Conservation of cofitness between BBR_RS15810 and BBR_RS12350 in Bifidobacterium breve UCC2003

90 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bifidobacterium breve UCC2003 1.0 BBR_RS15810 tryptophan synthase subunit alpha 1.0 BBR_RS12350 acetolactate synthase large subunit 0.28 14
Mycobacterium tuberculosis H37Rv 0.40 Rv1613 Probable tryptophan synthase, alpha subunit TrpA 0.52 Rv3003c Acetolactate synthase (large subunit) IlvB1 (acetohydroxy-acid synthase)
Rhizobium sp. OAE497 0.27 ABIE40_RS19340 tryptophan synthase subunit alpha 0.36 ABIE40_RS11495 acetolactate synthase 3 large subunit
Methanococcus maripaludis S2 0.27 MMP_RS05185 tryptophan synthase subunit alpha 0.31 MMP_RS03415 acetolactate synthase large subunit
Pseudomonas stutzeri RCH2 0.27 Psest_0062 tryptophan synthase, alpha subunit 0.35 Psest_1036 acetolactate synthase, large subunit, biosynthetic type
Methanococcus maripaludis JJ 0.26 MMJJ_RS09195 tryptophan synthase subunit alpha 0.31 MMJJ_RS01650 acetolactate synthase large subunit
Synechococcus elongatus PCC 7942 0.26 Synpcc7942_0411 trpA tryptophan synthase subunit alpha 0.39 Synpcc7942_0139 ilvB acetolactate synthase 3 catalytic subunit
Pseudomonas sp. S08-1 0.26 OH686_12430 tryptophan synthase, alpha subunit 0.34 OH686_08130 acetolactate synthase, large subunit, biosynthetic type 0.80 22
Marinobacter adhaerens HP15 0.26 HP15_1826 tryptophan synthase, alpha subunit 0.35 HP15_531 acetolactate synthase, large subunit, biosynthetic type
Phaeobacter inhibens DSM 17395 0.26 PGA1_c04930 tryptophan synthase alpha chain 0.33 PGA1_c20210 acetolactate synthase isozyme 3 large subunit
Agrobacterium fabrum C58 0.26 Atu0019 tryptophan synthase alpha subunit 0.36 Atu2036 acetolactate synthase III, large subunit
Rhodopseudomonas palustris CGA009 0.26 TX73_000365 tryptophan synthase subunit alpha 0.36 TX73_010465 acetolactate synthase 3 large subunit
Magnetospirillum magneticum AMB-1 0.26 AMB_RS20300 tryptophan synthase subunit alpha 0.37 AMB_RS17740 acetolactate synthase 3 large subunit
Pseudomonas fluorescens SBW25-INTG 0.25 PFLU_RS00175 tryptophan synthase subunit alpha 0.35 PFLU_RS25650 acetolactate synthase 3 large subunit
Pseudomonas simiae WCS417 0.25 PS417_00180 tryptophan synthase subunit alpha 0.35 PS417_23810 acetolactate synthase 3 catalytic subunit 0.68 12
Pseudomonas fluorescens FW300-N2E3 0.25 AO353_10705 tryptophan synthase subunit alpha 0.35 AO353_14495 acetolactate synthase 3 catalytic subunit 0.83 8
Pseudomonas fluorescens SBW25 0.25 PFLU_RS00175 tryptophan synthase subunit alpha 0.35 PFLU_RS25650 acetolactate synthase 3 large subunit
Pseudomonas fluorescens GW456-L13 0.25 PfGW456L13_565 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.35 PfGW456L13_1538 Acetolactate synthase large subunit (EC 2.2.1.6) 0.87 8
Pseudomonas sp. RS175 0.25 PFR28_04716 Tryptophan synthase alpha chain 0.35 PFR28_03699 Acetolactate synthase isozyme 3 large subunit
Dinoroseobacter shibae DFL-12 0.25 Dshi_0952 tryptophan synthase, alpha subunit (RefSeq) 0.33 Dshi_1779 acetolactate synthase, large subunit, biosynthetic type (RefSeq)
Pseudomonas fluorescens FW300-N2C3 0.25 AO356_10910 tryptophan synthase subunit alpha 0.35 AO356_16170 acetolactate synthase 3 catalytic subunit 0.95 8
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_1830 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.35 Pf1N1B4_2878 Acetolactate synthase large subunit (EC 2.2.1.6) 0.91 3
Sinorhizobium meliloti 1021 0.25 SMc02765 tryptophan synthase subunit alpha 0.37 SMc01431 acetolactate synthase 3 catalytic subunit 0.75 26
