Conservation of cofitness between b0074 and b3770 in Escherichia coli BW25113

88 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0074 leuA 2-isopropylmalate synthase (NCBI) 1.0 b3770 ilvE branched-chain amino acid aminotransferase (NCBI) 0.97 6
Escherichia coli BL21 1.00 ECD_00076 2-isopropylmalate synthase 1.00 ECD_03648 branched-chain amino acid aminotransferase 0.81 1
Escherichia coli ECOR27 1.00 NOLOHH_03060 2-isopropylmalate synthase 1.00 NOLOHH_06780 ilvE branched-chain-amino-acid transaminase low > 57
Escherichia coli ECRC62 1.00 BNILDI_08550 2-isopropylmalate synthase 1.00 BNILDI_04745 ilvE branched-chain-amino-acid transaminase — —
Escherichia fergusonii Becca 1.00 EFB2_03971 2-isopropylmalate synthase 1.00 EFB2_04866 Branched-chain-amino-acid aminotransferase low > 86
Escherichia coli ECOR38 1.00 HEPCGN_08695 2-isopropylmalate synthase 1.00 HEPCGN_13355 ilvE branched-chain-amino-acid transaminase low > 85
Escherichia coli Nissle 1917 1.00 ECOLIN_RS00400 2-isopropylmalate synthase 1.00 ECOLIN_RS21660 branched-chain-amino-acid transaminase low > 52
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03583 2-isopropylmalate synthase 1.00 OHPLBJKB_04283 Branched-chain-amino-acid aminotransferase low > 73
Escherichia coli ECRC101 1.00 OKFHMN_10715 2-isopropylmalate synthase 1.00 OKFHMN_14645 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC102 1.00 NIAGMN_08565 2-isopropylmalate synthase 1.00 NIAGMN_12400 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC98 1.00 JDDGAC_14310 2-isopropylmalate synthase 1.00 JDDGAC_18265 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC99 1.00 KEDOAH_17440 2-isopropylmalate synthase 1.00 KEDOAH_13505 ilvE branched-chain-amino-acid transaminase — —
Escherichia coli ECRC101 1.00 MCAODC_01230 2-isopropylmalate synthase 1.00 MCAODC_05150 ilvE branched-chain-amino-acid transaminase — —
Klebsiella michiganensis M5al 0.95 BWI76_RS04680 2-isopropylmalate synthase 0.97 BWI76_RS00970 branched chain amino acid aminotransferase 0.56 84
Enterobacter asburiae PDN3 0.94 EX28DRAFT_3670 2-isopropylmalate synthase (EC 2.3.3.13) 0.98 EX28DRAFT_4442 branched-chain amino acid aminotransferase, group I 0.96 3
Enterobacter sp. TBS_079 0.94 MPMX20_00769 2-isopropylmalate synthase 0.99 MPMX20_04500 Branched-chain-amino-acid aminotransferase low > 85
Pectobacterium carotovorum WPP14 0.87 HER17_RS03085 2-isopropylmalate synthase 0.90 HER17_RS01070 branched-chain amino acid transaminase low > 75
Erwinia tracheiphila SCR3 0.86 LU632_RS02880 leuA 2-isopropylmalate synthase 0.90 LU632_RS24405 branched-chain amino acid transaminase 0.96 1
Dickeya dianthicola 67-19 0.86 HGI48_RS18055 2-isopropylmalate synthase 0.90 HGI48_RS20300 branched-chain-amino-acid transaminase low > 71
Dickeya dadantii 3937 0.86 DDA3937_RS18115 2-isopropylmalate synthase 0.91 DDA3937_RS20160 branched-chain-amino-acid transaminase 0.74 40
Dickeya dianthicola ME23 0.86 DZA65_RS19200 2-isopropylmalate synthase 0.91 DZA65_RS21340 branched-chain amino acid transaminase 0.88 16
Serratia liquefaciens MT49 0.85 IAI46_03355 2-isopropylmalate synthase 0.92 IAI46_24350 branched-chain-amino-acid transaminase low > 86
Pantoea sp. MT58 0.84 IAI47_16000 2-isopropylmalate synthase 0.91 IAI47_01030 branched-chain amino acid transaminase 0.98 6
