Conservation of cofitness between BPHYT_RS33915 and BPHYT_RS06545 in Burkholderia phytofirmans PsJN

93 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Burkholderia phytofirmans PsJN 1.0 BPHYT_RS33915 isopropylmalate isomerase 1.0 BPHYT_RS06545 acetolactate synthase 0.94 4
Paraburkholderia bryophila 376MFSha3.1 0.97 H281DRAFT_06075 3-isopropylmalate dehydratase, large subunit 0.99 H281DRAFT_04551 acetolactate synthase, large subunit
Paraburkholderia graminis OAS925 0.96 ABIE53_004801 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit 0.99 ABIE53_001574 acetolactate synthase-1/2/3 large subunit
Paraburkholderia sabiae LMG 24235 0.95 QEN71_RS17605 3-isopropylmalate dehydratase large subunit 0.97 QEN71_RS24225 acetolactate synthase 3 catalytic subunit 0.86 9
Ralstonia solanacearum PSI07 0.87 RPSI07_RS14695 3-isopropylmalate dehydratase large subunit 0.82 RPSI07_RS14255 acetolactate synthase, large subunit, biosynthetic type
Ralstonia sp. UNC404CL21Col 0.87 ABZR87_RS14540 3-isopropylmalate dehydratase large subunit 0.81 ABZR87_RS14955 acetolactate synthase 3 catalytic subunit 0.59 49
Ralstonia solanacearum UW163 0.87 UW163_RS11105 3-isopropylmalate dehydratase large subunit 0.82 UW163_RS10675 acetolactate synthase 3 large subunit
Ralstonia solanacearum IBSBF1503 0.87 RALBFv3_RS02620 3-isopropylmalate dehydratase large subunit 0.82 RALBFv3_RS03050 acetolactate synthase 3 large subunit
Ralstonia solanacearum GMI1000 0.87 RS_RS10000 3-isopropylmalate dehydratase large subunit 0.81 RS_RS10420 acetolactate synthase 3 large subunit
Cupriavidus basilensis FW507-4G11 0.86 RR42_RS14400 isopropylmalate isomerase 0.80 RR42_RS05435 acetolactate synthase 3 catalytic subunit
Herbaspirillum seropedicae SmR1 0.80 HSERO_RS16515 isopropylmalate isomerase 0.74 HSERO_RS08650 acetolactate synthase 0.97 3
Castellaniella sp019104865 MT123 0.77 ABCV34_RS04290 3-isopropylmalate dehydratase large subunit 0.70 ABCV34_RS01210 acetolactate synthase 3 catalytic subunit 0.64 4
Variovorax sp. OAS795 0.75 ABID97_RS08465 3-isopropylmalate dehydratase large subunit 0.72 ABID97_RS14885 acetolactate synthase 3 catalytic subunit
Hydrogenophaga sp. GW460-11-11-14-LB1 0.75 GFF3363 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.74 GFF4276 Acetolactate synthase large subunit (EC 2.2.1.6)
Variovorax sp. SCN45 0.75 GFF3890 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.73 GFF1158 Acetolactate synthase large subunit (EC 2.2.1.6)
Acidovorax sp. GW101-3H11 0.74 Ac3H11_1525 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.72 Ac3H11_525 Acetolactate synthase large subunit (EC 2.2.1.6) 0.80 37
Marinobacter adhaerens HP15 0.73 HP15_1834 protein containing 3-isopropylmalate dehydratase, large subunit region domain 0.59 HP15_531 acetolactate synthase, large subunit, biosynthetic type 0.84 16
Pseudomonas sp. RS175 0.73 PFR28_02824 3-isopropylmalate dehydratase large subunit 0.57 PFR28_03699 Acetolactate synthase isozyme 3 large subunit 0.61 16
Pseudomonas fluorescens FW300-N2C3 0.73 AO356_21400 isopropylmalate isomerase 0.56 AO356_16170 acetolactate synthase 3 catalytic subunit 0.95 9
