Conservation of cofitness between b0109 and b0242 in Escherichia coli BW25113

93 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b0109 nadC nicotinate-nucleotide pyrophosphorylase (NCBI) 1.0 b0242 proB gamma-glutamyl kinase (NCBI) 0.65 19
Escherichia coli ECOR27 1.00 NOLOHH_02875 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 NOLOHH_02050 proB Glutamate 5-kinase low > 57
Escherichia coli BL21 1.00 ECD_00108 quinolinate phosphoribosyltransferase 1.00 ECD_00239 gamma-glutamate kinase low > 60
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03552 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 1.00 OHPLBJKB_03398 Glutamate 5-kinase low > 73
Escherichia coli ECRC102 1.00 NIAGMN_08380 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 NIAGMN_07535 proB Glutamate 5-kinase — —
Escherichia coli ECRC62 1.00 BNILDI_08735 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 BNILDI_00245 proB Glutamate 5-kinase — —
Escherichia coli ECRC101 1.00 MCAODC_01045 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 MCAODC_00195 proB Glutamate 5-kinase — —
Escherichia fergusonii Becca 1.00 EFB2_03940 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 1.00 EFB2_03778 Glutamate 5-kinase low > 86
Escherichia coli ECRC101 1.00 OKFHMN_10530 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 OKFHMN_09675 proB Glutamate 5-kinase — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS00585 carboxylating nicotinate-nucleotide diphosphorylase 1.00 ECOLIN_RS01825 glutamate 5-kinase low > 52
Escherichia coli ECRC99 1.00 KEDOAH_17625 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 KEDOAH_18480 proB Glutamate 5-kinase — —
Escherichia coli ECRC98 1.00 JDDGAC_14125 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 JDDGAC_13300 proB Glutamate 5-kinase — —
Escherichia coli ECOR38 0.99 HEPCGN_08510 nadC carboxylating nicotinate-nucleotide diphosphorylase 1.00 HEPCGN_07780 proB Glutamate 5-kinase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.87 GFF130 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.98 GFF4114 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA low > 78
Klebsiella michiganensis M5al 0.81 BWI76_RS04845 nicotinate-nucleotide pyrophosphorylase 0.95 BWI76_RS05840 glutamate 5-kinase low > 92
Enterobacter sp. TBS_079 0.81 MPMX20_00800 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.96 MPMX20_00927 Glutamate 5-kinase 0.34 50
Enterobacter asburiae PDN3 0.81 EX28DRAFT_3702 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.96 EX28DRAFT_2651 glutamate 5-kinase low > 76
Rahnella sp. WP5 0.74 EX31_RS03515 carboxylating nicotinate-nucleotide diphosphorylase 0.89 EX31_RS20980 glutamate 5-kinase 0.55 44
Serratia liquefaciens MT49 0.71 IAI46_03530 carboxylating nicotinate-nucleotide diphosphorylase 0.89 IAI46_04430 glutamate 5-kinase low > 86
Erwinia tracheiphila SCR3 0.70 LU632_RS03040 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.88 LU632_RS01185 proB glutamate 5-kinase low > 74
Pectobacterium carotovorum WPP14 0.69 HER17_RS03250 carboxylating nicotinate-nucleotide diphosphorylase 0.84 HER17_RS04700 glutamate 5-kinase low > 75
Pantoea sp. MT58 0.69 IAI47_15845 carboxylating nicotinate-nucleotide diphosphorylase 0.89 IAI47_15120 glutamate 5-kinase 0.54 13
Dickeya dadantii 3937 0.67 DDA3937_RS17955 carboxylating nicotinate-nucleotide diphosphorylase 0.82 DDA3937_RS16535 glutamate 5-kinase low > 74
Dickeya dianthicola ME23 0.66 DZA65_RS19035 carboxylating nicotinate-nucleotide diphosphorylase 0.82 DZA65_RS17695 glutamate 5-kinase low > 75
