Conservation of cofitness between CSW01_02430 and CSW01_17275 in Vibrio cholerae E7946 ATCC 55056

99 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02430 non-canonical purine NTP pyrophosphatase 1.0 CSW01_17275 large conductance mechanosensitive channel protein MscL 0.57 2
Escherichia coli ECRC102 0.66 NIAGMN_17005 rdgB XTP/dITP diphosphatase 0.68 NIAGMN_15280 mscL large-conductance mechanosensitive channel protein MscL
Escherichia coli ECRC98 0.66 JDDGAC_22870 rdgB XTP/dITP diphosphatase 0.68 JDDGAC_21140 mscL large-conductance mechanosensitive channel protein MscL low > 86
Escherichia coli ECRC99 0.66 KEDOAH_08900 rdgB XTP/dITP diphosphatase 0.68 KEDOAH_10630 mscL large-conductance mechanosensitive channel protein MscL
Escherichia coli ECRC100 0.66 OKFHMN_19240 rdgB XTP/dITP diphosphatase 0.67 OKFHMN_17510 mscL large-conductance mechanosensitive channel protein MscL low > 80
Escherichia coli Nissle 1917 0.66 ECOLIN_RS16430 XTP/dITP diphosphatase 0.69 ECOLIN_RS18885 large-conductance mechanosensitive channel protein MscL low > 55
Escherichia fergusonii Becca 0.66 EFB2_00948 dITP/XTP pyrophosphatase 0.69 EFB2_00533 Large-conductance mechanosensitive channel low > 86
Escherichia coli ECRC62 0.66 BNILDI_09690 rdgB XTP/dITP diphosphatase 0.68 BNILDI_02210 mscL large-conductance mechanosensitive channel protein MscL low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.66 OHPLBJKB_00762 dITP/XTP pyrophosphatase 0.68 OHPLBJKB_00413 Large-conductance mechanosensitive channel low > 73
Escherichia coli ECOR27 0.66 NOLOHH_11110 rdgB XTP/dITP diphosphatase 0.68 NOLOHH_09310 mscL large-conductance mechanosensitive channel protein MscL low > 75
Enterobacter asburiae PDN3 0.66 EX28DRAFT_2992 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.70 EX28DRAFT_0037 large conductance mechanosensitive channel protein low > 76
Escherichia coli BW25113 0.65 b2954 yggV putative deoxyribonucleotide triphosphate pyrophosphatase (NCBI) 0.68 b3291 mscL large-conductance mechanosensitive channel (NCBI) low > 76
Enterobacter sp. TBS_079 0.65 MPMX20_03812 dITP/XTP pyrophosphatase 0.60 MPMX20_04198 Large-conductance mechanosensitive channel low > 85
Escherichia coli ECOR38 0.65 HEPCGN_18545 rdgB XTP/dITP diphosphatase 0.68 HEPCGN_16340 mscL large-conductance mechanosensitive channel protein MscL low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.65 GFF3057 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.60 GFF2388 Large-conductance mechanosensitive channel low > 78
Escherichia coli BL21 0.65 ECD_02784 dITP/XTP pyrophosphatase 0.68 ECD_03141 mechanosensitive channel protein, high conductance
Rahnella sp. WP5 0.65 EX31_RS02705 XTP/dITP diphosphatase 0.69 EX31_RS15995 large-conductance mechanosensitive channel protein MscL low > 89
Escherichia coli ECRC101 0.65 MCAODC_09760 rdgB XTP/dITP diphosphatase 0.68 MCAODC_08040 mscL large-conductance mechanosensitive channel protein MscL low > 87
Klebsiella michiganensis M5al 0.65 BWI76_RS24115 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.71 BWI76_RS25690 large-conductance mechanosensitive channel low > 92
Serratia liquefaciens MT49 0.65 IAI46_21430 XTP/dITP diphosphatase 0.62 IAI46_23285 large-conductance mechanosensitive channel protein MscL low > 86
Dickeya dianthicola ME23 0.64 DZA65_RS18455 XTP/dITP diphosphatase 0.65 DZA65_RS20360 large-conductance mechanosensitive channel protein MscL low > 75
Pantoea sp. MT58 0.64 IAI47_03585 XTP/dITP diphosphatase 0.63 IAI47_02270 large-conductance mechanosensitive channel protein MscL low > 76
Dickeya dadantii 3937 0.64 DDA3937_RS17320 XTP/dITP diphosphatase 0.65 DDA3937_RS19145 large-conductance mechanosensitive channel protein MscL low > 74
Dickeya dianthicola 67-19 0.63 HGI48_RS17365 XTP/dITP diphosphatase 0.65 HGI48_RS19235 large-conductance mechanosensitive channel protein MscL low > 71
Erwinia amylovora T8 0.60 OLJFJH_08520 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.61 OLJFJH_03730 large-conductance mechanosensitive channel protein MscL low > 58
Kangiella aquimarina DSM 16071 0.60 B158DRAFT_0200 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.68 B158DRAFT_0905 large conductance mechanosensitive channel protein low > 40
