Conservation of cofitness between HER17_RS04700 and HER17_RS12005 in Pectobacterium carotovorum WPP14

91 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS04700 glutamate 5-kinase 1.0 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.93 2
Rahnella sp. WP5 0.90 EX31_RS20980 glutamate 5-kinase 0.88 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.92 50
Serratia liquefaciens MT49 0.90 IAI46_04430 glutamate 5-kinase 0.91 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.79 6
Klebsiella michiganensis M5al 0.89 BWI76_RS05840 glutamate 5-kinase 0.86 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.59 77
Enterobacter sp. TBS_079 0.89 MPMX20_00927 Glutamate 5-kinase 0.85 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.83 55
Enterobacter asburiae PDN3 0.89 EX28DRAFT_2651 glutamate 5-kinase 0.85 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) — —
Pantoea sp. MT58 0.89 IAI47_15120 glutamate 5-kinase 0.82 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.82 61
Dickeya dianthicola 67-19 0.89 HGI48_RS16605 glutamate 5-kinase 0.90 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase low > 71
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.89 GFF4114 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.85 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) low > 78
Dickeya dianthicola ME23 0.88 DZA65_RS17695 glutamate 5-kinase 0.90 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase low > 75
Escherichia coli BW25113 0.88 b0242 proB gamma-glutamyl kinase (NCBI) 0.86 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 0.76 69
Escherichia coli ECRC98 0.88 JDDGAC_13300 proB Glutamate 5-kinase 0.86 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase low > 86
Escherichia coli ECRC100 0.88 OKFHMN_09675 proB Glutamate 5-kinase 0.86 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase low > 80
Escherichia coli ECOR27 0.88 NOLOHH_02050 proB Glutamate 5-kinase 0.86 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase low > 75
Escherichia coli Nissle 1917 0.88 ECOLIN_RS01825 glutamate 5-kinase 0.86 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.88 OHPLBJKB_03398 Glutamate 5-kinase 0.86 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) low > 73
Escherichia coli BL21 0.88 ECD_00239 gamma-glutamate kinase 0.86 ECD_00949 dihydro-orotate oxidase, FMN-linked low > 61
Escherichia coli ECRC62 0.88 BNILDI_00245 proB Glutamate 5-kinase 0.86 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase low > 75
Escherichia coli ECOR38 0.88 HEPCGN_07780 proB Glutamate 5-kinase 0.86 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase low > 87
Escherichia fergusonii Becca 0.88 EFB2_03778 Glutamate 5-kinase 0.86 EFB2_03126 Dihydroorotate dehydrogenase (quinone) low > 86
Escherichia coli ECRC99 0.88 KEDOAH_18480 proB Glutamate 5-kinase 0.86 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC101 0.88 MCAODC_00195 proB Glutamate 5-kinase 0.86 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 0.83 46
Erwinia tracheiphila SCR3 0.88 LU632_RS01185 proB glutamate 5-kinase 0.79 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase low > 74
Escherichia coli ECRC102 0.88 NIAGMN_07535 proB Glutamate 5-kinase 0.86 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Dickeya dadantii 3937 0.88 DDA3937_RS16535 glutamate 5-kinase 0.91 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.71 38
Vibrio cholerae E7946 ATCC 55056 0.64 CSW01_11575 glutamate 5-kinase 0.72 CSW01_07490 dihydroorotate dehydrogenase (quinone) low > 62
Shewanella loihica PV-4 0.62 Shew_2848 gamma-glutamyl kinase (RefSeq) 0.62 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) low > 60
Shewanella amazonensis SB2B 0.62 Sama_2516 gamma-glutamyl kinase (RefSeq) 0.64 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) low > 62
Shewanella sp. ANA-3 0.59 Shewana3_0954 gamma-glutamyl kinase (RefSeq) 0.64 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) low > 73
