Conservation of cofitness between CSW01_03980 and CSW01_12680 in Vibrio cholerae E7946 ATCC 55056

101 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_03980 IMP dehydrogenase 1.0 CSW01_12680 cytosol aminopeptidase 0.92 9
Shewanella sp. ANA-3 0.78 Shewana3_1235 inosine 5'-monophosphate dehydrogenase (RefSeq) 0.81 Shewana3_3006 leucyl aminopeptidase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.77 SO3293 guaB inosine-5'-monophosphate dehydrogenase (NCBI ptt file) 0.81 SO1368 pepA-2 cytosol aminopeptidase (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.77 Sama_2359 inosine 5'-monophosphate dehydrogenase (RefSeq) 0.81 Sama_0795 leucyl aminopeptidase (RefSeq) — —
Pectobacterium carotovorum WPP14 0.77 HER17_RS06155 IMP dehydrogenase 0.81 HER17_RS19450 leucyl aminopeptidase low > 75
Serratia liquefaciens MT49 0.77 IAI46_19210 IMP dehydrogenase 0.83 IAI46_02360 leucyl aminopeptidase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.77 GFF2160 'Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain' transl_table=11 0.82 GFF949 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 78
Pantoea sp. MT58 0.77 IAI47_05105 IMP dehydrogenase 0.83 IAI47_16795 leucyl aminopeptidase — —
Klebsiella pneumoniae MKP103 0.77 KDGMDA_28160 IMP dehydrogenase 0.81 KDGMDA_11530 leucyl aminopeptidase 0.40 74
Pantoea agglomerans CFBP13505 P0401 0.77 PagCFBP13505_RS14995 IMP dehydrogenase 0.83 PagCFBP13505_RS08910 leucyl aminopeptidase — —
Klebsiella michiganensis M5al 0.76 BWI76_RS21030 IMP dehydrogenase 0.81 BWI76_RS03040 leucyl aminopeptidase — —
Shewanella loihica PV-4 0.76 Shew_1297 inositol-5-monophosphate dehydrogenase (RefSeq) 0.81 Shew_0939 leucyl aminopeptidase (RefSeq) — —
Erwinia tracheiphila HP pepo 2.2 0.76 IJEDHG_02725 guaB IMP dehydrogenase 0.84 IJEDHG_14170 pepA leucyl aminopeptidase — —
Erwinia tracheiphila SCR3 0.76 LU632_RS17755 guaB IMP dehydrogenase 0.84 LU632_RS20855 pepA leucyl aminopeptidase — —
Rahnella sp. WP5 0.76 EX31_RS20450 IMP dehydrogenase 0.83 EX31_RS04385 leucyl aminopeptidase low > 89
Dickeya dianthicola 67-19 0.76 HGI48_RS15535 IMP dehydrogenase 0.83 HGI48_RS01955 leucyl aminopeptidase low > 71
Dickeya dianthicola ME23 0.76 DZA65_RS16610 IMP dehydrogenase 0.83 DZA65_RS02060 leucyl aminopeptidase low > 75
Enterobacter asburiae PDN3 0.76 EX28DRAFT_0139 inosine-5'-monophosphate dehydrogenase 0.82 EX28DRAFT_3267 Leucyl aminopeptidase — —
Dickeya dadantii 3937 0.76 DDA3937_RS15420 IMP dehydrogenase 0.83 DDA3937_RS01995 leucyl aminopeptidase low > 74
Enterobacter sp. TBS_079 0.76 MPMX20_03382 Inosine-5'-monophosphate dehydrogenase 0.82 MPMX20_04118 Cytosol aminopeptidase low > 85
Escherichia coli Nissle 1917 0.75 ECOLIN_RS14240 IMP dehydrogenase 0.82 ECOLIN_RS24695 leucyl aminopeptidase low > 55
Escherichia coli ECOR27 0.75 NOLOHH_13410 guaB IMP dehydrogenase 0.82 NOLOHH_04055 pepA leucyl aminopeptidase low > 76
Escherichia fergusonii Becca 0.75 EFB2_01385 Inosine-5'-monophosphate dehydrogenase 0.82 EFB2_04275 Cytosol aminopeptidase low > 86
Escherichia coli ECRC62 0.75 BNILDI_12210 guaB IMP dehydrogenase 0.82 BNILDI_07455 pepA leucyl aminopeptidase low > 75
Escherichia coli ECRC100 0.75 OKFHMN_21760 guaB IMP dehydrogenase 0.82 OKFHMN_11790 pepA leucyl aminopeptidase low > 79
Escherichia coli BL21 0.75 ECD_02400 IMP dehydrogenase 0.82 ECD_04126 multifunctional aminopeptidase A: a cyteinylglycinase, transcription regulator and site-specific recombination factor low > 61