Pectobacterium carotovorum WPP14 0.59 HER17_RS03790 XTP/dITP diphosphatase 0.68 HER17_RS02205 large-conductance mechanosensitive channel protein MscL low > 75
Shewanella sp. ANA-3 0.59 Shewana3_1189 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase (RefSeq) 0.96 Shewana3_0520 mscL large-conductance mechanosensitive channel (RefSeq) low > 73
Shewanella oneidensis MR-1 0.58 SO3358 HAM1 protein (NCBI ptt file) 0.95 SO0522 mscL large conductance mechanosensitive channel protein (NCBI ptt file) low > 76
Pseudomonas syringae pv. syringae B728a ΔmexB 0.54 Psyr_0472 Ham1-like protein 0.75 Psyr_4276 Large-conductance mechanosensitive channel low > 86
Pseudomonas syringae pv. syringae B728a 0.54 Psyr_0472 Ham1-like protein 0.75 Psyr_4276 Large-conductance mechanosensitive channel low > 86
Rhodanobacter sp000427505 FW510-R12 0.53 LRK53_RS16800 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.46 LRK53_RS16605 large-conductance mechanosensitive channel protein MscL low > 60
Rhodanobacter sp. FW510-T8 0.53 OKGIIK_12155 rdgB RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.44 OKGIIK_11965 mscL large-conductance mechanosensitive channel protein MscL low > 52
Pseudomonas fluorescens FW300-N2C3 0.53 AO356_13395 non-canonical purine NTP pyrophosphatase 0.78 AO356_15665 large-conductance mechanosensitive channel low > 104
Pseudomonas sp. RS175 0.53 PFR28_04248 dITP/XTP pyrophosphatase 0.79 PFR28_03795 Large-conductance mechanosensitive channel low > 88
Pseudomonas sp. SVBP6 0.52 COO64_RS12970 rdgB RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.76 COO64_RS02915 mscL large-conductance mechanosensitive channel protein MscL low > 93
Pseudomonas fluorescens FW300-N2E2 0.52 Pf6N2E2_4594 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.78 Pf6N2E2_5073 Large-conductance mechanosensitive channel low > 103
Pseudomonas simiae WCS417 0.52 PS417_26755 nucleoside-triphosphate diphosphatase 0.77 PS417_24320 large-conductance mechanosensitive channel low > 88
Pseudomonas sp. DMC3 0.52 GFF215 dITP/XTP pyrophosphatase 0.78 GFF3951 Large-conductance mechanosensitive channel
Pseudomonas putida KT2440 0.52 PP_5100 dITP/XTP pyrophosphatase 0.76 PP_4645 Large-conductance mechanosensitive channel low > 96
Xanthomonas campestris pv. campestris strain 8004 0.52 Xcc-8004.1223.1 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.53 Xcc-8004.1277.1 Large-conductance mechanosensitive channel
Pseudomonas aeruginosa PA14 0.52 IKLFDK_23490 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.78 IKLFDK_00440 large-conductance mechanosensitive channel protein MscL low > 101
Pseudomonas sp. BP01 0.52 JOY50_RS20880 rdgB RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.74 JOY50_RS15690 mscL large-conductance mechanosensitive channel protein MscL 0.39 21
Paraburkholderia sabiae LMG 24235 0.51 QEN71_RS03640 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.39 QEN71_RS22080 large conductance mechanosensitive channel protein MscL low > 153
Pseudomonas fluorescens SBW25 0.51 PFLU_RS28400 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.77 PFLU_RS26245 large-conductance mechanosensitive channel protein MscL low > 109
Paraburkholderia bryophila 376MFSha3.1 0.51 H281DRAFT_04009 XTP/dITP diphosphohydrolase 0.38 H281DRAFT_00877 large conductance mechanosensitive channel low > 103
Pseudomonas fluorescens FW300-N2E3 0.51 AO353_08195 non-canonical purine NTP pyrophosphatase 0.77 AO353_13965 large-conductance mechanosensitive channel low > 101
Pseudomonas fluorescens SBW25-INTG 0.51 PFLU_RS28400 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.77 PFLU_RS26245 large-conductance mechanosensitive channel protein MscL low > 109
Lysobacter sp. OAE881 0.51 ABIE51_RS17295 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.41 ABIE51_RS16585 large-conductance mechanosensitive channel protein MscL low > 62
Pseudomonas fluorescens GW456-L13 0.51 PfGW456L13_1004 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.75 PfGW456L13_1441 Large-conductance mechanosensitive channel low > 87
Pseudomonas fluorescens FW300-N1B4 0.51 Pf1N1B4_2335 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.76 Pf1N1B4_2765 Large-conductance mechanosensitive channel low > 87
