Conservation of cofitness between b0945 and b4005 in Escherichia coli BW25113

92 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 1.0 b4005 purD phosphoribosylamine--glycine ligase (NCBI) 0.90 8
Escherichia coli BL21 1.00 ECD_00949 dihydro-orotate oxidase, FMN-linked 0.98 ECD_03882 phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase 0.79 8
Escherichia coli ECOR27 1.00 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase 0.99 NOLOHH_05460 purD Phosphoribosylamine--glycine ligase 0.94 7
Escherichia coli ECRC99 1.00 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase 0.98 KEDOAH_14845 purD Phosphoribosylamine--glycine ligase
Escherichia coli ECRC101 1.00 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 0.98 MCAODC_03815 purD Phosphoribosylamine--glycine ligase low > 87
Escherichia coli ECRC102 1.00 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.98 NIAGMN_11065 purD Phosphoribosylamine--glycine ligase
Escherichia coli ECRC62 1.00 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.99 BNILDI_06060 purD Phosphoribosylamine--glycine ligase 0.92 13
Escherichia coli ECRC98 1.00 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase 0.98 JDDGAC_16940 purD Phosphoribosylamine--glycine ligase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) 0.99 OHPLBJKB_04044 Phosphoribosylamine--glycine ligase 0.64 8
Escherichia coli ECRC100 1.00 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase 0.98 OKFHMN_13315 purD Phosphoribosylamine--glycine ligase 0.86 25
Escherichia coli ECOR38 1.00 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase 0.98 HEPCGN_11955 purD Phosphoribosylamine--glycine ligase 0.92 4
Escherichia coli Nissle 1917 0.99 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase 0.98 ECOLIN_RS23095 phosphoribosylamine--glycine ligase
Escherichia fergusonii Becca 0.99 EFB2_03126 Dihydroorotate dehydrogenase (quinone) 0.98 EFB2_04605 Phosphoribosylamine--glycine ligase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.93 GFF4187 Phosphoribosylamine--glycine ligase (EC 6.3.4.13) low > 78
Enterobacter sp. TBS_079 0.94 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.92 MPMX20_00225 Phosphoribosylamine--glycine ligase 0.85 15
Enterobacter asburiae PDN3 0.94 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) 0.92 EX28DRAFT_4544 phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Klebsiella michiganensis M5al 0.93 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.92 BWI76_RS01610 phosphoribosylamine--glycine ligase 0.66 12
Serratia liquefaciens MT49 0.87 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.81 IAI46_01360 phosphoribosylamine--glycine ligase low > 86
Rahnella sp. WP5 0.86 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.82 EX31_RS16855 phosphoribosylamine--glycine ligase 0.93 25
Dickeya dianthicola ME23 0.86 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.83 DZA65_RS01255 phosphoribosylamine--glycine ligase low > 75
Pectobacterium carotovorum WPP14 0.86 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.82 HER17_RS20340 phosphoribosylamine--glycine ligase 0.92 48
Dickeya dadantii 3937 0.86 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.83 DDA3937_RS01215 phosphoribosylamine--glycine ligase 0.76 10
Dickeya dianthicola 67-19 0.85 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.83 HGI48_RS01210 phosphoribosylamine--glycine ligase 0.86 4
Erwinia tracheiphila SCR3 0.84 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.81 LU632_RS01015 purD phosphoribosylamine--glycine ligase 0.90 11
Pantoea sp. MT58 0.81 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.84 IAI47_18045 phosphoribosylamine--glycine ligase 0.97 7
Vibrio cholerae E7946 ATCC 55056 0.72 CSW01_07490 dihydroorotate dehydrogenase (quinone) 0.79 CSW01_01415 phosphoribosylamine--glycine ligase 0.39 59
Shewanella sp. ANA-3 0.63 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.70 Shewana3_0440 phosphoribosylamine--glycine ligase (RefSeq) 0.83 53
Shewanella loihica PV-4 0.63 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) 0.67 Shew_3413 phosphoribosylamine--glycine ligase (RefSeq) low > 60
Shewanella amazonensis SB2B 0.62 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) 0.71 Sama_0394 phosphoribosylamine--glycine ligase (RefSeq) 0.64 25
Shewanella oneidensis MR-1 0.62 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) 0.68 SO0441 purD phosphoribosylamine--glycine ligase (NCBI ptt file) 0.87 22
Alteromonas macleodii MIT1002 0.58 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) 0.72 MIT1002_03961 Phosphoribosylamine--glycine ligase low > 70
