Conservation of cofitness between PGA1_c24870 and PGA1_c26470 in Phaeobacter inhibens DSM 17395

87 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Phaeobacter inhibens DSM 17395 1.0 PGA1_c24870 phosphoribosylaminoimidazole carboxylase ATPase subunit PurK 1.0 PGA1_c26470 2-isopropylmalate synthase LeuA 0.86 19
Dinoroseobacter shibae DFL-12 0.71 Dshi_0680 phosphoribosylaminoimidazole carboxylase, ATPase subunit (RefSeq) 0.78 Dshi_0596 2-isopropylmalate synthase (RefSeq) 0.76 14
Caulobacter crescentus NA1000 Δfur 0.51 CCNA_03392 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit 0.58 CCNA_01610 2-isopropylmalate synthase low > 67
Caulobacter crescentus NA1000 0.51 CCNA_03392 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit 0.58 CCNA_01610 2-isopropylmalate synthase low > 66
Agrobacterium fabrum C58 0.49 Atu3755 phosphoribosylaminoimidazole carboxylase ATPase subunit 0.12 Atu2264 2-isopropylmalate synthase 0.91 8
Bosea sp. OAE506 0.48 ABIE41_RS09245 5-(carboxyamino)imidazole ribonucleotide synthase 0.60 ABIE41_RS13000 2-isopropylmalate synthase low > 77
Rhodopseudomonas palustris CGA009 0.45 TX73_021645 5-(carboxyamino)imidazole ribonucleotide synthase 0.60 TX73_010545 2-isopropylmalate synthase — —
Magnetospirillum magneticum AMB-1 0.45 AMB_RS11140 5-(carboxyamino)imidazole ribonucleotide synthase 0.59 AMB_RS17765 2-isopropylmalate synthase — —
Sphingomonas koreensis DSMZ 15582 0.45 Ga0059261_1428 5-(carboxyamino)imidazole ribonucleotide synthase 0.10 Ga0059261_4031 2-isopropylmalate synthase, yeast type — —
Pseudomonas sp. RS175 0.37 PFR28_04495 N5-carboxyaminoimidazole ribonucleotide synthase 0.11 PFR28_00305 2-isopropylmalate synthase — —
Pseudomonas putida KT2440 0.37 PP_5335 N5-carboxyaminoimidazole ribonucleotide synthase 0.11 PP_1025 2-isopropylmalate synthase — —
Pseudomonas stutzeri RCH2 0.37 Psest_4068 phosphoribosylaminoimidazole carboxylase, PurK protein 0.51 Psest_1056 2-isopropylmalate synthase, bacterial type — —
Pseudomonas fluorescens FW300-N2E2 0.36 Pf6N2E2_4081 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.11 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) — —
Xanthomonas campestris pv. campestris strain 8004 0.36 Xcc-8004.2012.1 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.43 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) 0.69 42
Paraburkholderia bryophila 376MFSha3.1 0.36 H281DRAFT_04185 5-(carboxyamino)imidazole ribonucleotide synthase 0.48 H281DRAFT_04556 2-isopropylmalate synthase — —
Burkholderia phytofirmans PsJN 0.36 BPHYT_RS16245 phosphoribosylaminoimidazole carboxylase 0.48 BPHYT_RS06570 2-isopropylmalate synthase low > 109
Paraburkholderia graminis OAS925 0.36 ABIE53_003423 5-(carboxyamino)imidazole ribonucleotide synthase 0.48 ABIE53_001580 2-isopropylmalate synthase — —
Dechlorosoma suillum PS 0.36 Dsui_0091 phosphoribosylaminoimidazole carboxylase, PurK protein 0.51 Dsui_3519 2-isopropylmalate synthase, bacterial type — —
Lysobacter sp. OAE881 0.36 ABIE51_RS15390 5-(carboxyamino)imidazole ribonucleotide synthase 0.42 ABIE51_RS17570 2-isopropylmalate synthase low > 62
Paraburkholderia sabiae LMG 24235 0.36 QEN71_RS02450 5-(carboxyamino)imidazole ribonucleotide synthase 0.48 QEN71_RS24195 2-isopropylmalate synthase low > 153
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_11075 phosphoribosylaminoimidazole carboxylase 0.11 AO356_06550 2-isopropylmalate synthase — —