Mucilaginibacter yixingensis YX-36 DSM 26809 0.25 ABZR88_RS10660 tryptophan synthase subunit alpha 0.32 ABZR88_RS11580 biosynthetic-type acetolactate synthase large subunit
Pseudomonas fluorescens FW300-N2E2 0.25 Pf6N2E2_4047 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.35 Pf6N2E2_5175 Acetolactate synthase large subunit (EC 2.2.1.6) 0.94 2
Acinetobacter radioresistens SK82 0.25 MPMX26_02611 Tryptophan synthase alpha chain 0.36 MPMX26_00472 Acetolactate synthase isozyme 3 large subunit
Pseudomonas syringae pv. syringae B728a 0.24 Psyr_0033 tryptophan synthase, alpha chain 0.35 Psyr_0846 acetolactate synthase, large subunit 0.70 2
Pseudomonas syringae pv. syringae B728a ΔmexB 0.24 Psyr_0033 tryptophan synthase, alpha chain 0.35 Psyr_0846 acetolactate synthase, large subunit 0.60 40
Pseudomonas putida KT2440 0.24 PP_0082 tryptophan synthase alpha chain 0.34 PP_4680 acetohydroxybutanoate synthase / acetolactate synthase 0.87 7
Acidovorax sp. GW101-3H11 0.24 Ac3H11_1535 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.35 Ac3H11_525 Acetolactate synthase large subunit (EC 2.2.1.6) 0.84 24
Parabacteroides merdae CL09T00C40 0.23 HMPREF1078_RS00120 tryptophan synthase subunit alpha 0.31 HMPREF1078_RS16690 biosynthetic-type acetolactate synthase large subunit low > 61
Variovorax sp. SCN45 0.23 GFF3882 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.37 GFF1597 Acetolactate synthase large subunit (EC 2.2.1.6)
Dechlorosoma suillum PS 0.23 Dsui_3191 tryptophan synthase, alpha subunit 0.34 Dsui_3529 acetolactate synthase, large subunit, biosynthetic type
Phocaeicola dorei CL03T12C01 0.23 ABI39_RS21075 tryptophan synthase subunit alpha 0.33 ABI39_RS12720 biosynthetic-type acetolactate synthase large subunit 0.82 5
Phocaeicola vulgatus CL09T03C04 0.23 HMPREF1058_RS07200 tryptophan synthase subunit alpha 0.33 HMPREF1058_RS16820 biosynthetic-type acetolactate synthase large subunit 0.84 30
Bosea sp. OAE506 0.23 ABIE41_RS03930 tryptophan synthase subunit alpha 0.37 ABIE41_RS12890 acetolactate synthase 3 large subunit
Bacteroides stercoris CC31F 0.23 HMPREF1181_RS15350 tryptophan synthase subunit alpha 0.32 HMPREF1181_RS08330 biosynthetic-type acetolactate synthase large subunit 0.87 18
Shewanella oneidensis MR-1 0.23 SO3024 trpA tryptophan synthase, alpha subunit (NCBI ptt file) 0.35 SO2279 ilvI acetolactate synthase III, large subunit (NCBI ptt file) low > 76
Serratia liquefaciens MT49 0.22 IAI46_14045 tryptophan synthase subunit alpha 0.36 IAI46_03375 acetolactate synthase 3 large subunit low > 86
Bacteroides thetaiotaomicron VPI-5482 0.22 BT0527 tryptophan synthase alpha chain (NCBI ptt file) 0.32 BT2077 acetolactate synthase large subunit (NCBI ptt file) 0.79 20
Shewanella sp. ANA-3 0.22 Shewana3_1515 trpA tryptophan synthase subunit alpha (RefSeq) 0.35 Shewana3_2269 acetolactate synthase 3 catalytic subunit (RefSeq) low > 73
Cupriavidus basilensis FW507-4G11 0.22 RR42_RS14350 tryptophan synthase alpha chain 0.37 RR42_RS05435 acetolactate synthase 3 catalytic subunit
Azospirillum brasilense Sp245 0.22 AZOBR_RS00520 tryptophan synthase subunit alpha 0.38 AZOBR_RS06560 acetolactate synthase low > 97
Bacteroides ovatus ATCC 8483 0.22 BACOVA_03785 tryptophan synthase, alpha subunit 0.31 BACOVA_03303 acetolactate synthase, large subunit, biosynthetic type 0.94 18
Variovorax sp. OAS795 0.22 ABID97_RS08425 tryptophan synthase subunit alpha 0.35 ABID97_RS14885 acetolactate synthase 3 catalytic subunit
