Conservation of cofitness between BWI76_RS22660 and BWI76_RS09910 in Klebsiella michiganensis M5al

87 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS22660 5'/3'-nucleotidase SurE 1.0 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.35 4
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF4792 5-nucleotidase SurE (EC 3.1.3.5) @ Exopolyphosphatase (EC 3.6.1.11) 0.93 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) low > 78
Enterobacter sp. TBS_079 0.93 MPMX20_03630 5'/3'-nucleotidase SurE 0.92 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) low > 85
Enterobacter asburiae PDN3 0.93 EX28DRAFT_2840 3'-nucleotidase (EC 3.1.3.6)/5'-nucleotidase (EC 3.1.3.5)/exopolyphosphatase (EC 3.6.1.11) 0.92 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) — —
Escherichia coli BL21 0.92 ECD_02594 broad specificity 5'(3')-nucleotidase and polyphosphatase 0.93 ECD_00949 dihydro-orotate oxidase, FMN-linked low > 61
Escherichia coli BW25113 0.92 b2744 surE acid phosphatase (NCBI) 0.93 b0945 pyrD dihydroorotate dehydrogenase (NCBI) low > 76
Escherichia coli ECRC98 0.92 JDDGAC_24145 surE 5'/3'-nucleotidase SurE 0.93 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase low > 86
Escherichia coli ECRC102 0.92 NIAGMN_18250 surE 5'/3'-nucleotidase SurE 0.93 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC99 0.92 KEDOAH_07660 surE 5'/3'-nucleotidase SurE 0.93 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.92 OHPLBJKB_00989 '5'/3'-nucleotidase SurE' transl_table=11 0.93 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) low > 73
Escherichia fergusonii Becca 0.92 EFB2_01166 5'/3'-nucleotidase SurE 0.93 EFB2_03126 Dihydroorotate dehydrogenase (quinone) low > 86
Escherichia coli ECOR27 0.92 NOLOHH_12295 surE 5'/3'-nucleotidase SurE 0.93 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase low > 75
Escherichia coli ECRC62 0.92 BNILDI_10845 surE 5'/3'-nucleotidase SurE 0.93 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase low > 75
Escherichia coli ECRC101 0.92 MCAODC_11005 surE 5'/3'-nucleotidase SurE 0.93 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase low > 87
Escherichia coli ECRC100 0.92 OKFHMN_20480 surE 5'/3'-nucleotidase SurE 0.93 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase low > 80
Escherichia coli Nissle 1917 0.92 ECOLIN_RS15345 5'/3'-nucleotidase SurE 0.93 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECOR38 0.91 HEPCGN_19660 surE 5'/3'-nucleotidase SurE 0.93 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase low > 87
Erwinia tracheiphila SCR3 0.87 LU632_RS06465 surE 5'/3'-nucleotidase SurE 0.83 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase low > 74
Pantoea sp. MT58 0.87 IAI47_04220 5'/3'-nucleotidase SurE 0.82 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.46 63
Serratia liquefaciens MT49 0.82 IAI46_03775 5'/3'-nucleotidase SurE 0.86 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase low > 86
Rahnella sp. WP5 0.79 EX31_RS07840 5'/3'-nucleotidase SurE 0.87 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase low > 89
Shewanella sp. ANA-3 0.56 Shewana3_1121 surE stationary phase survival protein SurE (RefSeq) 0.65 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.71 13
Shewanella oneidensis MR-1 0.55 SO3435 surE stationary-phase survival protein SurE (NCBI ptt file) 0.64 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.55 Sama_1041 surE stationary phase survival protein SurE (RefSeq) 0.63 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) low > 62
Vibrio cholerae E7946 ATCC 55056 0.54 CSW01_02820 5'-nucleotidase SurE 0.71 CSW01_07490 dihydroorotate dehydrogenase (quinone) low > 62
Shewanella loihica PV-4 0.53 Shew_1210 stationary-phase survival protein SurE (RefSeq) 0.63 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) low > 60
Kangiella aquimarina DSM 16071 0.53 B158DRAFT_2296 3'-nucleotidase (EC 3.1.3.6)/5'-nucleotidase (EC 3.1.3.5)/exopolyphosphatase (EC 3.6.1.11) 0.56 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) — —
