Conservation of cofitness between Atu4096 and Atu4098 in Agrobacterium fabrum C58

91 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu4096 nicotinate-nucleotide pyrophosphorylase 1.0 Atu4098 quinolinate synthetase 0.97 1
Rhizobium sp. OAE497 0.82 ABIE40_RS23265 carboxylating nicotinate-nucleotide diphosphorylase 0.83 ABIE40_RS23255 quinolinate synthase NadA low > 107
Azospirillum sp. SherDot2 0.56 MPMX19_05672 putative nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.61 MPMX19_05670 Quinolinate synthase A — —
Caulobacter crescentus NA1000 Δfur 0.53 CCNA_03009 nicotinate-nucleotide pyrophosphorylase 0.55 CCNA_03006 quinolinate synthetase A — —
Caulobacter crescentus NA1000 0.53 CCNA_03009 nicotinate-nucleotide pyrophosphorylase 0.55 CCNA_03006 quinolinate synthetase A — —
Rhodospirillum rubrum S1H 0.53 Rru_A1432 Nicotinate-nucleotide pyrophosphorylase (NCBI) 0.57 Rru_A1434 Quinolinate synthetase A (NCBI) 0.93 1
Rhodopseudomonas palustris CGA009 0.51 TX73_005415 carboxylating nicotinate-nucleotide diphosphorylase 0.58 TX73_005425 quinolinate synthase NadA — —
Phaeobacter inhibens DSM 17395 0.50 PGA1_c27810 nicotinate-nucleotide pyrophosphorylase 0.53 PGA1_c27790 quinolinate synthetase A 0.86 1
Brevundimonas sp. GW460-12-10-14-LB2 0.49 A4249_RS00635 carboxylating nicotinate-nucleotide diphosphorylase 0.54 A4249_RS00620 quinolinate synthase NadA low > 48
Sinorhizobium meliloti 1021 0.49 SMc02598 nicotinate-nucleotide pyrophosphorylase carboxylating protein 0.56 SMc02601 quinolinate synthetase low > 103
Magnetospirillum magneticum AMB-1 0.48 AMB_RS19655 nicotinate-nucleotide diphosphorylase (carboxylating) 0.30 AMB_RS19660 quinolinate synthase NadA — —
Cupriavidus basilensis FW507-4G11 0.41 RR42_RS21245 nicotinate-nucleotide pyrophosphorylase 0.24 RR42_RS17020 quinolinate synthetase low > 128
Phocaeicola dorei CL03T12C01 0.41 ABI39_RS11900 carboxylating nicotinate-nucleotide diphosphorylase 0.31 ABI39_RS05755 quinolinate synthase NadA — —
Phocaeicola vulgatus CL09T03C04 0.41 HMPREF1058_RS15940 carboxylating nicotinate-nucleotide diphosphorylase 0.31 HMPREF1058_RS11230 quinolinate synthase NadA — —
Mycobacterium tuberculosis H37Rv 0.40 Rv1596 Probable nicotinate-nucleotide pyrophosphatase NadC 0.31 Rv1594 Probable quinolinate synthetase NadA — —
Pedobacter sp. GW460-11-11-14-LB5 0.40 CA265_RS14530 nicotinate-nucleotide diphosphorylase (carboxylating) 0.35 CA265_RS21180 quinolinate synthase — —
Sphingomonas koreensis DSMZ 15582 0.40 Ga0059261_0061 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.31 Ga0059261_0051 quinolinate synthetase (EC 2.5.1.72) — —
Bifidobacterium breve UCC2003 0.40 BBR_RS16720 nicotinate-nucleotide diphosphorylase (carboxylating) 0.23 BBR_RS16730 quinolinate synthase NadA 0.74 1
Mucilaginibacter yixingensis YX-36 DSM 26809 0.39 ABZR88_RS15695 carboxylating nicotinate-nucleotide diphosphorylase 0.36 ABZR88_RS20650 quinolinate synthase NadA — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.39 GFF1217 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.25 GFF1216 Quinolinate synthetase (EC 2.5.1.72) low > 90
Parabacteroides merdae CL09T00C40 0.39 HMPREF1078_RS16725 carboxylating nicotinate-nucleotide diphosphorylase 0.33 HMPREF1078_RS06555 quinolinate synthase NadA — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.39 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.24 Psyr_1542 quinolinate synthetase low > 86
Pseudomonas syringae pv. syringae B728a 0.39 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.24 Psyr_1542 quinolinate synthetase 0.84 1
