Conservation of cofitness between b2954 and b3813 in Escherichia coli BW25113

90 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b2954 yggV putative deoxyribonucleotide triphosphate pyrophosphatase (NCBI) 1.0 b3813 uvrD DNA-dependent ATPase I and helicase II (NCBI) 0.39 9
Escherichia fergusonii Becca 0.99 EFB2_00948 dITP/XTP pyrophosphatase 1.00 EFB2_04824 DNA helicase II low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS16430 XTP/dITP diphosphatase 1.00 ECOLIN_RS21885 DNA helicase II 0.76 33
Escherichia coli ECRC62 0.98 BNILDI_09690 rdgB XTP/dITP diphosphatase 1.00 BNILDI_04995 uvrD DNA helicase II
Escherichia coli HS(pFamp)R (ATCC 700891) 0.98 OHPLBJKB_00762 dITP/XTP pyrophosphatase 1.00 OHPLBJKB_04237 DNA helicase II 0.44 33
Escherichia coli ECOR27 0.98 NOLOHH_11110 rdgB XTP/dITP diphosphatase 1.00 NOLOHH_06540 uvrD DNA helicase II low > 57
Escherichia coli ECRC99 0.98 KEDOAH_08900 rdgB XTP/dITP diphosphatase 1.00 KEDOAH_13740 uvrD DNA helicase II
Escherichia coli ECRC102 0.98 NIAGMN_17005 rdgB XTP/dITP diphosphatase 1.00 NIAGMN_12165 uvrD DNA helicase II
Escherichia coli ECRC101 0.98 OKFHMN_19240 rdgB XTP/dITP diphosphatase 1.00 OKFHMN_14410 uvrD DNA helicase II
Escherichia coli ECRC98 0.98 JDDGAC_22870 rdgB XTP/dITP diphosphatase 1.00 JDDGAC_18035 uvrD DNA helicase II
Escherichia coli BL21 0.98 ECD_02784 dITP/XTP pyrophosphatase 1.00 ECD_03689 DNA-dependent ATPase I and helicase II
Escherichia coli ECOR38 0.98 HEPCGN_18545 rdgB XTP/dITP diphosphatase 1.00 HEPCGN_13115 uvrD DNA helicase II low > 85
Escherichia coli ECRC101 0.98 MCAODC_09760 rdgB XTP/dITP diphosphatase 1.00 MCAODC_04915 uvrD DNA helicase II
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF3057 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.99 GFF241 ATP-dependent DNA helicase UvrD/PcrA low > 78
Enterobacter sp. TBS_079 0.91 MPMX20_03812 dITP/XTP pyrophosphatase 0.97 MPMX20_04463 DNA helicase II 0.29 42
Klebsiella michiganensis M5al 0.90 BWI76_RS24115 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.98 BWI76_RS01220 DNA-dependent helicase II 0.29 17
Enterobacter asburiae PDN3 0.90 EX28DRAFT_2992 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.97 EX28DRAFT_4482 ATP-dependent DNA helicase UvrD (EC 3.6.1.-) low > 76
Dickeya dianthicola 67-19 0.84 HGI48_RS17365 XTP/dITP diphosphatase 0.89 HGI48_RS20035 DNA helicase II low > 71
Dickeya dianthicola ME23 0.83 DZA65_RS18455 XTP/dITP diphosphatase 0.89 DZA65_RS21080 DNA helicase II low > 75
Dickeya dadantii 3937 0.83 DDA3937_RS17320 XTP/dITP diphosphatase 0.89 DDA3937_RS19880 DNA helicase II 0.57 16
Pantoea sp. MT58 0.82 IAI47_03585 XTP/dITP diphosphatase 0.89 IAI47_18390 DNA helicase II low > 76
Rahnella sp. WP5 0.82 EX31_RS02705 XTP/dITP diphosphatase 0.87 EX31_RS15175 DNA helicase II 0.33 54
Serratia liquefaciens MT49 0.79 IAI46_21430 XTP/dITP diphosphatase 0.89 IAI46_00735 DNA helicase II low > 86
Pectobacterium carotovorum WPP14 0.78 HER17_RS03790 XTP/dITP diphosphatase 0.91 HER17_RS01360 DNA helicase II low > 75
Erwinia tracheiphila SCR3 0.77 LU632_RS05450 XTP/dITP diphosphatase 0.90 LU632_RS24125 uvrD DNA helicase II
Vibrio cholerae E7946 ATCC 55056 0.68 CSW01_02430 non-canonical purine NTP pyrophosphatase 0.71 CSW01_01015 DNA helicase II low > 62
