Conservation of cofitness between b0774 and b0750 in Escherichia coli BW25113

87 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0774 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase (NCBI) 1.0 b0750 nadA quinolinate synthetase (NCBI) 0.40 8
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_02939 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.99 OHPLBJKB_02963 Quinolinate synthase A low > 73
Escherichia coli BL21 0.99 ECD_00741 7,8-diaminopelargonic acid synthase, PLP-dependent 1.00 ECD_00703 quinolinate synthase, subunit A low > 60
Escherichia coli ECOR27 0.99 NOLOHH_22775 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 1.00 NOLOHH_23190 nadA quinolinate synthase NadA low > 57
Escherichia coli ECRC62 0.99 BNILDI_21045 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 1.00 BNILDI_21185 nadA quinolinate synthase NadA — —
Escherichia coli ECRC99 0.99 KEDOAH_21505 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.99 KEDOAH_21205 nadA quinolinate synthase NadA — —
Escherichia coli ECRC102 0.99 NIAGMN_04450 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.99 NIAGMN_04810 nadA quinolinate synthase NadA — —
Escherichia coli ECRC101 0.99 MCAODC_25620 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.99 MCAODC_25980 nadA quinolinate synthase NadA — —
Escherichia coli ECRC101 0.99 OKFHMN_06405 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.99 OKFHMN_06760 nadA quinolinate synthase NadA — —
Escherichia coli ECOR38 0.98 HEPCGN_01635 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.99 HEPCGN_01515 nadA quinolinate synthase NadA low > 85
Escherichia coli ECRC98 0.98 JDDGAC_10040 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.99 JDDGAC_10415 nadA quinolinate synthase NadA — —
Escherichia fergusonii Becca 0.98 EFB2_03331 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.99 EFB2_03356 Quinolinate synthase A low > 86
Escherichia coli Nissle 1917 0.98 ECOLIN_RS04125 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.99 ECOLIN_RS03990 quinolinate synthase NadA low > 52
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.88 GFF670 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.90 GFF4 Quinolinate synthetase (EC 2.5.1.72) — —
Klebsiella michiganensis M5al 0.87 BWI76_RS08755 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.90 BWI76_RS08580 quinolinate synthetase 0.15 41
Enterobacter sp. TBS_079 0.86 MPMX20_01402 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.89 MPMX20_01377 Quinolinate synthase A low > 85
Enterobacter asburiae PDN3 0.85 EX28DRAFT_2217 adenosylmethionine-8-amino-7-oxononanoate transaminase 0.90 EX28DRAFT_2245 quinolinate synthetase (EC 2.5.1.72) low > 76
Serratia liquefaciens MT49 0.75 IAI46_06520 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.86 IAI46_06380 quinolinate synthase NadA low > 86
Dickeya dadantii 3937 0.75 DDA3937_RS08505 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.81 DDA3937_RS06545 quinolinate synthase NadA 0.40 59
Dickeya dianthicola 67-19 0.75 HGI48_RS08670 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.81 HGI48_RS06595 quinolinate synthase NadA 0.68 22
Dickeya dianthicola ME23 0.74 DZA65_RS08960 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.81 DZA65_RS06945 quinolinate synthase NadA 0.55 63
Pectobacterium carotovorum WPP14 0.74 HER17_RS13465 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.85 HER17_RS14820 quinolinate synthase NadA low > 75
Rahnella sp. WP5 0.73 EX31_RS23690 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.83 EX31_RS23525 quinolinate synthase NadA low > 89
Pantoea sp. MT58 0.73 IAI47_13535 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.87 IAI47_13635 quinolinate synthase NadA low > 76
Vibrio cholerae E7946 ATCC 55056 0.68 CSW01_05640 adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA 0.74 CSW01_09180 quinolinate synthase low > 62
Alteromonas macleodii MIT1002 0.63 MIT1002_01378 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.71 MIT1002_01344 Quinolinate synthase A — —
Parabacteroides merdae CL09T00C40 0.61 HMPREF1078_RS15295 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.34 HMPREF1078_RS06555 quinolinate synthase NadA — —
Phocaeicola dorei CL03T12C01 0.59 ABI39_RS14245 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.36 ABI39_RS05755 quinolinate synthase NadA — —
Phocaeicola vulgatus CL09T03C04 0.59 HMPREF1058_RS17955 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.36 HMPREF1058_RS11230 quinolinate synthase NadA — —
Acinetobacter radioresistens SK82 0.57 MPMX26_02454 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.68 MPMX26_02602 Quinolinate synthase A low > 36
