| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Azospirillum sp. SherDot2 | 1.0 | MPMX19_00882 | | Metalloprotease TldD | 1.0 | MPMX19_02313 | | Oxygen-independent coproporphyrinogen III oxidase | 0.58 | 7 |
| Azospirillum brasilense Sp245 | 0.90 | AZOBR_RS10600 | | peptidase C69 | 0.76 | AZOBR_RS03710 | | coproporphyrinogen III oxidase | low | > 97 |
| Magnetospirillum magneticum AMB-1 | 0.69 | AMB_RS21030 | | metalloprotease TldD | 0.50 | AMB_RS13570 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Rhodospirillum rubrum S1H | 0.66 | Rru_A0567 | | Peptidase U62, modulator of DNA gyrase (NCBI) | 0.52 | Rru_A2504 | | Oxygen-independent coproporphyrinogen III oxidase HemN (NCBI) | — | — |
| Rhizobium sp. OAE497 | 0.64 | ABIE40_RS04050 | | metalloprotease TldD | 0.46 | ABIE40_RS26250 | | oxygen-independent coproporphyrinogen III oxidase | low | > 107 |
| Agrobacterium fabrum C58 | 0.64 | Atu0765 | | TldD | 0.42 | Atu1601 | | oxygen-independent coproporphyrinogen III oxidase | low | > 89 |
| Sinorhizobium meliloti 1021 | 0.61 | SMc00960 | | hypothetical protein | 0.48 | SMa1266 | | coproporphyrinogen III oxidase | low | > 103 |
| Rhodopseudomonas palustris CGA009 | 0.61 | TX73_004255 | | metalloprotease TldD | 0.46 | TX73_008565 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.59 | CCNA_03522 | | Zn-dependent protease TldD | 0.41 | CCNA_01477 | | oxygen-independent coproporphyrinogen-III oxidase hemN | low | > 67 |
| Caulobacter crescentus NA1000 | 0.59 | CCNA_03522 | | Zn-dependent protease TldD | 0.41 | CCNA_01477 | | oxygen-independent coproporphyrinogen-III oxidase hemN | low | > 66 |
| Sphingobium sp. HT1-2 | 0.58 | GFF782 | | TldD protein, part of TldE/TldD proteolytic complex | 0.31 | GFF4340 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | low | > 95 |
| Phaeobacter inhibens DSM 17395 | 0.57 | PGA1_c06240 | | protein TldD | 0.35 | PGA1_c00360 | | oxygen-independent coproporphyrinogen III oxidase HemN | low | > 62 |
| Methylophilus sp. DMC18 | 0.55 | GFF380 | | Metalloprotease TldD | 0.32 | GFF1090 | | Oxygen-independent coproporphyrinogen III oxidase | low | > 43 |
| Dinoroseobacter shibae DFL-12 | 0.55 | Dshi_1139 | | peptidase U62 modulator of DNA gyrase (RefSeq) | 0.44 | Dshi_0541 | | oxygen-independent coproporphyrinogen III oxidase (RefSeq) | low | > 64 |
| Cupriavidus basilensis FW507-4G11 | 0.54 | RR42_RS05875 | | protease TldD | 0.34 | RR42_RS20025 | | coproporphyrinogen III oxidase | low | > 128 |
| Pseudomonas sp. BP01 | 0.53 | JOY50_RS11070 | tldD | metalloprotease TldD | 0.32 | JOY50_RS00120 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 84 |
| Ralstonia solanacearum GMI1000 | 0.53 | RS_RS13315 | | metalloprotease TldD | 0.33 | RS_RS16455 | | oxygen-independent coproporphyrinogen III oxidase | low | > 80 |
| Pseudomonas putida KT2440 | 0.53 | PP_0940 | | putative protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD | 0.32 | PP_4264 | | oxygen-independent coproporphyrinogen III dehydrogenase | low | > 96 |
| Rhodanobacter sp. FW510-T8 | 0.53 | OKGIIK_10280 | tldD | metalloprotease TldD | 0.32 | OKGIIK_00800 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 53 |
| Ralstonia solanacearum UW163 | 0.53 | UW163_RS08170 | | metalloprotease TldD | 0.34 | UW163_RS05010 | | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.53 | ABZR86_RS21715 | | metalloprotease TldD | 0.33 | ABZR86_RS04455 | | oxygen-independent coproporphyrinogen III oxidase | low | > 74 |