Marinobacter adhaerens HP15 0.66 HP15_281 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.59 HP15_3403 UvrD/REP helicase low > 73
Alteromonas macleodii MIT1002 0.63 MIT1002_00940 dITP/XTP pyrophosphatase 0.67 MIT1002_00153 DNA helicase II low > 70
Kangiella aquimarina DSM 16071 0.59 B158DRAFT_0200 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.61 B158DRAFT_0238 Superfamily I DNA and RNA helicases low > 40
Shewanella loihica PV-4 0.58 Shew_1132 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase (RefSeq) 0.72 Shew_3385 uvrD DNA-dependent helicase II (RefSeq)
Xanthomonas campestris pv. campestris strain 8004 0.58 Xcc-8004.1223.1 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.57 Xcc-8004.5114.1 ATP-dependent DNA helicase UvrD/PcrA low > 74
Shewanella amazonensis SB2B 0.56 Sama_2482 Ham1-like protein (RefSeq) 0.71 Sama_0419 uvrD DNA-dependent helicase II (RefSeq) 0.51 3
Shewanella sp. ANA-3 0.56 Shewana3_1189 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase (RefSeq) 0.72 Shewana3_0469 uvrD DNA-dependent helicase II (RefSeq) low > 73
Lysobacter sp. OAE881 0.55 ABIE51_RS17295 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.59 ABIE51_RS01985 DNA helicase II low > 62
Shewanella oneidensis MR-1 0.55 SO3358 HAM1 protein (NCBI ptt file) 0.72 SO0467 uvrD DNA helicase II (NCBI ptt file) low > 76
Herbaspirillum seropedicae SmR1 0.54 HSERO_RS10660 nucleoside-triphosphate diphosphatase 0.43 HSERO_RS02160 DNA-dependent helicase low > 78
Ralstonia solanacearum UW163 0.52 UW163_RS10370 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.41 UW163_RS09895 DNA-dependent helicase
Ralstonia solanacearum IBSBF1503 0.52 RALBFv3_RS03350 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.41 RALBFv3_RS03775 DNA-dependent helicase
Dechlorosoma suillum PS 0.52 Dsui_0492 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family 0.45 Dsui_1227 DNA/RNA helicase, superfamily I low > 51
Ralstonia sp. UNC404CL21Col 0.51 ABZR87_RS15260 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.42 ABZR87_RS15705 UvrD-helicase domain-containing protein low > 80
Ralstonia solanacearum PSI07 0.51 RPSI07_RS13835 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.41 RPSI07_RS13455 DNA-dependent helicase
Ralstonia solanacearum GMI1000 0.51 RS_RS10835 non-canonical purine NTP pyrophosphatase 0.42 RS_RS11220 DNA-dependent helicase low > 80
Dyella japonica UNC79MFTsu3.2 0.51 ABZR86_RS11905 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.59 ABZR86_RS16965 DNA helicase II low > 74
Pseudomonas syringae pv. syringae B728a 0.50 Psyr_0472 Ham1-like protein 0.61 Psyr_5065 ATP-dependent DNA helicase UvrD low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.50 Psyr_0472 Ham1-like protein 0.61 Psyr_5065 ATP-dependent DNA helicase UvrD low > 86
Rhodanobacter sp. FW510-T8 0.50 OKGIIK_12155 rdgB RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.60 OKGIIK_16775 DNA helicase low > 52
Pseudomonas sp. S08-1 0.49 OH686_11015 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.60 OH686_13045 ATP-dependent DNA helicase UvrD/PcrA low > 80
Cupriavidus basilensis FW507-4G11 0.49 RR42_RS04885 nucleoside-triphosphate diphosphatase 0.42 RR42_RS15090 DNA helicase 0.32 107
