Conservation of cofitness between Xcc-8004.1710.1 and Xcc-8004.1053.1 in Xanthomonas campestris pv. campestris strain 8004

95 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Xanthomonas campestris pv. campestris strain 8004 1.0 Xcc-8004.1710.1 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 1.0 Xcc-8004.1053.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.62 17
Lysobacter sp. OAE881 0.59 ABIE51_RS16065 pyrroline-5-carboxylate reductase 0.44 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.87 16
Dyella japonica UNC79MFTsu3.2 0.49 ABZR86_RS10425 pyrroline-5-carboxylate reductase 0.39 ABZR86_RS15950 3-isopropylmalate dehydrogenase 0.86 58
Rhodanobacter sp. FW510-T8 0.47 OKGIIK_11135 proC pyrroline-5-carboxylate reductase 0.41 OKGIIK_13595 leuB 3-isopropylmalate dehydrogenase low > 52
Pseudomonas sp. S08-1 0.46 OH686_10980 pyrroline-5-carboxylate reductase 0.81 OH686_04470 3-isopropylmalate dehydrogenase 0.66 28
Rhodanobacter denitrificans MT42 0.45 LRK55_RS04030 pyrroline-5-carboxylate reductase 0.42 LRK55_RS09965 3-isopropylmalate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS04260 pyrroline-5-carboxylate reductase 0.41 LRK54_RS10325 3-isopropylmalate dehydrogenase 0.82 9
Pseudomonas stutzeri RCH2 0.44 Psest_0283 pyrroline-5-carboxylate reductase 0.80 Psest_2589 3-isopropylmalate dehydrogenase — —
Pseudomonas putida KT2440 0.43 PP_5095 pyrroline-5-carboxylate reductase 0.78 PP_1988 3-isopropylmalate dehydrogenase 0.44 18
Pseudomonas fluorescens FW300-N2E2 0.43 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.79 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) — —
Pseudomonas fluorescens FW300-N2C3 0.42 AO356_13420 pyrroline-5-carboxylate reductase 0.79 AO356_21415 3-isopropylmalate dehydrogenase — —
Pseudomonas sp. RS175 0.41 PFR28_04243 Pyrroline-5-carboxylate reductase 0.78 PFR28_02821 3-isopropylmalate dehydrogenase — —
Pseudomonas syringae pv. syringae B728a 0.41 Psyr_0476 pyrroline-5-carboxylate reductase 0.78 Psyr_1985 3-isopropylmalate dehydrogenase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.41 Psyr_0476 pyrroline-5-carboxylate reductase 0.78 Psyr_1985 3-isopropylmalate dehydrogenase 0.82 15
Pseudomonas fluorescens FW300-N1B4 0.41 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.78 Pf1N1B4_12 3-isopropylmalate dehydrogenase (EC 1.1.1.85) — —
Pseudomonas fluorescens FW300-N2E3 0.41 AO353_08165 pyrroline-5-carboxylate reductase 0.77 AO353_20635 3-isopropylmalate dehydrogenase 0.65 27
Pseudomonas fluorescens SBW25-INTG 0.41 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.79 PFLU_RS20565 3-isopropylmalate dehydrogenase — —
Pseudomonas fluorescens SBW25 0.41 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.79 PFLU_RS20565 3-isopropylmalate dehydrogenase — —
Pseudomonas simiae WCS417 0.41 PS417_26730 pyrroline-5-carboxylate reductase 0.79 PS417_18585 3-isopropylmalate dehydrogenase 0.57 13
Pseudomonas fluorescens GW456-L13 0.40 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.79 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.94 3
Marinobacter adhaerens HP15 0.37 HP15_287 pyrroline-5-carboxylate reductase 0.66 HP15_1832 3-isopropylmalate dehydrogenase 0.76 1
Dechlorosoma suillum PS 0.36 Dsui_0602 pyrroline-5-carboxylate reductase 0.62 Dsui_3198 3-isopropylmalate dehydrogenase — —
Variovorax sp. OAS795 0.35 ABID97_RS01555 pyrroline-5-carboxylate reductase 0.59 ABID97_RS08455 3-isopropylmalate dehydrogenase — —
Paraburkholderia sabiae LMG 24235 0.35 QEN71_RS26600 pyrroline-5-carboxylate reductase 0.57 QEN71_RS17620 3-isopropylmalate dehydrogenase 0.81 57