Pseudomonas fluorescens SBW25 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.73 PFLU_RS03010 phosphoribosylamine--glycine ligase
Pseudomonas fluorescens SBW25-INTG 0.57 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.73 PFLU_RS03010 phosphoribosylamine--glycine ligase
Pseudomonas fluorescens FW300-N1B4 0.57 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.73 Pf1N1B4_1316 Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Paraburkholderia sabiae LMG 24235 0.57 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase 0.58 QEN71_RS24400 phosphoribosylamine--glycine ligase
Pseudomonas fluorescens FW300-N2E3 0.57 AO353_00780 dihydroorotate dehydrogenase (quinone) 0.73 AO353_13645 phosphoribosylamine--glycine ligase
Burkholderia phytofirmans PsJN 0.57 BPHYT_RS08565 dihydroorotate dehydrogenase 0.59 BPHYT_RS06405 phosphoribosylamine--glycine ligase 0.73 7
Pseudomonas simiae WCS417 0.57 PS417_20935 dihydroorotate dehydrogenase 0.72 PS417_02935 phosphoribosylamine--glycine ligase
Pseudomonas syringae pv. syringae B728a 0.57 Psyr_2106 dihydroorotate oxidase A 0.73 Psyr_4407 phosphoribosylamine--glycine ligase
Pseudomonas syringae pv. syringae B728a ΔmexB 0.57 Psyr_2106 dihydroorotate oxidase A 0.73 Psyr_4407 phosphoribosylamine--glycine ligase
Paraburkholderia graminis OAS925 0.56 ABIE53_001954 dihydroorotate dehydrogenase 0.59 ABIE53_001545 phosphoribosylamine--glycine ligase
Pseudomonas sp. RS175 0.56 PFR28_01054 Dihydroorotate dehydrogenase (quinone) 0.73 PFR28_05213 Phosphoribosylamine--glycine ligase
Pseudomonas fluorescens FW300-N2E2 0.56 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.73 Pf6N2E2_3520 Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Pseudomonas fluorescens GW456-L13 0.56 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.72 PfGW456L13_58 Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Pseudomonas fluorescens FW300-N2C3 0.56 AO356_02610 dihydroorotate dehydrogenase (quinone) 0.73 AO356_08230 phosphoribosylamine--glycine ligase
Pseudomonas sp. S08-1 0.55 OH686_03120 dihydroorotate dehydrogenase (fumarate) 0.72 OH686_07625 Phosphoribosylamine--glycine ligase
Dechlorosoma suillum PS 0.55 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 0.62 Dsui_1596 phosphoribosylamine--glycine ligase
Kangiella aquimarina DSM 16071 0.55 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) 0.71 B158DRAFT_0167 phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Pseudomonas stutzeri RCH2 0.55 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 0.73 Psest_1013 phosphoribosylamine--glycine ligase 0.65 7
Paraburkholderia bryophila 376MFSha3.1 0.55 H281DRAFT_00743 dihydroorotate oxidase A 0.59 H281DRAFT_04521 phosphoribosylamine--glycine ligase
Ralstonia sp. UNC404CL21Col 0.54 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase 0.58 ABZR87_RS15410 phosphoribosylamine--glycine ligase
Pseudomonas putida KT2440 0.54 PP_2095 Dihydroorotate dehydrogenase (quinone) 0.74 PP_4823 Phosphoribosylamine--glycine ligase
Ralstonia solanacearum UW163 0.54 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase 0.57 UW163_RS10125 phosphoribosylamine--glycine ligase
Ralstonia solanacearum IBSBF1503 0.54 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase 0.57 RALBFv3_RS03545 phosphoribosylamine--glycine ligase
Ralstonia solanacearum PSI07 0.53 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase 0.58 RPSI07_RS13680 phosphoribosylamine--glycine ligase
Ralstonia solanacearum GMI1000 0.53 RS_RS08160 dihydroorotate dehydrogenase (quinone) 0.58 RS_RS10995 phosphoribosylamine--glycine ligase
Acinetobacter radioresistens SK82 0.53 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) 0.64 MPMX26_01140 Phosphoribosylamine--glycine ligase 0.79 25
Herbaspirillum seropedicae SmR1 0.52 HSERO_RS16155 dihydroorotate dehydrogenase 0.60 HSERO_RS17755 phosphoribosylamine--glycine ligase
Cupriavidus basilensis FW507-4G11 0.51 RR42_RS07465 dihydroorotate dehydrogenase 0.56 RR42_RS04730 phosphoribosylamine--glycine ligase
Acidovorax sp. GW101-3H11 0.51 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.58 Ac3H11_2421 Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Castellaniella sp019104865 MT123 0.50 ABCV34_RS07790 quinone-dependent dihydroorotate dehydrogenase 0.57 ABCV34_RS02550 phosphoribosylamine--glycine ligase
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS07450 quinone-dependent dihydroorotate dehydrogenase 0.64 ABZR86_RS13850 phosphoribosylamine--glycine ligase
Rhodanobacter denitrificans MT42 0.50 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase 0.63 LRK55_RS09805 phosphoribosylamine--glycine ligase