Escherichia coli ECOR38 0.75 HEPCGN_20900 guaB IMP dehydrogenase 0.82 HEPCGN_09980 pepA leucyl aminopeptidase low > 88
Escherichia coli ECRC99 0.75 KEDOAH_06460 guaB IMP dehydrogenase 0.82 KEDOAH_16360 pepA leucyl aminopeptidase — —
Escherichia coli ECRC102 0.75 NIAGMN_19530 guaB IMP dehydrogenase 0.82 NIAGMN_09640 pepA leucyl aminopeptidase low > 80
Escherichia coli ECRC98 0.75 JDDGAC_25435 guaB IMP dehydrogenase 0.82 JDDGAC_15430 pepA leucyl aminopeptidase low > 87
Escherichia coli BW25113 0.75 b2508 guaB inositol-5-monophosphate dehydrogenase (NCBI) 0.82 b4260 pepA leucyl aminopeptidase (NCBI) — —
Escherichia coli ECRC101 0.75 MCAODC_12290 guaB IMP dehydrogenase 0.82 MCAODC_02295 pepA leucyl aminopeptidase low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.75 OHPLBJKB_01201 'Inosine-5'-monophosphate dehydrogenase' transl_table=11 0.82 OHPLBJKB_03776 Cytosol aminopeptidase 0.46 36
Erwinia amylovora T8 0.73 OLJFJH_10500 IMP dehydrogenase 0.84 OLJFJH_07380 leucyl aminopeptidase low > 58
Alteromonas macleodii MIT1002 0.71 MIT1002_02779 Inosine-5'-monophosphate dehydrogenase 0.79 MIT1002_03197 Cytosol aminopeptidase — —
Kangiella aquimarina DSM 16071 0.70 B158DRAFT_1158 inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) 0.60 B158DRAFT_1167 Leucyl aminopeptidase — —
Pseudomonas segetis P6 0.68 MPMX49_01540 Inosine-5'-monophosphate dehydrogenase 0.53 MPMX49_03516 Cytosol aminopeptidase — —
Methylophilus sp. DMC18 0.66 GFF1138 Inosine-5'-monophosphate dehydrogenase 0.49 GFF1514 Cytosol aminopeptidase — —
Pseudomonas fluorescens FW300-N2C3 0.65 AO356_06525 inosine-5'-monophosphate dehydrogenase 0.54 AO356_17470 aminopeptidase — —
Pseudomonas sp. DMC3 0.65 GFF4327 Inosine-5'-monophosphate dehydrogenase 0.54 GFF1952 Cytosol aminopeptidase — —
Pseudomonas sp. S08-1 0.65 OH686_17590 inosine-5'-monophosphate dehydrogenase 0.52 OH686_07810 Cytosol aminopeptidase PepA — —
Pseudomonas sp. RS175 0.65 PFR28_00310 'Inosine-5'-monophosphate dehydrogenase' transl_table=11 0.53 PFR28_03528 Cytosol aminopeptidase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.65 Psyr_1261 inosine-5'-monophosphate dehydrogenase 0.54 Psyr_1091 aminopeptidase A, Metallo peptidase, MEROPS family M17 — —
Pseudomonas fluorescens FW300-N2E2 0.65 Pf6N2E2_3165 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain 0.54 Pf6N2E2_5420 Cytosol aminopeptidase PepA (EC 3.4.11.1) — —
Pseudomonas syringae pv. syringae B728a 0.65 Psyr_1261 inosine-5'-monophosphate dehydrogenase 0.54 Psyr_1091 aminopeptidase A, Metallo peptidase, MEROPS family M17 — —
Pseudomonas fluorescens FW300-N1B4 0.64 Pf1N1B4_840 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain 0.54 Pf1N1B4_898 Cytosol aminopeptidase PepA (EC 3.4.11.1) — —
Pseudomonas fluorescens FW300-N2E3 0.64 AO353_15950 inosine-5'-monophosphate dehydrogenase 0.54 AO353_04535 aminopeptidase — —
Marinobacter adhaerens HP15 0.64 HP15_2051 inositol-5-monophosphate dehydrogenase 0.46 HP15_1315 leucyl aminopeptidase — —
Pseudomonas sp. BP01 0.64 JOY50_RS11500 guaB IMP dehydrogenase 0.52 JOY50_RS11265 leucyl aminopeptidase — —
Pseudomonas fluorescens SBW25 0.64 PFLU_RS24735 IMP dehydrogenase 0.54 PFLU_RS05235 leucyl aminopeptidase — —
Pseudomonas fluorescens SBW25-INTG 0.64 PFLU_RS24735 IMP dehydrogenase 0.54 PFLU_RS05235 leucyl aminopeptidase — —
