| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BW25113 | 1.0 | b0945 | pyrD | dihydroorotate dehydrogenase (NCBI) | 1.0 | b2023 | hisH | imidazole glycerol phosphate synthase subunit HisH (NCBI) | 0.83 | 15 |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_03015 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 1.00 | NIAGMN_22445 | hisH | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_02721 | | Dihydroorotate dehydrogenase (quinone) | 1.00 | OHPLBJKB_01677 | | Imidazole glycerol phosphate synthase subunit HisH | low | > 73 |
| Escherichia coli ECRC62 | 1.00 | BNILDI_20015 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 1.00 | BNILDI_14725 | hisH | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Escherichia coli ECRC101 | 1.00 | OKFHMN_05295 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 1.00 | OKFHMN_24500 | hisH | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Escherichia coli BL21 | 1.00 | ECD_00949 | | dihydro-orotate oxidase, FMN-linked | 1.00 | ECD_01925 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | low | > 60 |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_22440 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 1.00 | KEDOAH_03650 | hisH | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_08905 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 1.00 | JDDGAC_28610 | hisH | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Escherichia coli ECOR27 | 1.00 | NOLOHH_21850 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 1.00 | NOLOHH_15815 | hisH | imidazole glycerol phosphate synthase subunit HisH | low | > 57 |
| Escherichia coli ECRC101 | 1.00 | MCAODC_24685 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 1.00 | MCAODC_20440 | hisH | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Escherichia coli ECOR38 | 1.00 | HEPCGN_23225 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 1.00 | HEPCGN_03205 | hisH | imidazole glycerol phosphate synthase subunit HisH | low | > 85 |
| Escherichia coli Nissle 1917 | 0.99 | ECOLIN_RS04965 | | quinone-dependent dihydroorotate dehydrogenase | 1.00 | ECOLIN_RS11960 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Escherichia fergusonii Becca | 0.99 | EFB2_03126 | | Dihydroorotate dehydrogenase (quinone) | 1.00 | EFB2_01833 | | Imidazole glycerol phosphate synthase subunit HisH | low | > 86 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.96 | GFF3236 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.93 | GFF3909 | | Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) | low | > 78 |
| Enterobacter sp. TBS_079 | 0.94 | MPMX20_01596 | | Dihydroorotate dehydrogenase (quinone) | 0.92 | MPMX20_03005 | | Imidazole glycerol phosphate synthase subunit HisH | 0.76 | 50 |
| Enterobacter asburiae PDN3 | 0.94 | EX28DRAFT_1998 | | dihydroorotate oxidase A (EC 1.3.3.1) | 0.92 | EX28DRAFT_0536 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | — | — |
| Klebsiella michiganensis M5al | 0.93 | BWI76_RS09910 | | dihydroorotate dehydrogenase (quinone) | 0.89 | BWI76_RS18940 | | imidazole glycerol phosphate synthase subunit HisH | 0.58 | 52 |
| Serratia liquefaciens MT49 | 0.87 | IAI46_08805 | | quinone-dependent dihydroorotate dehydrogenase | 0.82 | IAI46_08195 | | imidazole glycerol phosphate synthase subunit HisH | low | > 86 |
| Pectobacterium carotovorum WPP14 | 0.86 | HER17_RS12005 | | quinone-dependent dihydroorotate dehydrogenase | 0.75 | HER17_RS12245 | | imidazole glycerol phosphate synthase subunit HisH | 0.95 | 22 |
| Dickeya dianthicola ME23 | 0.86 | DZA65_RS13390 | | quinone-dependent dihydroorotate dehydrogenase | 0.77 | DZA65_RS10040 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Rahnella sp. WP5 | 0.86 | EX31_RS18095 | | quinone-dependent dihydroorotate dehydrogenase | 0.75 | EX31_RS11455 | | imidazole glycerol phosphate synthase subunit HisH | 0.94 | 10 |
| Dickeya dadantii 3937 | 0.86 | DDA3937_RS12855 | | quinone-dependent dihydroorotate dehydrogenase | 0.78 | DDA3937_RS09720 | | imidazole glycerol phosphate synthase subunit HisH | 0.53 | 72 |