Paraburkholderia graminis OAS925 0.51 ABIE53_003235 XTP/dITP diphosphohydrolase 0.37 ABIE53_002092 large conductance mechanosensitive channel low > 113
Burkholderia phytofirmans PsJN 0.50 BPHYT_RS15330 nucleoside-triphosphate diphosphatase 0.38 BPHYT_RS09275 large-conductance mechanosensitive channel
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS11905 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.49 ABZR86_RS11735 large-conductance mechanosensitive channel protein MscL low > 74
Pseudomonas stutzeri RCH2 0.50 Psest_0277 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family 0.67 Psest_3398 large conductance mechanosensitive channel protein low > 67
Pseudomonas sp. S08-1 0.50 OH686_11015 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.69 OH686_16155 large conductance mechanosensitive channel protein low > 80
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS11740 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.45 LRK54_RS11920 large-conductance mechanosensitive channel protein MscL
Rhodanobacter denitrificans MT42 0.49 LRK55_RS11465 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.45 LRK55_RS11645 large-conductance mechanosensitive channel protein MscL
Herbaspirillum seropedicae SmR1 0.48 HSERO_RS10660 nucleoside-triphosphate diphosphatase 0.41 HSERO_RS20250 large conductance mechanosensitive channel protein MscL low > 78
Acinetobacter radioresistens SK82 0.48 MPMX26_00400 dITP/XTP pyrophosphatase 0.47 MPMX26_02488 Large-conductance mechanosensitive channel low > 36
Methylophilus sp. DMC18 0.46 GFF2137 dITP/XTP pyrophosphatase 0.40 GFF823 Large-conductance mechanosensitive channel low > 43
Ralstonia solanacearum UW163 0.45 UW163_RS10370 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.40 UW163_RS06880 large conductance mechanosensitive channel protein MscL
Ralstonia solanacearum IBSBF1503 0.45 RALBFv3_RS03350 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.40 RALBFv3_RS06735 large conductance mechanosensitive channel protein MscL low > 76
Ralstonia sp. UNC404CL21Col 0.45 ABZR87_RS15260 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.42 ABZR87_RS02390 large conductance mechanosensitive channel protein MscL low > 80
Ralstonia solanacearum PSI07 0.44 RPSI07_RS13835 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.40 RPSI07_RS10500 large conductance mechanosensitive channel protein MscL
Castellaniella sp019104865 MT123 0.44 ABCV34_RS03520 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.36 ABCV34_RS12640 large conductance mechanosensitive channel protein MscL
Ralstonia solanacearum GMI1000 0.43 RS_RS10835 non-canonical purine NTP pyrophosphatase 0.40 RS_RS14680 large conductance mechanosensitive channel protein MscL
Cupriavidus basilensis FW507-4G11 0.43 RR42_RS04885 nucleoside-triphosphate diphosphatase 0.42 RR42_RS18830 large-conductance mechanosensitive channel low > 128
Desulfovibrio vulgaris Miyazaki F 0.43 DvMF_1699 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family (RefSeq) 0.43 DvMF_2606 large conductance mechanosensitive channel protein (RefSeq)
Hydrogenophaga sp. GW460-11-11-14-LB1 0.38 GFF3255 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.43 GFF1296 Large-conductance mechanosensitive channel low > 90
Synechococcus elongatus PCC 7942 0.37 Synpcc7942_1266 rdgB Ham1-like protein 0.32 Synpcc7942_1991 mscL large conductance mechanosensitive channel protein low > 38
Variovorax sp. SCN45 0.36 GFF2382 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.66) 0.46 GFF5369 Large-conductance mechanosensitive channel low > 127
Variovorax sp. OAS795 0.35 ABID97_RS23635 non-canonical purine NTP pyrophosphatase 0.46 ABID97_RS23050 large conductance mechanosensitive channel protein MscL low > 91
Acidovorax sp. GW101-3H11 0.35 Ac3H11_3671 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.41 Ac3H11_4748 Large-conductance mechanosensitive channel
Caulobacter crescentus NA1000 0.34 CCNA_00145 xanthosine triphosphate pyrophosphatase 0.42 CCNA_03700 large-conductance mechanosensitive channel low > 66
Caulobacter crescentus NA1000 Δfur 0.34 CCNA_00145 xanthosine triphosphate pyrophosphatase 0.42 CCNA_03700 large-conductance mechanosensitive channel low > 67