Dickeya dianthicola 67-19 0.66 HGI48_RS17890 carboxylating nicotinate-nucleotide diphosphorylase 0.83 HGI48_RS16605 glutamate 5-kinase low > 71
Shewanella amazonensis SB2B 0.58 Sama_0371 nicotinate-nucleotide diphosphorylase (carboxylating) (RefSeq) 0.60 Sama_2516 gamma-glutamyl kinase (RefSeq) — —
Vibrio cholerae E7946 ATCC 55056 0.58 CSW01_12265 carboxylating nicotinate-nucleotide diphosphorylase 0.63 CSW01_11575 glutamate 5-kinase low > 62
Shewanella sp. ANA-3 0.55 Shewana3_0422 nicotinate-nucleotide pyrophosphorylase [carboxylating] (RefSeq) 0.58 Shewana3_0954 gamma-glutamyl kinase (RefSeq) — —
Shewanella loihica PV-4 0.54 Shew_3435 nicotinate-nucleotide pyrophosphorylase (RefSeq) 0.62 Shew_2848 gamma-glutamyl kinase (RefSeq) — —
Alteromonas macleodii MIT1002 0.52 MIT1002_03008 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.35 MIT1002_04056 Glutamate 5-kinase — —
Pseudomonas stutzeri RCH2 0.52 Psest_0718 nicotinate-nucleotide pyrophosphorylase 0.36 Psest_3384 glutamate 5-kinase 0.47 6
Pseudomonas syringae pv. syringae B728a 0.51 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.37 Psyr_0704 glutamate 5-kinase 0.66 23
Pseudomonas syringae pv. syringae B728a ΔmexB 0.51 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.37 Psyr_0704 glutamate 5-kinase low > 86
Pseudomonas fluorescens FW300-N2E3 0.50 AO353_05520 nicotinate-nucleotide pyrophosphorylase 0.38 AO353_14115 gamma-glutamyl kinase 0.33 83
Pseudomonas sp. RS175 0.50 PFR28_00098 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.37 PFR28_03769 Glutamate 5-kinase — —
Pseudomonas putida KT2440 0.49 PP_0787 quinolinate phosphoribosyltransferase (decarboxylating) monomer 0.37 PP_0691 Glutamate 5-kinase low > 96
Pseudomonas fluorescens SBW25-INTG 0.49 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase 0.40 PFLU_RS25360 glutamate 5-kinase low > 109
Pseudomonas fluorescens SBW25 0.49 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase 0.40 PFLU_RS25360 glutamate 5-kinase low > 109
Acinetobacter radioresistens SK82 0.49 MPMX26_00042 Nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.35 MPMX26_02135 Glutamate 5-kinase low > 36
Pseudomonas fluorescens FW300-N1B4 0.48 Pf1N1B4_1153 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.39 Pf1N1B4_2800 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA — —
Marinobacter adhaerens HP15 0.48 HP15_1305 nicotinate-nucleotide pyrophosphorylase 0.34 HP15_508 gamma-glutamyl kinase — —
Pseudomonas fluorescens FW300-N2E2 0.48 Pf6N2E2_3346 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.37 Pf6N2E2_5103 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA low > 103
Pseudomonas simiae WCS417 0.48 PS417_03925 nicotinate-nucleotide pyrophosphorylase 0.39 PS417_23545 gamma-glutamyl kinase 0.36 62
Pseudomonas fluorescens FW300-N2C3 0.48 AO356_07370 nicotinate-nucleotide pyrophosphorylase 0.37 AO356_15815 gamma-glutamyl kinase 0.35 85
Pseudomonas sp. S08-1 0.48 OH686_16520 nicotinate-nucleotide diphosphorylase (carboxylating) 0.37 OH686_16305 Glutamate 5-kinase / RNA-binding C-terminal domain PUA low > 80
Pseudomonas fluorescens GW456-L13 0.47 PfGW456L13_5082 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.37 PfGW456L13_1472 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.64 19
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS13795 carboxylating nicotinate-nucleotide diphosphorylase 0.34 LRK54_RS02375 glutamate 5-kinase low > 59
Rhodanobacter denitrificans MT42 0.45 LRK55_RS13510 carboxylating nicotinate-nucleotide diphosphorylase 0.34 LRK55_RS02130 glutamate 5-kinase low > 63