Rhodanobacter denitrificans MT42 0.38 LRK55_RS13510 carboxylating nicotinate-nucleotide diphosphorylase 0.52 LRK55_RS13615 quinolinate synthase NadA low > 63
Bacteroides stercoris CC31F 0.38 HMPREF1181_RS10745 carboxylating nicotinate-nucleotide diphosphorylase 0.35 HMPREF1181_RS01920 quinolinate synthase NadA — —
Bacteroides ovatus ATCC 8483 0.38 BACOVA_04303 nicotinate-nucleotide diphosphorylase (carboxylating) 0.34 BACOVA_02839 quinolinate synthetase complex, A subunit 0.83 39
Pseudomonas simiae WCS417 0.38 PS417_03925 nicotinate-nucleotide pyrophosphorylase 0.22 PS417_22385 quinolinate synthase A 0.88 1
Pseudomonas fluorescens FW300-N1B4 0.38 Pf1N1B4_1153 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.23 Pf1N1B4_626 Quinolinate synthetase (EC 2.5.1.72) 0.78 1
Bacteroides thetaiotaomicron VPI-5482 0.38 BT1560 nicotinate-nucleotide pyrophosphorylase (NCBI ptt file) 0.34 BT3164 quinolinate synthetase A (NCBI ptt file) — —
Pseudomonas sp. RS175 0.38 PFR28_00098 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.23 PFR28_03388 Quinolinate synthase A 0.95 1
Rhodanobacter denitrificans FW104-10B01 0.38 LRK54_RS13795 carboxylating nicotinate-nucleotide diphosphorylase 0.52 LRK54_RS13900 quinolinate synthase NadA low > 59
Ralstonia sp. UNC404CL21Col 0.38 ABZR87_RS00350 carboxylating nicotinate-nucleotide diphosphorylase 0.26 ABZR87_RS00355 quinolinate synthase NadA 0.95 1
Pseudomonas fluorescens SBW25 0.38 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase 0.22 PFLU_RS24025 quinolinate synthase NadA 0.91 1
Pseudomonas fluorescens SBW25-INTG 0.38 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase 0.22 PFLU_RS24025 quinolinate synthase NadA 0.94 1
Dechlorosoma suillum PS 0.37 Dsui_2901 nicotinate-nucleotide pyrophosphorylase 0.21 Dsui_1043 quinolinate synthetase complex, A subunit — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.37 GFF130 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.23 GFF4 Quinolinate synthetase (EC 2.5.1.72) — —
Dickeya dadantii 3937 0.37 DDA3937_RS17955 carboxylating nicotinate-nucleotide diphosphorylase 0.22 DDA3937_RS06545 quinolinate synthase NadA 0.92 3
Pseudomonas stutzeri RCH2 0.37 Psest_0718 nicotinate-nucleotide pyrophosphorylase 0.24 Psest_1509 quinolinate synthetase complex, A subunit 0.77 1
Fusobacterium nucleatum SB010 0.36 HUW76_10730 carboxylating nicotinate-nucleotide diphosphorylase 0.25 HUW76_10740 quinolinate synthase NadA low > 35
Ralstonia solanacearum IBSBF1503 0.36 RALBFv3_RS04730 nicotinate-nucleotide diphosphorylase (carboxylating) 0.24 RALBFv3_RS04735 quinolinate synthase NadA low > 76
Pseudomonas putida KT2440 0.36 PP_0787 quinolinate phosphoribosyltransferase (decarboxylating) monomer 0.23 PP_1231 quinolinate synthase [4Fe-4S] cluster subunit 0.89 1
Ralstonia solanacearum UW163 0.36 UW163_RS08940 nicotinate-nucleotide diphosphorylase (carboxylating) 0.24 UW163_RS08935 quinolinate synthase NadA — —
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_05520 nicotinate-nucleotide pyrophosphorylase 0.22 AO353_03525 quinolinate synthase A 0.90 1
Alteromonas macleodii MIT1002 0.36 MIT1002_03008 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.23 MIT1002_01344 Quinolinate synthase A — —
Acidovorax sp. GW101-3H11 0.36 Ac3H11_3838 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.25 Ac3H11_3837 Quinolinate synthetase (EC 2.5.1.72) 0.97 1
Dickeya dianthicola 67-19 0.36 HGI48_RS17890 carboxylating nicotinate-nucleotide diphosphorylase 0.21 HGI48_RS06595 quinolinate synthase NadA 0.62 25
