Conservation of cofitness between Atu1308 and Atu0486 in Agrobacterium fabrum C58

96 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu1308 aspartate carbamoyl transferase catalytic subunit 1.0 Atu0486 dihydroorotate dehydrogenase 0.93 3
Sinorhizobium meliloti 1021 0.91 SMc01360 aspartate carbamoyltransferase catalytic subunit 0.73 SMc02245 dihydroorotate dehydrogenase 2 0.88 4
Rhizobium sp. OAE497 0.89 ABIE40_RS07385 aspartate carbamoyltransferase catalytic subunit 0.72 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase — —
Bosea sp. OAE506 0.75 ABIE41_RS17230 aspartate carbamoyltransferase catalytic subunit 0.41 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase 0.77 2
Rhodopseudomonas palustris CGA009 0.68 TX73_016120 aspartate carbamoyltransferase catalytic subunit 0.45 TX73_004110 quinone-dependent dihydroorotate dehydrogenase — —
Rhodospirillum rubrum S1H 0.67 Rru_A3190 Aspartate carbamoyltransferase (NCBI) 0.41 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) 0.70 3
Magnetospirillum magneticum AMB-1 0.67 AMB_RS18300 aspartate carbamoyltransferase 0.42 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase — —
Azospirillum sp. SherDot2 0.67 MPMX19_01054 Aspartate carbamoyltransferase 0.45 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) — —
Azospirillum brasilense Sp245 0.66 AZOBR_RS20575 aspartate carbamoyltransferase 0.45 AZOBR_RS13520 dihydroorotate dehydrogenase 0.67 2
Phaeobacter inhibens DSM 17395 0.65 PGA1_c03060 aspartate carbamoyltransferase PyrB 0.45 PGA1_c12150 dihydroorotate dehydrogenase PyrD 0.95 3
Dinoroseobacter shibae DFL-12 0.64 Dshi_3091 aspartate carbamoyltransferase (RefSeq) 0.42 Dshi_0847 Dihydroorotate oxidase (RefSeq) 0.88 4
Sphingomonas koreensis DSMZ 15582 0.61 Ga0059261_0076 aspartate carbamoyltransferase (EC 2.1.3.2) 0.42 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) — —
Caulobacter crescentus NA1000 0.61 CCNA_02525 aspartate carbamoyltransferase 0.41 CCNA_00562 dihydroorotate dehydrogenase 0.95 5
Caulobacter crescentus NA1000 Δfur 0.61 CCNA_02525 aspartate carbamoyltransferase 0.41 CCNA_00562 dihydroorotate dehydrogenase 0.61 29
Brevundimonas sp. GW460-12-10-14-LB2 0.60 A4249_RS04260 aspartate carbamoyltransferase catalytic subunit 0.41 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.53 RALBFv3_RS12625 aspartate carbamoyltransferase catalytic subunit 0.38 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase — —
Cupriavidus basilensis FW507-4G11 0.53 RR42_RS15860 aspartate carbamoyltransferase catalytic subunit 0.37 RR42_RS07465 dihydroorotate dehydrogenase — —
Ralstonia solanacearum UW163 0.53 UW163_RS00940 aspartate carbamoyltransferase catalytic subunit 0.38 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum PSI07 0.53 RPSI07_RS20635 aspartate carbamoyltransferase catalytic subunit 0.37 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia sp. UNC404CL21Col 0.53 ABZR87_RS08625 aspartate carbamoyltransferase catalytic subunit 0.37 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum GMI1000 0.53 RS_RS03410 aspartate carbamoyltransferase 0.37 RS_RS08160 dihydroorotate dehydrogenase (quinone) — —
Paraburkholderia sabiae LMG 24235 0.52 QEN71_RS25780 aspartate carbamoyltransferase catalytic subunit 0.40 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas stutzeri RCH2 0.52 Psest_0291 aspartate carbamoyltransferase 0.39 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 — —
Paraburkholderia bryophila 376MFSha3.1 0.52 H281DRAFT_04817 aspartate carbamoyltransferase 0.38 H281DRAFT_00743 dihydroorotate oxidase A — —
Paraburkholderia graminis OAS925 0.52 ABIE53_001131 aspartate carbamoyltransferase catalytic subunit 0.39 ABIE53_001954 dihydroorotate dehydrogenase — —
Pseudomonas sp. S08-1 0.52 OH686_10940 aspartate carbamoyltransferase 0.38 OH686_03120 dihydroorotate dehydrogenase (fumarate) — —
Burkholderia phytofirmans PsJN 0.52 BPHYT_RS04235 aspartate carbamoyltransferase 0.39 BPHYT_RS08565 dihydroorotate dehydrogenase 0.30 11
Marinobacter adhaerens HP15 0.52 HP15_3507 aspartate carbamoyltransferase 0.38 HP15_1377 dihydroorotate dehydrogenase 0.75 6
Dechlorosoma suillum PS 0.51 Dsui_0596 aspartate carbamoyltransferase 0.39 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 — —
Variovorax sp. SCN45 0.51 GFF2160 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.39 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) — —
Acidovorax sp. GW101-3H11 0.51 Ac3H11_3978 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.41 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens FW300-N2E3 0.51 AO353_08135 aspartate carbamoyltransferase catalytic subunit 0.39 AO353_00780 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas simiae WCS417 0.51 PS417_26700 aspartate carbamoyltransferase catalytic subunit 0.39 PS417_20935 dihydroorotate dehydrogenase — —