| Ralstonia solanacearum IBSBF1503 | 0.53 | RALBFv3_RS05455 | | metalloprotease TldD | 0.34 | RALBFv3_RS08600 | | oxygen-independent coproporphyrinogen III oxidase | low | > 76 |
| Variovorax sp. SCN45 | 0.53 | GFF4449 | | TldD protein, part of TldE/TldD proteolytic complex | 0.30 | GFF6957 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | low | > 127 |
| Ralstonia sp. UNC404CL21Col | 0.53 | ABZR87_RS01105 | | metalloprotease TldD | 0.33 | ABZR87_RS03910 | | oxygen-independent coproporphyrinogen III oxidase | low | > 80 |
| Rhodanobacter sp000427505 FW510-R12 | 0.53 | LRK53_RS06565 | | metalloprotease TldD | 0.34 | LRK53_RS17200 | | oxygen-independent coproporphyrinogen III oxidase | low | > 59 |
| Pseudomonas syringae pv. syringae B728a | 0.53 | Psyr_4156 | | microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 | 0.28 | Psyr_3423 | | coproporphyrinogen III oxidase, anaerobic | low | > 86 |
| Herbaspirillum seropedicae SmR1 | 0.53 | HSERO_RS07155 | | peptidase C69 | 0.33 | HSERO_RS16075 | | coproporphyrinogen III oxidase | low | > 78 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.53 | Psyr_4156 | | microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 | 0.28 | Psyr_3423 | | coproporphyrinogen III oxidase, anaerobic | low | > 86 |
| Pseudomonas sp. SVBP6 | 0.53 | COO64_RS04225 | tldD | metalloprotease TldD | 0.31 | COO64_RS18645 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 93 |
| Variovorax sp. OAS795 | 0.52 | ABID97_RS06335 | | metalloprotease TldD | 0.31 | ABID97_RS16190 | | oxygen-independent coproporphyrinogen III oxidase | low | > 91 |
| Lysobacter sp. OAE881 | 0.52 | ABIE51_RS06795 | | metalloprotease TldD | 0.31 | ABIE51_RS03875 | | oxygen-independent coproporphyrinogen III oxidase | low | > 62 |
| Acidovorax sp. GW101-3H11 | 0.52 | Ac3H11_4036 | | TldD protein, part of TldE/TldD proteolytic complex | 0.30 | Ac3H11_976 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | low | > 79 |
| Pseudomonas segetis P6 | 0.52 | ACVTMO_RS19155 | tldD | metalloprotease TldD | 0.30 | ACVTMO_RS11465 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 75 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.52 | Xcc-8004.1883.1 | | TldD protein, part of TldE/TldD proteolytic complex | 0.30 | Xcc-8004.2605.1 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | low | > 74 |
| Burkholderia phytofirmans PsJN | 0.52 | BPHYT_RS03540 | | peptidase C69 | 0.34 | BPHYT_RS15490 | | coproporphyrinogen III oxidase | low | > 109 |
| Paraburkholderia sabiae LMG 24235 | 0.52 | QEN71_RS26555 | | metalloprotease TldD | 0.34 | QEN71_RS03200 | | oxygen-independent coproporphyrinogen III oxidase | low | > 153 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.52 | GFF580 | | TldD protein, part of TldE/TldD proteolytic complex | 0.33 | GFF4143 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | low | > 90 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.52 | H281DRAFT_04688 | | microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 | 0.34 | H281DRAFT_04040 | | oxygen-independent coproporphyrinogen-3 oxidase | low | > 103 |
| Alteromonas macleodii MIT1002 | 0.52 | MIT1002_00227 | | protease TldD | 0.32 | MIT1002_02323 | | Oxygen-independent coproporphyrinogen-III oxidase | low | > 70 |
| Rhodanobacter denitrificans MT42 | 0.52 | LRK55_RS03145 | | metalloprotease TldD | 0.34 | LRK55_RS05590 | | oxygen-independent coproporphyrinogen III oxidase | low | > 63 |
| Paraburkholderia graminis OAS925 | 0.52 | ABIE53_000851 | | TldD protein | 0.34 | ABIE53_003264 | | oxygen-independent coproporphyrinogen-3 oxidase | low | > 113 |