Marinobacter adhaerens HP15 0.36 HP15_1305 nicotinate-nucleotide pyrophosphorylase 0.24 HP15_2032 quinolinate synthetase complex, A subunit — —
Ralstonia solanacearum PSI07 0.36 RPSI07_RS12655 nicotinate-nucleotide diphosphorylase (carboxylating) 0.25 RPSI07_RS12650 quinolinate synthase NadA 0.48 66
Dickeya dianthicola ME23 0.35 DZA65_RS19035 carboxylating nicotinate-nucleotide diphosphorylase 0.21 DZA65_RS06945 quinolinate synthase NadA 0.90 2
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_5082 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.23 PfGW456L13_1863 Quinolinate synthetase (EC 2.5.1.72) 0.94 1
Pectobacterium carotovorum WPP14 0.35 HER17_RS03250 carboxylating nicotinate-nucleotide diphosphorylase 0.23 HER17_RS14820 quinolinate synthase NadA 0.96 2
Paraburkholderia sabiae LMG 24235 0.35 QEN71_RS03065 carboxylating nicotinate-nucleotide diphosphorylase 0.24 QEN71_RS03060 quinolinate synthase NadA 0.97 1
Pseudomonas fluorescens FW300-N2E2 0.35 Pf6N2E2_3346 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.23 Pf6N2E2_5553 Quinolinate synthetase (EC 2.5.1.72) 0.86 1
Pseudomonas fluorescens FW300-N2C3 0.35 AO356_07370 nicotinate-nucleotide pyrophosphorylase 0.23 AO356_18145 quinolinate synthase A 0.82 1
Herbaspirillum seropedicae SmR1 0.35 HSERO_RS11070 nicotinate-nucleotide pyrophosphorylase 0.24 HSERO_RS11065 quinolinate synthetase 0.87 1
Vibrio cholerae E7946 ATCC 55056 0.35 CSW01_12265 carboxylating nicotinate-nucleotide diphosphorylase 0.23 CSW01_09180 quinolinate synthase low > 62
Enterobacter asburiae PDN3 0.35 EX28DRAFT_3702 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.23 EX28DRAFT_2245 quinolinate synthetase (EC 2.5.1.72) 0.64 11
Shewanella amazonensis SB2B 0.35 Sama_0371 nicotinate-nucleotide diphosphorylase (carboxylating) (RefSeq) 0.24 Sama_1712 quinolinate synthetase (RefSeq) — —
Pseudomonas sp. S08-1 0.35 OH686_16520 nicotinate-nucleotide diphosphorylase (carboxylating) 0.24 OH686_19190 quinolinate synthetase complex, A subunit 0.97 1
Castellaniella sp019104865 MT123 0.34 ABCV34_RS03695 carboxylating nicotinate-nucleotide diphosphorylase 0.25 ABCV34_RS03700 quinolinate synthase NadA low > 48
Ralstonia solanacearum GMI1000 0.34 RS_RS12290 nicotinate-nucleotide diphosphorylase (carboxylating) 0.26 RS_RS12295 quinolinate synthase 0.84 1
Klebsiella michiganensis M5al 0.34 BWI76_RS04845 nicotinate-nucleotide pyrophosphorylase 0.23 BWI76_RS08580 quinolinate synthetase 0.83 2
Enterobacter sp. TBS_079 0.34 MPMX20_00800 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.22 MPMX20_01377 Quinolinate synthase A 0.65 2
Rahnella sp. WP5 0.34 EX31_RS03515 carboxylating nicotinate-nucleotide diphosphorylase 0.22 EX31_RS23525 quinolinate synthase NadA 0.57 21
Kangiella aquimarina DSM 16071 0.34 B158DRAFT_2135 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.23 B158DRAFT_2453 quinolinate synthetase (EC 2.5.1.72) — —
Variovorax sp. OAS795 0.34 ABID97_RS07410 carboxylating nicotinate-nucleotide diphosphorylase 0.24 ABID97_RS07415 quinolinate synthase NadA 0.97 1
Escherichia coli HS(pFamp)R (ATCC 700891) 0.33 OHPLBJKB_03552 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.23 OHPLBJKB_02963 Quinolinate synthase A low > 73
Shewanella loihica PV-4 0.33 Shew_3435 nicotinate-nucleotide pyrophosphorylase (RefSeq) 0.23 Shew_1928 quinolinate synthetase (RefSeq) — —
Escherichia coli BW25113 0.33 b0109 nadC nicotinate-nucleotide pyrophosphorylase (NCBI) 0.24 b0750 nadA quinolinate synthetase (NCBI) 0.88 1
