| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BW25113 | 1.0 | b0074 | leuA | 2-isopropylmalate synthase (NCBI) | 1.0 | b0072 | leuC | isopropylmalate isomerase large subunit (NCBI) | 0.99 | 1 |
| Escherichia coli BL21 | 1.00 | ECD_00076 | | 2-isopropylmalate synthase | 1.00 | ECD_00074 | | 3-isopropylmalate dehydratase large subunit | 0.76 | 4 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_03583 | | 2-isopropylmalate synthase | 1.00 | OHPLBJKB_03585 | | 3-isopropylmalate dehydratase large subunit | low | > 73 |
| Escherichia coli ECOR38 | 1.00 | HEPCGN_08695 | | 2-isopropylmalate synthase | 1.00 | HEPCGN_08705 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | low | > 85 |
| Escherichia coli ECRC62 | 1.00 | BNILDI_08550 | | 2-isopropylmalate synthase | 1.00 | BNILDI_08540 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECOR27 | 1.00 | NOLOHH_03060 | | 2-isopropylmalate synthase | 1.00 | NOLOHH_03070 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | low | > 57 |
| Escherichia fergusonii Becca | 1.00 | EFB2_03971 | | 2-isopropylmalate synthase | 1.00 | EFB2_03973 | | 3-isopropylmalate dehydratase large subunit | low | > 86 |
| Escherichia coli Nissle 1917 | 1.00 | ECOLIN_RS00400 | | 2-isopropylmalate synthase | 1.00 | ECOLIN_RS00390 | | 3-isopropylmalate dehydratase large subunit | low | > 52 |
| Escherichia coli ECRC101 | 1.00 | OKFHMN_10715 | | 2-isopropylmalate synthase | 1.00 | OKFHMN_10725 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC101 | 1.00 | MCAODC_01230 | | 2-isopropylmalate synthase | 1.00 | MCAODC_01240 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_17440 | | 2-isopropylmalate synthase | 1.00 | KEDOAH_17430 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_08565 | | 2-isopropylmalate synthase | 1.00 | NIAGMN_08575 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_14310 | | 2-isopropylmalate synthase | 1.00 | JDDGAC_14320 | leuC1 | 3-isopropylmalate dehydratase large subunit 1 | — | — |
| Klebsiella michiganensis M5al | 0.95 | BWI76_RS04680 | | 2-isopropylmalate synthase | 0.95 | BWI76_RS04670 | | 3-isopropylmalate dehydratase large subunit | 0.96 | 3 |
| Enterobacter asburiae PDN3 | 0.94 | EX28DRAFT_3670 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.95 | EX28DRAFT_3668 | | 3-isopropylmalate dehydratase, large subunit | 0.97 | 1 |
| Enterobacter sp. TBS_079 | 0.94 | MPMX20_00769 | | 2-isopropylmalate synthase | 0.94 | MPMX20_00767 | | 3-isopropylmalate dehydratase large subunit 1 | 0.97 | 2 |
| Pectobacterium carotovorum WPP14 | 0.87 | HER17_RS03085 | | 2-isopropylmalate synthase | 0.86 | HER17_RS03075 | | 3-isopropylmalate dehydratase large subunit | 0.99 | 3 |
| Erwinia tracheiphila SCR3 | 0.86 | LU632_RS02880 | leuA | 2-isopropylmalate synthase | 0.79 | LU632_RS02870 | leuC | 3-isopropylmalate dehydratase large subunit | 0.94 | 3 |
| Dickeya dianthicola 67-19 | 0.86 | HGI48_RS18055 | | 2-isopropylmalate synthase | 0.85 | HGI48_RS18065 | | 3-isopropylmalate dehydratase large subunit | 0.90 | 4 |