Rhodanobacter sp. FW510-T8 0.52 OKGIIK_08115 surE 5'/3'-nucleotidase SurE 0.47 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Dyella japonica UNC79MFTsu3.2 0.52 ABZR86_RS06595 5'/3'-nucleotidase SurE 0.49 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.52 LRK54_RS16650 5'/3'-nucleotidase SurE 0.49 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans MT42 0.52 LRK55_RS16375 5'/3'-nucleotidase SurE 0.49 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.51 Xcc-8004.3131.1 hypothetical protein 0.46 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Lysobacter sp. OAE881 0.50 ABIE51_RS06485 5'/3'-nucleotidase SurE 0.45 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase — —
Marinobacter adhaerens HP15 0.46 HP15_1279 stationary-phase survival protein SurE 0.48 HP15_1377 dihydroorotate dehydrogenase — —
Pseudomonas sp. S08-1 0.46 OH686_18170 5'/3'-nucleotidase SurE 0.56 OH686_03120 dihydroorotate dehydrogenase (fumarate) — —
Pseudomonas putida KT2440 0.46 PP_1620 5'(3')-nucleotidase and polyphosphatase 0.54 PP_2095 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas fluorescens FW300-N2E3 0.44 AO353_16600 stationary phase survival protein SurE 0.57 AO353_00780 dihydroorotate dehydrogenase (quinone) — —
Pseudomonas stutzeri RCH2 0.44 Psest_2810 5'/3'-nucleotidase SurE 0.55 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 low > 67
Pseudomonas fluorescens FW300-N1B4 0.44 Pf1N1B4_3112 5-nucleotidase SurE (EC 3.1.3.5) @ Exopolyphosphatase (EC 3.6.1.11) 0.58 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Castellaniella sp019104865 MT123 0.44 ABCV34_RS03030 5'/3'-nucleotidase SurE 0.52 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas syringae pv. syringae B728a 0.43 Psyr_1371 5'-nucleotidase / exopolyphosphatase / 3'-nucleotidase 0.57 Psyr_2106 dihydroorotate oxidase A — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.43 Psyr_1371 5'-nucleotidase / exopolyphosphatase / 3'-nucleotidase 0.57 Psyr_2106 dihydroorotate oxidase A — —
Dechlorosoma suillum PS 0.43 Dsui_1968 5''/3''-nucleotidase SurE 0.57 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 — —
Pseudomonas fluorescens SBW25-INTG 0.43 PFLU_RS06415 5'/3'-nucleotidase SurE 0.58 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas simiae WCS417 0.43 PS417_06350 stationary phase survival protein SurE 0.57 PS417_20935 dihydroorotate dehydrogenase — —
Pseudomonas fluorescens SBW25 0.43 PFLU_RS06415 5'/3'-nucleotidase SurE 0.58 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase — —
Variovorax sp. OAS795 0.43 ABID97_RS10715 5'/3'-nucleotidase SurE 0.50 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase — —
Variovorax sp. SCN45 0.43 GFF2845 5'-nucleotidase SurE (EC 3.1.3.5) 0.50 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) — —
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS22255 5'/3'-nucleotidase SurE 0.57 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.43 GFF3879 5-nucleotidase SurE (EC 3.1.3.5) 0.49 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) low > 90
Pseudomonas fluorescens GW456-L13 0.43 PfGW456L13_4678 5-nucleotidase SurE (EC 3.1.3.5) @ Exopolyphosphatase (EC 3.6.1.11) 0.56 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Paraburkholderia graminis OAS925 0.43 ABIE53_002054 5'-nucleotidase 0.57 ABIE53_001954 dihydroorotate dehydrogenase — —
Burkholderia phytofirmans PsJN 0.42 BPHYT_RS09100 stationary phase survival protein SurE 0.57 BPHYT_RS08565 dihydroorotate dehydrogenase low > 109
Paraburkholderia bryophila 376MFSha3.1 0.42 H281DRAFT_00840 5'-nucleotidase /3'-nucleotidase /exopolyphosphatase 0.55 H281DRAFT_00743 dihydroorotate oxidase A — —
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS13200 stationary phase survival protein SurE 0.53 RR42_RS07465 dihydroorotate dehydrogenase — —
Ralstonia solanacearum PSI07 0.42 RPSI07_RS18155 5'/3'-nucleotidase SurE 0.54 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase — —
Herbaspirillum seropedicae SmR1 0.42 HSERO_RS14845 stationary phase survival protein SurE 0.54 HSERO_RS16155 dihydroorotate dehydrogenase — —
Ralstonia sp. UNC404CL21Col 0.42 ABZR87_RS10860 5'/3'-nucleotidase SurE 0.55 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum GMI1000 0.42 RS_RS06030 5'-nucleotidase SurE 0.54 RS_RS08160 dihydroorotate dehydrogenase (quinone) — —