Pseudomonas fluorescens FW300-N2E3 0.72 AO353_20620 isopropylmalate isomerase 0.57 AO353_14495 acetolactate synthase 3 catalytic subunit 0.86 27
Xanthomonas campestris pv. campestris strain 8004 0.72 Xcc-8004.1049.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.35 Xcc-8004.1059.1 Acetolactate synthase large subunit (EC 2.2.1.6) 0.85 21
Pseudomonas fluorescens FW300-N2E2 0.72 Pf6N2E2_63 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.56 Pf6N2E2_5175 Acetolactate synthase large subunit (EC 2.2.1.6) 0.80 15
Pseudomonas stutzeri RCH2 0.72 Psest_2591 3-isopropylmalate dehydratase, large subunit 0.58 Psest_1036 acetolactate synthase, large subunit, biosynthetic type
Pseudomonas fluorescens GW456-L13 0.72 PfGW456L13_3948 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.56 PfGW456L13_1538 Acetolactate synthase large subunit (EC 2.2.1.6) 0.95 7
Pseudomonas syringae pv. syringae B728a ΔmexB 0.72 Psyr_1983 3-isopropylmalate dehydratase, large subunit 0.58 Psyr_0846 acetolactate synthase, large subunit 0.89 17
Pseudomonas syringae pv. syringae B728a 0.72 Psyr_1983 3-isopropylmalate dehydratase, large subunit 0.58 Psyr_0846 acetolactate synthase, large subunit 0.93 9
Pseudomonas fluorescens FW300-N1B4 0.72 Pf1N1B4_15 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.57 Pf1N1B4_2878 Acetolactate synthase large subunit (EC 2.2.1.6) 0.82 29
Pseudomonas simiae WCS417 0.72 PS417_18600 isopropylmalate isomerase 0.57 PS417_23810 acetolactate synthase 3 catalytic subunit 0.90 9
Pseudomonas putida KT2440 0.72 PP_1985 3-isopropylmalate dehydratase large subunit 0.57 PP_4680 acetohydroxybutanoate synthase / acetolactate synthase 0.92 2
Pseudomonas fluorescens SBW25-INTG 0.71 PFLU_RS20580 3-isopropylmalate dehydratase large subunit 0.57 PFLU_RS25650 acetolactate synthase 3 large subunit
Pseudomonas fluorescens SBW25 0.71 PFLU_RS20580 3-isopropylmalate dehydratase large subunit 0.57 PFLU_RS25650 acetolactate synthase 3 large subunit
Pseudomonas sp. S08-1 0.71 OH686_04480 3-isopropylmalate dehydratase large subunit 0.58 OH686_08130 acetolactate synthase, large subunit, biosynthetic type 0.91 4
Dechlorosoma suillum PS 0.70 Dsui_3201 3-isopropylmalate dehydratase, large subunit 0.68 Dsui_3529 acetolactate synthase, large subunit, biosynthetic type
Rhodospirillum rubrum S1H 0.69 Rru_A1189 3-isopropylmalate dehydratase large subunit region (NCBI) 0.53 Rru_A0467 Acetolactate synthase, large subunit, biosynthetic type (NCBI) 0.95 10
Acinetobacter radioresistens SK82 0.68 MPMX26_00345 3-isopropylmalate dehydratase large subunit 0.56 MPMX26_00472 Acetolactate synthase isozyme 3 large subunit 0.99 4
Azospirillum sp. SherDot2 0.68 MPMX19_01998 3-isopropylmalate dehydratase large subunit 0.54 MPMX19_01776 Acetolactate synthase isozyme 3 large subunit
Azospirillum brasilense Sp245 0.68 AZOBR_RS03545 isopropylmalate isomerase 0.55 AZOBR_RS06560 acetolactate synthase low > 97
Sinorhizobium meliloti 1021 0.66 SMc03823 isopropylmalate isomerase large subunit 0.53 SMc01431 acetolactate synthase 3 catalytic subunit 0.97 9