| Pseudomonas aeruginosa PA14 | 0.52 | IKLFDK_01710 | | metalloprotease TldD | 0.31 | IKLFDK_07385 | | oxygen-independent coproporphyrinogen III oxidase | low | > 98 |
| Ralstonia solanacearum PSI07 | 0.52 | RPSI07_RS11850 | | metalloprotease TldD | 0.33 | RPSI07_RS08635 | | oxygen-independent coproporphyrinogen III oxidase | low | > 81 |
| Pseudomonas aeruginosa PUPa3 | 0.52 | DQ20_RS56565 | tldD;go_function=metallopeptidase | metalloprotease TldD | 0.31 | DQ20_RS53485 | hemN;go_function=coproporphyrinogen | oxygen-independent coproporphyrinogen III oxidase | low | > 101 |
| Rhodanobacter denitrificans FW104-10B01 | 0.52 | LRK54_RS03395 | | metalloprotease TldD | 0.34 | LRK54_RS05835 | | oxygen-independent coproporphyrinogen III oxidase | low | > 59 |
| Pseudomonas aeruginosa MRSN321 | 0.52 | DY961_RS24105 | tldD;go_function=metallopeptidase | metalloprotease TldD | 0.31 | DY961_RS19355 | hemN;go_function=coproporphyrinogen | oxygen-independent coproporphyrinogen III oxidase | low | > 100 |
| Pseudomonas sp. DMC3 | 0.51 | GFF1816 | | Metalloprotease TldD | 0.31 | GFF713 | | Oxygen-independent coproporphyrinogen III oxidase | 0.59 | 22 |
| Pseudomonas fluorescens SBW25 | 0.51 | PFLU_RS04340 | | metalloprotease TldD | 0.31 | PFLU_RS22385 | | oxygen-independent coproporphyrinogen III oxidase | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.51 | PFLU_RS04340 | | metalloprotease TldD | 0.31 | PFLU_RS22385 | | oxygen-independent coproporphyrinogen III oxidase | low | > 109 |
| Pseudomonas fluorescens FW300-N2E2 | 0.51 | Pf6N2E2_3280 | | TldD protein, part of TldE/TldD proteolytic complex | 0.30 | Pf6N2E2_1410 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | low | > 103 |
| Pseudomonas orientalis W4I3 | 0.51 | QF045_RS07275 | | metalloprotease TldD | 0.32 | QF045_RS22580 | | oxygen-independent coproporphyrinogen III oxidase | low | > 93 |
| Pseudomonas lactucae CFBP13502 | 0.51 | GEMAOFIL_01062 | | Metalloprotease TldD | 0.31 | GEMAOFIL_04300 | | Oxygen-independent coproporphyrinogen III oxidase | low | > 96 |
| Pseudomonas simiae WCS417 | 0.51 | PS417_04285 | | protease TldD | 0.31 | PS417_20775 | | coproporphyrinogen III oxidase | low | > 88 |
| Pseudomonas fluorescens FW300-N2C3 | 0.51 | AO356_07095 | | protease TldD | 0.30 | AO356_02480 | | coproporphyrinogen III oxidase | low | > 104 |
| Dechlorosoma suillum PS | 0.51 | Dsui_3401 | | putative Zn-dependent protease-like protein | 0.34 | Dsui_1647 | | oxygen-independent coproporphyrinogen III oxidase | low | > 51 |
| Pseudomonas fluorescens FW300-N2E3 | 0.51 | AO353_05215 | | protease TldD | 0.32 | AO353_00655 | | coproporphyrinogen III oxidase | low | > 101 |
| Pseudomonas fluorescens FW300-N1B4 | 0.51 | Pf1N1B4_1092 | | TldD protein, part of TldE/TldD proteolytic complex | 0.32 | Pf1N1B4_3868 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | low | > 87 |
| Pseudomonas fluorescens GW456-L13 | 0.51 | PfGW456L13_5026 | | TldD protein, part of TldE/TldD proteolytic complex | 0.32 | PfGW456L13_4070 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | low | > 87 |
| Pseudomonas sp. RS175 | 0.50 | PFR28_00161 | | Metalloprotease TldD | 0.32 | PFR28_01080 | | Oxygen-independent coproporphyrinogen III oxidase | low | > 88 |
| Shewanella loihica PV-4 | 0.50 | Shew_0410 | | peptidase U62, modulator of DNA gyrase (RefSeq) | 0.34 | Shew_3720 | | coproporphyrinogen III oxidase (RefSeq) | low | > 60 |