| Dickeya dianthicola 67-19 | 0.85 | HGI48_RS12925 | | quinone-dependent dihydroorotate dehydrogenase | 0.77 | HGI48_RS09730 | | imidazole glycerol phosphate synthase subunit HisH | low | > 71 |
| Erwinia tracheiphila SCR3 | 0.84 | LU632_RS09955 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 0.76 | LU632_RS08930 | hisH | imidazole glycerol phosphate synthase subunit HisH | 0.87 | 13 |
| Pantoea sp. MT58 | 0.81 | IAI47_12705 | | quinone-dependent dihydroorotate dehydrogenase | 0.78 | IAI47_07075 | | imidazole glycerol phosphate synthase subunit HisH | 0.80 | 22 |
| Vibrio cholerae E7946 ATCC 55056 | 0.72 | CSW01_07490 | | dihydroorotate dehydrogenase (quinone) | 0.62 | CSW01_05765 | | imidazole glycerol phosphate synthase subunit HisH | low | > 62 |
| Shewanella sp. ANA-3 | 0.63 | Shewana3_1786 | | dihydroorotate dehydrogenase 2 (RefSeq) | 0.49 | Shewana3_1850 | hisH | imidazole glycerol phosphate synthase subunit HisH (RefSeq) | 0.87 | 22 |
| Shewanella loihica PV-4 | 0.63 | Shew_1810 | | dihydroorotate dehydrogenase 2 (RefSeq) | 0.53 | Shew_2201 | hisH | imidazole glycerol phosphate synthase subunit HisH (RefSeq) | 0.73 | 47 |
| Shewanella amazonensis SB2B | 0.62 | Sama_1593 | | dihydroorotate dehydrogenase 2 (RefSeq) | 0.46 | Sama_1945 | hisH | imidazole glycerol phosphate synthase subunit HisH (RefSeq) | 0.61 | 57 |
| Shewanella oneidensis MR-1 | 0.62 | SO2592 | pyrD | dihydroorotate dehydrogenase (NCBI ptt file) | 0.49 | SO2070 | hisH | amidotransferase HisH (NCBI ptt file) | 0.83 | 49 |
| Alteromonas macleodii MIT1002 | 0.58 | MIT1002_02035 | | Dihydroorotate dehydrogenase (quinone) | 0.51 | MIT1002_02636 | | Imidazole glycerol phosphate synthase subunit HisH | low | > 70 |
| Pseudomonas fluorescens SBW25 | 0.57 | PFLU_RS22550 | | quinone-dependent dihydroorotate dehydrogenase | 0.30 | PFLU_RS01610 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.57 | PFLU_RS22550 | | quinone-dependent dihydroorotate dehydrogenase | 0.30 | PFLU_RS01610 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.57 | QEN71_RS22765 | | quinone-dependent dihydroorotate dehydrogenase | 0.30 | QEN71_RS27845 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.57 | Pf1N1B4_3842 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.31 | Pf1N1B4_1626 | | Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.57 | AO353_00780 | | dihydroorotate dehydrogenase (quinone) | 0.31 | AO353_12075 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Burkholderia phytofirmans PsJN | 0.57 | BPHYT_RS08565 | | dihydroorotate dehydrogenase | 0.29 | BPHYT_RS17690 | | imidazole glycerol phosphate synthase | 0.49 | 94 |
| Pseudomonas simiae WCS417 | 0.57 | PS417_20935 | | dihydroorotate dehydrogenase | 0.30 | PS417_01565 | | imidazole glycerol phosphate synthase | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.57 | Psyr_2106 | | dihydroorotate oxidase A | 0.30 | Psyr_4896 | | imidazole glycerol phosphate synthase subunit hisH | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.57 | Psyr_2106 | | dihydroorotate oxidase A | 0.30 | Psyr_4896 | | imidazole glycerol phosphate synthase subunit hisH | — | — |
| Paraburkholderia graminis OAS925 | 0.56 | ABIE53_001954 | | dihydroorotate dehydrogenase | 0.29 | ABIE53_003697 | | glutamine amidotransferase | — | — |
| Pseudomonas sp. RS175 | 0.56 | PFR28_01054 | | Dihydroorotate dehydrogenase (quinone) | 0.31 | PFR28_04930 | | Imidazole glycerol phosphate synthase subunit HisH | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.56 | Pf6N2E2_2347 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.31 | Pf6N2E2_3841 | | Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.56 | PfGW456L13_4095 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.30 | PfGW456L13_361 | | Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.56 | AO356_02610 | | dihydroorotate dehydrogenase (quinone) | 0.36 | AO356_03385 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Pseudomonas sp. S08-1 | 0.55 | OH686_03120 | | dihydroorotate dehydrogenase (fumarate) | 0.31 | OH686_14580 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | — | — |
| Dechlorosoma suillum PS | 0.55 | Dsui_2978 | | dihydroorotate dehydrogenase, subfamily 2 | 0.30 | Dsui_1416 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | — | — |
| Kangiella aquimarina DSM 16071 | 0.55 | B158DRAFT_2228 | | dihydroorotate oxidase A (EC 1.3.3.1) | 0.24 | B158DRAFT_2290 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | — | — |
| Pseudomonas stutzeri RCH2 | 0.55 | Psest_1947 | | dihydroorotate dehydrogenase, subfamily 2 | 0.31 | Psest_0153 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | 0.45 | 18 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.55 | H281DRAFT_00743 | | dihydroorotate oxidase A | 0.29 | H281DRAFT_05657 | | imidazole glycerol phosphate synthase subunit hisH | — | — |
| Ralstonia sp. UNC404CL21Col | 0.54 | ABZR87_RS13360 | | quinone-dependent dihydroorotate dehydrogenase | 0.30 | ABZR87_RS02480 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Pseudomonas putida KT2440 | 0.54 | PP_2095 | | Dihydroorotate dehydrogenase (quinone) | 0.31 | PP_0290 | | Imidazole glycerol phosphate synthase subunit HisH | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.54 | RALBFv3_RS01570 | | quinone-dependent dihydroorotate dehydrogenase | 0.30 | RALBFv3_RS06825 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Ralstonia solanacearum UW163 | 0.54 | UW163_RS14880 | | quinone-dependent dihydroorotate dehydrogenase | 0.30 | UW163_RS06790 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Ralstonia solanacearum GMI1000 | 0.53 | RS_RS08160 | | dihydroorotate dehydrogenase (quinone) | 0.31 | RS_RS14770 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Ralstonia solanacearum PSI07 | 0.53 | RPSI07_RS15920 | | quinone-dependent dihydroorotate dehydrogenase | 0.31 | RPSI07_RS10410 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Acinetobacter radioresistens SK82 | 0.53 | MPMX26_01120 | | Dihydroorotate dehydrogenase (quinone) | 0.37 | MPMX26_02846 | | Imidazole glycerol phosphate synthase subunit HisH | low | > 36 |
| Herbaspirillum seropedicae SmR1 | 0.52 | HSERO_RS16155 | | dihydroorotate dehydrogenase | 0.33 | HSERO_RS21015 | | imidazole glycerol phosphate synthase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.51 | RR42_RS07465 | | dihydroorotate dehydrogenase | 0.28 | RR42_RS18895 | | imidazole glycerol phosphate synthase | — | — |
| Acidovorax sp. GW101-3H11 | 0.51 | Ac3H11_4100 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.30 | Ac3H11_4731 | | Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) | — | — |
| Castellaniella sp019104865 MT123 | 0.50 | ABCV34_RS07790 | | quinone-dependent dihydroorotate dehydrogenase | 0.25 | ABCV34_RS11240 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.50 | ABZR86_RS07450 | | quinone-dependent dihydroorotate dehydrogenase | 0.45 | ABZR86_RS06715 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Rhodanobacter denitrificans MT42 | 0.50 | LRK55_RS15740 | | quinone-dependent dihydroorotate dehydrogenase | 0.43 | LRK55_RS01370 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.49 | LRK54_RS15985 | | quinone-dependent dihydroorotate dehydrogenase | 0.43 | LRK54_RS01590 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Variovorax sp. SCN45 | 0.49 | GFF960 | | Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) | 0.33 | GFF5350 | | Imidazole glycerol phosphate synthase amidotransferase subunit HisH | — | — |
| Variovorax sp. OAS795 | 0.48 | ABID97_RS14065 | | quinone-dependent dihydroorotate dehydrogenase | 0.32 | ABID97_RS23135 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Rhodanobacter sp. FW510-T8 | 0.48 | OKGIIK_09010 | pyrD | quinone-dependent dihydroorotate dehydrogenase | 0.43 | OKGIIK_04965 | hisH | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.47 | GFF4211 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.30 | GFF1311 | | Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) | — | — |
| Marinobacter adhaerens HP15 | 0.47 | HP15_1377 | | dihydroorotate dehydrogenase | 0.33 | HP15_3011 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.47 | Xcc-8004.3032.1 | | Dihydroorotate dehydrogenase (EC 1.3.3.1) | 0.41 | Xcc-8004.2945.1 | | Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) | — | — |