Paraburkholderia bryophila 376MFSha3.1 0.49 H281DRAFT_04009 XTP/dITP diphosphohydrolase 0.44 H281DRAFT_04469 ATP-dependent DNA helicase UvrD
Rhodanobacter denitrificans MT42 0.49 LRK55_RS11465 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.59 LRK55_RS06595 DNA helicase II
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS11740 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.59 LRK54_RS06850 DNA helicase II low > 59
Pseudomonas putida KT2440 0.49 PP_5100 dITP/XTP pyrophosphatase 0.62 PP_5352 DNA-dependent ATPase I and helicase II, nucleotide Excision Repair Complex low > 96
Paraburkholderia graminis OAS925 0.49 ABIE53_003235 XTP/dITP diphosphohydrolase 0.44 ABIE53_002936 DNA helicase-2/ATP-dependent DNA helicase PcrA
Paraburkholderia sabiae LMG 24235 0.49 QEN71_RS03640 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.43 QEN71_RS05110 3'-5' exonuclease
Pseudomonas fluorescens FW300-N2E3 0.49 AO353_08195 non-canonical purine NTP pyrophosphatase 0.62 AO353_10055 DNA helicase II low > 101
Pseudomonas fluorescens SBW25 0.49 PFLU_RS28400 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.62 PFLU_RS29900 DNA helicase II low > 109
Pseudomonas fluorescens SBW25-INTG 0.49 PFLU_RS28400 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.62 PFLU_RS29900 DNA helicase II 0.15 52
Pseudomonas sp. RS175 0.49 PFR28_04248 dITP/XTP pyrophosphatase 0.62 PFR28_04523 DNA helicase II low > 88
Pseudomonas fluorescens GW456-L13 0.48 PfGW456L13_1004 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.62 PfGW456L13_724 ATP-dependent DNA helicase UvrD/PcrA low > 87
Pseudomonas fluorescens FW300-N2E2 0.48 Pf6N2E2_4594 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.62 Pf6N2E2_4273 ATP-dependent DNA helicase UvrD/PcrA low > 103
Pseudomonas fluorescens FW300-N2C3 0.48 AO356_13395 non-canonical purine NTP pyrophosphatase 0.62 AO356_11990 DNA helicase II low > 104
Pseudomonas fluorescens FW300-N1B4 0.48 Pf1N1B4_2335 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.61 Pf1N1B4_2005 ATP-dependent DNA helicase UvrD/PcrA low > 87
Pseudomonas stutzeri RCH2 0.48 Psest_0277 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family 0.61 Psest_4098 Superfamily I DNA and RNA helicases low > 67
Burkholderia phytofirmans PsJN 0.47 BPHYT_RS15330 nucleoside-triphosphate diphosphatase 0.44 BPHYT_RS13840 DNA-dependent helicase
Castellaniella sp019104865 MT123 0.46 ABCV34_RS03520 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.41 ABCV34_RS05210 UvrD-helicase domain-containing protein low > 48
Hydrogenophaga sp. GW460-11-11-14-LB1 0.44 GFF3255 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.41 GFF5598 ATP-dependent DNA helicase UvrD/PcrA
Variovorax sp. SCN45 0.42 GFF2382 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.66) 0.41 GFF4000 ATP-dependent DNA helicase UvrD/PcrA (EC 3.6.4.12) low > 127
Acidovorax sp. GW101-3H11 0.42 Ac3H11_3671 Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.15) 0.42 Ac3H11_1660 ATP-dependent DNA helicase UvrD/PcrA low > 79
Variovorax sp. OAS795 0.41 ABID97_RS23635 non-canonical purine NTP pyrophosphatase 0.42 ABID97_RS09150 UvrD-helicase domain-containing protein low > 91
Desulfovibrio vulgaris Hildenborough JW710 0.40 DVU3154 HAM1 family protein (TIGR) 0.21 DVU0156 pcrA ATP-dependent DNA helicase, UvrD/REP family (TIGR)