Kangiella aquimarina DSM 16071 0.35 B158DRAFT_0197 pyrroline-5-carboxylate reductase 0.65 B158DRAFT_1322 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 40
Ralstonia sp. UNC404CL21Col 0.34 ABZR87_RS01230 pyrroline-5-carboxylate reductase 0.58 ABZR87_RS14530 3-isopropylmalate dehydrogenase — —
Acidovorax sp. GW101-3H11 0.34 Ac3H11_788 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.59 Ac3H11_1528 3-isopropylmalate dehydrogenase (EC 1.1.1.85) — —
Acinetobacter radioresistens SK82 0.34 MPMX26_00572 Pyrroline-5-carboxylate reductase 0.67 MPMX26_00348 3-isopropylmalate dehydrogenase low > 36
Ralstonia solanacearum GMI1000 0.34 RS_RS13440 pyrroline-5-carboxylate reductase 0.59 RS_RS09990 3-isopropylmalate dehydrogenase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.33 GFF2806 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.59 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 90
Paraburkholderia graminis OAS925 0.33 ABIE53_000840 pyrroline-5-carboxylate reductase 0.58 ABIE53_004804 3-isopropylmalate dehydrogenase 0.62 11
Variovorax sp. SCN45 0.33 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.59 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) — —
Ralstonia solanacearum IBSBF1503 0.33 RALBFv3_RS05580 pyrroline-5-carboxylate reductase 0.58 RALBFv3_RS02610 3-isopropylmalate dehydrogenase 0.52 36
Ralstonia solanacearum UW163 0.33 UW163_RS08045 pyrroline-5-carboxylate reductase 0.58 UW163_RS11115 3-isopropylmalate dehydrogenase — —
Paraburkholderia bryophila 376MFSha3.1 0.33 H281DRAFT_04679 pyrroline-5-carboxylate reductase 0.58 H281DRAFT_06072 3-isopropylmalate dehydrogenase 0.61 17
Ralstonia solanacearum PSI07 0.33 RPSI07_RS11720 pyrroline-5-carboxylate reductase 0.58 RPSI07_RS14705 3-isopropylmalate dehydrogenase 0.78 4
Dickeya dadantii 3937 0.32 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.47 DDA3937_RS18120 3-isopropylmalate dehydrogenase low > 74
Burkholderia phytofirmans PsJN 0.32 BPHYT_RS03490 pyrroline-5-carboxylate reductase 0.58 BPHYT_RS33900 3-isopropylmalate dehydrogenase — —
Shewanella oneidensis MR-1 0.32 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) 0.47 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.97 11
Shewanella sp. ANA-3 0.32 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) 0.47 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.93 22
Serratia liquefaciens MT49 0.32 IAI46_21415 pyrroline-5-carboxylate reductase 0.48 IAI46_03350 3-isopropylmalate dehydrogenase 0.61 37
Cupriavidus basilensis FW507-4G11 0.32 RR42_RS17360 pyrroline-5-carboxylate reductase 0.58 RR42_RS14385 3-isopropylmalate dehydrogenase — —
Dickeya dianthicola ME23 0.32 DZA65_RS18440 pyrroline-5-carboxylate reductase 0.47 DZA65_RS19205 3-isopropylmalate dehydrogenase — —
Dickeya dianthicola 67-19 0.32 HGI48_RS17350 pyrroline-5-carboxylate reductase 0.47 HGI48_RS18060 3-isopropylmalate dehydrogenase — —
Shewanella loihica PV-4 0.30 Shew_3016 pyrroline-5-carboxylate reductase (RefSeq) 0.47 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) low > 60
Herbaspirillum seropedicae SmR1 0.30 HSERO_RS18990 pyrroline-5-carboxylate reductase 0.59 HSERO_RS16500 3-isopropylmalate dehydrogenase 0.80 12
Rahnella sp. WP5 0.30 EX31_RS02690 pyrroline-5-carboxylate reductase 0.48 EX31_RS03685 3-isopropylmalate dehydrogenase 0.98 3
Shewanella amazonensis SB2B 0.30 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) 0.47 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) 0.93 35