Pseudomonas fluorescens GW456-L13 0.51 PfGW456L13_1016 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.38 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens FW300-N2E2 0.51 Pf6N2E2_4606 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.38 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens FW300-N2C3 0.51 AO356_13450 aspartate carbamoyltransferase catalytic subunit 0.38 AO356_02610 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas fluorescens SBW25 0.51 PFLU_RS28345 aspartate carbamoyltransferase 0.39 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.51 PFLU_RS28345 aspartate carbamoyltransferase 0.39 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens FW300-N1B4 0.51 Pf1N1B4_2347 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.38 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.51 Psyr_0482 aspartate carbamoyltransferase 0.38 Psyr_2106 dihydroorotate oxidase A — —
Desulfovibrio vulgaris Hildenborough JW710 0.51 DVU2901 pyrB aspartate carbamoyltransferase (TIGR) 0.08 DVU3316 pyrD dihydroorotate dehydrogenase (TIGR) — —
Pseudomonas sp. RS175 0.51 PFR28_04237 Aspartate carbamoyltransferase 0.38 PFR28_01054 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas syringae pv. syringae B728a 0.51 Psyr_0482 aspartate carbamoyltransferase 0.38 Psyr_2106 dihydroorotate oxidase A — —
Variovorax sp. OAS795 0.50 ABID97_RS24660 aspartate carbamoyltransferase catalytic subunit 0.40 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.50 GFF651 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.40 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.97 2
Pseudomonas putida KT2440 0.50 PP_4998 Aspartate carbamoyltransferase 0.39 PP_2095 Dihydroorotate dehydrogenase (quinone) — —
Herbaspirillum seropedicae SmR1 0.50 HSERO_RS02330 aspartate carbamoyltransferase 0.38 HSERO_RS16155 dihydroorotate dehydrogenase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.49 Echvi_4661 aspartate carbamoyltransferase 0.39 Echvi_1806 dihydroorotate dehydrogenase, subfamily 2 — —
Pedobacter sp. GW460-11-11-14-LB5 0.48 CA265_RS14660 aspartate carbamoyltransferase 0.38 CA265_RS14005 dihydroorotate dehydrogenase (quinone) — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.47 CA264_20465 aspartate carbamoyltransferase 0.40 CA264_00865 dihydroorotate dehydrogenase (quinone) low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.47 ABZR88_RS03460 aspartate carbamoyltransferase catalytic subunit 0.39 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase — —
Desulfovibrio vulgaris Miyazaki F 0.47 DvMF_1425 pyrB aspartate carbamoyltransferase catalytic subunit (RefSeq) 0.07 DvMF_2143 dihydroorotate dehydrogenase family protein (RefSeq) 0.91 5
Mycobacterium tuberculosis H37Rv 0.46 Rv1380 Probable aspartate carbamoyltransferase PyrB (ATCase) (aspartate transcarbamylase) 0.33 Rv2139 Probable dihydroorotate dehydrogenase PyrD — —
Acinetobacter radioresistens SK82 0.46 MPMX26_01099 Aspartate carbamoyltransferase 0.40 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) 0.97 2
Rhodanobacter sp. FW510-T8 0.43 OKGIIK_11095 pyrB aspartate carbamoyltransferase catalytic subunit 0.39 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Dyella japonica UNC79MFTsu3.2 0.42 ABZR86_RS10390 aspartate carbamoyltransferase catalytic subunit 0.40 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.42 LRK54_RS04220 aspartate carbamoyltransferase catalytic subunit 0.38 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans MT42 0.42 LRK55_RS03990 aspartate carbamoyltransferase catalytic subunit 0.38 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.42 Xcc-8004.1722.1 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.36 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Lysobacter sp. OAE881 0.41 ABIE51_RS16015 aspartate carbamoyltransferase catalytic subunit 0.36 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase — —
Fusobacterium nucleatum SB010 0.31 HUW76_08765 aspartate carbamoyltransferase catalytic subunit 0.08 HUW76_08740 dihydroorotate dehydrogenase 0.97 17
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.23 GFF930 Aspartate carbamoyltransferase (EC 2.1.3.2) 0.38 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.58 9
Escherichia coli ECOR38 0.23 HEPCGN_10060 pyrB aspartate carbamoyltransferase 0.38 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase low > 85
