Conservation of cofitness between BBR_RS15810 and BBR_RS16095 in Bifidobacterium breve UCC2003

91 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bifidobacterium breve UCC2003 1.0 BBR_RS15810 tryptophan synthase subunit alpha 1.0 BBR_RS16095 imidazole glycerol phosphate synthase subunit HisF 0.29 10
Mycobacterium tuberculosis H37Rv 0.40 Rv1613 Probable tryptophan synthase, alpha subunit TrpA 0.62 Rv1605 Probable cyclase HisF
Rhizobium sp. OAE497 0.27 ABIE40_RS19340 tryptophan synthase subunit alpha 0.54 ABIE40_RS19440 imidazole glycerol phosphate synthase subunit HisF
Methanococcus maripaludis S2 0.27 MMP_RS05185 tryptophan synthase subunit alpha 0.51 MMP_RS08865 imidazole glycerol phosphate synthase subunit HisF
Pseudomonas stutzeri RCH2 0.27 Psest_0062 tryptophan synthase, alpha subunit 0.55 Psest_0156 imidazoleglycerol phosphate synthase, cyclase subunit
Methanococcus maripaludis JJ 0.26 MMJJ_RS09195 tryptophan synthase subunit alpha 0.51 MMJJ_RS05490 imidazole glycerol phosphate synthase subunit HisF
Pseudomonas sp. S08-1 0.26 OH686_12430 tryptophan synthase, alpha subunit 0.55 OH686_14595 Imidazole glycerol phosphate synthase cyclase subunit 0.74 35
Synechococcus elongatus PCC 7942 0.26 Synpcc7942_0411 trpA tryptophan synthase subunit alpha 0.51 Synpcc7942_2087 hisF imidazole glycerol phosphate synthase subunit HisF
Marinobacter adhaerens HP15 0.26 HP15_1826 tryptophan synthase, alpha subunit 0.54 HP15_3009 protein containing histidine biosynthesis, HisF domain
Phaeobacter inhibens DSM 17395 0.26 PGA1_c04930 tryptophan synthase alpha chain 0.47 PGA1_c09240 imidazole glycerol phosphate synthase subunit HisF
Agrobacterium fabrum C58 0.26 Atu0019 tryptophan synthase alpha subunit 0.51 Atu0039 imidazoleglycerol-phosphate synthase cyclase
Magnetospirillum magneticum AMB-1 0.26 AMB_RS20300 tryptophan synthase subunit alpha 0.52 AMB_RS22925 imidazole glycerol phosphate synthase cyclase subunit
Rhodopseudomonas palustris CGA009 0.26 TX73_000365 tryptophan synthase subunit alpha 0.47 TX73_001625 imidazole glycerol phosphate synthase subunit HisF
Pseudomonas fluorescens SBW25-INTG 0.25 PFLU_RS00175 tryptophan synthase subunit alpha 0.54 PFLU_RS01625 imidazole glycerol phosphate synthase subunit HisF 0.70 21
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_10705 tryptophan synthase subunit alpha 0.53 AO353_12090 imidazole glycerol phosphate synthase subunit HisF 0.78 26
Pseudomonas simiae WCS417 0.25 PS417_00180 tryptophan synthase subunit alpha 0.53 PS417_01580 imidazole glycerol phosphate synthase 0.65 24
Pseudomonas fluorescens SBW25 0.25 PFLU_RS00175 tryptophan synthase subunit alpha 0.54 PFLU_RS01625 imidazole glycerol phosphate synthase subunit HisF low > 109
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_565 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.54 PfGW456L13_358 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.77 41
Pseudomonas sp. RS175 0.25 PFR28_04716 Tryptophan synthase alpha chain 0.54 PFR28_04933 Imidazole glycerol phosphate synthase subunit HisF
Dinoroseobacter shibae DFL-12 0.25 Dshi_0952 tryptophan synthase, alpha subunit (RefSeq) 0.50 Dshi_2576 imidazoleglycerol phosphate synthase, cyclase subunit (RefSeq)
Pseudomonas fluorescens FW300-N2C3 0.25 AO356_10910 tryptophan synthase subunit alpha 0.54 AO356_09795 imidazole glycerol phosphate synthase subunit HisF 0.70 47
Sinorhizobium meliloti 1021 0.25 SMc02765 tryptophan synthase subunit alpha 0.50 SMc02569 imidazole glycerol phosphate synthase subunit HisF 0.71 47
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_1830 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.54 Pf1N1B4_1623 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Mucilaginibacter yixingensis YX-36 DSM 26809 0.25 ABZR88_RS10660 tryptophan synthase subunit alpha 0.46 ABZR88_RS06855 imidazole glycerol phosphate synthase subunit HisF