Shewanella sp. ANA-3 0.56 Shewana3_2520 aminotransferase (RefSeq) 0.74 Shewana3_2128 quinolinate synthetase (RefSeq) — —
Shewanella loihica PV-4 0.56 Shew_1718 adenosylmethionine-8-amino-7-oxononanoate aminotransferase (RefSeq) 0.75 Shew_1928 quinolinate synthetase (RefSeq) — —
Shewanella oneidensis MR-1 0.55 SO2741 bioA adenosylmethionine--8-amino-7-oxononanoate aminotransferase (NCBI ptt file) 0.75 SO2342 nadA quinolinate synthetase complex, subunit A (NCBI ptt file) — —
Shewanella amazonensis SB2B 0.51 Sama_1437 adenosylmethionine-8-amino-7-oxononanoate aminotransferase (RefSeq) 0.74 Sama_1712 quinolinate synthetase (RefSeq) — —
Phaeobacter inhibens DSM 17395 0.50 PGA1_c09150 adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.22 PGA1_c27790 quinolinate synthetase A 0.36 53
Mycobacterium tuberculosis H37Rv 0.47 Rv1568 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.23 Rv1594 Probable quinolinate synthetase NadA — —
Caulobacter crescentus NA1000 Δfur 0.46 CCNA_01648 adenosylmethionine-8-amino-7-oxononanoate 0.23 CCNA_03006 quinolinate synthetase A — —
Caulobacter crescentus NA1000 0.46 CCNA_01648 adenosylmethionine-8-amino-7-oxononanoate 0.23 CCNA_03006 quinolinate synthetase A — —
Castellaniella sp019104865 MT123 0.42 ABCV34_RS15300 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.58 ABCV34_RS03700 quinolinate synthase NadA low > 48
Rhodanobacter denitrificans MT42 0.36 LRK55_RS03920 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.23 LRK55_RS13615 quinolinate synthase NadA low > 63
Rhodanobacter denitrificans FW104-10B01 0.36 LRK54_RS04150 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.23 LRK54_RS13900 quinolinate synthase NadA low > 59
Pedobacter sp. GW460-11-11-14-LB5 0.35 CA265_RS07530 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.34 CA265_RS21180 quinolinate synthase — —
Rhodanobacter sp. FW510-T8 0.35 OKGIIK_11015 bioA adenosylmethionine--8-amino-7-oxononanoate transaminase 0.21 OKGIIK_00930 nadA quinolinate synthase NadA low > 52
Desulfovibrio vulgaris Miyazaki F 0.34 DvMF_1002 adenosylmethionine-8-amino-7-oxononanoate aminotransferase (RefSeq) 0.13 DvMF_0525 quinolinate synthetase (RefSeq) — —
Pseudomonas sp. S08-1 0.34 OH686_10850 adenosylmethionine-8-amino-7-oxononanoate transaminase 0.66 OH686_19190 quinolinate synthetase complex, A subunit low > 80
Pseudomonas fluorescens FW300-N2E3 0.34 AO353_08045 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.65 AO353_03525 quinolinate synthase A 0.53 76
Pseudomonas syringae pv. syringae B728a ΔmexB 0.34 Psyr_0454 adenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme 0.64 Psyr_1542 quinolinate synthetase low > 86
Pseudomonas syringae pv. syringae B728a 0.34 Psyr_0454 adenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme 0.64 Psyr_1542 quinolinate synthetase low > 86
Pseudomonas fluorescens FW300-N2C3 0.34 AO356_13570 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.65 AO356_18145 quinolinate synthase A 0.59 6
Pseudomonas stutzeri RCH2 0.34 Psest_0306 adenosylmethionine-8-amino-7-oxononanoate transaminase 0.67 Psest_1509 quinolinate synthetase complex, A subunit 0.49 43
Pseudomonas simiae WCS417 0.34 PS417_26540 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.65 PS417_22385 quinolinate synthase A low > 88
Pseudomonas fluorescens FW300-N1B4 0.34 Pf1N1B4_2377 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.66 Pf1N1B4_626 Quinolinate synthetase (EC 2.5.1.72) 0.46 60
Pseudomonas putida KT2440 0.34 PP_4984 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.67 PP_1231 quinolinate synthase [4Fe-4S] cluster subunit 0.48 21
Kangiella aquimarina DSM 16071 0.34 B158DRAFT_0179 adenosylmethionine-8-amino-7-oxononanoate transaminase 0.69 B158DRAFT_2453 quinolinate synthetase (EC 2.5.1.72) — —
Pseudomonas fluorescens FW300-N2E2 0.34 Pf6N2E2_4631 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.66 Pf6N2E2_5553 Quinolinate synthetase (EC 2.5.1.72) 0.42 57
Pseudomonas sp. RS175 0.34 PFR28_04208 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.66 PFR28_03388 Quinolinate synthase A low > 88
Pseudomonas fluorescens GW456-L13 0.34 PfGW456L13_1044 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.66 PfGW456L13_1863 Quinolinate synthetase (EC 2.5.1.72) 0.74 39
Pseudomonas fluorescens SBW25 0.33 PFLU_RS28195 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.65 PFLU_RS24025 quinolinate synthase NadA low > 109
Azospirillum brasilense Sp245 0.33 AZOBR_RS31120 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.22 AZOBR_RS18690 quinolinate synthetase low > 97