Shewanella oneidensis MR-1 0.59 SO1121 proB glutamate 5-kinase (NCBI ptt file) 0.63 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) low > 76
Dechlorosoma suillum PS 0.40 Dsui_0166 glutamate 5-kinase 0.55 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 — —
Pseudomonas fluorescens SBW25 0.39 PFLU_RS25360 glutamate 5-kinase 0.56 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.39 PFLU_RS25360 glutamate 5-kinase 0.56 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas simiae WCS417 0.39 PS417_23545 gamma-glutamyl kinase 0.56 PS417_20935 dihydroorotate dehydrogenase — —
Pseudomonas fluorescens FW300-N1B4 0.39 Pf1N1B4_2800 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.56 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens FW300-N2E3 0.37 AO353_14115 gamma-glutamyl kinase 0.55 AO353_00780 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.37 Psyr_0704 glutamate 5-kinase 0.56 Psyr_2106 dihydroorotate oxidase A — —
Pseudomonas syringae pv. syringae B728a 0.37 Psyr_0704 glutamate 5-kinase 0.56 Psyr_2106 dihydroorotate oxidase A — —
Paraburkholderia graminis OAS925 0.37 ABIE53_003588 glutamate 5-kinase 0.56 ABIE53_001954 dihydroorotate dehydrogenase — —
Burkholderia phytofirmans PsJN 0.37 BPHYT_RS17110 glutamate 5-kinase 0.56 BPHYT_RS08565 dihydroorotate dehydrogenase — —
Pseudomonas fluorescens GW456-L13 0.37 PfGW456L13_1472 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.55 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Paraburkholderia bryophila 376MFSha3.1 0.37 H281DRAFT_06264 glutamate 5-kinase 0.54 H281DRAFT_00743 dihydroorotate oxidase A — —
Paraburkholderia sabiae LMG 24235 0.37 QEN71_RS27270 glutamate 5-kinase 0.57 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.36 RALBFv3_RS06145 glutamate 5-kinase 0.55 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum UW163 0.36 UW163_RS07480 glutamate 5-kinase 0.55 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens FW300-N2E2 0.36 Pf6N2E2_5103 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.55 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_15815 gamma-glutamyl kinase 0.55 AO356_02610 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas putida KT2440 0.36 PP_0691 Glutamate 5-kinase 0.54 PP_2095 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas sp. RS175 0.36 PFR28_03769 Glutamate 5-kinase 0.56 PFR28_01054 Dihydroorotate dehydrogenase (quinone) — —
Variovorax sp. OAS795 0.36 ABID97_RS23400 glutamate 5-kinase 0.51 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase — —
Herbaspirillum seropedicae SmR1 0.36 HSERO_RS01815 gamma-glutamyl kinase 0.52 HSERO_RS16155 dihydroorotate dehydrogenase — —
Pseudomonas sp. S08-1 0.36 OH686_16305 Glutamate 5-kinase / RNA-binding C-terminal domain PUA 0.55 OH686_03120 dihydroorotate dehydrogenase (fumarate) — —
Azospirillum brasilense Sp245 0.36 AZOBR_RS04095 glutamate 5-kinase 0.38 AZOBR_RS13520 dihydroorotate dehydrogenase — —
Azospirillum sp. SherDot2 0.36 MPMX19_01933 Glutamate 5-kinase 0.37 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) — —
Cupriavidus basilensis FW507-4G11 0.36 RR42_RS17940 gamma-glutamyl kinase 0.55 RR42_RS07465 dihydroorotate dehydrogenase — —
Ralstonia solanacearum PSI07 0.35 RPSI07_RS11095 glutamate 5-kinase 0.54 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS01810 glutamate 5-kinase 0.56 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum GMI1000 0.35 RS_RS14095 glutamate 5-kinase 0.54 RS_RS08160 dihydroorotate dehydrogenase (quinone) — —
Castellaniella sp019104865 MT123 0.35 ABCV34_RS10800 glutamate 5-kinase 0.52 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas stutzeri RCH2 0.35 Psest_3384 glutamate 5-kinase 0.54 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 low > 67
Dinoroseobacter shibae DFL-12 0.35 Dshi_1467 glutamate 5-kinase (RefSeq) 0.33 Dshi_0847 Dihydroorotate oxidase (RefSeq) — —
Rhizobium sp. OAE497 0.34 ABIE40_RS18920 glutamate 5-kinase 0.39 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase — —
Magnetospirillum magneticum AMB-1 0.34 AMB_RS20630 glutamate 5-kinase 0.37 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase — —
Acidovorax sp. GW101-3H11 0.34 Ac3H11_4771 Glutamate 5-kinase (EC 2.7.2.11) 0.52 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF1274 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.51 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) low > 90
Sinorhizobium meliloti 1021 0.34 SMc03776 gamma-glutamyl kinase 0.39 SMc02245 dihydroorotate dehydrogenase 2 0.79 62
Agrobacterium fabrum C58 0.34 Atu2780 gamma-glutamyl kinase 0.42 Atu0486 dihydroorotate dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.34 TX73_000850 glutamate 5-kinase 0.37 TX73_004110 quinone-dependent dihydroorotate dehydrogenase — —
Acinetobacter radioresistens SK82 0.34 MPMX26_02135 Glutamate 5-kinase 0.55 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) low > 36
Caulobacter crescentus NA1000 Δfur 0.33 CCNA_00316 glutamate 5-kinase 0.33 CCNA_00562 dihydroorotate dehydrogenase low > 67
Caulobacter crescentus NA1000 0.33 CCNA_00316 glutamate 5-kinase 0.33 CCNA_00562 dihydroorotate dehydrogenase low > 66
Alteromonas macleodii MIT1002 0.33 MIT1002_04056 Glutamate 5-kinase 0.59 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) low > 70
Variovorax sp. SCN45 0.33 GFF2515 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.51 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) — —
Rhodospirillum rubrum S1H 0.33 Rru_A1239 Glutamate 5-kinase, ProB-related (NCBI) 0.38 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) 0.72 15
Marinobacter adhaerens HP15 0.33 HP15_508 gamma-glutamyl kinase 0.48 HP15_1377 dihydroorotate dehydrogenase — —
Bifidobacterium breve UCC2003 0.31 BBR_RS19445 glutamate 5-kinase 0.21 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase low > 34
Bosea sp. OAE506 0.31 ABIE41_RS07585 glutamate 5-kinase 0.34 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase — —
Phaeobacter inhibens DSM 17395 0.31 PGA1_c15510 glutamate 5-kinase ProB 0.34 PGA1_c12150 dihydroorotate dehydrogenase PyrD 0.80 15
Rhodanobacter denitrificans MT42 0.30 LRK55_RS02130 glutamate 5-kinase 0.48 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.30 LRK54_RS02375 glutamate 5-kinase 0.48 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.30 Xcc-8004.2326.1 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.47 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Rhodanobacter sp. FW510-T8 0.30 OKGIIK_09420 proB glutamate 5-kinase 0.48 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.30 A4249_RS16125 glutamate 5-kinase 0.37 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase — —
Mycobacterium tuberculosis H37Rv 0.29 Rv2439c Probable glutamate 5-kinase protein ProB (gamma-glutamyl kinase) (GK) 0.37 Rv2139 Probable dihydroorotate dehydrogenase PyrD — —
Lysobacter sp. OAE881 0.28 ABIE51_RS13370 glutamate 5-kinase 0.44 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.28 Echvi_4033 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.42 Echvi_1806 dihydroorotate dehydrogenase, subfamily 2 — —
Dyella japonica UNC79MFTsu3.2 0.28 ABZR86_RS08685 glutamate 5-kinase 0.49 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.27 ABZR88_RS22170 glutamate 5-kinase 0.41 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase — —
Pedobacter sp. GW460-11-11-14-LB5 0.27 CA265_RS20855 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.42 CA265_RS14005 dihydroorotate dehydrogenase (quinone) — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.26 CA264_07725 glutamate 5-kinase 0.41 CA264_00865 dihydroorotate dehydrogenase (quinone) low > 74
Bacteroides thetaiotaomicron VPI-5482 0.25 BT3719 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.25 BT1009 dihydroorotate dehydrogenase (NCBI ptt file) low > 81
Sphingomonas koreensis DSMZ 15582 0.21 Ga0059261_3512 glutamate 5-kinase (EC 2.7.2.11) (from data) 0.39 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) — —

Not shown: 8 genomes with orthologs for HER17_RS04700 only; 4 genomes with orthologs for HER17_RS12005 only