Pseudomonas fluorescens FW300-N2E2 0.25 Pf6N2E2_4047 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.54 Pf6N2E2_3838 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Acinetobacter radioresistens SK82 0.25 MPMX26_02611 Tryptophan synthase alpha chain 0.50 MPMX26_02854 Imidazole glycerol phosphate synthase subunit HisF
Pseudomonas syringae pv. syringae B728a ΔmexB 0.24 Psyr_0033 tryptophan synthase, alpha chain 0.55 Psyr_4893 imidazole glycerol phosphate synthase subunit hisF
Pseudomonas syringae pv. syringae B728a 0.24 Psyr_0033 tryptophan synthase, alpha chain 0.55 Psyr_4893 imidazole glycerol phosphate synthase subunit hisF 0.59 26
Kangiella aquimarina DSM 16071 0.24 B158DRAFT_2430 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.45 B158DRAFT_2291 imidazoleglycerol phosphate synthase, cyclase subunit low > 40
Pseudomonas putida KT2440 0.24 PP_0082 tryptophan synthase alpha chain 0.55 PP_0293 Imidazole glycerol phosphate synthase subunit HisF 0.81 23
Acidovorax sp. GW101-3H11 0.24 Ac3H11_1535 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.48 Ac3H11_4733 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-)
Parabacteroides merdae CL09T00C40 0.23 HMPREF1078_RS00120 tryptophan synthase subunit alpha 0.45 HMPREF1078_RS13565 imidazole glycerol phosphate synthase subunit HisF 0.97 17
Variovorax sp. SCN45 0.23 GFF3882 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.53 GFF5357 Imidazole glycerol phosphate synthase cyclase subunit
Dechlorosoma suillum PS 0.23 Dsui_3191 tryptophan synthase, alpha subunit 0.51 Dsui_1418 imidazoleglycerol phosphate synthase, cyclase subunit
Phocaeicola vulgatus CL09T03C04 0.23 HMPREF1058_RS07200 tryptophan synthase subunit alpha 0.44 HMPREF1058_RS06175 imidazole glycerol phosphate synthase subunit HisF 0.90 20
Phocaeicola dorei CL03T12C01 0.23 ABI39_RS21075 tryptophan synthase subunit alpha 0.44 ABI39_RS19930 imidazole glycerol phosphate synthase subunit HisF 0.77 22
Bosea sp. OAE506 0.23 ABIE41_RS03930 tryptophan synthase subunit alpha 0.46 ABIE41_RS03810 imidazole glycerol phosphate synthase subunit HisF
Bacteroides stercoris CC31F 0.23 HMPREF1181_RS15350 tryptophan synthase subunit alpha 0.44 HMPREF1181_RS11070 imidazole glycerol phosphate synthase subunit HisF 0.83 34
Shewanella oneidensis MR-1 0.23 SO3024 trpA tryptophan synthase, alpha subunit (NCBI ptt file) 0.39 SO2068 hisF hisF protein (cyclase) (NCBI ptt file) 0.92 22
Serratia liquefaciens MT49 0.22 IAI46_14045 tryptophan synthase subunit alpha 0.42 IAI46_08185 imidazole glycerol phosphate synthase subunit HisF low > 86
Shewanella sp. ANA-3 0.22 Shewana3_1515 trpA tryptophan synthase subunit alpha (RefSeq) 0.39 Shewana3_1848 imidazole glycerol phosphate synthase subunit HisF (RefSeq) 0.91 35
Bacteroides thetaiotaomicron VPI-5482 0.22 BT0527 tryptophan synthase alpha chain (NCBI ptt file) 0.46 BT1378 imidazole glycerol phosphate synthase subunit hisF (NCBI ptt file) 0.73 41
Cupriavidus basilensis FW507-4G11 0.22 RR42_RS14350 tryptophan synthase alpha chain 0.53 RR42_RS18885 imidazole glycerol phosphate synthase
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS14490 tryptophan synthase subunit alpha 0.51 ABZR87_RS02470 imidazole glycerol phosphate synthase subunit HisF
Bacteroides ovatus ATCC 8483 0.22 BACOVA_03785 tryptophan synthase, alpha subunit 0.46 BACOVA_00219 imidazoleglycerol phosphate synthase, cyclase subunit 0.96 11
Azospirillum brasilense Sp245 0.22 AZOBR_RS00520 tryptophan synthase subunit alpha 0.53 AZOBR_RS01685 imidazole glycerol phosphate synthase 0.84 13