Escherichia coli ECRC98 0.23 JDDGAC_15505 pyrB aspartate carbamoyltransferase 0.37 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC101 0.23 OKFHMN_11865 pyrB aspartate carbamoyltransferase 0.37 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli Nissle 1917 0.23 ECOLIN_RS24625 aspartate carbamoyltransferase 0.38 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli BW25113 0.23 b4245 pyrB aspartate carbamoyltransferase catalytic subunit (NCBI) 0.37 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 0.94 1
Escherichia coli ECRC102 0.23 NIAGMN_09715 pyrB aspartate carbamoyltransferase 0.37 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC62 0.23 BNILDI_07385 pyrB aspartate carbamoyltransferase 0.37 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli BL21 0.23 ECD_04113 aspartate carbamoyltransferase, catalytic subunit 0.37 ECD_00949 dihydro-orotate oxidase, FMN-linked 0.76 8
Escherichia coli ECOR27 0.23 NOLOHH_04125 pyrB aspartate carbamoyltransferase 0.37 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase low > 57
Escherichia coli ECRC101 0.23 MCAODC_02370 pyrB aspartate carbamoyltransferase 0.37 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia fergusonii Becca 0.23 EFB2_04288 Aspartate carbamoyltransferase catalytic subunit 0.38 EFB2_03126 Dihydroorotate dehydrogenase (quinone) low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.23 OHPLBJKB_03789 Aspartate carbamoyltransferase catalytic subunit 0.37 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) 0.75 6
Escherichia coli ECRC99 0.23 KEDOAH_16290 pyrB aspartate carbamoyltransferase 0.37 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Enterobacter asburiae PDN3 0.22 EX28DRAFT_3446 aspartate carbamoyltransferase (EC 2.1.3.2) 0.37 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) — —
Enterobacter sp. TBS_079 0.22 MPMX20_00544 Aspartate carbamoyltransferase catalytic subunit 0.37 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.96 1
Klebsiella michiganensis M5al 0.22 BWI76_RS02995 aspartate carbamoyltransferase 0.38 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.92 1
Pantoea sp. MT58 0.22 IAI47_16860 aspartate carbamoyltransferase 0.40 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.98 4
Serratia liquefaciens MT49 0.22 IAI46_02275 aspartate carbamoyltransferase 0.38 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.81 9
Parabacteroides merdae CL09T00C40 0.22 HMPREF1078_RS01350 aspartate carbamoyltransferase 0.08 HMPREF1078_RS02295 dihydroorotate dehydrogenase — —
Dickeya dadantii 3937 0.22 DDA3937_RS01925 aspartate carbamoyltransferase 0.39 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.91 3
Erwinia tracheiphila SCR3 0.22 LU632_RS20950 pyrB aspartate carbamoyltransferase 0.36 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.96 3
Dickeya dianthicola ME23 0.22 DZA65_RS01970 aspartate carbamoyltransferase 0.39 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.95 2
Vibrio cholerae E7946 ATCC 55056 0.21 CSW01_12725 aspartate carbamoyltransferase 0.39 CSW01_07490 dihydroorotate dehydrogenase (quinone) 0.68 17
Dickeya dianthicola 67-19 0.21 HGI48_RS01900 aspartate carbamoyltransferase 0.38 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.87 1
Pectobacterium carotovorum WPP14 0.21 HER17_RS19510 aspartate carbamoyltransferase 0.39 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.97 16
Phocaeicola dorei CL03T12C01 0.21 ABI39_RS17400 aspartate carbamoyltransferase 0.08 ABI39_RS17250 dihydroorotate dehydrogenase — —
Phocaeicola vulgatus CL09T03C04 0.21 HMPREF1058_RS03820 aspartate carbamoyltransferase 0.08 HMPREF1058_RS03975 dihydroorotate dehydrogenase — —
Alteromonas macleodii MIT1002 0.21 MIT1002_00423 Aspartate carbamoyltransferase catalytic chain 0.39 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) 0.87 40
Rahnella sp. WP5 0.21 EX31_RS12785 aspartate carbamoyltransferase 0.38 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.94 6
Bacteroides ovatus ATCC 8483 0.21 BACOVA_02450 aspartate carbamoyltransferase 0.08 BACOVA_02614 dihydroorotate dehydrogenase 1B — —
Shewanella oneidensis MR-1 0.20 SO1301 pyrB aspartate carbamoyltransferase (NCBI ptt file) 0.38 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) 0.95 2
Kangiella aquimarina DSM 16071 0.20 B158DRAFT_0021 aspartate carbamoyltransferase (EC 2.1.3.2) 0.36 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) — —
Shewanella sp. ANA-3 0.20 Shewana3_3070 aspartate carbamoyltransferase (RefSeq) 0.39 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.96 1
Shewanella loihica PV-4 0.20 Shew_1013 aspartate carbamoyltransferase (RefSeq) 0.39 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) 0.90 6
Shewanella amazonensis SB2B 0.19 Sama_0840 aspartate carbamoyltransferase (RefSeq) 0.38 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) 0.89 3

Not shown: 6 genomes with orthologs for Atu1308 only; 1 genomes with orthologs for Atu0486 only