| Pseudomonas sp. S08-1 | 0.50 | OH686_08580 | | TldD protein, part of TldE/TldD proteolytic complex | 0.30 | OH686_02235 | | oxygen-independent coproporphyrinogen III oxidase | low | > 80 |
| Pseudomonas stutzeri RCH2 | 0.49 | Psest_3320 | | Predicted Zn-dependent proteases and their inactivated homologs | 0.32 | Psest_2234 | | oxygen-independent coproporphyrinogen III oxidase | low | > 67 |
| Kangiella aquimarina DSM 16071 | 0.49 | B158DRAFT_2072 | | microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 | 0.33 | B158DRAFT_1981 | | coproporphyrinogen III oxidase, anaerobic (EC 1.3.99.22) | low | > 40 |
| Klebsiella pneumoniae MKP103 | 0.49 | KDGMDA_06245 | | metalloprotease TldD | 0.33 | KDGMDA_08995 | | oxygen-independent coproporphyrinogen III oxidase | low | > 95 |
| Shewanella sp. ANA-3 | 0.49 | Shewana3_3641 | | microcin-processing peptidase 2 (RefSeq) | 0.32 | Shewana3_4116 | | coproporphyrinogen III oxidase (RefSeq) | low | > 73 |
| Pantoea sp. MT58 | 0.49 | IAI47_02465 | | metalloprotease TldD | 0.33 | IAI47_00445 | | oxygen-independent coproporphyrinogen III oxidase | low | > 76 |
| Serratia liquefaciens MT49 | 0.49 | IAI46_22685 | | metalloprotease TldD | 0.33 | IAI46_24970 | | oxygen-independent coproporphyrinogen III oxidase | low | > 87 |
| Vibrio cholerae E7946 ATCC 55056 | 0.49 | CSW01_02220 | | metalloprotease TldD | 0.33 | CSW01_00590 | | oxygen-independent coproporphyrinogen III oxidase | low | > 62 |
| Erwinia amylovora T8 | 0.49 | OLJFJH_06940 | | metalloprotease TldD | 0.31 | OLJFJH_05490 | | oxygen-independent coproporphyrinogen III oxidase | low | > 58 |
| Pantoea agglomerans CFBP13505 P0401 | 0.49 | PagCFBP13505_RS11060 | | metalloprotease TldD | 0.32 | PagCFBP13505_RS18900 | | oxygen-independent coproporphyrinogen III oxidase | low | > 74 |
| Enterobacter sp. TBS_079 | 0.49 | MPMX20_04151 | | Metalloprotease TldD | 0.32 | MPMX20_04598 | | Oxygen-independent coproporphyrinogen III oxidase | low | > 85 |
| Klebsiella michiganensis M5al | 0.49 | BWI76_RS25470 | | metalloprotease TldD | 0.34 | BWI76_RS00380 | | oxygen-independent coproporphyrinogen III oxidase | low | > 92 |
| Pectobacterium carotovorum WPP14 | 0.48 | HER17_RS20140 | | metalloprotease TldD | 0.31 | HER17_RS21450 | | oxygen-independent coproporphyrinogen III oxidase | low | > 75 |
| Shewanella oneidensis MR-1 | 0.48 | SO4091 | tldD | tldD protein (NCBI ptt file) | 0.33 | SO4730 | hemN | oxygen-independent coproporphyrinogen III oxidase (NCBI ptt file) | low | > 76 |
| Castellaniella sp019104865 MT123 | 0.48 | ABCV34_RS02590 | | metalloprotease TldD | 0.33 | ABCV34_RS06465 | | oxygen-independent coproporphyrinogen III oxidase | low | > 48 |
| Dickeya dadantii 3937 | 0.48 | DDA3937_RS01460 | | metalloprotease TldD | 0.33 | DDA3937_RS00120 | | oxygen-independent coproporphyrinogen III oxidase | low | > 74 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.48 | GFF2140 | | TldD protein, part of TldE/TldD proteolytic complex | 0.33 | GFF2219 | | Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) | low | > 78 |
| Escherichia coli ECOR27 | 0.48 | NOLOHH_09555 | tldD | metalloprotease TldD | 0.33 | NOLOHH_06250 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 76 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.48 | OHPLBJKB_00460 | | Metalloprotease TldD | 0.33 | OHPLBJKB_04186 | | Oxygen-independent coproporphyrinogen III oxidase | low | > 74 |
| Escherichia coli BL21 | 0.48 | ECD_03104 | | putative peptidase | 0.33 | ECD_03752 | | coproporphyrinogen III oxidase, SAM and NAD(P)H dependent, oxygen-independent | low | > 61 |