Pseudomonas fluorescens SBW25-INTG 0.33 PFLU_RS28195 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.65 PFLU_RS24025 quinolinate synthase NadA 0.37 47
Marinobacter adhaerens HP15 0.33 HP15_2925 adenosylmethionine-8-amino-7-oxononanoate transaminase 0.68 HP15_2032 quinolinate synthetase complex, A subunit — —
Magnetospirillum magneticum AMB-1 0.32 AMB_RS13895 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.35 AMB_RS19660 quinolinate synthase NadA — —
Rhodopseudomonas palustris CGA009 0.32 TX73_015405 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.23 TX73_005425 quinolinate synthase NadA — —
Variovorax sp. SCN45 0.32 GFF145 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.59 GFF2575 Quinolinate synthetase (EC 2.5.1.72) low > 127
Synechococcus elongatus PCC 7942 0.32 Synpcc7942_0031 bioA aminotransferase 0.33 Synpcc7942_1448 nadA quinolinate synthetase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.31 GFF3993 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.60 GFF1216 Quinolinate synthetase (EC 2.5.1.72) low > 90
Desulfovibrio vulgaris Hildenborough JW710 0.30 DVU2559 bioA adenosylmethionine--8-amino-7-oxononanoate aminotransferase (TIGR) 0.13 DVU1808 nadA quinolinate synthetase complex, subunit A (TIGR) — —
Paraburkholderia graminis OAS925 0.30 ABIE53_000580 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.62 ABIE53_003294 quinolinate synthase low > 113
Agrobacterium fabrum C58 0.30 Atu4000 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.23 Atu4098 quinolinate synthetase 0.73 12
Sphingomonas koreensis DSMZ 15582 0.30 Ga0059261_3674 adenosylmethionine-8-amino-7-oxononanoate transaminase 0.36 Ga0059261_0051 quinolinate synthetase (EC 2.5.1.72) — —
Rhizobium sp. OAE497 0.30 ABIE40_RS21060 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.24 ABIE40_RS23255 quinolinate synthase NadA low > 107
Burkholderia phytofirmans PsJN 0.30 BPHYT_RS02165 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.61 BPHYT_RS15650 quinolinate synthetase 0.29 6
Paraburkholderia bryophila 376MFSha3.1 0.30 H281DRAFT_02094 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.61 H281DRAFT_04071 quinolinate synthetase low > 103
Ralstonia sp. UNC404CL21Col 0.30 ABZR87_RS12335 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.64 ABZR87_RS00355 quinolinate synthase NadA 0.61 58
Ralstonia solanacearum PSI07 0.29 RPSI07_RS16705 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.63 RPSI07_RS12650 quinolinate synthase NadA low > 81
Fusobacterium nucleatum SB010 0.29 HUW76_05105 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.27 HUW76_10740 quinolinate synthase NadA low > 35
Acidovorax sp. GW101-3H11 0.29 Ac3H11_3828 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62) 0.60 Ac3H11_3837 Quinolinate synthetase (EC 2.5.1.72) low > 79
Ralstonia solanacearum IBSBF1503 0.29 RALBFv3_RS00815 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.63 RALBFv3_RS04735 quinolinate synthase NadA low > 76
Ralstonia solanacearum UW163 0.29 UW163_RS14150 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.63 UW163_RS08935 quinolinate synthase NadA — —
Variovorax sp. OAS795 0.29 ABID97_RS16265 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.60 ABID97_RS07415 quinolinate synthase NadA low > 91
Ralstonia solanacearum GMI1000 0.29 RS_RS07430 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.63 RS_RS12295 quinolinate synthase 0.33 20
Paraburkholderia sabiae LMG 24235 0.28 QEN71_RS01100 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.62 QEN71_RS03060 quinolinate synthase NadA — —
Herbaspirillum seropedicae SmR1 0.28 HSERO_RS12250 adenosylmethionine--8-amino-7-oxononanoate aminotransferase 0.62 HSERO_RS11065 quinolinate synthetase low > 78
Cupriavidus basilensis FW507-4G11 0.27 RR42_RS00925 adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA 0.64 RR42_RS17020 quinolinate synthetase 0.64 6
Methanococcus maripaludis S2 0.25 MMP_RS04500 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.20 MMP_RS06390 quinolinate synthase NadA — —
Methanococcus maripaludis JJ 0.25 MMJJ_RS00645 adenosylmethionine--8-amino-7-oxononanoate transaminase 0.20 MMJJ_RS07960 quinolinate synthase NadA low > 28
Sinorhizobium meliloti 1021 0.21 SMc01534 omega amino acid--pyruvate transaminase 0.23 SMc02601 quinolinate synthetase low > 103
Rhodospirillum rubrum S1H 0.20 Rru_A1541 Aminotransferase class-III (NCBI) 0.23 Rru_A1434 Quinolinate synthetase A (NCBI) low > 58

Not shown: 8 genomes with orthologs for b0774 only; 6 genomes with orthologs for b0750 only