Pseudomonas sp. S08-1 0.35 OH686_13380 N5-carboxyaminoimidazole ribonucleotide synthase 0.12 OH686_17570 2-isopropylmalate synthase — —
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_747 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.10 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) — —
Marinobacter adhaerens HP15 0.35 HP15_2350 phosphoribosylaminoimidazole carboxylase ATPase subunit 0.50 HP15_538 2-isopropylmalate synthase — —
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_5047 5-(carboxyamino)imidazole ribonucleotide synthase 0.10 Psyr_1257 2-isopropylmalate synthase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_5047 5-(carboxyamino)imidazole ribonucleotide synthase 0.10 Psyr_1257 2-isopropylmalate synthase — —
Pseudomonas fluorescens FW300-N1B4 0.34 Pf1N1B4_2028 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.11 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) — —
Pseudomonas fluorescens SBW25 0.34 PFLU_RS29800 5-(carboxyamino)imidazole ribonucleotide synthase 0.10 PFLU_RS24765 2-isopropylmalate synthase — —
Pseudomonas simiae WCS417 0.34 PS417_28115 phosphoribosylaminoimidazole carboxylase 0.10 PS417_23110 2-isopropylmalate synthase — —
Pseudomonas fluorescens SBW25-INTG 0.34 PFLU_RS29800 5-(carboxyamino)imidazole ribonucleotide synthase 0.10 PFLU_RS24765 2-isopropylmalate synthase — —
Acinetobacter radioresistens SK82 0.34 MPMX26_03050 N5-carboxyaminoimidazole ribonucleotide synthase 0.10 MPMX26_00404 2-isopropylmalate synthase low > 36
Variovorax sp. SCN45 0.34 GFF5513 N5-carboxyaminoimidazole ribonucleotide synthase (EC 6.3.4.18) 0.48 GFF1165 2-isopropylmalate synthase (EC 2.3.3.13) low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF2770 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.48 GFF4281 2-isopropylmalate synthase (EC 2.3.3.13) — —
Rhodanobacter sp. FW510-T8 0.33 OKGIIK_03050 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 OKGIIK_13575 leuA 2-isopropylmalate synthase — —
Bifidobacterium breve UCC2003 0.33 BBR_RS13300 5-(carboxyamino)imidazole ribonucleotide synthase 0.11 BBR_RS11170 2-isopropylmalate synthase low > 34
Cupriavidus basilensis FW507-4G11 0.33 RR42_RS03230 phosphoribosylaminoimidazole carboxylase 0.46 RR42_RS05465 2-isopropylmalate synthase — —
Dyella japonica UNC79MFTsu3.2 0.32 ABZR86_RS09830 5-(carboxyamino)imidazole ribonucleotide synthase 0.42 ABZR86_RS15970 2-isopropylmalate synthase — —
Variovorax sp. OAS795 0.32 ABID97_RS01700 5-(carboxyamino)imidazole ribonucleotide synthase 0.48 ABID97_RS14910 2-isopropylmalate synthase — —
Acidovorax sp. GW101-3H11 0.32 Ac3H11_675 Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21) 0.47 Ac3H11_530 2-isopropylmalate synthase (EC 2.3.3.13) — —
Ralstonia solanacearum PSI07 0.32 RPSI07_RS21130 5-(carboxyamino)imidazole ribonucleotide synthase 0.47 RPSI07_RS14285 2-isopropylmalate synthase — —
Castellaniella sp019104865 MT123 0.32 ABCV34_RS00565 5-(carboxyamino)imidazole ribonucleotide synthase 0.13 ABCV34_RS12420 2-isopropylmalate synthase — —
Ralstonia solanacearum GMI1000 0.31 RS_RS02885 5-(carboxyamino)imidazole ribonucleotide synthase 0.47 RS_RS10395 2-isopropylmalate synthase — —
Ralstonia solanacearum UW163 0.31 UW163_RS01410 5-(carboxyamino)imidazole ribonucleotide synthase 0.47 UW163_RS10700 2-isopropylmalate synthase — —
Ralstonia solanacearum IBSBF1503 0.31 RALBFv3_RS12200 5-(carboxyamino)imidazole ribonucleotide synthase 0.47 RALBFv3_RS03025 2-isopropylmalate synthase — —