| Escherichia coli BW25113 | 0.48 | b3244 | tldD | predicted peptidase (NCBI) | 0.33 | b3867 | hemN | O2-independent coproporphyrinogen III oxidase (VIMSS) | low | > 76 |
| Escherichia coli ECRC62 | 0.48 | BNILDI_01980 | tldD | metalloprotease TldD | 0.33 | BNILDI_05280 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 75 |
| Escherichia coli Nissle 1917 | 0.48 | ECOLIN_RS18595 | | metalloprotease TldD | 0.33 | ECOLIN_RS22285 | | oxygen-independent coproporphyrinogen III oxidase | low | > 55 |
| Escherichia fergusonii Becca | 0.48 | EFB2_00586 | | Metalloprotease TldD | 0.33 | EFB2_04750 | | Oxygen-independent coproporphyrinogen III oxidase | low | > 86 |
| Escherichia coli ECOR38 | 0.48 | HEPCGN_16620 | tldD | metalloprotease TldD | 0.33 | HEPCGN_12755 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 88 |
| Escherichia coli ECRC98 | 0.48 | JDDGAC_21380 | tldD | metalloprotease TldD | 0.33 | JDDGAC_17745 | hemN | oxygen-independent coproporphyrinogen III oxidase | 0.43 | 84 |
| Dickeya dianthicola 67-19 | 0.48 | HGI48_RS01380 | | metalloprotease TldD | 0.32 | HGI48_RS21245 | | oxygen-independent coproporphyrinogen III oxidase | low | > 71 |
| Escherichia coli ECRC101 | 0.48 | MCAODC_08275 | tldD | metalloprotease TldD | 0.33 | MCAODC_04620 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 87 |
| Escherichia coli ECRC100 | 0.48 | OKFHMN_17755 | tldD | metalloprotease TldD | 0.33 | OKFHMN_14120 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 79 |
| Escherichia coli ECRC102 | 0.48 | NIAGMN_15515 | tldD | metalloprotease TldD | 0.33 | NIAGMN_11875 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 80 |
| Escherichia coli ECRC99 | 0.48 | KEDOAH_10395 | tldD | metalloprotease TldD | 0.33 | KEDOAH_14030 | hemN | oxygen-independent coproporphyrinogen III oxidase | — | — |
| Dickeya dianthicola ME23 | 0.48 | DZA65_RS01440 | | metalloprotease TldD | 0.32 | DZA65_RS22220 | | oxygen-independent coproporphyrinogen III oxidase | low | > 75 |
| Erwinia tracheiphila HP pepo 2.2 | 0.48 | IJEDHG_13595 | tldD | metalloprotease TldD | 0.33 | IJEDHG_08260 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 61 |
| Enterobacter asburiae PDN3 | 0.48 | EX28DRAFT_3295 | | Predicted Zn-dependent proteases and their inactivated homologs | 0.32 | EX28DRAFT_4348 | | oxygen-independent coproporphyrinogen III oxidase | low | > 76 |
| Erwinia tracheiphila SCR3 | 0.48 | LU632_RS21420 | tldD | metalloprotease TldD | 0.33 | LU632_RS22115 | hemN | oxygen-independent coproporphyrinogen III oxidase | low | > 73 |
| Rahnella sp. WP5 | 0.47 | EX31_RS12265 | | metalloprotease TldD | 0.32 | EX31_RS15885 | | oxygen-independent coproporphyrinogen III oxidase | 0.35 | 29 |
| Shewanella amazonensis SB2B | 0.47 | Sama_0474 | | TldD protein (RefSeq) | 0.34 | Sama_0086 | | coproporphyrinogen III oxidase (RefSeq) | low | > 62 |
| Parabacteroides merdae CL09T00C40 | 0.32 | HMPREF1078_RS03620 | | TldD/PmbA family protein | 0.28 | HMPREF1078_RS13395 | | oxygen-independent coproporphyrinogen III oxidase | low | > 61 |
| Synechocystis sp000284455 PCC 6803 | 0.22 | SGL_RS09635 | | TldD/PmbA family protein | 0.33 | SGL_RS10380 | | oxygen-independent coproporphyrinogen III oxidase | low | > 52 |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.08 | CA265_RS03855 | | TldD protein | 0.27 | CA265_RS01360 | | oxygen-independent coproporphyrinogen III oxidase | low | > 88 |
Not shown: 8 genomes with orthologs for MPMX19_00882 only; 8 genomes with orthologs for MPMX19_02313 only