Conservation of cofitness between b4177 and b0750 in Escherichia coli BW25113

93 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b4177 purA adenylosuccinate synthetase (NCBI) 1.0 b0750 nadA quinolinate synthetase (NCBI) 0.48 20
Escherichia coli ECRC98 1.00 JDDGAC_15870 purA adenylosuccinate synthase 0.99 JDDGAC_10415 nadA quinolinate synthase NadA — —
Escherichia coli ECRC101 1.00 MCAODC_02745 purA adenylosuccinate synthase 0.99 MCAODC_25980 nadA quinolinate synthase NadA — —
Escherichia coli ECOR38 1.00 HEPCGN_10460 purA adenylosuccinate synthase 0.99 HEPCGN_01515 nadA quinolinate synthase NadA low > 85
Escherichia coli ECRC102 1.00 NIAGMN_10080 purA adenylosuccinate synthase 0.99 NIAGMN_04810 nadA quinolinate synthase NadA — —
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03865 Adenylosuccinate synthetase 0.99 OHPLBJKB_02963 Quinolinate synthase A low > 73
Escherichia coli BL21 1.00 ECD_04044 adenylosuccinate synthetase 1.00 ECD_00703 quinolinate synthase, subunit A — —
Escherichia coli ECRC101 1.00 OKFHMN_12230 purA adenylosuccinate synthase 0.99 OKFHMN_06760 nadA quinolinate synthase NadA — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS24255 adenylosuccinate synthase 0.99 ECOLIN_RS03990 quinolinate synthase NadA low > 52
Escherichia coli ECRC99 1.00 KEDOAH_15925 purA adenylosuccinate synthase 0.99 KEDOAH_21205 nadA quinolinate synthase NadA — —
Escherichia coli ECRC62 1.00 BNILDI_06995 purA adenylosuccinate synthase 1.00 BNILDI_21185 nadA quinolinate synthase NadA — —
Escherichia coli ECOR27 1.00 NOLOHH_04495 purA adenylosuccinate synthase 1.00 NOLOHH_23190 nadA quinolinate synthase NadA — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 1.00 GFF830 Adenylosuccinate synthetase (EC 6.3.4.4) 0.90 GFF4 Quinolinate synthetase (EC 2.5.1.72) — —
Escherichia fergusonii Becca 1.00 EFB2_04358 Adenylosuccinate synthetase 0.99 EFB2_03356 Quinolinate synthase A low > 86
Enterobacter sp. TBS_079 0.97 MPMX20_00458 Adenylosuccinate synthetase 0.89 MPMX20_01377 Quinolinate synthase A — —
Klebsiella michiganensis M5al 0.97 BWI76_RS02565 adenylosuccinate synthase 0.90 BWI76_RS08580 quinolinate synthetase — —
Enterobacter asburiae PDN3 0.96 EX28DRAFT_3374 Adenylosuccinate synthetase (EC 6.3.4.4) 0.90 EX28DRAFT_2245 quinolinate synthetase (EC 2.5.1.72) — —
Serratia liquefaciens MT49 0.91 IAI46_01650 adenylosuccinate synthase 0.86 IAI46_06380 quinolinate synthase NadA — —
Pectobacterium carotovorum WPP14 0.91 HER17_RS02610 adenylosuccinate synthase 0.85 HER17_RS14820 quinolinate synthase NadA — —
Rahnella sp. WP5 0.90 EX31_RS08795 adenylosuccinate synthase 0.83 EX31_RS23525 quinolinate synthase NadA — —
Dickeya dianthicola ME23 0.89 DZA65_RS19655 adenylosuccinate synthase 0.81 DZA65_RS06945 quinolinate synthase NadA low > 75
Pantoea sp. MT58 0.89 IAI47_02615 adenylosuccinate synthase 0.87 IAI47_13635 quinolinate synthase NadA — —
Dickeya dianthicola 67-19 0.89 HGI48_RS18520 adenylosuccinate synthase 0.81 HGI48_RS06595 quinolinate synthase NadA low > 71
Dickeya dadantii 3937 0.88 DDA3937_RS18585 adenylosuccinate synthase 0.81 DDA3937_RS06545 quinolinate synthase NadA low > 74
