransferase)
Alteromonas macleodii MIT1002 0.57 MIT1002_00947 3-isopropylmalate dehydratase large subunit 0.52 MIT1002_00439 Para-aminobenzoate synthase glutamine amidotransferase component II low > 70
Bifidobacterium breve UCC2003 0.54 BBR_RS19630 3-isopropylmalate dehydratase large subunit 0.37 BBR_RS10595 glutamine amidotransferase low > 34
Mucilaginibacter yixingensis YX-36 DSM 26809 0.52 ABZR88_RS11595 3-isopropylmalate dehydratase large subunit 0.41 ABZR88_RS16600 aminodeoxychorismate/anthranilate synthase component II
Pontibacter actiniarum KMM 6156, DSM 19842 0.51 CA264_09435 3-isopropylmalate dehydratase large subunit 0.43 CA264_05060 glutamine amidotransferase low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.51 CA265_RS15830 3-isopropylmalate dehydratase large subunit 0.41 CA265_RS22895 aminodeoxychorismate/anthranilate synthase component II 0.69 70
Bacteroides thetaiotaomicron VPI-5482 0.50 BT1860 3-isopropylmalate dehydratase large subunit (NCBI ptt file) 0.43 BT0531 anthranilate synthase component II (NCBI ptt file) 0.73 52
Bacteroides stercoris CC31F 0.50 HMPREF1181_RS14145 3-isopropylmalate dehydratase large subunit 0.45 HMPREF1181_RS15330 aminodeoxychorismate/anthranilate synthase component II 0.85 50
Phocaeicola dorei CL03T12C01 0.50 ABI39_RS10200 3-isopropylmalate dehydratase large subunit 0.42 ABI39_RS21055 aminodeoxychorismate/anthranilate synthase component II low > 72
Bacteroides ovatus ATCC 8483 0.50 BACOVA_04603 3-isopropylmalate dehydratase, large subunit 0.43 BACOVA_03781 glutamine amidotransferase, class I 0.86 63
Phocaeicola vulgatus CL09T03C04 0.49 HMPREF1058_RS14550 3-isopropylmalate dehydratase large subunit 0.43 HMPREF1058_RS07180 aminodeoxychorismate/anthranilate synthase component II 0.80 25
Echinicola vietnamensis KMM 6221, DSM 17526 0.49 Echvi_2059 3-isopropylmalate dehydratase, large subunit 0.42 Echvi_2506 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 0.60 44
Parabacteroides merdae CL09T00C40 0.49 HMPREF1078_RS16660 3-isopropylmalate dehydratase large subunit 0.42 HMPREF1078_RS00140 aminodeoxychorismate/anthranilate synthase component II low > 61
Dyella japonica UNC79MFTsu3.2 0.49 ABZR86_RS15960 3-isopropylmalate dehydratase large subunit 0.62 ABZR86_RS12075 aminodeoxychorismate/anthranilate synthase component II
Lysobacter sp. OAE881 0.48 ABIE51_RS17575 3-isopropylmalate dehydratase large subunit 0.61 ABIE51_RS04175 aminodeoxychorismate/anthranilate synthase component II low > 62
Synechococcus elongatus PCC 7942 0.47 Synpcc7942_1898 leuC isopropylmalate isomerase large subunit 0.52 Synpcc7942_0400 trpG anthranilate synthase, component II
Rhodanobacter sp. FW510-T8 0.47 OKGIIK_13585 leuC 3-isopropylmalate dehydratase large subunit 0.63 OKGIIK_12290 pabA anthranilate/aminodeoxychorismate synthase component II low > 52
Brevundimonas sp. GW460-12-10-14-LB2 0.46 A4249_RS10005 3-isopropylmalate dehydratase large subunit 0.57 A4249_RS06165 aminodeoxychorismate/anthranilate synthase component II low > 48

Not shown: 5 genomes with orthologs for BPHYT_RS33915 only; 5 genomes with orthologs for BPHYT_RS17395 only