Dyella japonica UNC79MFTsu3.2 0.45 ABZR86_RS09850 carboxylating nicotinate-nucleotide diphosphorylase 0.30 ABZR86_RS08685 glutamate 5-kinase low > 74
Dechlorosoma suillum PS 0.44 Dsui_2901 nicotinate-nucleotide pyrophosphorylase 0.41 Dsui_0166 glutamate 5-kinase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.42 GFF1217 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.35 GFF1274 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA low > 90
Ralstonia solanacearum PSI07 0.42 RPSI07_RS12655 nicotinate-nucleotide diphosphorylase (carboxylating) 0.36 RPSI07_RS11095 glutamate 5-kinase low > 81
Ralstonia sp. UNC404CL21Col 0.41 ABZR87_RS00350 carboxylating nicotinate-nucleotide diphosphorylase 0.36 ABZR87_RS01810 glutamate 5-kinase low > 80
Ralstonia solanacearum IBSBF1503 0.41 RALBFv3_RS04730 nicotinate-nucleotide diphosphorylase (carboxylating) 0.37 RALBFv3_RS06145 glutamate 5-kinase low > 76
Ralstonia solanacearum UW163 0.41 UW163_RS08940 nicotinate-nucleotide diphosphorylase (carboxylating) 0.37 UW163_RS07480 glutamate 5-kinase — —
Acidovorax sp. GW101-3H11 0.40 Ac3H11_3838 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.36 Ac3H11_4771 Glutamate 5-kinase (EC 2.7.2.11) 0.86 2
Herbaspirillum seropedicae SmR1 0.40 HSERO_RS11070 nicotinate-nucleotide pyrophosphorylase 0.38 HSERO_RS01815 gamma-glutamyl kinase 0.77 27
Cupriavidus basilensis FW507-4G11 0.40 RR42_RS17015 nicotinate-nucleotide pyrophosphorylase 0.37 RR42_RS17940 gamma-glutamyl kinase low > 128
Castellaniella sp019104865 MT123 0.39 ABCV34_RS03695 carboxylating nicotinate-nucleotide diphosphorylase 0.36 ABCV34_RS10800 glutamate 5-kinase low > 48
Paraburkholderia graminis OAS925 0.39 ABIE53_003293 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.37 ABIE53_003588 glutamate 5-kinase 0.22 98
Ralstonia solanacearum GMI1000 0.39 RS_RS12290 nicotinate-nucleotide diphosphorylase (carboxylating) 0.36 RS_RS14095 glutamate 5-kinase low > 80
Variovorax sp. OAS795 0.39 ABID97_RS07410 carboxylating nicotinate-nucleotide diphosphorylase 0.39 ABID97_RS23400 glutamate 5-kinase — —
Burkholderia phytofirmans PsJN 0.38 BPHYT_RS15645 nicotinate-nucleotide pyrophosphorylase 0.37 BPHYT_RS17110 glutamate 5-kinase — —
Paraburkholderia sabiae LMG 24235 0.38 QEN71_RS03065 carboxylating nicotinate-nucleotide diphosphorylase 0.37 QEN71_RS27270 glutamate 5-kinase 0.67 37
Paraburkholderia bryophila 376MFSha3.1 0.38 H281DRAFT_04070 nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.37 H281DRAFT_06264 glutamate 5-kinase low > 103
Lysobacter sp. OAE881 0.37 ABIE51_RS15405 carboxylating nicotinate-nucleotide diphosphorylase 0.31 ABIE51_RS13370 glutamate 5-kinase low > 62
Variovorax sp. SCN45 0.36 GFF2574 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.36 GFF2515 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA 0.46 101
Rhodopseudomonas palustris CGA009 0.35 TX73_005415 carboxylating nicotinate-nucleotide diphosphorylase 0.35 TX73_000850 glutamate 5-kinase — —
Xanthomonas campestris pv. campestris strain 8004 0.35 Xcc-8004.2009.1 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) 0.31 Xcc-8004.2326.1 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA low > 74
Bosea sp. OAE506 0.35 ABIE41_RS02500 carboxylating nicotinate-nucleotide diphosphorylase 0.33 ABIE41_RS07585 glutamate 5-kinase — —
Magnetospirillum magneticum AMB-1 0.34 AMB_RS19655 nicotinate-nucleotide diphosphorylase (carboxylating) 0.35 AMB_RS20630 glutamate 5-kinase — —