Rhodanobacter denitrificans MT42 0.31 LRK55_RS13530 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 LRK55_RS09985 2-isopropylmalate synthase low > 63
Ralstonia sp. UNC404CL21Col 0.31 ABZR87_RS08090 5-(carboxyamino)imidazole ribonucleotide synthase 0.47 ABZR87_RS14930 2-isopropylmalate synthase — —
Rhodanobacter denitrificans FW104-10B01 0.31 LRK54_RS13815 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 LRK54_RS10345 2-isopropylmalate synthase — —
Pantoea sp. MT58 0.30 IAI47_14355 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 IAI47_16000 2-isopropylmalate synthase 0.75 39
Escherichia coli ECOR27 0.29 NOLOHH_00830 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 NOLOHH_03060 2-isopropylmalate synthase low > 57
Escherichia coli Nissle 1917 0.29 ECOLIN_RS03025 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 ECOLIN_RS00400 2-isopropylmalate synthase low > 52
Escherichia coli BL21 0.29 ECD_00472 N5-carboxyaminoimidazole ribonucleotide synthase 0.40 ECD_00076 2-isopropylmalate synthase low > 60
Synechococcus elongatus PCC 7942 0.29 Synpcc7942_1428 purK phosphoribosylaminoimidazole carboxylase ATPase subunit 0.42 Synpcc7942_1410 leuA 2-isopropylmalate synthase — —
Escherichia fergusonii Becca 0.29 EFB2_03540 N5-carboxyaminoimidazole ribonucleotide synthase 0.40 EFB2_03971 2-isopropylmalate synthase low > 86
Escherichia coli ECOR38 0.29 HEPCGN_06480 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 HEPCGN_08695 2-isopropylmalate synthase low > 85
Escherichia coli ECRC62 0.29 BNILDI_22260 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 BNILDI_08550 2-isopropylmalate synthase — —
Escherichia coli ECRC101 0.28 MCAODC_27060 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 MCAODC_01230 2-isopropylmalate synthase — —
Escherichia coli ECRC98 0.28 JDDGAC_11490 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 JDDGAC_14310 2-isopropylmalate synthase — —
Escherichia coli ECRC102 0.28 NIAGMN_05895 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 NIAGMN_08565 2-isopropylmalate synthase — —
Escherichia coli ECRC101 0.28 OKFHMN_07840 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 OKFHMN_10715 2-isopropylmalate synthase — —
Escherichia coli ECRC99 0.28 KEDOAH_20130 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 KEDOAH_17440 2-isopropylmalate synthase — —
Escherichia coli BW25113 0.28 b0522 purK phosphoribosylaminoimidazole carboxylase (NCBI) 0.40 b0074 leuA 2-isopropylmalate synthase (NCBI) 0.76 57
Vibrio cholerae E7946 ATCC 55056 0.28 CSW01_00260 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 CSW01_12595 2-isopropylmalate synthase low > 62
Shewanella loihica PV-4 0.28 Shew_1249 phosphoribosylaminoimidazole carboxylase, ATPase subunit (RefSeq) 0.40 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.66 47
Enterobacter asburiae PDN3 0.28 EX28DRAFT_2460 phosphoribosylaminoimidazole carboxylase, PurK protein 0.39 EX28DRAFT_3670 2-isopropylmalate synthase (EC 2.3.3.13) — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.28 OHPLBJKB_03159 N5-carboxyaminoimidazole ribonucleotide synthase 0.40 OHPLBJKB_03583 2-isopropylmalate synthase low > 73
Rahnella sp. WP5 0.28 EX31_RS22620 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 EX31_RS03680 2-isopropylmalate synthase 0.92 23
Klebsiella michiganensis M5al 0.28 BWI76_RS07065 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 BWI76_RS04680 2-isopropylmalate synthase 0.79 27