| Dickeya dadantii 3937 | 0.86 | DDA3937_RS18115 | | 2-isopropylmalate synthase | 0.85 | DDA3937_RS18125 | | 3-isopropylmalate dehydratase large subunit | 0.96 | 1 |
| Dickeya dianthicola ME23 | 0.86 | DZA65_RS19200 | | 2-isopropylmalate synthase | 0.85 | DZA65_RS19210 | | 3-isopropylmalate dehydratase large subunit | 0.94 | 2 |
| Serratia liquefaciens MT49 | 0.85 | IAI46_03355 | | 2-isopropylmalate synthase | 0.86 | IAI46_03345 | | 3-isopropylmalate dehydratase large subunit | 0.63 | 33 |
| Pantoea sp. MT58 | 0.84 | IAI47_16000 | | 2-isopropylmalate synthase | 0.87 | IAI47_16010 | | 3-isopropylmalate dehydratase large subunit | 0.99 | 1 |
| Rahnella sp. WP5 | 0.82 | EX31_RS03680 | | 2-isopropylmalate synthase | 0.87 | EX31_RS03690 | | 3-isopropylmalate dehydratase large subunit | 0.96 | 3 |
| Vibrio cholerae E7946 ATCC 55056 | 0.69 | CSW01_12595 | | 2-isopropylmalate synthase | 0.80 | CSW01_12605 | | 3-isopropylmalate dehydratase large subunit | low | > 62 |
| Shewanella amazonensis SB2B | 0.67 | Sama_0335 | | 2-isopropylmalate synthase (RefSeq) | 0.72 | Sama_0337 | | isopropylmalate isomerase large subunit (RefSeq) | 0.98 | 1 |
| Shewanella sp. ANA-3 | 0.66 | Shewana3_3761 | | 2-isopropylmalate synthase (RefSeq) | 0.73 | Shewana3_3759 | | isopropylmalate isomerase large subunit (RefSeq) | 0.99 | 1 |
| Shewanella oneidensis MR-1 | 0.66 | SO4236 | leuA | 2-isopropylmalate synthase (NCBI ptt file) | 0.73 | SO4234 | leuC | 3-isopropylmalate dehydratase, large subunit (NCBI ptt file) | 0.99 | 2 |
| Shewanella loihica PV-4 | 0.66 | Shew_3472 | | 2-isopropylmalate synthase (RefSeq) | 0.71 | Shew_3470 | | isopropylmalate isomerase large subunit (RefSeq) | 0.99 | 9 |
| Alteromonas macleodii MIT1002 | 0.62 | MIT1002_00949 | | 2-isopropylmalate synthase | 0.69 | MIT1002_00947 | | 3-isopropylmalate dehydratase large subunit | 0.99 | 8 |
| Pseudomonas stutzeri RCH2 | 0.47 | Psest_1056 | | 2-isopropylmalate synthase, bacterial type | 0.63 | Psest_2591 | | 3-isopropylmalate dehydratase, large subunit | low | > 67 |
| Dechlorosoma suillum PS | 0.46 | Dsui_3519 | | 2-isopropylmalate synthase, bacterial type | 0.60 | Dsui_3201 | | 3-isopropylmalate dehydratase, large subunit | — | — |
| Marinobacter adhaerens HP15 | 0.45 | HP15_538 | | 2-isopropylmalate synthase | 0.62 | HP15_1834 | | protein containing 3-isopropylmalate dehydratase, large subunit region domain | low | > 73 |
| Desulfovibrio vulgaris Miyazaki F | 0.44 | DvMF_1791 | | 2-isopropylmalate synthase (RefSeq) | 0.21 | DvMF_1792 | | 3-isopropylmalate dehydratase large subunit (RefSeq) | 0.96 | 1 |
| Phocaeicola vulgatus CL09T03C04 | 0.44 | HMPREF1058_RS14545 | | 2-isopropylmalate synthase | 0.51 | HMPREF1058_RS14550 | | 3-isopropylmalate dehydratase large subunit | 0.78 | 42 |
| Phocaeicola dorei CL03T12C01 | 0.44 | ABI39_RS10195 | | 2-isopropylmalate synthase | 0.51 | ABI39_RS10200 | | 3-isopropylmalate dehydratase large subunit | 0.89 | 1 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.43 | DVU2981 | leuA | 2-isopropylmalate synthase (TIGR) | 0.21 | DVU2982 | leuC | 3-isopropylmalate dehydratase / (R)-citramalate isomerase, large subunit LeuC (EC 4.2.1.33; EC 4.2.1.35) (from data) | 0.98 | 2 |