Rhizobium sp. OAE497 0.33 ABIE40_RS23265 carboxylating nicotinate-nucleotide diphosphorylase 0.36 ABIE40_RS18920 glutamate 5-kinase 0.61 4
Rhodospirillum rubrum S1H 0.33 Rru_A1432 Nicotinate-nucleotide pyrophosphorylase (NCBI) 0.33 Rru_A1239 Glutamate 5-kinase, ProB-related (NCBI) 0.55 46
Caulobacter crescentus NA1000 0.33 CCNA_03009 nicotinate-nucleotide pyrophosphorylase 0.35 CCNA_00316 glutamate 5-kinase — —
Caulobacter crescentus NA1000 Δfur 0.33 CCNA_03009 nicotinate-nucleotide pyrophosphorylase 0.35 CCNA_00316 glutamate 5-kinase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.33 A4249_RS00635 carboxylating nicotinate-nucleotide diphosphorylase 0.31 A4249_RS16125 glutamate 5-kinase low > 48
Parabacteroides merdae CL09T00C40 0.32 HMPREF1078_RS16725 carboxylating nicotinate-nucleotide diphosphorylase 0.28 HMPREF1078_RS10650 glutamate 5-kinase — —
Mycobacterium tuberculosis H37Rv 0.32 Rv1596 Probable nicotinate-nucleotide pyrophosphatase NadC 0.28 Rv2439c Probable glutamate 5-kinase protein ProB (gamma-glutamyl kinase) (GK) — —
Agrobacterium fabrum C58 0.32 Atu4096 nicotinate-nucleotide pyrophosphorylase 0.36 Atu2780 gamma-glutamyl kinase — —
Azospirillum sp. SherDot2 0.31 MPMX19_05672 putative nicotinate-nucleotide pyrophosphorylase [carboxylating] 0.36 MPMX19_01933 Glutamate 5-kinase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.31 ABZR88_RS15695 carboxylating nicotinate-nucleotide diphosphorylase 0.28 ABZR88_RS22170 glutamate 5-kinase — —
Pedobacter sp. GW460-11-11-14-LB5 0.31 CA265_RS14530 nicotinate-nucleotide diphosphorylase (carboxylating) 0.27 CA265_RS20855 glutamate 5-kinase (EC 2.7.2.11) (from data) low > 88
Bacteroides ovatus ATCC 8483 0.31 BACOVA_04303 nicotinate-nucleotide diphosphorylase (carboxylating) 0.26 BACOVA_03537 glutamate 5-kinase 0.89 4
Pontibacter actiniarum KMM 6156, DSM 19842 0.31 CA264_16940 nicotinate-nucleotide diphosphorylase (carboxylating) 0.28 CA264_07725 glutamate 5-kinase — —
Bacteroides stercoris CC31F 0.30 HMPREF1181_RS10745 carboxylating nicotinate-nucleotide diphosphorylase 0.26 HMPREF1181_RS03325 glutamate 5-kinase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.30 Echvi_1158 nicotinate-nucleotide pyrophosphorylase 0.29 Echvi_4033 glutamate 5-kinase (EC 2.7.2.11) (from data) low > 79
Bacteroides thetaiotaomicron VPI-5482 0.30 BT1560 nicotinate-nucleotide pyrophosphorylase (NCBI ptt file) 0.25 BT3719 glutamate 5-kinase (EC 2.7.2.11) (from data) — —
Bifidobacterium breve UCC2003 0.30 BBR_RS16720 nicotinate-nucleotide diphosphorylase (carboxylating) 0.32 BBR_RS19445 glutamate 5-kinase low > 34
Phocaeicola dorei CL03T12C01 0.30 ABI39_RS11900 carboxylating nicotinate-nucleotide diphosphorylase 0.24 ABI39_RS02880 glutamate 5-kinase — —
Phocaeicola vulgatus CL09T03C04 0.30 HMPREF1058_RS15940 carboxylating nicotinate-nucleotide diphosphorylase 0.25 HMPREF1058_RS08650 glutamate 5-kinase — —
Sphingomonas koreensis DSMZ 15582 0.29 Ga0059261_0061 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) 0.22 Ga0059261_3512 glutamate 5-kinase (EC 2.7.2.11) (from data) — —
Phaeobacter inhibens DSM 17395 0.28 PGA1_c27810 nicotinate-nucleotide pyrophosphorylase 0.34 PGA1_c15510 glutamate 5-kinase ProB low > 62
Synechococcus elongatus PCC 7942 0.27 Synpcc7942_0951 nadC nicotinate-nucleotide pyrophosphorylase 0.38 Synpcc7942_2197 proB gamma-glutamyl kinase — —
Sinorhizobium meliloti 1021 0.25 SMc02598 nicotinate-nucleotide pyrophosphorylase carboxylating protein 0.36 SMc03776 gamma-glutamyl kinase low > 103

Not shown: 4 genomes with orthologs for b0109 only; 6 genomes with orthologs for b0242 only