Rhodospirillum rubrum S1H 0.35 Rru_A3640 Ham1-like protein (NCBI) 0.34 Rru_A1536 UvrD/REP helicase (NCBI) low > 58
Synechococcus elongatus PCC 7942 0.35 Synpcc7942_1266 rdgB Ham1-like protein 0.29 Synpcc7942_2168 pcrA ATP-dependent DNA helicase, Rep family low > 38
Magnetospirillum magneticum AMB-1 0.35 AMB_RS22765 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.35 AMB_RS03725 DNA helicase II low > 64
Mycobacterium tuberculosis H37Rv 0.34 Rv1341 Conserved protein 0.32 Rv0949 Probable ATP-dependent DNA helicase II UvrD1
Mucilaginibacter yixingensis YX-36 DSM 26809 0.33 ABZR88_RS21980 non-canonical purine NTP diphosphatase 0.31 ABZR88_RS07840 ATP-dependent helicase
Sphingomonas koreensis DSMZ 15582 0.33 Ga0059261_2742 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.35 Ga0059261_0249 Superfamily I DNA and RNA helicases low > 68
Echinicola vietnamensis KMM 6221, DSM 17526 0.32 Echvi_1180 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family 0.34 Echvi_0292 Superfamily I DNA and RNA helicases
Bacteroides stercoris CC31F 0.30 HMPREF1181_RS01925 non-canonical purine NTP diphosphatase 0.31 HMPREF1181_RS16505 UvrD-helicase domain-containing protein low > 56
Bosea sp. OAE506 0.30 ABIE41_RS03300 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.37 ABIE41_RS12730 UvrD-helicase domain-containing protein low > 77
Phocaeicola dorei CL03T12C01 0.30 ABI39_RS05750 non-canonical purine NTP diphosphatase 0.31 ABI39_RS17735 UvrD-helicase domain-containing protein
Phocaeicola vulgatus CL09T03C04 0.29 HMPREF1058_RS11235 non-canonical purine NTP diphosphatase 0.31 HMPREF1058_RS03305 UvrD-helicase domain-containing protein low > 67
Phaeobacter inhibens DSM 17395 0.29 PGA1_c35040 nucleoside-triphosphatase RdgB 0.35 PGA1_c09450 DNA helicase II UvrD low > 62
Brevundimonas sp. GW460-12-10-14-LB2 0.28 A4249_RS12440 RdgB/HAM1 family non-canonical purine NTP pyrophosphatase 0.35 A4249_RS04960 UvrD-helicase domain-containing protein
Dinoroseobacter shibae DFL-12 0.28 Dshi_3462 Ham1 family protein (RefSeq) 0.35 Dshi_2483 UvrD/REP helicase (RefSeq)
Bacteroides ovatus ATCC 8483 0.28 BACOVA_02837 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 0.31 BACOVA_02365 UvrD/REP helicase
Parabacteroides merdae CL09T00C40 0.28 HMPREF1078_RS06565 non-canonical purine NTP diphosphatase 0.32 HMPREF1078_RS03560 3'-5' exonuclease low > 61
Pontibacter actiniarum KMM 6156, DSM 19842 0.27 CA264_19890 non-canonical purine NTP pyrophosphatase 0.32 CA264_07795 ATP-dependent DNA helicase
Bacteroides thetaiotaomicron VPI-5482 0.27 BT3128 putative xanthosine triphosphate pyrophosphatase (NCBI ptt file) 0.31 BT0657 ATP-dependent DNA helicase (NCBI ptt file)
Pedobacter sp. GW460-11-11-14-LB5 0.27 CA265_RS24990 non-canonical purine NTP pyrophosphatase 0.31 CA265_RS12980 ATP-dependent DNA helicase
Azospirillum brasilense Sp245 0.25 AZOBR_RS02200 nucleoside-triphosphate diphosphatase 0.36 AZOBR_RS12445 DNA helicase II low > 97
Azospirillum sp. SherDot2 0.24 MPMX19_02575 dITP/XTP pyrophosphatase 0.36 MPMX19_01610 ATP-dependent DNA helicase PcrA low > 112

Not shown: 12 genomes with orthologs for b2954 only; 1 genomes with orthologs for b3813 only