Vibrio cholerae E7946 ATCC 55056 0.78 CSW01_13175 adenylosuccinate synthetase 0.74 CSW01_09180 quinolinate synthase — —
Shewanella sp. ANA-3 0.78 Shewana3_0695 adenylosuccinate synthetase (RefSeq) 0.74 Shewana3_2128 quinolinate synthetase (RefSeq) — —
Shewanella oneidensis MR-1 0.78 SO3937 purA adenylosuccinate synthetase (NCBI ptt file) 0.75 SO2342 nadA quinolinate synthetase complex, subunit A (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.77 Shew_3291 adenylosuccinate synthetase (RefSeq) 0.75 Shew_1928 quinolinate synthetase (RefSeq) — —
Shewanella amazonensis SB2B 0.76 Sama_3069 adenylosuccinate synthetase (RefSeq) 0.74 Sama_1712 quinolinate synthetase (RefSeq) — —
Alteromonas macleodii MIT1002 0.75 MIT1002_00533 Adenylosuccinate synthetase 0.71 MIT1002_01344 Quinolinate synthase A — —
Pseudomonas putida KT2440 0.72 PP_4889 Adenylosuccinate synthetase 0.67 PP_1231 quinolinate synthase [4Fe-4S] cluster subunit — —
Pseudomonas fluorescens FW300-N1B4 0.72 Pf1N1B4_1407 Adenylosuccinate synthetase (EC 6.3.4.4) 0.66 Pf1N1B4_626 Quinolinate synthetase (EC 2.5.1.72) — —
Pseudomonas sp. S08-1 0.72 OH686_09440 adenylosuccinate synthase 0.66 OH686_19190 quinolinate synthetase complex, A subunit — —
Pseudomonas fluorescens FW300-N2E3 0.72 AO353_13170 adenylosuccinate synthetase 0.65 AO353_03525 quinolinate synthase A — —
Pseudomonas sp. RS175 0.71 PFR28_05126 Adenylosuccinate synthetase 0.66 PFR28_03388 Quinolinate synthase A — —
Pseudomonas fluorescens FW300-N2C3 0.71 AO356_08630 adenylosuccinate synthetase 0.65 AO356_18145 quinolinate synthase A — —
Pseudomonas fluorescens FW300-N2E2 0.71 Pf6N2E2_3609 Adenylosuccinate synthetase (EC 6.3.4.4) 0.66 Pf6N2E2_5553 Quinolinate synthetase (EC 2.5.1.72) — —
Pseudomonas syringae pv. syringae B728a 0.71 Psyr_0577 Adenylosuccinate synthetase 0.64 Psyr_1542 quinolinate synthetase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.71 Psyr_0577 Adenylosuccinate synthetase 0.64 Psyr_1542 quinolinate synthetase — —
Pseudomonas fluorescens GW456-L13 0.68 PfGW456L13_148 Adenylosuccinate synthetase (EC 6.3.4.4) 0.66 PfGW456L13_1863 Quinolinate synthetase (EC 2.5.1.72) — —
Pseudomonas simiae WCS417 0.68 PS417_02515 adenylosuccinate synthetase 0.65 PS417_22385 quinolinate synthase A — —
Pseudomonas stutzeri RCH2 0.68 Psest_0688 adenylosuccinate synthase 0.67 Psest_1509 quinolinate synthetase complex, A subunit — —
Pseudomonas fluorescens SBW25-INTG 0.68 PFLU_RS02595 adenylosuccinate synthase 0.65 PFLU_RS24025 quinolinate synthase NadA — —
Pseudomonas fluorescens SBW25 0.68 PFLU_RS02595 adenylosuccinate synthase 0.65 PFLU_RS24025 quinolinate synthase NadA — —
Kangiella aquimarina DSM 16071 0.67 B158DRAFT_1957 Adenylosuccinate synthetase (EC 6.3.4.4) 0.69 B158DRAFT_2453 quinolinate synthetase (EC 2.5.1.72) — —
Marinobacter adhaerens HP15 0.64 HP15_2494 adenlyosuccinate synthase 0.68 HP15_2032 quinolinate synthetase complex, A subunit — —
Acinetobacter radioresistens SK82 0.63 MPMX26_01090 Adenylosuccinate synthetase 0.68 MPMX26_02602 Quinolinate synthase A low > 36