Variovorax sp. OAS795 0.22 ABID97_RS08425 tryptophan synthase subunit alpha 0.52 ABID97_RS23105 imidazole glycerol phosphate synthase subunit HisF
Vibrio cholerae E7946 ATCC 55056 0.22 CSW01_05925 tryptophan synthase subunit alpha 0.40 CSW01_05775 imidazole glycerol phosphate synthase cyclase subunit low > 62
Caulobacter crescentus NA1000 0.22 CCNA_03657 tryptophan synthase alpha chain 0.49 CCNA_03853 imidazole glycerol phosphate synthase, cyclase subunit 0.87 36
Caulobacter crescentus NA1000 Δfur 0.22 CCNA_03657 tryptophan synthase alpha chain 0.49 CCNA_03853 imidazole glycerol phosphate synthase, cyclase subunit low > 67
Ralstonia solanacearum PSI07 0.21 RPSI07_RS14740 tryptophan synthase subunit alpha 0.51 RPSI07_RS10420 imidazole glycerol phosphate synthase subunit HisF
Azospirillum sp. SherDot2 0.21 MPMX19_02737 Tryptophan synthase alpha chain 0.53 MPMX19_02542 Imidazole glycerol phosphate synthase subunit HisF
Pantoea sp. MT58 0.21 IAI47_09165 tryptophan synthase subunit alpha 0.42 IAI47_07065 imidazole glycerol phosphate synthase subunit HisF 0.95 9
Brevundimonas sp. GW460-12-10-14-LB2 0.21 A4249_RS11320 tryptophan synthase subunit alpha 0.38 A4249_RS10715 imidazole glycerol phosphate synthase subunit HisF
Ralstonia solanacearum GMI1000 0.21 RS_RS09955 tryptophan synthase subunit alpha 0.50 RS_RS14760 imidazole glycerol phosphate synthase subunit HisF
Ralstonia solanacearum IBSBF1503 0.21 RALBFv3_RS02575 tryptophan synthase subunit alpha 0.51 RALBFv3_RS06815 imidazole glycerol phosphate synthase subunit HisF
Ralstonia solanacearum UW163 0.21 UW163_RS11150 tryptophan synthase subunit alpha 0.51 UW163_RS06800 imidazole glycerol phosphate synthase subunit HisF
Klebsiella michiganensis M5al 0.21 BWI76_RS11840 tryptophan synthase subunit alpha 0.40 BWI76_RS18950 imidazole glycerol phosphate synthase cyclase subunit 0.86 37
Alteromonas macleodii MIT1002 0.21 MIT1002_01425 Tryptophan synthase alpha chain 0.41 MIT1002_02638 Imidazole glycerol phosphate synthase subunit HisF
Herbaspirillum seropedicae SmR1 0.21 HSERO_RS16470 tryptophan synthase subunit alpha 0.55 HSERO_RS20315 imidazole glycerol phosphate synthase 0.48 42
Desulfovibrio vulgaris Miyazaki F 0.21 DvMF_1740 trpA tryptophan synthase subunit alpha (RefSeq) 0.48 DvMF_2304 imidazole glycerol phosphate synthase subunit HisF (RefSeq) 0.83 22
Paraburkholderia graminis OAS925 0.21 ABIE53_004811 tryptophan synthase alpha chain 0.53 ABIE53_003695 cyclase
Dickeya dianthicola ME23 0.20 DZA65_RS10940 tryptophan synthase subunit alpha 0.41 DZA65_RS10030 imidazole glycerol phosphate synthase subunit HisF low > 75
Dickeya dianthicola 67-19 0.20 HGI48_RS10460 tryptophan synthase subunit alpha 0.41 HGI48_RS09720 imidazole glycerol phosphate synthase subunit HisF
Dickeya dadantii 3937 0.20 DDA3937_RS10460 tryptophan synthase subunit alpha 0.41 DDA3937_RS09710 imidazole glycerol phosphate synthase subunit HisF 0.59 55
Rahnella sp. WP5 0.20 EX31_RS09980 tryptophan synthase subunit alpha 0.41 EX31_RS11465 imidazole glycerol phosphate synthase subunit HisF 0.97 16
Enterobacter asburiae PDN3 0.20 EX28DRAFT_0932 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.39 EX28DRAFT_0534 imidazoleglycerol phosphate synthase, cyclase subunit low > 76
Shewanella loihica PV-4 0.20 Shew_2256 trpA tryptophan synthase subunit alpha (RefSeq) 0.39 Shew_2203 imidazole glycerol phosphate synthase subunit HisF (RefSeq) 0.92 33
Xanthomonas campestris pv. campestris strain 8004 0.20 Xcc-8004.1967.1 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.38 Xcc-8004.2943.1 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) 0.89 10
Escherichia fergusonii Becca 0.20 EFB2_02666 Tryptophan synthase alpha chain 0.41 EFB2_01831 Imidazole glycerol phosphate synthase subunit HisF low > 86