Bosea sp. OAE506 0.66 ABIE41_RS11660 3-isopropylmalate dehydratase large subunit 0.52 ABIE41_RS12890 acetolactate synthase 3 large subunit
Rhizobium sp. OAE497 0.65 ABIE40_RS18380 3-isopropylmalate dehydratase large subunit 0.54 ABIE40_RS11495 acetolactate synthase 3 large subunit 0.90 48
Agrobacterium fabrum C58 0.65 Atu2709 3-isopropylmalate dehydratase, large subunit 0.52 Atu2036 acetolactate synthase III, large subunit 0.88 34
Rhodopseudomonas palustris CGA009 0.64 TX73_001245 3-isopropylmalate dehydratase large subunit 0.52 TX73_010465 acetolactate synthase 3 large subunit
Magnetospirillum magneticum AMB-1 0.64 AMB_RS20560 3-isopropylmalate dehydratase large subunit 0.54 AMB_RS17740 acetolactate synthase 3 large subunit
Pantoea sp. MT58 0.62 IAI47_16010 3-isopropylmalate dehydratase large subunit 0.55 IAI47_15990 acetolactate synthase 3 large subunit low > 76
Enterobacter asburiae PDN3 0.62 EX28DRAFT_3668 3-isopropylmalate dehydratase, large subunit 0.55 EX28DRAFT_3673 acetolactate synthase, large subunit (EC 2.2.1.6) low > 76
Escherichia fergusonii Becca 0.62 EFB2_03973 3-isopropylmalate dehydratase large subunit 0.55 EFB2_03969 Acetolactate synthase isozyme 3 large subunit low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.62 GFF166 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) 0.54 GFF161 Acetolactate synthase large subunit (EC 2.2.1.6) low > 78
Escherichia coli Nissle 1917 0.62 ECOLIN_RS00390 3-isopropylmalate dehydratase large subunit 0.55 ECOLIN_RS00415 acetolactate synthase 3 large subunit low > 55
Escherichia coli ECRC62 0.62 BNILDI_08540 leuC1 3-isopropylmalate dehydratase large subunit 1 0.55 BNILDI_08565 ilvI acetolactate synthase 3 large subunit low > 75
Escherichia coli ECOR38 0.62 HEPCGN_08705 leuC1 3-isopropylmalate dehydratase large subunit 1 0.55 HEPCGN_08680 ilvI acetolactate synthase 3 large subunit low > 87
Escherichia coli ECOR27 0.62 NOLOHH_03070 leuC1 3-isopropylmalate dehydratase large subunit 1 0.55 NOLOHH_03045 ilvI acetolactate synthase 3 large subunit low > 75
Escherichia coli BL21 0.62 ECD_00074 3-isopropylmalate dehydratase large subunit 0.55 ECD_00079 acetolactate synthase 3 large subunit low > 61
Escherichia coli BW25113 0.62 b0072 leuC isopropylmalate isomerase large subunit (NCBI) 0.55 b0077 ilvI acetolactate synthase III large subunit (NCBI) low > 76
Caulobacter crescentus NA1000 Δfur 0.62 CCNA_00196 3-isopropylmalate dehydratase large subunit 0.55 CCNA_02185 acetolactate synthase large subunit low > 67
Caulobacter crescentus NA1000 0.62 CCNA_00196 3-isopropylmalate dehydratase large subunit 0.55 CCNA_02185 acetolactate synthase large subunit 0.92 31
Rahnella sp. WP5 0.62 EX31_RS03690 3-isopropylmalate dehydratase large subunit 0.55 EX31_RS03665 acetolactate synthase 3 large subunit low > 89
Escherichia coli HS(pFamp)R (ATCC 700891) 0.62 OHPLBJKB_03585 3-isopropylmalate dehydratase large subunit 0.55 OHPLBJKB_03581 Acetolactate synthase isozyme 3 large subunit low > 73
Dickeya dianthicola ME23 0.62 DZA65_RS19210 3-isopropylmalate dehydratase large subunit 0.56 DZA65_RS19185 acetolactate synthase 3 large subunit low > 75