Paraburkholderia sabiae LMG 24235 0.61 QEN71_RS06030 adenylosuccinate synthase 0.62 QEN71_RS03060 quinolinate synthase NadA — —
Rhodanobacter denitrificans MT42 0.60 LRK55_RS00375 adenylosuccinate synthase 0.23 LRK55_RS13615 quinolinate synthase NadA — —
Rhodanobacter denitrificans FW104-10B01 0.60 LRK54_RS00605 adenylosuccinate synthase 0.23 LRK54_RS13900 quinolinate synthase NadA — —
Cupriavidus basilensis FW507-4G11 0.59 RR42_RS13090 adenylosuccinate synthetase 0.64 RR42_RS17020 quinolinate synthetase — —
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_00527 Adenylosuccinate synthetase 0.61 H281DRAFT_04071 quinolinate synthetase — —
Rhodanobacter sp. FW510-T8 0.59 OKGIIK_06655 purA adenylosuccinate synthase 0.21 OKGIIK_00930 nadA quinolinate synthase NadA — —
Burkholderia phytofirmans PsJN 0.59 BPHYT_RS12525 adenylosuccinate synthetase 0.61 BPHYT_RS15650 quinolinate synthetase — —
Paraburkholderia graminis OAS925 0.59 ABIE53_002731 adenylosuccinate synthase 0.62 ABIE53_003294 quinolinate synthase — —
Ralstonia sp. UNC404CL21Col 0.59 ABZR87_RS10970 adenylosuccinate synthase 0.64 ABZR87_RS00355 quinolinate synthase NadA — —
Ralstonia solanacearum GMI1000 0.58 RS_RS06140 adenylosuccinate synthetase 0.63 RS_RS12295 quinolinate synthase — —
Ralstonia solanacearum PSI07 0.58 RPSI07_RS18045 adenylosuccinate synthase 0.63 RPSI07_RS12650 quinolinate synthase NadA — —
Ralstonia solanacearum IBSBF1503 0.58 RALBFv3_RS15330 adenylosuccinate synthase 0.63 RALBFv3_RS04735 quinolinate synthase NadA — —
Ralstonia solanacearum UW163 0.58 UW163_RS12795 adenylosuccinate synthase 0.63 UW163_RS08935 quinolinate synthase NadA — —
Herbaspirillum seropedicae SmR1 0.58 HSERO_RS14750 adenylosuccinate synthetase 0.62 HSERO_RS11065 quinolinate synthetase — —
Castellaniella sp019104865 MT123 0.57 ABCV34_RS02675 adenylosuccinate synthase 0.58 ABCV34_RS03700 quinolinate synthase NadA — —
Variovorax sp. SCN45 0.56 GFF1006 Adenylosuccinate synthetase (EC 6.3.4.4) 0.59 GFF2575 Quinolinate synthetase (EC 2.5.1.72) — —
Acidovorax sp. GW101-3H11 0.56 Ac3H11_1805 Adenylosuccinate synthetase (EC 6.3.4.4) 0.60 Ac3H11_3837 Quinolinate synthetase (EC 2.5.1.72) — —
Variovorax sp. OAS795 0.56 ABID97_RS14280 adenylosuccinate synthase 0.60 ABID97_RS07415 quinolinate synthase NadA — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.55 GFF4852 Adenylosuccinate synthetase (EC 6.3.4.4) 0.60 GFF1216 Quinolinate synthetase (EC 2.5.1.72) — —
Azospirillum sp. SherDot2 0.52 MPMX19_04815 Adenylosuccinate synthetase 0.23 MPMX19_05670 Quinolinate synthase A — —
Agrobacterium fabrum C58 0.51 Atu2447 adenylosuccinate synthetase 0.23 Atu4098 quinolinate synthetase — —
Azospirillum brasilense Sp245 0.50 AZOBR_RS10680 adenylosuccinate synthetase 0.22 AZOBR_RS18690 quinolinate synthetase — —
Rhodopseudomonas palustris CGA009 0.50 TX73_022255 adenylosuccinate synthase 0.23 TX73_005425 quinolinate synthase NadA — —
Mycobacterium tuberculosis H37Rv 0.50 Rv0357c Probable adenylosuccinate synthetase PurA (imp--aspartate ligase) (ADSS) (ampsase) 0.23 Rv1594 Probable quinolinate synthetase NadA — —