Pseudomonas putida KT2440 0.64 PP_1031 IMP dehydrogenase and single strand DNA binding factor 0.52 PP_0980 Probable cytosol aminopeptidase — —
Pseudomonas simiae WCS417 0.64 PS417_23075 inosine-5-monophosphate dehydrogenase 0.54 PS417_05165 cytosol aminopeptidase — —
Paraburkholderia sabiae LMG 24235 0.64 QEN71_RS06540 IMP dehydrogenase 0.51 QEN71_RS25205 leucyl aminopeptidase — —
Pseudomonas orientalis W4I3 0.64 QF045_RS25300 IMP dehydrogenase 0.54 QF045_RS08155 leucyl aminopeptidase — —
Pseudomonas stutzeri RCH2 0.64 Psest_1286 inosine-5'-monophosphate dehydrogenase 0.51 Psest_1235 Leucyl aminopeptidase — —
Dyella japonica UNC79MFTsu3.2 0.64 ABZR86_RS05410 IMP dehydrogenase 0.42 ABZR86_RS19105 leucyl aminopeptidase — —
Ralstonia solanacearum PSI07 0.63 RPSI07_RS16975 IMP dehydrogenase 0.49 RPSI07_RS12825 leucyl aminopeptidase — —
Pseudomonas lactucae CFBP13502 0.63 GEMAOFIL_04768 'Inosine-5'-monophosphate dehydrogenase' transl_table=11 0.54 GEMAOFIL_01239 Cytosol aminopeptidase — —
Ralstonia solanacearum UW163 0.63 UW163_RS13845 IMP dehydrogenase 0.48 UW163_RS09120 leucyl aminopeptidase — —
Pseudomonas fluorescens GW456-L13 0.63 PfGW456L13_4818 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain 0.54 PfGW456L13_4846 Cytosol aminopeptidase PepA (EC 3.4.11.1) — —
Ralstonia solanacearum IBSBF1503 0.63 RALBFv3_RS00515 IMP dehydrogenase 0.48 RALBFv3_RS04550 leucyl aminopeptidase — —
Paraburkholderia graminis OAS925 0.63 ABIE53_002478 IMP dehydrogenase 0.51 ABIE53_001235 leucyl aminopeptidase — —
Ralstonia solanacearum GMI1000 0.63 RS_RS07170 IMP dehydrogenase 0.47 RS_RS12120 cytosol aminopeptidase — —
Dechlorosoma suillum PS 0.63 Dsui_2671 inosine-5''-monophosphate dehydrogenase 0.59 Dsui_3536 leucyl aminopeptidase — —
Rhodanobacter denitrificans FW104-10B01 0.63 LRK54_RS00105 IMP dehydrogenase 0.44 LRK54_RS12375 leucyl aminopeptidase — —
Pseudomonas sp. SVBP6 0.63 COO64_RS04660 guaB IMP dehydrogenase 0.51 COO64_RS04415 leucyl aminopeptidase — —
Paraburkholderia bryophila 376MFSha3.1 0.63 H281DRAFT_00634 inosine-5'-monophosphate dehydrogenase 0.51 H281DRAFT_00123 aminopeptidase A. Metallo peptidase. MEROPS family M17 — —
Herbaspirillum seropedicae SmR1 0.62 HSERO_RS11015 inosine 5'-monophosphate dehydrogenase 0.46 HSERO_RS15600 cytosol aminopeptidase — —
Rhodanobacter denitrificans MT42 0.62 LRK55_RS18100 IMP dehydrogenase 0.44 LRK55_RS12110 leucyl aminopeptidase — —
Rhodanobacter sp. FW510-T8 0.62 OKGIIK_07095 guaB IMP dehydrogenase 0.43 OKGIIK_11560 pepB leucyl aminopeptidase — —
Rhodanobacter sp000427505 FW510-R12 0.62 LRK53_RS11160 IMP dehydrogenase 0.45 LRK53_RS16125 leucyl aminopeptidase — —
Burkholderia phytofirmans PsJN 0.62 BPHYT_RS12020 inosine 5'-monophosphate dehydrogenase 0.51 BPHYT_RS04795 cytosol aminopeptidase — —
Dinoroseobacter shibae DFL-12 0.62 Dshi_1646 inosine-5'-monophosphate dehydrogenase (RefSeq) 0.25 Dshi_1191 Leucyl aminopeptidase (RefSeq) low > 64
Hydrogenophaga sp. GW460-11-11-14-LB1 0.62 GFF4356 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) 0.36 GFF4309 Cytosol aminopeptidase PepA (EC 3.4.11.1) — —
Cupriavidus basilensis FW507-4G11 0.62 RR42_RS11750 inosine-5-monophosphate dehydrogenase 0.48 RR42_RS16225 cytosol aminopeptidase — —
Acidovorax sp. GW101-3H11 0.62 Ac3H11_2857 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) 0.36 Ac3H11_2399 Cytosol aminopeptidase PepA (EC 3.4.11.1) — —