Dickeya dianthicola 67-19 0.62 HGI48_RS18065 3-isopropylmalate dehydratase large subunit 0.56 HGI48_RS18040 acetolactate synthase 3 large subunit low > 71
Escherichia coli ECRC101 0.61 MCAODC_01240 leuC1 3-isopropylmalate dehydratase large subunit 1 0.55 MCAODC_01215 ilvI acetolactate synthase 3 large subunit low > 87
Escherichia coli ECRC100 0.61 OKFHMN_10725 leuC1 3-isopropylmalate dehydratase large subunit 1 0.55 OKFHMN_10700 ilvI acetolactate synthase 3 large subunit low > 80
Escherichia coli ECRC99 0.61 KEDOAH_17430 leuC1 3-isopropylmalate dehydratase large subunit 1 0.55 KEDOAH_17455 ilvI acetolactate synthase 3 large subunit
Escherichia coli ECRC98 0.61 JDDGAC_14320 leuC1 3-isopropylmalate dehydratase large subunit 1 0.55 JDDGAC_14295 ilvI acetolactate synthase 3 large subunit low > 86
Escherichia coli ECRC102 0.61 NIAGMN_08575 leuC1 3-isopropylmalate dehydratase large subunit 1 0.55 NIAGMN_08550 ilvI acetolactate synthase 3 large subunit
Enterobacter sp. TBS_079 0.61 MPMX20_00767 3-isopropylmalate dehydratase large subunit 1 0.55 MPMX20_00771 Acetolactate synthase isozyme 3 large subunit low > 85
Klebsiella michiganensis M5al 0.61 BWI76_RS04670 3-isopropylmalate dehydratase large subunit 0.55 BWI76_RS04695 acetolactate synthase 3 large subunit low > 92
Dickeya dadantii 3937 0.61 DDA3937_RS18125 3-isopropylmalate dehydratase large subunit 0.56 DDA3937_RS18105 acetolactate synthase 3 large subunit low > 74
Pectobacterium carotovorum WPP14 0.61 HER17_RS03075 3-isopropylmalate dehydratase large subunit 0.56 HER17_RS03095 acetolactate synthase 3 large subunit low > 75
Vibrio cholerae E7946 ATCC 55056 0.59 CSW01_12605 3-isopropylmalate dehydratase large subunit 0.56 CSW01_12565 acetolactate synthase 3 large subunit low > 62
Phaeobacter inhibens DSM 17395 0.59 PGA1_c29780 3-isopropylmalate dehydratase large subunit 0.49 PGA1_c20210 acetolactate synthase isozyme 3 large subunit 0.90 8
Serratia liquefaciens MT49 0.59 IAI46_03345 3-isopropylmalate dehydratase large subunit 0.56 IAI46_03375 acetolactate synthase 3 large subunit low > 86
Shewanella loihica PV-4 0.59 Shew_3470 isopropylmalate isomerase large subunit (RefSeq) 0.56 Shew_1776 acetolactate synthase 3 catalytic subunit (RefSeq) low > 60
Shewanella oneidensis MR-1 0.59 SO4234 leuC 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) 0.57 SO2279 ilvI acetolactate synthase III, large subunit (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.59 Shewana3_3759 isopropylmalate isomerase large subunit (RefSeq) 0.57 Shewana3_2269 acetolactate synthase 3 catalytic subunit (RefSeq) low > 73
Erwinia tracheiphila SCR3 0.58 LU632_RS02870 leuC 3-isopropylmalate dehydratase large subunit 0.57 LU632_RS02885 ilvI acetolactate synthase 3 large subunit low > 74
Shewanella amazonensis SB2B 0.58 Sama_0337 isopropylmalate isomerase large subunit (RefSeq) 0.56 Sama_2018 acetolactate synthase 3 catalytic subunit (RefSeq) low > 62
Dinoroseobacter shibae DFL-12 0.58 Dshi_0085 3-isopropylmalate dehydratase, large subunit (RefSeq) 0.50 Dshi_1779 acetolactate synthase, large subunit, biosynthetic type (RefSeq)