| Lysobacter sp. OAE881 | 0.45 | ABIE51_RS13725 | | quinone-dependent dihydroorotate dehydrogenase | 0.40 | ABIE51_RS13310 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.43 | CA265_RS14005 | | dihydroorotate dehydrogenase (quinone) | 0.40 | CA265_RS03620 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.42 | Echvi_1806 | | dihydroorotate dehydrogenase, subfamily 2 | 0.36 | Echvi_2514 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | — | — |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.41 | ABZR88_RS12040 | | quinone-dependent dihydroorotate dehydrogenase | 0.37 | ABZR88_RS06865 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.41 | CA264_00865 | | dihydroorotate dehydrogenase (quinone) | 0.40 | CA264_05100 | | imidazole glycerol phosphate synthase subunit HisH | low | > 74 |
| Sinorhizobium meliloti 1021 | 0.40 | SMc02245 | | dihydroorotate dehydrogenase 2 | 0.30 | SMc02572 | | imidazole glycerol phosphate synthase subunit HisH | 0.78 | 70 |
| Agrobacterium fabrum C58 | 0.40 | Atu0486 | | dihydroorotate dehydrogenase | 0.31 | Atu0041 | | glutamine amidotransferase | 0.66 | 68 |
| Sphingomonas koreensis DSMZ 15582 | 0.39 | Ga0059261_1468 | | dihydroorotate oxidase A (EC 1.3.3.1) | 0.30 | Ga0059261_3124 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | — | — |
| Rhizobium sp. OAE497 | 0.38 | ABIE40_RS02420 | | quinone-dependent dihydroorotate dehydrogenase | 0.30 | ABIE40_RS19450 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.38 | A4249_RS00280 | | quinone-dependent dihydroorotate dehydrogenase | 0.40 | A4249_RS10705 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Rhodopseudomonas palustris CGA009 | 0.37 | TX73_004110 | | quinone-dependent dihydroorotate dehydrogenase | 0.29 | TX73_001615 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Azospirillum sp. SherDot2 | 0.37 | MPMX19_02083 | | Dihydroorotate dehydrogenase (quinone) | 0.32 | MPMX19_02545 | | Imidazole glycerol phosphate synthase subunit HisH | — | — |
| Azospirillum brasilense Sp245 | 0.36 | AZOBR_RS13520 | | dihydroorotate dehydrogenase | 0.29 | AZOBR_RS01670 | | imidazole glycerol phosphate synthase | 0.65 | 20 |
| Magnetospirillum magneticum AMB-1 | 0.36 | AMB_RS19685 | | quinone-dependent dihydroorotate dehydrogenase | 0.28 | AMB_RS22935 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Rhodospirillum rubrum S1H | 0.36 | Rru_A0514 | | Dihydroorotate dehydrogenase 2 (NCBI) | 0.31 | Rru_A3596 | | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (NCBI) | 0.59 | 47 |
| Mycobacterium tuberculosis H37Rv | 0.36 | Rv2139 | | Probable dihydroorotate dehydrogenase PyrD | 0.31 | Rv1602 | | Probable amidotransferase HisH | — | — |
| Bosea sp. OAE506 | 0.33 | ABIE41_RS24065 | | quinone-dependent dihydroorotate dehydrogenase | 0.32 | ABIE41_RS03955 | | imidazole glycerol phosphate synthase subunit HisH | low | > 77 |
| Phaeobacter inhibens DSM 17395 | 0.33 | PGA1_c12150 | | dihydroorotate dehydrogenase PyrD | 0.32 | PGA1_c09320 | | imidazole glycerol phosphate synthase subunit HisH | — | — |
| Dinoroseobacter shibae DFL-12 | 0.32 | Dshi_0847 | | Dihydroorotate oxidase (RefSeq) | 0.32 | Dshi_0795 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (RefSeq) | — | — |
| Caulobacter crescentus NA1000 | 0.31 | CCNA_00562 | | dihydroorotate dehydrogenase | 0.31 | CCNA_03851 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | 0.82 | 48 |
| Caulobacter crescentus NA1000 Δfur | 0.31 | CCNA_00562 | | dihydroorotate dehydrogenase | 0.31 | CCNA_03851 | | imidazole glycerol phosphate synthase, glutamine amidotransferase subunit | low | > 67 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.26 | BT1009 | | dihydroorotate dehydrogenase (NCBI ptt file) | 0.42 | BT1380 | | imidazole glycerol phosphate synthase subunit hisH (NCBI ptt file) | low | > 81 |
| Bifidobacterium breve UCC2003 | 0.22 | BBR_RS12895 | | quinone-dependent dihydroorotate dehydrogenase | 0.29 | BBR_RS17035 | | imidazole glycerol phosphate synthase subunit HisH | low | > 34 |
Not shown: 0 genomes with orthologs for b0945 only; 10 genomes with orthologs for b2023 only