Vibrio cholerae E7946 ATCC 55056 0.30 CSW01_02450 pyrroline-5-carboxylate reductase 0.48 CSW01_12600 3-isopropylmalate dehydrogenase low > 62
Alteromonas macleodii MIT1002 0.30 MIT1002_03062 Pyrroline-5-carboxylate reductase 0.46 MIT1002_00948 3-isopropylmalate dehydrogenase 0.94 36
Pectobacterium carotovorum WPP14 0.30 HER17_RS03805 pyrroline-5-carboxylate reductase 0.47 HER17_RS03080 3-isopropylmalate dehydrogenase — —
Castellaniella sp019104865 MT123 0.29 ABCV34_RS03610 pyrroline-5-carboxylate reductase 0.60 ABCV34_RS04280 3-isopropylmalate dehydrogenase low > 48
Magnetospirillum magneticum AMB-1 0.28 AMB_RS02820 pyrroline-5-carboxylate reductase 0.52 AMB_RS20570 3-isopropylmalate dehydrogenase — —
Azospirillum sp. SherDot2 0.28 MPMX19_01399 Pyrroline-5-carboxylate reductase 0.52 MPMX19_00607 3-isopropylmalate dehydrogenase — —
Rhodospirillum rubrum S1H 0.27 Rru_A3281 Delta 1-pyrroline-5-carboxylate reductase (NCBI) 0.53 Rru_A1191 3-isopropylmalate dehydrogenase (NCBI) — —
Agrobacterium fabrum C58 0.27 Atu2209 pyrroline-5-carboxylate reductase 0.52 Atu2791 3-isopropylmalate dehydrogenase 0.65 16
Azospirillum brasilense Sp245 0.27 AZOBR_RS06245 pyrroline-5-carboxylate reductase 0.51 AZOBR_RS14130 3-isopropylmalate dehydrogenase — —
Phaeobacter inhibens DSM 17395 0.26 PGA1_c24700 pyrroline-5-carboxylate reductase ProC 0.55 PGA1_c29830 3-isopropylmalate dehydrogenase LeuB 0.85 8
Synechococcus elongatus PCC 7942 0.26 Synpcc7942_2058 proC pyrroline-5-carboxylate reductase 0.52 Synpcc7942_1505 leuB 3-isopropylmalate dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.25 TX73_022630 pyrroline-5-carboxylate reductase 0.48 TX73_001175 3-isopropylmalate dehydrogenase — —
Rhizobium sp. OAE497 0.25 ABIE40_RS13005 pyrroline-5-carboxylate reductase 0.52 ABIE40_RS19050 3-isopropylmalate dehydrogenase 0.71 20
Escherichia fergusonii Becca 0.24 EFB2_03670 Pyrroline-5-carboxylate reductase 0.47 EFB2_03972 3-isopropylmalate dehydrogenase low > 86
Klebsiella michiganensis M5al 0.24 BWI76_RS06170 pyrroline-5-carboxylate reductase 0.48 BWI76_RS04675 3-isopropylmalate dehydrogenase — —
Escherichia coli Nissle 1917 0.24 ECOLIN_RS02345 pyrroline-5-carboxylate reductase 0.47 ECOLIN_RS00395 3-isopropylmalate dehydrogenase 0.91 4
Escherichia coli ECRC102 0.24 NIAGMN_06665 proC pyrroline-5-carboxylate reductase 0.47 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECOR38 0.24 HEPCGN_07250 proC pyrroline-5-carboxylate reductase 0.47 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase 0.85 26
Escherichia coli ECRC101 0.24 MCAODC_27835 proC pyrroline-5-carboxylate reductase 0.47 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase 0.87 9
Escherichia coli ECRC99 0.24 KEDOAH_19355 proC pyrroline-5-carboxylate reductase 0.47 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC98 0.24 JDDGAC_12265 proC pyrroline-5-carboxylate reductase 0.47 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase low > 86
Escherichia coli ECRC100 0.24 OKFHMN_08610 proC pyrroline-5-carboxylate reductase 0.47 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase 0.86 38
Escherichia coli ECOR27 0.24 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 0.47 NOLOHH_03065 leuA 2-isopropylmalate synthase 0.91 10
Escherichia coli HS(pFamp)R (ATCC 700891) 0.24 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase 0.47 OHPLBJKB_03584 3-isopropylmalate dehydrogenase low > 73
Escherichia coli BL21 0.24 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding 0.47 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent 0.84 5