Magnetospirillum magneticum AMB-1 0.50 AMB_RS16115 adenylosuccinate synthetase 0.35 AMB_RS19660 quinolinate synthase NadA — —
Sinorhizobium meliloti 1021 0.50 SMc00643 adenylosuccinate synthetase 0.23 SMc02601 quinolinate synthetase — —
Rhodospirillum rubrum S1H 0.49 Rru_A1106 Adenylosuccinate synthase (NCBI) 0.23 Rru_A1434 Quinolinate synthetase A (NCBI) — —
Phaeobacter inhibens DSM 17395 0.48 PGA1_c23820 adenylosuccinate synthetase PurA 0.22 PGA1_c27790 quinolinate synthetase A — —
Caulobacter crescentus NA1000 0.48 CCNA_03201 adenylosuccinate synthetase 0.23 CCNA_03006 quinolinate synthetase A — —
Caulobacter crescentus NA1000 Δfur 0.48 CCNA_03201 adenylosuccinate synthetase 0.23 CCNA_03006 quinolinate synthetase A — —
Synechococcus elongatus PCC 7942 0.48 Synpcc7942_2409 purA adenylosuccinate synthetase 0.33 Synpcc7942_1448 nadA quinolinate synthetase — —
Desulfovibrio vulgaris Miyazaki F 0.48 DvMF_1939 adenylosuccinate synthetase (RefSeq) 0.13 DvMF_0525 quinolinate synthetase (RefSeq) — —
Rhizobium sp. OAE497 0.48 ABIE40_RS14805 adenylosuccinate synthase 0.24 ABIE40_RS23255 quinolinate synthase NadA — —
Brevundimonas sp. GW460-12-10-14-LB2 0.47 A4249_RS10075 adenylosuccinate synthase 0.24 A4249_RS00620 quinolinate synthase NadA — —
Desulfovibrio vulgaris Hildenborough JW710 0.47 DVU3204 purA adenylosuccinate synthetase (TIGR) 0.13 DVU1808 nadA quinolinate synthetase complex, subunit A (TIGR) — —
Sphingomonas koreensis DSMZ 15582 0.46 Ga0059261_2472 Adenylosuccinate synthetase (EC 6.3.4.4) 0.36 Ga0059261_0051 quinolinate synthetase (EC 2.5.1.72) — —
Fusobacterium nucleatum SB010 0.43 HUW76_01605 adenylosuccinate synthase 0.27 HUW76_10740 quinolinate synthase NadA low > 35
Bacteroides ovatus ATCC 8483 0.42 BACOVA_04589 adenylosuccinate synthase 0.34 BACOVA_02839 quinolinate synthetase complex, A subunit 0.80 61
Bacteroides thetaiotaomicron VPI-5482 0.41 BT1843 adenylosuccinate synthetase (NCBI ptt file) 0.35 BT3164 quinolinate synthetase A (NCBI ptt file) low > 81
Parabacteroides merdae CL09T00C40 0.41 HMPREF1078_RS13135 adenylosuccinate synthase 0.34 HMPREF1078_RS06555 quinolinate synthase NadA — —
Bacteroides stercoris CC31F 0.41 HMPREF1181_RS14085 adenylosuccinate synthase 0.35 HMPREF1181_RS01920 quinolinate synthase NadA — —
Phocaeicola vulgatus CL09T03C04 0.41 HMPREF1058_RS14610 adenylosuccinate synthase 0.36 HMPREF1058_RS11230 quinolinate synthase NadA — —
Phocaeicola dorei CL03T12C01 0.41 ABI39_RS10260 adenylosuccinate synthase 0.36 ABI39_RS05755 quinolinate synthase NadA — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.39 ABZR88_RS15620 adenylosuccinate synthase 0.36 ABZR88_RS20650 quinolinate synthase NadA — —
Pedobacter sp. GW460-11-11-14-LB5 0.36 CA265_RS14495 adenylosuccinate synthase 0.34 CA265_RS21180 quinolinate synthase — —
Methanococcus maripaludis JJ 0.23 MMJJ_RS06990 adenylosuccinate synthetase 0.20 MMJJ_RS07960 quinolinate synthase NadA — —
Methanococcus maripaludis S2 0.23 MMP_RS07370 adenylosuccinate synthetase 0.20 MMP_RS06390 quinolinate synthase NadA — —

Not shown: 10 genomes with orthologs for b4177 only; 0 genomes with orthologs for b0750 only