Rahnella sp. WP5 0.82 EX31_RS03680 2-isopropylmalate synthase 0.90 EX31_RS15000 branched-chain amino acid transaminase 0.94 39
Vibrio cholerae E7946 ATCC 55056 0.69 CSW01_12595 2-isopropylmalate synthase 0.75 CSW01_00145 branched-chain-amino-acid transaminase low > 62
Shewanella amazonensis SB2B 0.67 Sama_0335 2-isopropylmalate synthase (RefSeq) 0.19 Sama_3299 branched-chain amino acid aminotransferase (RefSeq) low > 62
Shewanella sp. ANA-3 0.66 Shewana3_3761 2-isopropylmalate synthase (RefSeq) 0.19 Shewana3_3830 branched-chain amino acid aminotransferase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.66 SO4236 leuA 2-isopropylmalate synthase (NCBI ptt file) 0.19 SO0340 ilvE branched-chain amino acid aminotransferase (NCBI ptt file) 0.87 69
Shewanella loihica PV-4 0.66 Shew_3472 2-isopropylmalate synthase (RefSeq) 0.68 Shew_0291 branched-chain amino acid aminotransferase (RefSeq) 0.93 38
Alteromonas macleodii MIT1002 0.62 MIT1002_00949 2-isopropylmalate synthase 0.17 MIT1002_00377 Branched-chain-amino-acid aminotransferase 2 0.97 23
Pseudomonas stutzeri RCH2 0.47 Psest_1056 2-isopropylmalate synthase, bacterial type 0.46 Psest_0450 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 67
Dechlorosoma suillum PS 0.46 Dsui_3519 2-isopropylmalate synthase, bacterial type 0.47 Dsui_2030 branched-chain amino acid aminotransferase, group I low > 51
Marinobacter adhaerens HP15 0.45 HP15_538 2-isopropylmalate synthase 0.43 HP15_436 branched-chain-amino-acid aminotransferase — —
Desulfovibrio vulgaris Miyazaki F 0.44 DvMF_1791 2-isopropylmalate synthase (RefSeq) 0.46 DvMF_2268 branched-chain amino acid aminotransferase (RefSeq) low > 51
Phocaeicola vulgatus CL09T03C04 0.44 HMPREF1058_RS14545 2-isopropylmalate synthase 0.18 HMPREF1058_RS02220 branched-chain amino acid aminotransferase 0.81 37
Phocaeicola dorei CL03T12C01 0.44 ABI39_RS10195 2-isopropylmalate synthase 0.18 ABI39_RS01415 branched-chain amino acid aminotransferase 0.61 69
Desulfovibrio vulgaris Hildenborough JW710 0.43 DVU2981 leuA 2-isopropylmalate synthase (TIGR) 0.46 DVU3197 ilvE branched-chain amino acid aminotransferase (TIGR) 0.94 4
Parabacteroides merdae CL09T00C40 0.43 HMPREF1078_RS16665 2-isopropylmalate synthase 0.19 HMPREF1078_RS07855 branched-chain amino acid aminotransferase low > 61
Bacteroides stercoris CC31F 0.42 HMPREF1181_RS14150 2-isopropylmalate synthase 0.19 HMPREF1181_RS06865 branched-chain amino acid aminotransferase low > 56
Paraburkholderia bryophila 376MFSha3.1 0.42 H281DRAFT_04556 2-isopropylmalate synthase 0.43 H281DRAFT_04193 branched chain amino acid aminotransferase apoenzyme low > 103
Magnetospirillum magneticum AMB-1 0.42 AMB_RS17765 2-isopropylmalate synthase 0.31 AMB_RS02850 branched-chain amino acid aminotransferase — —
Ralstonia solanacearum PSI07 0.42 RPSI07_RS14285 2-isopropylmalate synthase 0.45 RPSI07_RS21175 branched-chain amino acid transaminase low > 81
Paraburkholderia graminis OAS925 0.42 ABIE53_001580 2-isopropylmalate synthase 0.43 ABIE53_003432 branched-chain amino acid aminotransferase low > 113
Ralstonia solanacearum UW163 0.42 UW163_RS10700 2-isopropylmalate synthase 0.46 UW163_RS01455 branched-chain amino acid transaminase — —
Ralstonia solanacearum GMI1000 0.42 RS_RS10395 2-isopropylmalate synthase 0.45 RS_RS02840 branched-chain amino acid transaminase low > 80