Escherichia coli BW25113 0.24 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.47 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.87 12
Escherichia coli ECRC62 0.24 BNILDI_22950 proC pyrroline-5-carboxylate reductase 0.47 BNILDI_08545 leuA 2-isopropylmalate synthase 0.84 4
Pantoea sp. MT58 0.24 IAI47_14945 pyrroline-5-carboxylate reductase 0.45 IAI47_16005 3-isopropylmalate dehydrogenase 0.83 25
Enterobacter asburiae PDN3 0.23 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.49 EX28DRAFT_3669 3-isopropylmalate dehydrogenase 0.56 51
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.23 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.47 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 78
Enterobacter sp. TBS_079 0.23 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.48 MPMX20_00768 3-isopropylmalate dehydrogenase 0.85 42
Bosea sp. OAE506 0.21 ABIE41_RS11365 pyrroline-5-carboxylate reductase 0.49 ABIE41_RS11860 3-isopropylmalate dehydrogenase — —
Erwinia tracheiphila SCR3 0.21 LU632_RS18995 proC pyrroline-5-carboxylate reductase 0.44 LU632_RS02875 leuB 3-isopropylmalate dehydrogenase 0.62 23
Dinoroseobacter shibae DFL-12 0.21 Dshi_2645 pyrroline-5-carboxylate reductase (RefSeq) 0.55 Dshi_0081 3-isopropylmalate dehydrogenase (RefSeq) — —
Mycobacterium tuberculosis H37Rv 0.20 Rv0500 Probable pyrroline-5-carboxylate reductase ProC (P5CR) (P5C reductase) 0.26 Rv2995c Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.20 Echvi_2635 pyrroline-5-carboxylate reductase 0.41 Echvi_2062 3-isopropylmalate dehydrogenase — —
Desulfovibrio vulgaris Hildenborough JW710 0.20 DVU2332 proC pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.53 DVU2985 leuB 3-isopropylmalate dehydrogenase (TIGR) 0.85 13
Caulobacter crescentus NA1000 0.18 CCNA_00528 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.48 CCNA_00193 3-isopropylmalate dehydrogenase 0.92 18
Caulobacter crescentus NA1000 Δfur 0.18 CCNA_00528 pyrroline-5-carboxylate reductase 0.48 CCNA_00193 3-isopropylmalate dehydrogenase low > 67
Desulfovibrio vulgaris Miyazaki F 0.16 DvMF_3161 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.57 DvMF_1794 3-isopropylmalate dehydrogenase (RefSeq) 0.92 12
Phocaeicola dorei CL03T12C01 0.16 ABI39_RS02960 pyrroline-5-carboxylate reductase 0.39 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.83 11
Pontibacter actiniarum KMM 6156, DSM 19842 0.15 CA264_07730 pyrroline-5-carboxylate reductase 0.40 CA264_09445 3-isopropylmalate dehydrogenase low > 74
Phocaeicola vulgatus CL09T03C04 0.15 HMPREF1058_RS08830 pyrroline-5-carboxylate reductase 0.39 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase 0.79 46
Brevundimonas sp. GW460-12-10-14-LB2 0.15 A4249_RS09840 pyrroline-5-carboxylate reductase dimerization domain-containing protein 0.41 A4249_RS09995 3-isopropylmalate dehydrogenase 0.97 19
Bacteroides ovatus ATCC 8483 0.15 BACOVA_03587 pyrroline-5-carboxylate reductase 0.38 BACOVA_04600 3-isopropylmalate dehydrogenase 0.90 11
Bacteroides stercoris CC31F 0.15 HMPREF1181_RS03440 pyrroline-5-carboxylate reductase 0.40 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase 0.89 34
Mucilaginibacter yixingensis YX-36 DSM 26809 0.14 ABZR88_RS09865 pyrroline-5-carboxylate reductase 0.47 ABZR88_RS11605 3-isopropylmalate dehydrogenase — —
Bacteroides thetaiotaomicron VPI-5482 0.13 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.39 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.84 34

Not shown: 1 genomes with orthologs for Xcc-8004.1710.1 only; 4 genomes with orthologs for Xcc-8004.1053.1 only