Sphingomonas koreensis DSMZ 15582 0.58 Ga0059261_4223 3-isopropylmalate dehydratase, large subunit 0.48 Ga0059261_0068 acetolactate synthase, large subunit (EC 2.2.1.6) 0.99 7
Mycobacterium tuberculosis H37Rv 0.57 Rv2988c Probable 3-isopropylmalate dehydratase (large subunit) LeuC (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) 0.44 Rv3003c Acetolactate synthase (large subunit) IlvB1 (acetohydroxy-acid synthase)
Alteromonas macleodii MIT1002 0.57 MIT1002_00947 3-isopropylmalate dehydratase large subunit 0.54 MIT1002_00503 Acetolactate synthase isozyme 3 large subunit 0.99 6
Bifidobacterium breve UCC2003 0.54 BBR_RS19630 3-isopropylmalate dehydratase large subunit 0.39 BBR_RS12350 acetolactate synthase large subunit low > 34
Mucilaginibacter yixingensis YX-36 DSM 26809 0.52 ABZR88_RS11595 3-isopropylmalate dehydratase large subunit 0.37 ABZR88_RS11580 biosynthetic-type acetolactate synthase large subunit
Pontibacter actiniarum KMM 6156, DSM 19842 0.51 CA264_09435 3-isopropylmalate dehydratase large subunit 0.36 CA264_06930 acetolactate synthase, large subunit, biosynthetic type low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.51 CA265_RS15830 3-isopropylmalate dehydratase large subunit 0.36 CA265_RS15805 acetolactate synthase, large subunit, biosynthetic type 0.94 13
Bacteroides thetaiotaomicron VPI-5482 0.50 BT1860 3-isopropylmalate dehydratase large subunit (NCBI ptt file) 0.37 BT2077 acetolactate synthase large subunit (NCBI ptt file) 0.91 5
Bacteroides stercoris CC31F 0.50 HMPREF1181_RS14145 3-isopropylmalate dehydratase large subunit 0.37 HMPREF1181_RS08330 biosynthetic-type acetolactate synthase large subunit 0.94 8
Phocaeicola dorei CL03T12C01 0.50 ABI39_RS10200 3-isopropylmalate dehydratase large subunit 0.36 ABI39_RS12720 biosynthetic-type acetolactate synthase large subunit 0.94 1
Bacteroides ovatus ATCC 8483 0.50 BACOVA_04603 3-isopropylmalate dehydratase, large subunit 0.36 BACOVA_03303 acetolactate synthase, large subunit, biosynthetic type 0.98 3
Phocaeicola vulgatus CL09T03C04 0.49 HMPREF1058_RS14550 3-isopropylmalate dehydratase large subunit 0.36 HMPREF1058_RS16820 biosynthetic-type acetolactate synthase large subunit low > 67
Echinicola vietnamensis KMM 6221, DSM 17526 0.49 Echvi_2059 3-isopropylmalate dehydratase, large subunit 0.38 Echvi_2056 acetolactate synthase, large subunit, biosynthetic type 0.75 8
Parabacteroides merdae CL09T00C40 0.49 HMPREF1078_RS16660 3-isopropylmalate dehydratase large subunit 0.37 HMPREF1078_RS16690 biosynthetic-type acetolactate synthase large subunit 0.92 53
Lysobacter sp. OAE881 0.48 ABIE51_RS17575 3-isopropylmalate dehydratase large subunit 0.39 ABIE51_RS17550 acetolactate synthase 2 catalytic subunit 0.95 8
Synechococcus elongatus PCC 7942 0.47 Synpcc7942_1898 leuC isopropylmalate isomerase large subunit 0.47 Synpcc7942_0139 ilvB acetolactate synthase 3 catalytic subunit
Brevundimonas sp. GW460-12-10-14-LB2 0.46 A4249_RS10005 3-isopropylmalate dehydratase large subunit 0.36 A4249_RS10020 acetolactate synthase 2 catalytic subunit 0.99 17

Not shown: 5 genomes with orthologs for BPHYT_RS33915 only; 4 genomes with orthologs for BPHYT_RS06545 only