Enterobacter sp. TBS_079 0.28 MPMX20_01097 N5-carboxyaminoimidazole ribonucleotide synthase 0.40 MPMX20_00769 2-isopropylmalate synthase 0.76 54
Erwinia tracheiphila SCR3 0.27 LU632_RS15250 purK 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 LU632_RS02880 leuA 2-isopropylmalate synthase low > 74
Alteromonas macleodii MIT1002 0.26 MIT1002_00522 N5-carboxyaminoimidazole ribonucleotide synthase 0.40 MIT1002_00949 2-isopropylmalate synthase 0.98 24
Serratia liquefaciens MT49 0.26 IAI46_05370 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 IAI46_03355 2-isopropylmalate synthase 0.69 44
Dickeya dianthicola 67-19 0.25 HGI48_RS15190 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 HGI48_RS18055 2-isopropylmalate synthase 0.71 14
Dickeya dianthicola ME23 0.25 DZA65_RS15995 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 DZA65_RS19200 2-isopropylmalate synthase 0.63 49
Shewanella oneidensis MR-1 0.25 SO3555 purK phosphoribosylaminoimidazole carboxylase, ATPase subunit (NCBI ptt file) 0.39 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.86 43
Dickeya dadantii 3937 0.25 DDA3937_RS15110 5-(carboxyamino)imidazole ribonucleotide synthase 0.41 DDA3937_RS18115 2-isopropylmalate synthase 0.77 20
Pectobacterium carotovorum WPP14 0.25 HER17_RS06470 5-(carboxyamino)imidazole ribonucleotide synthase 0.40 HER17_RS03085 2-isopropylmalate synthase 0.97 2
Shewanella amazonensis SB2B 0.25 Sama_1063 phosphoribosylaminoimidazole carboxylase ATPase subunit (RefSeq) 0.40 Sama_0335 2-isopropylmalate synthase (RefSeq) 0.79 62
Shewanella sp. ANA-3 0.24 Shewana3_3156 phosphoribosylaminoimidazole carboxylase ATPase subunit (RefSeq) 0.39 Shewana3_3761 2-isopropylmalate synthase (RefSeq) 0.86 34
Methanococcus maripaludis S2 0.19 MMP_RS00715 formate-dependent phosphoribosylglycinamide formyltransferase 0.33 MMP_RS05500 2-isopropylmalate synthase — —
Methanococcus maripaludis JJ 0.18 MMJJ_RS04770 formate-dependent phosphoribosylglycinamide formyltransferase 0.33 MMJJ_RS08870 2-isopropylmalate synthase low > 28
Desulfovibrio vulgaris Hildenborough JW710 0.17 DVU0723 purT phosphoribosylglycinamide formyltransferase 2 (TIGR) 0.45 DVU2981 leuA 2-isopropylmalate synthase (TIGR) low > 55
Phocaeicola dorei CL03T12C01 0.16 ABI39_RS14185 formate-dependent phosphoribosylglycinamide formyltransferase 0.41 ABI39_RS10195 2-isopropylmalate synthase low > 72
Desulfovibrio vulgaris Miyazaki F 0.16 DvMF_2756 purT phosphoribosylglycinamide formyltransferase 2 (RefSeq) 0.45 DvMF_1791 2-isopropylmalate synthase (RefSeq) 0.33 17
Phocaeicola vulgatus CL09T03C04 0.16 HMPREF1058_RS17920 formate-dependent phosphoribosylglycinamide formyltransferase 0.41 HMPREF1058_RS14545 2-isopropylmalate synthase low > 67
Bacteroides stercoris CC31F 0.15 HMPREF1181_RS16250 formate-dependent phosphoribosylglycinamide formyltransferase 0.40 HMPREF1181_RS14150 2-isopropylmalate synthase 0.46 54
Parabacteroides merdae CL09T00C40 0.15 HMPREF1078_RS10980 formate-dependent phosphoribosylglycinamide formyltransferase 0.41 HMPREF1078_RS16665 2-isopropylmalate synthase low > 61
Bacteroides thetaiotaomicron VPI-5482 0.15 BT0704 phosphoribosylglycinamide formyltransferase 2 (NCBI ptt file) 0.41 BT1861 2-isopropylmalate synthase (EC 2.3.3.13) (from data) 0.24 13
Bacteroides ovatus ATCC 8483 0.14 BACOVA_02411 phosphoribosylglycinamide formyltransferase 2 0.40 BACOVA_04604 2-isopropylmalate synthase low > 94

Not shown: 15 genomes with orthologs for PGA1_c24870 only; 0 genomes with orthologs for PGA1_c26470 only