| Parabacteroides merdae CL09T00C40 | 0.43 | HMPREF1078_RS16665 | | 2-isopropylmalate synthase | 0.50 | HMPREF1078_RS16660 | | 3-isopropylmalate dehydratase large subunit | 0.98 | 2 |
| Bacteroides stercoris CC31F | 0.42 | HMPREF1181_RS14150 | | 2-isopropylmalate synthase | 0.52 | HMPREF1181_RS14145 | | 3-isopropylmalate dehydratase large subunit | 0.97 | 1 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.42 | H281DRAFT_04556 | | 2-isopropylmalate synthase | 0.62 | H281DRAFT_06075 | | 3-isopropylmalate dehydratase, large subunit | low | > 103 |
| Magnetospirillum magneticum AMB-1 | 0.42 | AMB_RS17765 | | 2-isopropylmalate synthase | 0.65 | AMB_RS20560 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Paraburkholderia graminis OAS925 | 0.42 | ABIE53_001580 | | 2-isopropylmalate synthase | 0.62 | ABIE53_004801 | | 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit | low | > 113 |
| Ralstonia solanacearum PSI07 | 0.42 | RPSI07_RS14285 | | 2-isopropylmalate synthase | 0.62 | RPSI07_RS14695 | | 3-isopropylmalate dehydratase large subunit | 0.43 | 18 |
| Ralstonia solanacearum UW163 | 0.42 | UW163_RS10700 | | 2-isopropylmalate synthase | 0.62 | UW163_RS11105 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.42 | RALBFv3_RS03025 | | 2-isopropylmalate synthase | 0.62 | RALBFv3_RS02620 | | 3-isopropylmalate dehydratase large subunit | low | > 76 |
| Ralstonia solanacearum GMI1000 | 0.42 | RS_RS10395 | | 2-isopropylmalate synthase | 0.62 | RS_RS10000 | | 3-isopropylmalate dehydratase large subunit | low | > 80 |
| Burkholderia phytofirmans PsJN | 0.42 | BPHYT_RS06570 | | 2-isopropylmalate synthase | 0.62 | BPHYT_RS33915 | | isopropylmalate isomerase | low | > 109 |
| Bacteroides ovatus ATCC 8483 | 0.42 | BACOVA_04604 | | 2-isopropylmalate synthase | 0.52 | BACOVA_04603 | | 3-isopropylmalate dehydratase, large subunit | 0.95 | 8 |
| Ralstonia sp. UNC404CL21Col | 0.42 | ABZR87_RS14930 | | 2-isopropylmalate synthase | 0.63 | ABZR87_RS14540 | | 3-isopropylmalate dehydratase large subunit | low | > 80 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.42 | BT1861 | | 2-isopropylmalate synthase (EC 2.3.3.13) (from data) | 0.51 | BT1860 | | 3-isopropylmalate dehydratase large subunit (NCBI ptt file) | 0.90 | 24 |
| Paraburkholderia sabiae LMG 24235 | 0.42 | QEN71_RS24195 | | 2-isopropylmalate synthase | 0.62 | QEN71_RS17605 | | 3-isopropylmalate dehydratase large subunit | low | > 153 |
| Rhodopseudomonas palustris CGA009 | 0.42 | TX73_010545 | | 2-isopropylmalate synthase | 0.62 | TX73_001245 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.42 | RR42_RS05465 | | 2-isopropylmalate synthase | 0.63 | RR42_RS14400 | | isopropylmalate isomerase | 0.39 | 9 |
| Bosea sp. OAE506 | 0.41 | ABIE41_RS13000 | | 2-isopropylmalate synthase | 0.63 | ABIE41_RS11660 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.41 | GFF4281 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.60 | GFF3363 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.58 | 21 |