Vibrio cholerae E7946 ATCC 55056 0.22 CSW01_05925 tryptophan synthase subunit alpha 0.37 CSW01_12565 acetolactate synthase 3 large subunit low > 62
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS14490 tryptophan synthase subunit alpha 0.37 ABZR87_RS14955 acetolactate synthase 3 catalytic subunit 0.55 53
Caulobacter crescentus NA1000 Δfur 0.22 CCNA_03657 tryptophan synthase alpha chain 0.39 CCNA_02185 acetolactate synthase large subunit low > 67
Caulobacter crescentus NA1000 0.22 CCNA_03657 tryptophan synthase alpha chain 0.39 CCNA_02185 acetolactate synthase large subunit 0.86 43
Azospirillum sp. SherDot2 0.21 MPMX19_02737 Tryptophan synthase alpha chain 0.37 MPMX19_01776 Acetolactate synthase isozyme 3 large subunit
Brevundimonas sp. GW460-12-10-14-LB2 0.21 A4249_RS11320 tryptophan synthase subunit alpha 0.33 A4249_RS10020 acetolactate synthase 2 catalytic subunit
Ralstonia solanacearum GMI1000 0.21 RS_RS09955 tryptophan synthase subunit alpha 0.38 RS_RS10420 acetolactate synthase 3 large subunit
Pantoea sp. MT58 0.21 IAI47_09165 tryptophan synthase subunit alpha 0.34 IAI47_15990 acetolactate synthase 3 large subunit low > 76
Ralstonia solanacearum PSI07 0.21 RPSI07_RS14740 tryptophan synthase subunit alpha 0.38 RPSI07_RS14255 acetolactate synthase, large subunit, biosynthetic type
Ralstonia solanacearum IBSBF1503 0.21 RALBFv3_RS02575 tryptophan synthase subunit alpha 0.38 RALBFv3_RS03050 acetolactate synthase 3 large subunit
Ralstonia solanacearum UW163 0.21 UW163_RS11150 tryptophan synthase subunit alpha 0.38 UW163_RS10675 acetolactate synthase 3 large subunit
Alteromonas macleodii MIT1002 0.21 MIT1002_01425 Tryptophan synthase alpha chain 0.37 MIT1002_00503 Acetolactate synthase isozyme 3 large subunit
Klebsiella michiganensis M5al 0.21 BWI76_RS11840 tryptophan synthase subunit alpha 0.34 BWI76_RS04695 acetolactate synthase 3 large subunit low > 92
Herbaspirillum seropedicae SmR1 0.21 HSERO_RS16470 tryptophan synthase subunit alpha 0.35 HSERO_RS08650 acetolactate synthase 0.61 17
Paraburkholderia graminis OAS925 0.21 ABIE53_004811 tryptophan synthase alpha chain 0.36 ABIE53_001574 acetolactate synthase-1/2/3 large subunit
Desulfovibrio vulgaris Miyazaki F 0.21 DvMF_1740 trpA tryptophan synthase subunit alpha (RefSeq) 0.37 DvMF_0153 acetolactate synthase, large subunit, biosynthetic type (RefSeq) 0.81 31
Dickeya dianthicola 67-19 0.20 HGI48_RS10460 tryptophan synthase subunit alpha 0.35 HGI48_RS18040 acetolactate synthase 3 large subunit low > 71
Dickeya dianthicola ME23 0.20 DZA65_RS10940 tryptophan synthase subunit alpha 0.35 DZA65_RS19185 acetolactate synthase 3 large subunit low > 75
Dickeya dadantii 3937 0.20 DDA3937_RS10460 tryptophan synthase subunit alpha 0.35 DDA3937_RS18105 acetolactate synthase 3 large subunit low > 74
Shewanella loihica PV-4 0.20 Shew_2256 trpA tryptophan synthase subunit alpha (RefSeq) 0.35 Shew_1776 acetolactate synthase 3 catalytic subunit (RefSeq) low > 60
Xanthomonas campestris pv. campestris strain 8004 0.20 Xcc-8004.1967.1 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.31 Xcc-8004.1059.1 Acetolactate synthase large subunit (EC 2.2.1.6) 0.90 9
Rahnella sp. WP5 0.20 EX31_RS09980 tryptophan synthase subunit alpha 0.36 EX31_RS03665 acetolactate synthase 3 large subunit low > 89
Enterobacter asburiae PDN3 0.20 EX28DRAFT_0932 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.34 EX28DRAFT_3673 acetolactate synthase, large subunit (EC 2.2.1.6) low > 76
Escherichia fergusonii Becca 0.20 EFB2_02666 Tryptophan synthase alpha chain 0.35 EFB2_03969 Acetolactate synthase isozyme 3 large subunit low > 86