Sphingomonas koreensis DSMZ 15582 0.33 Ga0059261_2742 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.38 Ga0059261_2131 large conductance mechanosensitive channel protein low > 68
Agrobacterium fabrum C58 0.32 Atu0326 putative deoxyribonucleotide triphosphate pyrophosphatase 0.45 Atu0528 large conductance mechanosensitive channel protein
Mycobacterium tuberculosis H37Rv 0.31 Rv1341 Conserved protein 0.24 Rv0985c Possible large-conductance ion mechanosensitive channel MscL
Brevundimonas sp. GW460-12-10-14-LB2 0.31 A4249_RS12440 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.46 A4249_RS10890 large-conductance mechanosensitive channel protein MscL
Phaeobacter inhibens DSM 17395 0.31 PGA1_c35040 nucleoside-triphosphatase RdgB 0.43 PGA1_c07090 large-conductance mechanosensitive channel low > 62
Mucilaginibacter yixingensis YX-36 DSM 26809 0.30 ABZR88_RS21980 non-canonical purine NTP diphosphatase 0.56 ABZR88_RS14575 large-conductance mechanosensitive channel protein MscL
Sinorhizobium meliloti 1021 0.30 SMc01146 deoxyribonucleotide triphosphate pyrophosphatase 0.38 SMc02250 large-conductance mechanosensitive channel low > 103
Rhizobium sp. OAE497 0.29 ABIE40_RS01630 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.43 ABIE40_RS02640 large conductance mechanosensitive channel protein MscL low > 107
Pedobacter sp. GW460-11-11-14-LB5 0.29 CA265_RS24990 non-canonical purine NTP pyrophosphatase 0.48 CA265_RS11000 large-conductance mechanosensitive channel 0.24 30
Bosea sp. OAE506 0.29 ABIE41_RS03300 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.51 ABIE41_RS22180 large conductance mechanosensitive channel protein MscL low > 77
Echinicola vietnamensis KMM 6221, DSM 17526 0.29 Echvi_1180 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family 0.61 Echvi_2306 large conductance mechanosensitive channel protein low > 79
Dinoroseobacter shibae DFL-12 0.29 Dshi_3462 Ham1 family protein (RefSeq) 0.39 Dshi_0241 large conductance mechanosensitive channel protein (RefSeq) low > 64
Phocaeicola dorei CL03T12C01 0.28 ABI39_RS05750 non-canonical purine NTP diphosphatase 0.55 ABI39_RS17980 large-conductance mechanosensitive channel protein MscL 0.35 68
Cellulophaga baltica 18 0.28 M666_RS17985 non-canonical purine NTP diphosphatase 0.41 M666_RS17310 large conductance mechanosensitive channel protein MscL low > 67
Parabacteroides merdae CL09T00C40 0.27 HMPREF1078_RS06565 non-canonical purine NTP diphosphatase 0.57 HMPREF1078_RS10535 large-conductance mechanosensitive channel protein MscL low > 61
Phocaeicola vulgatus CL09T03C04 0.27 HMPREF1058_RS11235 non-canonical purine NTP diphosphatase 0.54 HMPREF1058_RS06045 large-conductance mechanosensitive channel protein MscL low > 67
Bacteroides stercoris CC31F 0.27 HMPREF1181_RS01925 non-canonical purine NTP diphosphatase 0.52 HMPREF1181_RS06140 large-conductance mechanosensitive channel protein MscL low > 56
Azospirillum sp. SherDot2 0.27 MPMX19_02575 dITP/XTP pyrophosphatase 0.49 MPMX19_00116 Large-conductance mechanosensitive channel low > 112
Azospirillum brasilense Sp245 0.27 AZOBR_RS02200 nucleoside-triphosphate diphosphatase 0.45 AZOBR_RS02870 mechanosensitive ion channel protein MscL low > 97
Rhodopseudomonas palustris CGA009 0.26 TX73_001705 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.49 TX73_013925 large conductance mechanosensitive channel protein MscL low > 86
Xanthobacter sp. DMC5 0.26 GFF1892 dITP/XTP pyrophosphatase 0.47 GFF4315 Large-conductance mechanosensitive channel
Pontibacter actiniarum KMM 6156, DSM 19842 0.25 CA264_19890 non-canonical purine NTP pyrophosphatase 0.49 CA264_14480 large-conductance mechanosensitive channel low > 74
Bacteroides thetaiotaomicron VPI-5482 0.25 BT3128 putative xanthosine triphosphate pyrophosphatase (NCBI ptt file) 0.52 BT4264 putative ion channel (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.25 BACOVA_02837 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.52 BACOVA_05097 large conductance mechanosensitive channel protein low > 94

Not shown: 13 genomes with orthologs for CSW01_02430 only; 1 genomes with orthologs for CSW01_17275 only