| Synechococcus elongatus PCC 7942 | 0.41 | Synpcc7942_1410 | leuA | 2-isopropylmalate synthase | 0.51 | Synpcc7942_1898 | leuC | isopropylmalate isomerase large subunit | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.41 | ABZR86_RS15970 | | 2-isopropylmalate synthase | 0.51 | ABZR86_RS15960 | | 3-isopropylmalate dehydratase large subunit | 0.98 | 2 |
| Variovorax sp. OAS795 | 0.41 | ABID97_RS14910 | | 2-isopropylmalate synthase | 0.60 | ABID97_RS08465 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Acidovorax sp. GW101-3H11 | 0.41 | Ac3H11_530 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.59 | Ac3H11_1525 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.39 | 57 |
| Variovorax sp. SCN45 | 0.41 | GFF1165 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.60 | GFF3890 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | low | > 127 |
| Caulobacter crescentus NA1000 Δfur | 0.40 | CCNA_01610 | | 2-isopropylmalate synthase | 0.61 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | low | > 67 |
| Caulobacter crescentus NA1000 | 0.40 | CCNA_01610 | | 2-isopropylmalate synthase | 0.61 | CCNA_00196 | | 3-isopropylmalate dehydratase large subunit | 0.83 | 24 |
| Lysobacter sp. OAE881 | 0.40 | ABIE51_RS17570 | | 2-isopropylmalate synthase | 0.53 | ABIE51_RS17575 | | 3-isopropylmalate dehydratase large subunit | 0.86 | 21 |
| Phaeobacter inhibens DSM 17395 | 0.40 | PGA1_c26470 | | 2-isopropylmalate synthase LeuA | 0.62 | PGA1_c29780 | | 3-isopropylmalate dehydratase large subunit | 0.95 | 2 |
| Rhodanobacter denitrificans FW104-10B01 | 0.39 | LRK54_RS10345 | | 2-isopropylmalate synthase | 0.54 | LRK54_RS07375 | | 3-isopropylmalate dehydratase large subunit | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.39 | LRK55_RS09985 | | 2-isopropylmalate synthase | 0.54 | LRK55_RS07105 | | 3-isopropylmalate dehydratase large subunit | low | > 63 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.39 | Xcc-8004.1056.1 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.63 | Xcc-8004.1049.1 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.89 | 2 |
| Rhodanobacter sp. FW510-T8 | 0.38 | OKGIIK_13575 | leuA | 2-isopropylmalate synthase | 0.49 | OKGIIK_13585 | leuC | 3-isopropylmalate dehydratase large subunit | low | > 52 |
| Dinoroseobacter shibae DFL-12 | 0.38 | Dshi_0596 | | 2-isopropylmalate synthase (RefSeq) | 0.61 | Dshi_0085 | | 3-isopropylmalate dehydratase, large subunit (RefSeq) | 0.75 | 22 |
| Methanococcus maripaludis JJ | 0.29 | MMJJ_RS08870 | | 2-isopropylmalate synthase | 0.23 | MMJJ_RS08425 | | 3-isopropylmalate dehydratase large subunit | — | — |
| Methanococcus maripaludis S2 | 0.28 | MMP_RS05500 | | 2-isopropylmalate synthase | 0.23 | MMP_RS05930 | | 3-isopropylmalate dehydratase large subunit | 0.73 | 9 |
| Sinorhizobium meliloti 1021 | 0.15 | SMc02546 | | alpha-isopropylmalate/homocitrate synthase family transferase | 0.66 | SMc03823 | | isopropylmalate isomerase large subunit | low | > 103 |