Escherichia coli ECOR27 0.33 NOLOHH_02875 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.24 NOLOHH_23190 nadA quinolinate synthase NadA low > 57
Escherichia coli BL21 0.33 ECD_00108 quinolinate phosphoribosyltransferase 0.24 ECD_00703 quinolinate synthase, subunit A low > 60
Escherichia coli ECRC101 0.33 MCAODC_01045 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.23 MCAODC_25980 nadA quinolinate synthase NadA — —
Escherichia coli ECRC101 0.33 OKFHMN_10530 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.23 OKFHMN_06760 nadA quinolinate synthase NadA — —
Escherichia coli Nissle 1917 0.33 ECOLIN_RS00585 carboxylating nicotinate-nucleotide diphosphorylase 0.23 ECOLIN_RS03990 quinolinate synthase NadA low > 52
Burkholderia phytofirmans PsJN 0.33 BPHYT_RS15645 nicotinate-nucleotide pyrophosphorylase 0.23 BPHYT_RS15650 quinolinate synthetase 0.94 1
Escherichia coli ECOR38 0.33 HEPCGN_08510 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.24 HEPCGN_01515 nadA quinolinate synthase NadA low > 85
Escherichia coli ECRC62 0.33 BNILDI_08735 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.24 BNILDI_21185 nadA quinolinate synthase NadA — —
Escherichia coli ECRC99 0.33 KEDOAH_17625 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.23 KEDOAH_21205 nadA quinolinate synthase NadA — —
Escherichia fergusonii Becca 0.33 EFB2_03940 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.23 EFB2_03356 Quinolinate synthase A low > 86
Escherichia coli ECRC98 0.33 JDDGAC_14125 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.23 JDDGAC_10415 nadA quinolinate synthase NadA — —
Escherichia coli ECRC102 0.33 NIAGMN_08380 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.23 NIAGMN_04810 nadA quinolinate synthase NadA — —
Variovorax sp. SCN45 0.33 GFF2574 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.24 GFF2575 Quinolinate synthetase (EC 2.5.1.72) 0.91 1
Synechococcus elongatus PCC 7942 0.33 Synpcc7942_0951 nadC nicotinate-nucleotide pyrophosphorylase 0.32 Synpcc7942_1448 nadA quinolinate synthetase 0.80 1
Paraburkholderia graminis OAS925 0.33 ABIE53_003293 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.24 ABIE53_003294 quinolinate synthase 0.88 1
Acinetobacter radioresistens SK82 0.32 MPMX26_00042 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.24 MPMX26_02602 Quinolinate synthase A 0.75 1
Serratia liquefaciens MT49 0.32 IAI46_03530 carboxylating nicotinate-nucleotide diphosphorylase 0.23 IAI46_06380 quinolinate synthase NadA low > 86
Pantoea sp. MT58 0.32 IAI47_15845 carboxylating nicotinate-nucleotide diphosphorylase 0.23 IAI47_13635 quinolinate synthase NadA 0.78 1
Shewanella sp. ANA-3 0.31 Shewana3_0422 nicotinate-nucleotide pyrophosphorylase [carboxylating] (RefSeq) 0.22 Shewana3_2128 quinolinate synthetase (RefSeq) — —
Desulfovibrio vulgaris Hildenborough JW710 0.31 DVU1807 nadC nicotinate-nucleotide pyrophosphorylase (TIGR) 0.18 DVU1808 nadA quinolinate synthetase complex, subunit A (TIGR) — —
Methanococcus maripaludis S2 0.30 MMP_RS04560 carboxylating nicotinate-nucleotide diphosphorylase 0.31 MMP_RS06390 quinolinate synthase NadA — —
Desulfovibrio vulgaris Miyazaki F 0.30 DvMF_0524 nicotinate-nucleotide pyrophosphorylase (RefSeq) 0.19 DvMF_0525 quinolinate synthetase (RefSeq) — —
Methanococcus maripaludis JJ 0.29 MMJJ_RS00575 carboxylating nicotinate-nucleotide diphosphorylase 0.31 MMJJ_RS07960 quinolinate synthase NadA — —

Not shown: 8 genomes with orthologs for Atu4096 only; 3 genomes with orthologs for Atu4098 only