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase 0.63 LRK54_RS10165 phosphoribosylamine--glycine ligase
Variovorax sp. SCN45 0.49 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) 0.56 GFF302 Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Rhodanobacter sp. FW510-T8 0.48 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase 0.62 OKGIIK_13750 purD phosphoribosylamine--glycine ligase
Variovorax sp. OAS795 0.48 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase 0.56 ABID97_RS16735 phosphoribosylamine--glycine ligase
Hydrogenophaga sp. GW460-11-11-14-LB1 0.47 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.57 GFF4524 Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Marinobacter adhaerens HP15 0.47 HP15_1377 dihydroorotate dehydrogenase 0.75 HP15_3228 phosphoribosylamine-glycine ligase
Xanthomonas campestris pv. campestris strain 8004 0.47 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.66 Xcc-8004.657.1 Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Lysobacter sp. OAE881 0.45 ABIE51_RS13725 quinone-dependent dihydroorotate dehydrogenase 0.63 ABIE51_RS17770 phosphoribosylamine--glycine ligase
Pedobacter sp. GW460-11-11-14-LB5 0.43 CA265_RS14005 dihydroorotate dehydrogenase (quinone) 0.39 CA265_RS22605 phosphoribosylamine--glycine ligase
Echinicola vietnamensis KMM 6221, DSM 17526 0.42 Echvi_1806 dihydroorotate dehydrogenase, subfamily 2 0.44 Echvi_0167 phosphoribosylamine--glycine ligase
Mucilaginibacter yixingensis YX-36 DSM 26809 0.41 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase 0.43 ABZR88_RS01620 phosphoribosylamine--glycine ligase
Pontibacter actiniarum KMM 6156, DSM 19842 0.41 CA264_00865 dihydroorotate dehydrogenase (quinone) 0.42 CA264_20115 phosphoribosylamine--glycine ligase low > 74
Sinorhizobium meliloti 1021 0.40 SMc02245 dihydroorotate dehydrogenase 2 0.52 SMc00993 phosphoribosylamine--glycine ligase 0.91 9
Agrobacterium fabrum C58 0.40 Atu0486 dihydroorotate dehydrogenase 0.54 Atu0647 phosphoribosylamine--glycine ligase 0.89 8
Sphingomonas koreensis DSMZ 15582 0.39 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) 0.44 Ga0059261_1441 phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Rhizobium sp. OAE497 0.38 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase 0.54 ABIE40_RS05430 phosphoribosylamine--glycine ligase
Brevundimonas sp. GW460-12-10-14-LB2 0.38 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase 0.43 A4249_RS09255 phosphoribosylamine--glycine ligase
Rhodopseudomonas palustris CGA009 0.37 TX73_004110 quinone-dependent dihydroorotate dehydrogenase 0.53 TX73_005965 phosphoribosylamine--glycine ligase
Azospirillum sp. SherDot2 0.37 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) 0.53 MPMX19_01630 Phosphoribosylamine--glycine ligase
Azospirillum brasilense Sp245 0.36 AZOBR_RS13520 dihydroorotate dehydrogenase 0.53 AZOBR_RS04470 phosphoribosylamine--glycine ligase
Magnetospirillum magneticum AMB-1 0.36 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase 0.53 AMB_RS01075 phosphoribosylamine--glycine ligase
Rhodospirillum rubrum S1H 0.36 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) 0.48 Rru_A0646 Phosphoribosylamine--glycine ligase (NCBI)
Mycobacterium tuberculosis H37Rv 0.36 Rv2139 Probable dihydroorotate dehydrogenase PyrD 0.34 Rv0772 Probable phosphoribosylamine--glycine ligase PurD (GARS) (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase) (5'-phosphoribosylglycinamide synthetase)
Phaeobacter inhibens DSM 17395 0.33 PGA1_c12150 dihydroorotate dehydrogenase PyrD 0.47 PGA1_c23610 phosphoribosylamine--glycine ligase PurD 0.83 26
Bosea sp. OAE506 0.33 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase 0.49 ABIE41_RS23160 phosphoribosylamine--glycine ligase 0.51 65
Dinoroseobacter shibae DFL-12 0.32 Dshi_0847 Dihydroorotate oxidase (RefSeq) 0.45 Dshi_2728 phosphoribosylamine--glycine ligase (RefSeq) 0.82 7
Caulobacter crescentus NA1000 Δfur 0.31 CCNA_00562 dihydroorotate dehydrogenase 0.43 CCNA_00299 phosphoribosylamine--glycine ligase low > 67
Caulobacter crescentus NA1000 0.31 CCNA_00562 dihydroorotate dehydrogenase 0.43 CCNA_00299 phosphoribosylamine--glycine ligase 0.87 30
Bacteroides thetaiotaomicron VPI-5482 0.26 BT1009 dihydroorotate dehydrogenase (NCBI ptt file) 0.43 BT3253 phosphoribosylamine--glycine ligase (NCBI ptt file) low > 81
Bifidobacterium breve UCC2003 0.22 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase 0.42 BBR_RS13370 phosphoribosylamine--glycine ligase low > 34

Not shown: 0 genomes with orthologs for b0945 only; 11 genomes with orthologs for b4005 only