| Rhizobium sp. OAE497 | 0.15 | ABIE40_RS06220 | | citramalate synthase | 0.64 | ABIE40_RS18380 | | 3-isopropylmalate dehydratase large subunit | 0.69 | 10 |
| Pseudomonas sp. S08-1 | 0.12 | OH686_17570 | | 2-isopropylmalate synthase | 0.63 | OH686_04480 | | 3-isopropylmalate dehydratase large subunit | 0.76 | 7 |
| Sphingomonas koreensis DSMZ 15582 | 0.12 | Ga0059261_4031 | | 2-isopropylmalate synthase, yeast type | 0.59 | Ga0059261_4223 | | 3-isopropylmalate dehydratase, large subunit | 0.99 | 2 |
| Pseudomonas fluorescens FW300-N2C3 | 0.11 | AO356_06550 | | 2-isopropylmalate synthase | 0.62 | AO356_21400 | | isopropylmalate isomerase | 0.96 | 2 |
| Pseudomonas fluorescens FW300-N2E2 | 0.11 | Pf6N2E2_3170 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.62 | Pf6N2E2_63 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.87 | 15 |
| Acinetobacter radioresistens SK82 | 0.10 | MPMX26_00404 | | 2-isopropylmalate synthase | 0.62 | MPMX26_00345 | | 3-isopropylmalate dehydratase large subunit | 0.92 | 6 |
| Pseudomonas sp. RS175 | 0.10 | PFR28_00305 | | 2-isopropylmalate synthase | 0.62 | PFR28_02824 | | 3-isopropylmalate dehydratase large subunit | 0.81 | 2 |
| Castellaniella sp019104865 MT123 | 0.10 | ABCV34_RS12420 | | 2-isopropylmalate synthase | 0.62 | ABCV34_RS04290 | | 3-isopropylmalate dehydratase large subunit | low | > 48 |
| Pseudomonas fluorescens GW456-L13 | 0.10 | PfGW456L13_4854 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.62 | PfGW456L13_3948 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.97 | 2 |
| Pseudomonas fluorescens FW300-N1B4 | 0.10 | Pf1N1B4_847 | | 2-isopropylmalate synthase (EC 2.3.3.13) | 0.62 | Pf1N1B4_15 | | 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) | 0.94 | 3 |
| Agrobacterium fabrum C58 | 0.10 | Atu2264 | | 2-isopropylmalate synthase | 0.64 | Atu2709 | | 3-isopropylmalate dehydratase, large subunit | 0.99 | 1 |
| Pseudomonas putida KT2440 | 0.10 | PP_1025 | | 2-isopropylmalate synthase | 0.61 | PP_1985 | | 3-isopropylmalate dehydratase large subunit | 0.88 | 2 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.10 | Psyr_1257 | | 2-isopropylmalate synthase | 0.62 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | 0.94 | 5 |
| Pseudomonas simiae WCS417 | 0.10 | PS417_23110 | | 2-isopropylmalate synthase | 0.61 | PS417_18600 | | isopropylmalate isomerase | 0.93 | 2 |
| Pseudomonas fluorescens SBW25 | 0.10 | PFLU_RS24765 | | 2-isopropylmalate synthase | 0.62 | PFLU_RS20580 | | 3-isopropylmalate dehydratase large subunit | 0.92 | 2 |
| Pseudomonas syringae pv. syringae B728a | 0.10 | Psyr_1257 | | 2-isopropylmalate synthase | 0.62 | Psyr_1983 | | 3-isopropylmalate dehydratase, large subunit | 0.94 | 1 |
| Pseudomonas fluorescens SBW25-INTG | 0.10 | PFLU_RS24765 | | 2-isopropylmalate synthase | 0.62 | PFLU_RS20580 | | 3-isopropylmalate dehydratase large subunit | 0.95 | 1 |
Not shown: 0 genomes with orthologs for b0074 only; 14 genomes with orthologs for b0072 only