Enterobacter sp. TBS_079 0.20 MPMX20_02514 Tryptophan synthase alpha chain 0.34 MPMX20_00771 Acetolactate synthase isozyme 3 large subunit low > 85
Escherichia coli ECOR38 0.19 HEPCGN_25515 trpA tryptophan synthase subunit alpha 0.35 HEPCGN_08680 ilvI acetolactate synthase 3 large subunit low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.19 OHPLBJKB_02423 Tryptophan synthase alpha chain 0.35 OHPLBJKB_03581 Acetolactate synthase isozyme 3 large subunit low > 73
Escherichia coli BW25113 0.19 b1260 trpA tryptophan synthase subunit alpha (NCBI) 0.35 b0077 ilvI acetolactate synthase III large subunit (NCBI) low > 76
Escherichia coli Nissle 1917 0.19 ECOLIN_RS07595 tryptophan synthase subunit alpha 0.35 ECOLIN_RS00415 acetolactate synthase 3 large subunit
Escherichia coli BL21 0.19 ECD_01234 tryptophan synthase, alpha subunit 0.35 ECD_00079 acetolactate synthase 3 large subunit low > 61
Escherichia coli ECOR27 0.19 NOLOHH_20335 trpA tryptophan synthase subunit alpha 0.35 NOLOHH_03045 ilvI acetolactate synthase 3 large subunit low > 75
Escherichia coli ECRC62 0.19 BNILDI_18480 trpA tryptophan synthase subunit alpha 0.35 BNILDI_08565 ilvI acetolactate synthase 3 large subunit low > 75
Pectobacterium carotovorum WPP14 0.19 HER17_RS10940 tryptophan synthase subunit alpha 0.35 HER17_RS03095 acetolactate synthase 3 large subunit low > 75
Erwinia tracheiphila SCR3 0.19 LU632_RS12775 trpA tryptophan synthase subunit alpha 0.34 LU632_RS24415 ilvG acetolactate synthase 2 catalytic subunit low > 74
Paraburkholderia bryophila 376MFSha3.1 0.19 H281DRAFT_06065 tryptophan synthase, alpha chain 0.37 H281DRAFT_04551 acetolactate synthase, large subunit
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.19 GFF2726 Tryptophan synthase alpha chain (EC 4.2.1.20) 0.33 GFF161 Acetolactate synthase large subunit (EC 2.2.1.6) low > 78
Escherichia coli ECRC100 0.19 OKFHMN_02675 trpA tryptophan synthase subunit alpha 0.35 OKFHMN_10700 ilvI acetolactate synthase 3 large subunit low > 80
Escherichia coli ECRC101 0.19 MCAODC_15590 trpA tryptophan synthase subunit alpha 0.35 MCAODC_01215 ilvI acetolactate synthase 3 large subunit low > 87
Escherichia coli ECRC99 0.19 KEDOAH_26075 trpA tryptophan synthase subunit alpha 0.35 KEDOAH_17455 ilvI acetolactate synthase 3 large subunit
Escherichia coli ECRC102 0.19 NIAGMN_26845 trpA tryptophan synthase subunit alpha 0.35 NIAGMN_08550 ilvI acetolactate synthase 3 large subunit
Escherichia coli ECRC98 0.19 JDDGAC_05220 trpA tryptophan synthase subunit alpha 0.35 JDDGAC_14295 ilvI acetolactate synthase 3 large subunit low > 86
Castellaniella sp019104865 MT123 0.19 ABCV34_RS08430 tryptophan synthase subunit alpha 0.35 ABCV34_RS01210 acetolactate synthase 3 catalytic subunit
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS33865 tryptophan synthase alpha chain 0.37 BPHYT_RS06545 acetolactate synthase 0.92 4
Shewanella amazonensis SB2B 0.18 Sama_2134 trpA tryptophan synthase subunit alpha (RefSeq) 0.35 Sama_2018 acetolactate synthase 3 catalytic subunit (RefSeq) low > 62
Paraburkholderia sabiae LMG 24235 0.18 QEN71_RS17655 tryptophan synthase subunit alpha 0.36 QEN71_RS24225 acetolactate synthase 3 catalytic subunit 0.88 17
Sphingomonas koreensis DSMZ 15582 0.18 Ga0059261_0239 tryptophan synthase, alpha chain (EC 4.2.1.20) 0.37 Ga0059261_0068 acetolactate synthase, large subunit (EC 2.2.1.6) 0.88 15

Not shown: 1 genomes with orthologs for BBR_RS15810 only; 11 genomes with orthologs for BBR_RS12350 only