Ralstonia sp. UNC404CL21Col 0.61 ABZR87_RS11965 IMP dehydrogenase 0.50 ABZR87_RS00150 leucyl aminopeptidase — —
Acinetobacter baumannii LAC-4 0.61 RR41_RS00905 IMP dehydrogenase 0.38 RR41_RS17825 leucyl aminopeptidase — —
Xanthomonas campestris pv. campestris strain 8004 0.61 Xcc-8004.2391.1 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain 0.44 Xcc-8004.4446.1 Cytosol aminopeptidase PepA (EC 3.4.11.1) — —
Azospirillum sp. SherDot2 0.61 MPMX19_01690 Inosine-5'-monophosphate dehydrogenase 0.27 MPMX19_01593 Cytosol aminopeptidase — —
Variovorax sp. SCN45 0.61 GFF209 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain 0.36 GFF240 Cytosol aminopeptidase PepA (EC 3.4.11.1) — —
Pseudomonas aeruginosa MRSN321 0.61 DY961_RS14075 guaB;go_function=IMP IMP dehydrogenase 0.52 DY961_RS13735 leucyl aminopeptidase — —
Pseudomonas aeruginosa PA14 0.61 IKLFDK_19415 IMP dehydrogenase 0.51 IKLFDK_19730 leucyl aminopeptidase — —
Pseudomonas aeruginosa PUPa3 0.61 DQ20_RS43025 guaB;go_function=IMP IMP dehydrogenase 0.52 DQ20_RS49000 leucyl aminopeptidase — —
Castellaniella sp019104865 MT123 0.61 ABCV34_RS04905 IMP dehydrogenase 0.43 ABCV34_RS08295 leucyl aminopeptidase — —
Variovorax sp. OAS795 0.60 ABID97_RS16415 IMP dehydrogenase 0.37 ABID97_RS16580 leucyl aminopeptidase — —
Azospirillum brasilense Sp245 0.60 AZOBR_RS16110 inosine-5`-monophosphate dehydrogenase 0.29 AZOBR_RS16385 aminopeptidase A — —
Lysobacter sp. OAE881 0.59 ABIE51_RS09475 IMP dehydrogenase 0.46 ABIE51_RS04475 leucyl aminopeptidase — —
Magnetospirillum magneticum AMB-1 0.59 AMB_RS19150 IMP dehydrogenase 0.32 AMB_RS18600 leucyl aminopeptidase — —
Rhodopseudomonas palustris CGA009 0.56 TX73_011355 IMP dehydrogenase 0.25 TX73_015830 leucyl aminopeptidase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.56 A4249_RS03025 IMP dehydrogenase 0.30 A4249_RS06730 leucyl aminopeptidase — —
Bosea sp. OAE506 0.56 ABIE41_RS15185 IMP dehydrogenase 0.27 ABIE41_RS17710 leucyl aminopeptidase low > 77
Fusobacterium nucleatum SB010 0.56 HUW76_04090 IMP dehydrogenase 0.27 HUW76_01625 leucyl aminopeptidase — —
Desulfovibrio vulgaris Hildenborough JW710 0.55 DVU1044 guaB inosine-5`-monophosphate dehydrogenase (TIGR) 0.28 DVU0415 pepA cytosol aminopeptidase (TIGR) — —
Caulobacter crescentus NA1000 Δfur 0.55 CCNA_01689 inosine-5'-monophosphate dehydrogenase 0.31 CCNA_01763 multifunctional aminopeptidase — —
Caulobacter crescentus NA1000 0.55 CCNA_01689 inosine-5'-monophosphate dehydrogenase 0.31 CCNA_01763 multifunctional aminopeptidase — —
Desulfovibrio vulgaris Miyazaki F 0.54 DvMF_3126 inosine-5'-monophosphate dehydrogenase (RefSeq) 0.28 DvMF_1538 Leucyl aminopeptidase (RefSeq) — —
Xanthobacter sp. DMC5 0.54 GFF3547 Inosine-5'-monophosphate dehydrogenase 0.28 GFF142 Cytosol aminopeptidase — —
Rhodospirillum rubrum S1H 0.54 Rru_A0244 IMP dehydrogenase (NCBI) 0.31 Rru_A0454 Leucyl aminopeptidase (NCBI) — —
Sinorhizobium meliloti 1021 0.53 SMc00815 inosine 5'-monophosphate dehydrogenase 0.28 SMc00585 leucyl aminopeptidase low > 103
Mycobacterium tuberculosis H37Rv 0.50 Rv3411c Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase) (imp oxidoreductase) (inosine-5'-monophosphate oxidoreductase) (IMPDH) (IMPD) 0.22 Rv2213 Probable aminopeptidase PepB — —

Not shown: 20 genomes with orthologs for CSW01_03980 only; 1 genomes with orthologs for CSW01_12680 only