Ralstonia solanacearum IBSBF1503 0.42 RALBFv3_RS03025 2-isopropylmalate synthase 0.46 RALBFv3_RS12155 branched-chain amino acid transaminase low > 76
Burkholderia phytofirmans PsJN 0.42 BPHYT_RS06570 2-isopropylmalate synthase 0.43 BPHYT_RS16285 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 109
Ralstonia sp. UNC404CL21Col 0.42 ABZR87_RS14930 2-isopropylmalate synthase 0.25 ABZR87_RS18540 branched-chain amino acid aminotransferase low > 80
Bacteroides ovatus ATCC 8483 0.42 BACOVA_04604 2-isopropylmalate synthase 0.30 BACOVA_03679 branched-chain-amino-acid transaminase low > 94
Bacteroides thetaiotaomicron VPI-5482 0.42 BT1861 2-isopropylmalate synthase (EC 2.3.3.13) (from data) 0.19 BT3892 branched-chain amino acid aminotransferase (NCBI ptt file) — —
Paraburkholderia sabiae LMG 24235 0.42 QEN71_RS24195 2-isopropylmalate synthase 0.44 QEN71_RS02410 branched-chain amino acid transaminase low > 153
Rhodopseudomonas palustris CGA009 0.42 TX73_010545 2-isopropylmalate synthase 0.18 TX73_022650 branched-chain amino acid aminotransferase — —
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS05465 2-isopropylmalate synthase 0.20 RR42_RS25890 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 128
Bosea sp. OAE506 0.41 ABIE41_RS13000 2-isopropylmalate synthase 0.28 ABIE41_RS11405 branched-chain amino acid aminotransferase low > 77
Hydrogenophaga sp. GW460-11-11-14-LB1 0.41 GFF4281 2-isopropylmalate synthase (EC 2.3.3.13) 0.46 GFF1835 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 90
Synechococcus elongatus PCC 7942 0.41 Synpcc7942_1410 leuA 2-isopropylmalate synthase 0.29 Synpcc7942_1029 ilvE branched-chain amino acid aminotransferase — —
Dyella japonica UNC79MFTsu3.2 0.41 ABZR86_RS15970 2-isopropylmalate synthase 0.56 ABZR86_RS15965 branched-chain amino acid transaminase 0.98 5
Variovorax sp. OAS795 0.41 ABID97_RS14910 2-isopropylmalate synthase 0.44 ABID97_RS03790 branched-chain amino acid transaminase low > 91
Acidovorax sp. GW101-3H11 0.41 Ac3H11_530 2-isopropylmalate synthase (EC 2.3.3.13) 0.46 Ac3H11_3369 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 79
Variovorax sp. SCN45 0.41 GFF1165 2-isopropylmalate synthase (EC 2.3.3.13) 0.44 GFF5079 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 127
Caulobacter crescentus NA1000 0.40 CCNA_01610 2-isopropylmalate synthase 0.31 CCNA_03024 branched-chain amino acid aminotransferase low > 66
Caulobacter crescentus NA1000 Δfur 0.40 CCNA_01610 2-isopropylmalate synthase 0.31 CCNA_03024 branched-chain amino acid aminotransferase low > 67
Lysobacter sp. OAE881 0.40 ABIE51_RS17570 2-isopropylmalate synthase 0.55 ABIE51_RS16505 branched-chain amino acid transaminase low > 62
Phaeobacter inhibens DSM 17395 0.40 PGA1_c26470 2-isopropylmalate synthase LeuA 0.29 PGA1_c34110 branched-chain-amino-acid aminotransferase IlvE 0.85 24
Rhodanobacter denitrificans FW104-10B01 0.39 LRK54_RS10345 2-isopropylmalate synthase 0.56 LRK54_RS12020 branched-chain amino acid transaminase low > 59
Rhodanobacter denitrificans MT42 0.39 LRK55_RS09985 2-isopropylmalate synthase 0.56 LRK55_RS11755 branched-chain amino acid transaminase low > 63
Xanthomonas campestris pv. campestris strain 8004 0.39 Xcc-8004.1056.1 2-isopropylmalate synthase (EC 2.3.3.13) 0.19 Xcc-8004.4199.1 Branched-chain amino acid aminotransferase (EC 2.6.1.42) 0.69 41