Ralstonia solanacearum IBSBF1503 0.41 RALBFv3_RS15220 5'/3'-nucleotidase SurE 0.55 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase — —
Ralstonia solanacearum UW163 0.41 UW163_RS12685 5'/3'-nucleotidase SurE 0.55 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase — —
Pseudomonas fluorescens FW300-N2E2 0.41 Pf6N2E2_3040 5-nucleotidase SurE (EC 3.1.3.5) 0.57 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Pseudomonas sp. RS175 0.41 PFR28_00424 '5'-nucleotidase SurE' transl_table=11 0.57 PFR28_01054 Dihydroorotate dehydrogenase (quinone) — —
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_05900 stationary phase survival protein SurE 0.57 AO356_02610 dihydroorotate dehydrogenase (quinone) — —
Acidovorax sp. GW101-3H11 0.40 Ac3H11_1784 5-nucleotidase SurE (EC 3.1.3.5) 0.52 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Acinetobacter radioresistens SK82 0.37 MPMX26_01054 5'-nucleotidase SurE 0.54 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) low > 36
Azospirillum brasilense Sp245 0.36 AZOBR_RS15460 5'-nucleotidase 0.38 AZOBR_RS13520 dihydroorotate dehydrogenase low > 97
Caulobacter crescentus NA1000 0.34 CCNA_02077 5'(3')-nucleotidase/polyphosphatase SurE 0.31 CCNA_00562 dihydroorotate dehydrogenase low > 66
Caulobacter crescentus NA1000 Δfur 0.34 CCNA_02077 5'(3')-nucleotidase/polyphosphatase SurE 0.31 CCNA_00562 dihydroorotate dehydrogenase low > 67
Magnetospirillum magneticum AMB-1 0.34 AMB_RS12675 5'-nucleotidase SurE 0.35 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.34 A4249_RS04645 5'/3'-nucleotidase SurE 0.37 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase — —
Azospirillum sp. SherDot2 0.33 MPMX19_01169 5'-nucleotidase SurE 0.38 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) — —
Rhodospirillum rubrum S1H 0.33 Rru_A1769 Acid phosphatase (NCBI) 0.37 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) — —
Bosea sp. OAE506 0.31 ABIE41_RS15015 5'/3'-nucleotidase SurE 0.33 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase low > 77
Rhodopseudomonas palustris CGA009 0.31 TX73_014710 5'/3'-nucleotidase SurE 0.38 TX73_004110 quinone-dependent dihydroorotate dehydrogenase — —
Sinorhizobium meliloti 1021 0.31 SMc02063 stationary phase survival protein SurE 0.40 SMc02245 dihydroorotate dehydrogenase 2 — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.30 ABZR88_RS03555 5'/3'-nucleotidase SurE 0.40 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase — —
Rhizobium sp. OAE497 0.30 ABIE40_RS08480 5'/3'-nucleotidase SurE 0.39 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase — —
Agrobacterium fabrum C58 0.30 Atu1702 stationary-phase survival protein 0.41 Atu0486 dihydroorotate dehydrogenase low > 89
Pedobacter sp. GW460-11-11-14-LB5 0.29 CA265_RS16310 5'/3'-nucleotidase SurE 0.42 CA265_RS14005 dihydroorotate dehydrogenase (quinone) — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.29 CA264_12185 5'/3'-nucleotidase SurE 0.40 CA264_00865 dihydroorotate dehydrogenase (quinone) low > 74
Sphingomonas koreensis DSMZ 15582 0.28 Ga0059261_0278 3'-nucleotidase (EC 3.1.3.6)/5'-nucleotidase (EC 3.1.3.5)/exopolyphosphatase (EC 3.6.1.11) 0.39 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.27 Echvi_3388 5'/3'-nucleotidase SurE 0.41 Echvi_1806 dihydroorotate dehydrogenase, subfamily 2 — —
Methanococcus maripaludis JJ 0.25 MMJJ_RS08930 5'/3'-nucleotidase SurE 0.11 MMJJ_RS02945 dihydroorotate dehydrogenase — —
Methanococcus maripaludis S2 0.25 MMP_RS05435 5'/3'-nucleotidase SurE 0.11 MMP_RS02330 dihydroorotate dehydrogenase — —
Phaeobacter inhibens DSM 17395 0.24 PGA1_c10770 5'-nucleotidase SurE 0.34 PGA1_c12150 dihydroorotate dehydrogenase PyrD low > 62
Bacteroides thetaiotaomicron VPI-5482 0.23 BT4003 stationary-phase survival protein SurE (NCBI ptt file) 0.26 BT1009 dihydroorotate dehydrogenase (NCBI ptt file) low > 81
Dinoroseobacter shibae DFL-12 0.23 Dshi_2136 stationary-phase survival protein SurE (RefSeq) 0.32 Dshi_0847 Dihydroorotate oxidase (RefSeq) low > 64

Not shown: 8 genomes with orthologs for BWI76_RS22660 only; 7 genomes with orthologs for BWI76_RS09910 only