Enterobacter sp. TBS_079 0.20 MPMX20_02514 Tryptophan synthase alpha chain 0.40 MPMX20_03007 Imidazole glycerol phosphate synthase subunit HisF 0.89 25
Escherichia coli ECOR38 0.19 HEPCGN_25515 trpA tryptophan synthase subunit alpha 0.41 HEPCGN_03195 hisF Imidazole glycerol phosphate synthase subunit HisF 0.84 78
Escherichia coli HS(pFamp)R (ATCC 700891) 0.19 OHPLBJKB_02423 Tryptophan synthase alpha chain 0.40 OHPLBJKB_01675 Imidazole glycerol phosphate synthase subunit HisF low > 73
Escherichia coli BL21 0.19 ECD_01234 tryptophan synthase, alpha subunit 0.41 ECD_01927 imidazole glycerol phosphate synthase, catalytic subunit with HisH
Escherichia coli Nissle 1917 0.19 ECOLIN_RS07595 tryptophan synthase subunit alpha 0.41 ECOLIN_RS11970 imidazole glycerol phosphate synthase subunit HisF
Escherichia coli BW25113 0.19 b1260 trpA tryptophan synthase subunit alpha (NCBI) 0.41 b2025 hisF imidazole glycerol phosphate synthase subunit HisF (NCBI) 0.92 11
Erwinia tracheiphila SCR3 0.19 LU632_RS12775 trpA tryptophan synthase subunit alpha 0.40 LU632_RS08920 hisF imidazole glycerol phosphate synthase subunit HisF 0.49 34
Pectobacterium carotovorum WPP14 0.19 HER17_RS10940 tryptophan synthase subunit alpha 0.40 HER17_RS12255 imidazole glycerol phosphate synthase subunit HisF 0.98 4
Escherichia coli ECRC62 0.19 BNILDI_18480 trpA tryptophan synthase subunit alpha 0.41 BNILDI_14715 hisF Imidazole glycerol phosphate synthase subunit HisF 0.88 65
Escherichia coli ECOR27 0.19 NOLOHH_20335 trpA tryptophan synthase subunit alpha 0.41 NOLOHH_15805 hisF Imidazole glycerol phosphate synthase subunit HisF 0.86 43
Escherichia coli ECRC100 0.19 OKFHMN_02675 trpA tryptophan synthase subunit alpha 0.41 OKFHMN_24490 hisF Imidazole glycerol phosphate synthase subunit HisF
Escherichia coli ECRC99 0.19 KEDOAH_26075 trpA tryptophan synthase subunit alpha 0.41 KEDOAH_03660 hisF Imidazole glycerol phosphate synthase subunit HisF
Escherichia coli ECRC98 0.19 JDDGAC_05220 trpA tryptophan synthase subunit alpha 0.41 JDDGAC_28600 hisF Imidazole glycerol phosphate synthase subunit HisF 0.70 78
Escherichia coli ECRC102 0.19 NIAGMN_26845 trpA tryptophan synthase subunit alpha 0.41 NIAGMN_22435 hisF Imidazole glycerol phosphate synthase subunit HisF
Escherichia coli ECRC101 0.19 MCAODC_15590 trpA tryptophan synthase subunit alpha 0.41 MCAODC_20450 hisF Imidazole glycerol phosphate synthase subunit HisF 0.76 61
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.19 GFF2726 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.39 GFF3907 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) low > 78
Paraburkholderia bryophila 376MFSha3.1 0.19 H281DRAFT_06065 tryptophan synthase, alpha chain 0.53 H281DRAFT_05659 imidazole glycerol phosphate synthase subunit hisF
Castellaniella sp019104865 MT123 0.19 ABCV34_RS08430 tryptophan synthase subunit alpha 0.52 ABCV34_RS11250 imidazole glycerol phosphate synthase subunit HisF
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS33865 tryptophan synthase alpha chain 0.53 BPHYT_RS17680 imidazole glycerol phosphate synthase subunit HisF 0.83 34
Shewanella amazonensis SB2B 0.18 Sama_2134 trpA tryptophan synthase subunit alpha (RefSeq) 0.39 Sama_1947 imidazole glycerol phosphate synthase subunit HisF (RefSeq) 0.89 40
Paraburkholderia sabiae LMG 24235 0.18 QEN71_RS17655 tryptophan synthase subunit alpha 0.54 QEN71_RS27835 imidazole glycerol phosphate synthase subunit HisF 0.84 34
Sphingomonas koreensis DSMZ 15582 0.18 Ga0059261_0239 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.49 Ga0059261_1048 imidazoleglycerol phosphate synthase, cyclase subunit 0.87 35

Not shown: 0 genomes with orthologs for BBR_RS15810 only; 10 genomes with orthologs for BBR_RS16095 only