Rhodanobacter sp. FW510-T8 0.38 OKGIIK_13575 leuA 2-isopropylmalate synthase 0.56 OKGIIK_11840 ilvE branched-chain amino acid transaminase low > 52
Dinoroseobacter shibae DFL-12 0.38 Dshi_0596 2-isopropylmalate synthase (RefSeq) 0.26 Dshi_3301 branched-chain amino acid aminotransferase (RefSeq) — —
Methanococcus maripaludis JJ 0.29 MMJJ_RS08870 2-isopropylmalate synthase 0.31 MMJJ_RS04725 branched-chain-amino-acid transaminase low > 28
Methanococcus maripaludis S2 0.28 MMP_RS05500 2-isopropylmalate synthase 0.31 MMP_RS00760 branched-chain-amino-acid transaminase low > 25
Sinorhizobium meliloti 1021 0.15 SMc02546 alpha-isopropylmalate/homocitrate synthase family transferase 0.21 SMc02896 branched-chain amino acid aminotransferase low > 103
Rhizobium sp. OAE497 0.15 ABIE40_RS06220 citramalate synthase 0.19 ABIE40_RS22240 branched-chain amino acid aminotransferase low > 107
Pseudomonas sp. S08-1 0.12 OH686_17570 2-isopropylmalate synthase 0.46 OH686_09695 branched-chain amino acid aminotransferase low > 80
Sphingomonas koreensis DSMZ 15582 0.12 Ga0059261_4031 2-isopropylmalate synthase, yeast type 0.23 Ga0059261_3811 branched-chain amino acid aminotransferase, group II 0.99 13
Pseudomonas fluorescens FW300-N2C3 0.11 AO356_06550 2-isopropylmalate synthase 0.21 AO356_22970 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) low > 104
Pseudomonas fluorescens FW300-N2E2 0.11 Pf6N2E2_3170 2-isopropylmalate synthase (EC 2.3.3.13) 0.21 Pf6N2E2_477 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 103
Acinetobacter radioresistens SK82 0.10 MPMX26_00404 2-isopropylmalate synthase 0.40 MPMX26_00445 Branched-chain-amino-acid aminotransferase 0.93 3
Pseudomonas sp. RS175 0.10 PFR28_00305 2-isopropylmalate synthase 0.21 PFR28_02449 putative branched-chain-amino-acid aminotransferase low > 88
Castellaniella sp019104865 MT123 0.10 ABCV34_RS12420 2-isopropylmalate synthase 0.45 ABCV34_RS07930 branched-chain amino acid transaminase low > 48
Pseudomonas fluorescens GW456-L13 0.10 PfGW456L13_4854 2-isopropylmalate synthase (EC 2.3.3.13) 0.27 PfGW456L13_4923 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 87
Pseudomonas fluorescens FW300-N1B4 0.10 Pf1N1B4_847 2-isopropylmalate synthase (EC 2.3.3.13) 0.22 Pf1N1B4_4476 Branched-chain amino acid aminotransferase (EC 2.6.1.42) low > 87
Agrobacterium fabrum C58 0.10 Atu2264 2-isopropylmalate synthase 0.18 Atu0871 branched-chain-amino-acid aminotransferase low > 89
Pseudomonas putida KT2440 0.10 PP_1025 2-isopropylmalate synthase 0.19 PP_3511 Branched-chain-amino-acid aminotransferase 0.84 14
Pseudomonas simiae WCS417 0.10 PS417_23110 2-isopropylmalate synthase 0.21 PS417_17565 branched-chain amino acid aminotransferase low > 88
Pseudomonas fluorescens SBW25-INTG 0.10 PFLU_RS24765 2-isopropylmalate synthase 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase low > 109
Pseudomonas fluorescens SBW25 0.10 PFLU_RS24765 2-isopropylmalate synthase 0.21 PFLU_RS19375 branched-chain amino acid aminotransferase 0.52 43
Pseudomonas syringae pv. syringae B728a 0.10 Psyr_1257 2-isopropylmalate synthase 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme 0.72 39
Pseudomonas syringae pv. syringae B728a ΔmexB 0.10 Psyr_1257 2-isopropylmalate synthase 0.22 Psyr_1148 branched chain amino acid aminotransferase apoenzyme low > 86

Not shown: 0 genomes with orthologs for b0074 only; 14 genomes with orthologs for b3770 only